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Items: 1 to 50 of 113

1.

Maternal rat serum concentrations of dimethadione do not explain intra-litter differences in the incidence of dimethadione-induced birth defects, including novel findings in foetal lung.

Rodger I, Lam I, Purssell E, Thompson M, Rutter A, Ozolinš TR.

Toxicology. 2014 Dec 4;326:142-52. doi: 10.1016/j.tox.2014.10.014. Epub 2014 Nov 1.

PMID:
25446330
2.

Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study.

Rodger IW, Dilar D, Dwyer J, Bienenstock J, Coret A, Coret-Simon J, Foster G, Franchetto A, Franic S, Goldsmith CH, Koff D, Konyer NB, Levine M, McDonald E, Noseworthy MD, Paulseth J, Ribeiro L, Sayles MJ, Thabane L.

PLoS One. 2013 Aug 14;8(8):e72495. doi: 10.1371/journal.pone.0072495. eCollection 2013.

3.

Analgesic targets: today and tomorrow.

Rodger IW.

Inflammopharmacology. 2009 Jun;17(3):151-61. doi: 10.1007/s10787-009-0006-z. Epub 2009 Jun 9. Review.

PMID:
19507000
4.

Inhibition of COX pathway in experimental myocardial infarction.

Saito T, Rodger IW, Hu F, Robinson R, Huynh T, Giaid A.

J Mol Cell Cardiol. 2004 Jul;37(1):71-7.

PMID:
15242737
5.

A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis.

Zacher J, Feldman D, Gerli R, Scott D, Hou SM, Uebelhart D, Rodger IW, Ozturk ZE; etoricoxib OA study group.

Curr Med Res Opin. 2003;19(8):725-36. Erratum in: Curr Med Res Opin. 2004 Oct;20(10):1689.

PMID:
14687444
6.

Cyclooxygenase-2 (COX-2) in acute myocardial infarction: cellular expression and use of selective COX-2 inhibitor.

Saito T, Rodger IW, Shennib H, Hu F, Tayara L, Giaid A.

Can J Physiol Pharmacol. 2003 Feb;81(2):114-9.

PMID:
12710523
7.

Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.

Riendeau D, Percival MD, Brideau C, Charleson S, Dubé D, Ethier D, Falgueyret JP, Friesen RW, Gordon R, Greig G, Guay J, Mancini J, Ouellet M, Wong E, Xu L, Boyce S, Visco D, Girard Y, Prasit P, Zamboni R, Rodger IW, Gresser M, Ford-Hutchinson AW, Young RN, Chan CC.

J Pharmacol Exp Ther. 2001 Feb;296(2):558-66.

PMID:
11160644
8.

Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats.

Savoie C, Chan CC, Rodger IW, Robichaud A.

Can J Physiol Pharmacol. 2000 Sep;78(9):708-13. Erratum in: Can J Physiol Pharmacol 2001 Jan;79(1):93.

PMID:
11007533
9.

Inhibition of cyclooxygenase-2 improves cardiac function in myocardial infarction.

Saito T, Rodger IW, Hu F, Shennib H, Giaid A.

Biochem Biophys Res Commun. 2000 Jul 5;273(2):772-5.

PMID:
10873679
10.

Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease.

Taha R, Olivenstein R, Utsumi T, Ernst P, Barnes PJ, Rodger IW, Giaid A.

Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 1):636-40.

PMID:
10673210
11.

From bench to bedside. The hurdles of discovering a new leukotriene receptor antagonist.

Rodger IW.

Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 2):S7-S10. Review. No abstract available.

PMID:
10673218
12.

Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.

Chan CC, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Ford-Hutchinson AW, Forrest MJ, Gauthier JY, Gordon R, Gresser M, Guay J, Kargman S, Kennedy B, Leblanc Y, Leger S, Mancini J, O'Neill GP, Ouellet M, Patrick D, Percival MD, Perrier H, Prasit P, Rodger I, et al.

J Pharmacol Exp Ther. 1999 Aug;290(2):551-60.

PMID:
10411562
13.

The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor.

Prasit P, Wang Z, Brideau C, Chan CC, Charleson S, Cromlish W, Ethier D, Evans JF, Ford-Hutchinson AW, Gauthier JY, Gordon R, Guay J, Gresser M, Kargman S, Kennedy B, Leblanc Y, Léger S, Mancini J, O'Neill GP, Ouellet M, Percival MD, Perrier H, Riendeau D, Rodger I, Zamboni R, et al.

