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Items: 1 to 50 of 543

1.

An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring.

Starkman R, Alibhai S, Wells RA, Geddes M, Zhu N, Keating MM, Leber B, Chodirker L, Sabloff M, Christou G, Leitch HA, St-Hilaire E, Finn N, Shamy A, Yee K, Storring J, Nevill T, Delage R, Elemary M, Banerji V, Lenis M, Kirubananthaan A, Mamedov A, Zhang L, Rockwood K, Buckstein R.

Leukemia. 2019 Dec 6. doi: 10.1038/s41375-019-0666-7. [Epub ahead of print]

PMID:
31811236
2.

Association of fatty acid consumption with frailty and mortality among middle-aged and older adults.

Jayanama K, Theou O, Godin J, Cahill L, Rockwood K.

Nutrition. 2019 Oct 11;70:110610. doi: 10.1016/j.nut.2019.110610. [Epub ahead of print]

PMID:
31743811
3.

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.

Boxer AL, Gold M, Feldman H, Boeve BF, Dickinson SL, Fillit H, Ho C, Paul R, Pearlman R, Sutherland M, Verma A, Arneric SP, Alexander BM, Dickerson BC, Dorsey ER, Grossman M, Huey ED, Irizarry MC, Marks WJ, Masellis M, McFarland F, Niehoff D, Onyike CU, Paganoni S, Panzara MA, Rockwood K, Rohrer JD, Rosen H, Schuck RN, Soares HD, Tatton N.

Alzheimers Dement. 2019 Oct 23. pii: S1552-5260(19)35360-9. doi: 10.1016/j.jalz.2019.06.4956. [Epub ahead of print] Review.

PMID:
31668596
4.

Common risk factors for major noncommunicable disease, a systematic overview of reviews and commentary: the implied potential for targeted risk reduction.

Peters R, Ee N, Peters J, Beckett N, Booth A, Rockwood K, Anstey KJ.

Ther Adv Chronic Dis. 2019 Oct 15;10:2040622319880392. doi: 10.1177/2040622319880392. eCollection 2019. Review.

5.

Prediction of damage accrual in systemic lupus erythematosus using the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI).

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin PR, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG.

Arthritis Rheumatol. 2019 Oct 21. doi: 10.1002/art.41144. [Epub ahead of print]

PMID:
31631584
6.

Investigating the feasibility and reliability of the Pictorial Fit-Frail Scale.

McGarrigle L, Squires E, Wallace LMK, Godin J, Gorman M, Rockwood K, Theou O.

Age Ageing. 2019 Nov 1;48(6):832-837. doi: 10.1093/ageing/afz111.

PMID:
31579907
7.

An empirical validation of neuropsychiatric symptoms and agitation profiles in dementia using data from an online symptom tracking tool.

Rockwood K, Stanley J, McGarrigle L.

Int Psychogeriatr. 2019 Sep 23:1-2. doi: 10.1017/S1041610219001406. [Epub ahead of print] No abstract available.

PMID:
31543082
8.

Validation of the Pictorial Fit-Frail Scale in a memory clinic setting.

Wallace LMK, McGarrigle L, Rockwood K, Andrew MK, Theou O.

Int Psychogeriatr. 2019 Sep 16:1-10. doi: 10.1017/S1041610219000905. [Epub ahead of print]

PMID:
31524122
9.

Frailty and Diabetes in Older Hospitalized Adults: The Case for Routine Frailty Assessment.

MacKenzie HT, Tugwell B, Rockwood K, Theou O.

Can J Diabetes. 2019 Jul 6. pii: S1499-2671(19)30232-1. doi: 10.1016/j.jcjd.2019.07.001. [Epub ahead of print]

PMID:
31466827
10.

Genetic predisposition and modifiable risks for late-life dementia.

Rockwood K, Wallace LMK, Davis DH.

Nat Med. 2019 Sep;25(9):1331-1332. doi: 10.1038/s41591-019-0575-3. No abstract available.

PMID:
31451783
11.

Frailty and Risk of Incident Motoric Cognitive Risk Syndrome.

Sathyan S, Ayers E, Gao T, Milman S, Barzilai N, Rockwood K, Verghese J.

J Alzheimers Dis. 2019;71(s1):S85-S93. doi: 10.3233/JAD-190517.

PMID:
31450502
12.

Compression of frailty in adults living with HIV.

