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Items: 35


Non-invasive Optical Biomarkers Distinguish and Track the Metabolic Status of Single Hematopoietic Stem Cells.

Zhou H, Nguyen L, Arnesano C, Ando Y, Raval M, Rodgers JT, Fraser S, Lu R, Shen K.

iScience. 2020 Jan 10;23(2):100831. doi: 10.1016/j.isci.2020.100831. [Epub ahead of print]


Numerical Analysis of Time-Dependent Inhibition by MDMA.

Rodgers JT, Jones JP.

Drug Metab Dispos. 2020 Jan;48(1):1-7. doi: 10.1124/dmd.119.089268. Epub 2019 Oct 22.


Time Course of Aldehyde Oxidase and Why It Is Nonlinear.

Abbasi A, Paragas EM, Joswig-Jones CA, Rodgers JT, Jones JP.

Drug Metab Dispos. 2019 May;47(5):473-483. doi: 10.1124/dmd.118.085787. Epub 2019 Feb 20.


Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): Functional heterogeneity of the enzyme and the reversibility of its inactivation.

Rodgers JT, Davydova NY, Paragas EM, Jones JP, Davydov DR.

Biochem Pharmacol. 2018 Oct;156:86-98. doi: 10.1016/j.bcp.2018.08.010. Epub 2018 Aug 13.


mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.

Haller S, Kapuria S, Riley RR, O'Leary MN, Schreiber KH, Andersen JK, Melov S, Que J, Rando TA, Rock J, Kennedy BK, Rodgers JT, Jasper H.

Cell Stem Cell. 2017 Dec 7;21(6):806-818.e5. doi: 10.1016/j.stem.2017.11.008.


Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.

Davydov DR, Davydova NY, Rodgers JT, Rushmore TH, Jones JP.

Biochem J. 2017 Oct 10;474(20):3523-3542. doi: 10.1042/BCJ20170543.


HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert.

Rodgers JT, Schroeder MD, Ma C, Rando TA.

Cell Rep. 2017 Apr 18;19(3):479-486. doi: 10.1016/j.celrep.2017.03.066.


Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche.

Rodgers JT.

Cell Stem Cell. 2016 Aug 4;19(2):150-151. doi: 10.1016/j.stem.2016.07.008.


mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).

Rodgers JT, King KY, Brett JO, Cromie MJ, Charville GW, Maguire KK, Brunson C, Mastey N, Liu L, Tsai CR, Goodell MA, Rando TA.

Nature. 2014 Jun 19;510(7505):393-6. doi: 10.1038/nature13255. Epub 2014 May 25.


Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB.

Nature. 2014 Apr 10;508(7495):258-62. doi: 10.1038/nature13198.


USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy.

Hall JA, Tabata M, Rodgers JT, Puigserver P.

Mol Endocrinol. 2014 Jun;28(6):912-24. doi: 10.1210/me.2013-1420. Epub 2014 Apr 2.


Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex.

Tabata M, Rodgers JT, Hall JA, Lee Y, Jedrychowski MP, Gygi SP, Puigserver P.

Diabetes. 2014 May;63(5):1519-32. doi: 10.2337/db13-1304. Epub 2014 Jan 23.


Healthcare navigation service in 2-1-1 San Diego: guiding individuals to the care they need.

Rodgers JT, Purnell JQ.

Am J Prev Med. 2012 Dec;43(6 Suppl 5):S450-6. doi: 10.1016/j.amepre.2012.08.012.


Sprouting a new take on stem cell aging.

Rodgers JT, Rando TA.

EMBO J. 2012 Nov 5;31(21):4103-5. doi: 10.1038/emboj.2012.281. Epub 2012 Oct 5. No abstract available.


Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.

Rodgers JT, Vogel RO, Puigserver P.

Mol Cell. 2011 Feb 18;41(4):471-9. doi: 10.1016/j.molcel.2011.02.007.


Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM.

Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.


Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis.

Rodgers JT, Haas W, Gygi SP, Puigserver P.

Cell Metab. 2010 Jan;11(1):23-34. doi: 10.1016/j.cmet.2009.11.006.


Foxo1 integrates insulin signaling with mitochondrial function in the liver.

Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF.

Nat Med. 2009 Nov;15(11):1307-11. doi: 10.1038/nm.2049. Epub 2009 Oct 18.


Insulin resistance: beta-arrestin development.

Rodgers JT, Puigserver P.

Cell Res. 2009 Mar;19(3):275-6. doi: 10.1038/cr.2009.22. No abstract available.


A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.

Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW.

J Biol Chem. 2009 Feb 20;284(8):5148-57. doi: 10.1074/jbc.M808890200. Epub 2008 Dec 22.


O-GlcNAc regulates FoxO activation in response to glucose.

Housley MP, Rodgers JT, Udeshi ND, Kelly TJ, Shabanowitz J, Hunt DF, Puigserver P, Hart GW.

J Biol Chem. 2008 Jun 13;283(24):16283-92. doi: 10.1074/jbc.M802240200. Epub 2008 Apr 17.


mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.

Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P.

Nature. 2007 Nov 29;450(7170):736-40.


Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways.

Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P.

FEBS Lett. 2008 Jan 9;582(1):46-53. Epub 2007 Nov 26. Review.


Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1.

Rodgers JT, Puigserver P.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12861-6. Epub 2007 Jul 23.


SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH.

EMBO J. 2007 Jul 11;26(13):3169-79. Epub 2007 Jun 21.


Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.

Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P.

EMBO J. 2007 Apr 4;26(7):1913-23. Epub 2007 Mar 8.


Receptor feasts on sugar and cholesterol.

Rodgers JT, Puigserver P.

Nat Med. 2007 Feb;13(2):128-9. No abstract available.


Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.

Cha SH, Rodgers JT, Puigserver P, Chohnan S, Lane MD.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15410-5. Epub 2006 Oct 9.


GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha.

Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A, Puigserver P.

Cell Metab. 2006 Jun;3(6):429-38.


Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.

Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, Sauve AA, Pasinetti GM.

J Biol Chem. 2006 Aug 4;281(31):21745-54. Epub 2006 Jun 2.


Certainly can't live without this: SIRT6.

Rodgers JT, Puigserver P.

Cell Metab. 2006 Feb;3(2):77-8.


Foxa2, a novel transcriptional regulator of insulin sensitivity.

Puigserver P, Rodgers JT.

Nat Med. 2006 Jan;12(1):38-9. No abstract available.


Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P.

Nature. 2005 Mar 3;434(7029):113-8.


Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules.

Vercoutere WA, Winters-Hilt S, DeGuzman VS, Deamer D, Ridino SE, Rodgers JT, Olsen HE, Marziali A, Akeson M.

Nucleic Acids Res. 2003 Feb 15;31(4):1311-8.


Use of biotin-labeled nucleic acids for protein purification and agarose-based chemiluminescent electromobility shift assays.

Rodgers JT, Patel P, Hennes JL, Bolognia SL, Mascotti DP.

Anal Biochem. 2000 Jan 15;277(2):254-9.


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