Bioorg Med Chem Lett. 1999 Jul 5;9(13):1773-8.

PMID:
10406640
14.

Role of leukotrienes and leukotriene receptor antagonists in asthma.

Jones TR, Rodger IW.

Pulm Pharmacol Ther. 1999;12(2):107-10. Review. No abstract available.

PMID:
10373391
15.

Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret.

Robichaud A, Tattersall FD, Choudhury I, Rodger IW.

Neuropharmacology. 1999 Feb;38(2):289-97.

PMID:
10218871
16.
17.

Differential effect of a selective cyclooxygenase-2 inhibitor versus indomethacin on renal blood flow in conscious volume-depleted dogs.

Black SC, Brideau C, Cirino M, Belley M, Bosquet J, Chan CC, Rodger IW.

J Cardiovasc Pharmacol. 1998 Nov;32(5):686-94.

PMID:
9821840
18.

Leukotrienes and the brain.

Morris AA, Rodger IW.

Lancet. 1998 Nov 7;352(9139):1487-8. No abstract available.

PMID:
9820293
19.

Carbohydrate ingestion immediately before exercise does not improve 20 km time trial performance in well trained cyclists.

Palmer GS, Clancy MC, Hawley JA, Rodger IM, Burke LM, Noakes TD.

Int J Sports Med. 1998 Aug;19(6):415-8.

PMID:
9774209
20.

Role of tachykinins in airway responses to ozone in rats.

Takebayashi T, Abraham J, Murthy GG, Lilly C, Rodger I, Shore SA.

J Appl Physiol (1985). 1998 Aug;85(2):442-50.

21.

Induction of cyclooxygenase-2 and activation of nuclear factor-kappaB in myocardium of patients with congestive heart failure.

Wong SC, Fukuchi M, Melnyk P, Rodger I, Giaid A.

Circulation. 1998 Jul 14;98(2):100-3.

PMID:
9679714
22.

Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma.

Jones TR, McAuliffe M, McFarlane CS, Piechuta H, Macdonald D, Rodger IW.

Can J Physiol Pharmacol. 1998 Feb;76(2):210-7.

PMID:
9635162
23.

Characterization of CHO-K1 cells stably expressing PDE-IV enzymes. Whole-cell cAMP determinations vs broken-cell enzymatic assays.

Pon DJ, Plant M, Tkach J, Boulet L, Muise E, Allen RA, Rodger IW.

Cell Biochem Biophys. 1998;29(1-2):159-78.

PMID:
9631244
24.

Co-localization of the cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat.

Black SC, Huang JQ, Rezaiefar P, Radinovic S, Eberhart A, Nicholson DW, Rodger IW.

J Mol Cell Cardiol. 1998 Apr;30(4):733-42.

PMID:
9602422
25.

Role of leukotrienes and leukotriene receptor antagonist in asthma: new advances.

Rodger IW.

J Investig Allergol Clin Immunol. 1997 Sep-Oct;7(5):279. Review. No abstract available.

PMID:
9416517
26.

Cardiovascular and renal actions of the endothelin(B) receptor in pigs.

Cirino M, Martin E, Yano M, Rodger IW.

J Cardiovasc Pharmacol. 1997 Jun;29(6):704-12.

PMID:
9234650
27.

A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates.

Chan CC, Panneton M, Taylor AM, Therien M, Rodger IW.

Eur J Pharmacol. 1997 May 30;327(2-3):221-5.

PMID:
9200563
28.

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.

Riendeau D, Percival MD, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Falgueyret JP, Ford-Hutchinson AW, Gordon R, Greig G, Gresser M, Guay J, Kargman S, Léger S, Mancini JA, O'Neill G, Ouellet M, Rodger IW, Thérien M, Wang Z, Webb JK, Wong E, Chan CC, et al.

Br J Pharmacol. 1997 May;121(1):105-17.

29.

Selective cyclooxygenase-2 inhibitors as potential therapeutic agents for inflammatory diseases.

Chan CC, Rodger IW.

Adv Exp Med Biol. 1997;407:157-61. Review. No abstract available.

PMID:
9321947
30.

One-month exposure to inhaled endotoxin produces a dose-dependent increase in stored mucosubstances in rat intrapulmonary airways.