Guaraldi G, Francesco D, Malagoli A, Zona S, Franconi I, Santoro A, Mussini C, Mussi C, Cesari M, Theou O, Rockwood K.

BMC Geriatr. 2019 Aug 22;19(1):229. doi: 10.1186/s12877-019-1247-3.

13.

Upright time during hospitalization for older inpatients: A prospective cohort study.

Theou O, Kehler DS, Godin J, Mallery K, MacLean MA, Rockwood K.

Exp Gerontol. 2019 Oct 15;126:110681. doi: 10.1016/j.exger.2019.110681. Epub 2019 Aug 2.

PMID:
31382011
14.

The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study.

Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ.

Can J Neurol Sci. 2019 Sep;46(5):499-511. doi: 10.1017/cjn.2019.27. Epub 2019 Jul 16.

PMID:
31309917
15.

The Pictorial Fit-Frail Scale: Developing a Visual Scale to Assess Frailty.

Theou O, Andrew M, Ahip SS, Squires E, McGarrigle L, Blodgett JM, Goldstein J, Hominick K, Godin J, Hougan G, Armstrong JJ, Wallace L, Sazlina SG, Moorhouse P, Fay S, Visvanathan R, Rockwood K.

Can Geriatr J. 2019 Jun 30;22(2):64-74. doi: 10.5770/cgj.22.357. eCollection 2019 Jun.

16.

Bed rest and accelerated aging in relation to the musculoskeletal and cardiovascular systems and frailty biomarkers: A review.

Kehler DS, Theou O, Rockwood K.

Exp Gerontol. 2019 Sep;124:110643. doi: 10.1016/j.exger.2019.110643. Epub 2019 Jun 28. Review.

PMID:
31255732
17.

The Symptoms Targeted for Monitoring in a Web-Based Tracking Tool by Caregivers of People With Dementia and Agitation: Cross-Sectional Study.

Rockwood K, Sanon Aigbogun M, Stanley J, Wong H, Dunn T, Chapman CAT, Howlett SE, Miguelez M, McGarrigle L, Baker RA.

J Med Internet Res. 2019 Jun 28;21(6):e13360. doi: 10.2196/13360.

18.

Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018.

Muscedere J, Kim PM, Afilalo J, Balion C, Baracos VE, Bowdish D, Cesari M, Erusalimsky JD, Fülöp T, Heckman G, Howlett SE, Khadaroo RG, Kirkland JL, Rodriguez Mañas L, Marzetti E, Paré G, Raina P, Rockwood K, Sinclair A, Skappak C, Verschoor C, Walter S.

J Frailty Aging. 2019;8(3):106-116. doi: 10.14283/jfa.2019.12.

PMID:
31237310
19.

Frailty effects on non-demented cognitive trajectories are moderated by sex and Alzheimer's genetic risk.

Thibeau S, McDermott K, McFall GP, Rockwood K, Dixon RA.

Alzheimers Res Ther. 2019 Jun 21;11(1):55. doi: 10.1186/s13195-019-0509-9.

20.

Is the association between blood pressure and mortality in older adults different with frailty? A systematic review and meta-analysis.

Todd OM, Wilkinson C, Hale M, Wong NL, Hall M, Sheppard JP, McManus RJ, Rockwood K, Young J, Gale CP, Clegg A.

Age Ageing. 2019 Jun 5. pii: afz072. doi: 10.1093/ageing/afz072. [Epub ahead of print]

21.

Replacing Sedentary Time with Light or Moderate-Vigorous Physical Activity Across Levels of Frailty.

Godin J, Blodgett JM, Rockwood K, Theou O.

J Aging Phys Act. 2019 May 29:1-19. doi: 10.1123/japa.2018-0361. [Epub ahead of print]

PMID:
31141439
22.

Age-Related Whole-Brain Structural Changes in Relation to Cardiovascular Risks Across the Adult Age Spectrum.

Gu T, Fu C, Shen Z, Guo H, Zou M, Chen M, Rockwood K, Song X.

Front Aging Neurosci. 2019 Apr 24;11:85. doi: 10.3389/fnagi.2019.00085. eCollection 2019.

23.

Trends in site of death and health care utilization at the end of life: a population-based cohort study.

Hill AD, Stukel TA, Fu L, Scales DC, Laupacis A, Rubenfeld GD, Wunsch H, Downar J, Rockwood K, Heyland DK, Sinha SK, Zimmermann C, Gandhi S, Myers J, Ross HJ, Kozak JF, Berry S, Dev SP, La Delfa I, Fowler RA.

