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Items: 14

1.

An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene.

Yang S, Cheng YS, Li R, Pradhan M, Hong J, Beers J, Zou J, Liu C, Might M, Rodems S, Zheng W.

Stem Cell Res. 2019 Aug;39:101496. doi: 10.1016/j.scr.2019.101496. Epub 2019 Jul 9.

2.

Induced pluripotent stem cells for neural drug discovery.

Farkhondeh A, Li R, Gorshkov K, Chen KG, Might M, Rodems S, Lo DC, Zheng W.

Drug Discov Today. 2019 Apr;24(4):992-999. doi: 10.1016/j.drudis.2019.01.007. Epub 2019 Jan 18. Review.

3.

Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene.

Li R, Pradhan M, Xu M, Baskfield A, Farkhondeh A, Cheng YS, Beers J, Zou J, Liu C, Might M, Rodems S, Zheng W.

Stem Cell Res. 2019 Jan;34:101362. doi: 10.1016/j.scr.2018.101362. Epub 2018 Dec 5.

4.

Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity.

Bresciani A, Cecchetti O, Missineo A, Pacifici PG, Tomei L, Rodems S.

SLAS Discov. 2018 Oct;23(9):941-950. doi: 10.1177/2472555218782625. Epub 2018 Jun 22.

PMID:
29932789
5.

Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors.

Green J, Cao J, Bandarage UK, Gao H, Court J, Marhefka C, Jacobs M, Taslimi P, Newsome D, Nakayama T, Shah S, Rodems S.

J Med Chem. 2015 Jun 25;58(12):5028-37. doi: 10.1021/acs.jmedchem.5b00424. Epub 2015 Jun 12.

PMID:
26039570
6.

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.

Bandarage U, Hare B, Parsons J, Pham L, Marhefka C, Bemis G, Tang Q, Moody CS, Rodems S, Shah S, Adams C, Bravo J, Charonnet E, Savic V, Come JH, Green J.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5191-4. doi: 10.1016/j.bmcl.2009.07.022. Epub 2009 Jul 9.

PMID:
19632115
7.

A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases.

Rodems SM, Hamman BD, Lin C, Zhao J, Shah S, Heidary D, Makings L, Stack JH, Pollok BA.

Assay Drug Dev Technol. 2002 Nov;1(1 Pt 1):9-19.

PMID:
15090152
8.

A ubiquitin-based tagging system for controlled modulation of protein stability.

Stack JH, Whitney M, Rodems SM, Pollok BA.

Nat Biotechnol. 2000 Dec;18(12):1298-302.

PMID:
11101811
10.

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