Gordon T, Nadziejko C, Plant M, Rodger IW, Pon DJ.

Exp Lung Res. 1996 Sep-Oct;22(5):509-23.

PMID:
8886756
31.

Acute necrotising myopathy in a critically ill patient.

Rodger I.

Aust N Z J Med. 1996 Aug;26(4):560. No abstract available.

PMID:
8873944
32.

Methods for studying experimental myocardial ischemic and reperfusion injury.

Black SC, Rodger IW.

J Pharmacol Toxicol Methods. 1996 Aug;35(4):179-90. Review.

PMID:
8823664
33.

A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors.

Brideau C, Kargman S, Liu S, Dallob AL, Ehrich EW, Rodger IW, Chan CC.

Inflamm Res. 1996 Feb;45(2):68-74.

PMID:
8907587
34.
35.

Effect of dexamethasone on antigen-induced high molecular weight glycoconjugate secretion in allergic guinea pigs.

Savoie C, Plant M, Zwikker M, van Staden CJ, Boulet L, Chan CC, Rodger IW, Pon DJ.

Am J Respir Cell Mol Biol. 1995 Aug;13(2):133-43.

PMID:
7626283
36.

Neurokinin receptors subserving plasma extravasation in guinea pig airways.

Rodger IW, Tousignant C, Young D, Savoie C, Chan CC.

Can J Physiol Pharmacol. 1995 Jul;73(7):927-31.

PMID:
8846432
37.

Increased airway responsiveness to inhaled methacholine in a rat model of chronic bronchitis.

Shore S, Kobzik L, Long NC, Skornik W, Van Staden CJ, Boulet L, Rodger IW, Pon DJ.

Am J Respir Crit Care Med. 1995 Jun;151(6):1931-8.

PMID:
7767542
38.

Cigarette smoke-induced bronchoconstriction: cholinergic mechanisms, tachykinins, and cyclooxygenase products.

Hong JL, Rodger IW, Lee LY.

J Appl Physiol (1985). 1995 Jun;78(6):2260-6.

PMID:
7665427
39.

Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells.

White SR, Garland A, Gitter B, Rodger I, Alger LE, Necheles J, Nawrocki AR, Solway J.

Am J Physiol. 1995 Jun;268(6 Pt 1):L957-65.

PMID:
7611437
40.

Substance P-induced histamine release in tracheally perfused guinea pig lungs.

Lilly CM, Hall AE, Rodger IW, Kobzik L, Haley KJ, Drazen JM.

J Appl Physiol (1985). 1995 Apr;78(4):1234-41.

PMID:
7542231
41.

The effects of carbohydrate loading on muscle glycogen content and cycling performance.

Rauch LH, Rodger I, Wilson GR, Belonje JD, Dennis SC, Noakes TD, Hawley JA.

Int J Sport Nutr. 1995 Mar;5(1):25-36.

PMID:
7749423
42.

L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats.

Boyce S, Chan CC, Gordon R, Li CS, Rodger IW, Webb JK, Rupniak NM, Hill RG.

Neuropharmacology. 1994 Dec;33(12):1609-11.

PMID:
7760984
43.

Dual cardiovascular effects of endothelin-1 dissociated by BQ-153, a novel ETA receptor antagonist.

Cirino M, Battistini B, Yano M, Rodger IW.

J Cardiovasc Pharmacol. 1994 Oct;24(4):587-94.

PMID:
7528841
44.

Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells.

Pon DJ, van Staden CJ, Boulet L, Rodger IW.

Can J Physiol Pharmacol. 1994 Sep;72(9):1025-30.

PMID:
7842384
45.

Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists.

Chan CC, Ecclestone P, Nicholson DW, Metters KM, Pon DJ, Rodger IW.

J Pharmacol Exp Ther. 1994 Jun;269(3):891-6.

PMID:
8014876
46.
47.

Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.

Lilly CM, Besson G, Israel E, Rodger IW, Drazen JM.

Am J Respir Crit Care Med. 1994 May;149(5):1175-9.

PMID:
7513595
48.
49.
50.

Identification of both NK1 and NK2 receptors in guinea-pig airways.

McKee KT, Millar L, Rodger IW, Metters KM.

Br J Pharmacol. 1993 Oct;110(2):693-700.

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