CMAJ Open. 2019 Apr 26;7(2):E306-E315. doi: 10.9778/cmajo.20180097. Print 2019 Apr-Jun.

24.

Effects of nonpharmacological interventions on functioning of people living with dementia at home: A systematic review of randomised controlled trials.

Scott I, Cooper C, Leverton M, Burton A, Beresford-Dent J, Rockwood K, Butler L, Rapaport P.

Int J Geriatr Psychiatry. 2019 Oct;34(10):1386-1402. doi: 10.1002/gps.5127. Epub 2019 May 21.

PMID:
31026082
25.

Age-related deficit accumulation and the diseases of ageing.

Rockwood K, Howlett SE.

Mech Ageing Dev. 2019 Jun;180:107-116. doi: 10.1016/j.mad.2019.04.005. Epub 2019 Apr 16. Review.

26.

Construction of a Frailty Index as a Novel Health Measure in Systemic Lupus Erythematosus.

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin P, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG.

J Rheumatol. 2019 Apr 15. pii: jrheum.181338. doi: 10.3899/jrheum.181338. [Epub ahead of print]

PMID:
30988130
27.

Exploring the responsiveness of goal attainment scaling in relation to number of goals set in a sample of hemophilia-A patients.

McGarrigle L, Roberts JC, Denne M, Rockwood K.

J Patient Rep Outcomes. 2019 Apr 1;3(1):20. doi: 10.1186/s41687-019-0110-9.

28.

Translating the Science of Frailty in Singapore: Results from the National Frailty Consensus Discussion.

Lim WS, Wong CH, Ding YY, Rockwood K, Lien C.

Ann Acad Med Singapore. 2019 Jan;48(1):25-31. No abstract available.

29.

Combining modifiable risk factors and risk of dementia: a systematic review and meta-analysis.

Peters R, Booth A, Rockwood K, Peters J, D'Este C, Anstey KJ.

BMJ Open. 2019 Jan 25;9(1):e022846. doi: 10.1136/bmjopen-2018-022846.

30.

Evaluating the Properties of a Frailty Index and Its Association With Mortality Risk Among Patients With Systemic Lupus Erythematosus.

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin P, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Steinsson K, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG.

Arthritis Rheumatol. 2019 Aug;71(8):1297-1307. doi: 10.1002/art.40859. Epub 2019 May 29.

PMID:
30771242
31.

Can a Prebiotic Formulation Reduce Frailty Levels in Older People?

Theou O, Jayanama K, Fernández-Garrido J, Buigues C, Pruimboom L, Hoogland AJ, Navarro-Martínez R, Rockwood K, Cauli O.

J Frailty Aging. 2019;8(1):48-52. doi: 10.14283/jfa.2018.39.

PMID:
30734832
32.

Characterizing the symptom of misplacing objects in people with dementia: findings from an online tracking tool.

McGarrigle L, Howlett SE, Wong H, Stanley J, Rockwood K.

Int Psychogeriatr. 2019 Nov;31(11):1635-1641. doi: 10.1017/S104161021800220X. Epub 2019 Jan 30.

PMID:
30698122
33.

Investigation of frailty as a moderator of the relationship between neuropathology and dementia in Alzheimer's disease: a cross-sectional analysis of data from the Rush Memory and Aging Project.

Wallace LMK, Theou O, Godin J, Andrew MK, Bennett DA, Rockwood K.

Lancet Neurol. 2019 Feb;18(2):177-184. doi: 10.1016/S1474-4422(18)30371-5. Erratum in: Lancet Neurol. 2019 Mar;18(3):e2.

PMID:
30663607
34.

Subjective memory complaints and incident dementia in a high risk older adult hypertensive population.

Peters R, Beckett N, Antikainen R, Rockwood K, Bulpitt CJ, Anstey KJ.

Age Ageing. 2019 Mar 1;48(2):253-259. doi: 10.1093/ageing/afy193.

PMID:
30615065
35.

Correction to: Frailty, nutrition-related parameters, and mortality across the adult age spectrum.

Jayanama K, Theou O, Blodgett JM, Cahill L, Rockwood K.

BMC Med. 2018 Dec 14;16(1):235. doi: 10.1186/s12916-018-1227-z.

36.

Fifteen years of progress in understanding frailty and health in aging.

Rockwood K, Howlett SE.

BMC Med. 2018 Nov 27;16(1):220. doi: 10.1186/s12916-018-1223-3.

37.

The impact of frailty and cognitive impairment on quality of life: employment and social context matter.

Godin J, Armstrong JJ, Wallace L, Rockwood K, Andrew MK.

Int Psychogeriatr. 2019 Jun;31(6):789-797. doi: 10.1017/S1041610218001710. Epub 2018 Nov 13.

PMID:
30421692
38.

Frailty, nutrition-related parameters, and mortality across the adult age spectrum.

Jayanama K, Theou O, Blodgett JM, Cahill L, Rockwood K.

BMC Med. 2018 Oct 26;16(1):188. doi: 10.1186/s12916-018-1176-6. Erratum in: BMC Med. 2018 Dec 14;16(1):235.

39.

Construct validation of a Frailty Index, an HIV Index and a Protective Index from a clinical HIV database.

Franconi I, Theou O, Wallace L, Malagoli A, Mussini C, Rockwood K, Guaraldi G.

PLoS One. 2018 Oct 17;13(10):e0201394. doi: 10.1371/journal.pone.0201394. eCollection 2018.

40.

Social and societal implications of frailty, including impact on Canadian healthcare systems.

Andrew MK, Dupuis-Blanchard S, Maxwell C, Giguere A, Keefe J, Rockwood K, St John P.

J Frailty Aging. 2018;7(4):217-223. doi: 10.14283/jfa.2018.30.

PMID:
30298169
41.

Validation of a Claims-Based Frailty Index Against Physical Performance and Adverse Health Outcomes in the Health and Retirement Study.

Kim DH, Glynn RJ, Avorn J, Lipsitz LA, Rockwood K, Pawar A, Schneeweiss S.

J Gerontol A Biol Sci Med Sci. 2019 Jul 12;74(8):1271-1276. doi: 10.1093/gerona/gly197.

42.

Relationship between frailty and Alzheimer's disease biomarkers: A scoping review.

Wallace L, Theou O, Rockwood K, Andrew MK.

Alzheimers Dement (Amst). 2018 May 30;10:394-401. doi: 10.1016/j.dadm.2018.05.002. eCollection 2018.

43.

Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort.

Peters R, Anstey KJ, Booth A, Beckett N, Warwick J, Antikainen R, Rockwood K, Peters J, Bulpitt CJ.

Eur Heart J. 2018 Sep 1;39(33):3135-3143. doi: 10.1093/eurheartj/ehy418.

44.

Older Adults in the Emergency Department with Frailty.

Theou O, Campbell S, Malone ML, Rockwood K.

Clin Geriatr Med. 2018 Aug;34(3):369-386. doi: 10.1016/j.cger.2018.04.003. Review.

PMID:
30031422
45.

Frailty, Hospitalization, and Mortality in Residential Aged Care.

Theou O, Sluggett JK, Bell JS, Lalic S, Cooper T, Robson L, Morley JE, Rockwood K, Visvanathan R.

J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1090-1096. doi: 10.1093/gerona/glx185.

PMID:
29985993
46.

Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies.

Mousa A, Savva GM, Mitnitski A, Rockwood K, Jagger C, Brayne C, Matthews FE.

Age Ageing. 2018 Sep 1;47(5):721-727. doi: 10.1093/ageing/afy077.

47.

What do we know about frailty in the acute care setting? A scoping review.

Theou O, Squires E, Mallery K, Lee JS, Fay S, Goldstein J, Armstrong JJ, Rockwood K.

BMC Geriatr. 2018 Jun 11;18(1):139. doi: 10.1186/s12877-018-0823-2. Review.

48.

Tracking changes in frailty throughout later life: results from a 17-year longitudinal study in the Netherlands.

Hoogendijk EO, Rockwood K, Theou O, Armstrong JJ, Onwuteaka-Philipsen BD, Deeg DJH, Huisman M.

Age Ageing. 2018 Sep 1;47(5):727-733. doi: 10.1093/ageing/afy081.

PMID:
29788032
49.

What proportion of older adults in hospital are frail?

Searle SD, Rockwood K.

Lancet. 2018 May 5;391(10132):1751-1752. doi: 10.1016/S0140-6736(18)30907-3. Epub 2018 Apr 26. No abstract available.

50.

Goal Attainment Scaling for haemophilia (GAS-Hēm): testing the feasibility of a new patient-centric outcome measure in people with haemophilia.

Roberts JC, Lattimore S, Recht M, Jackson S, Gue D, Squire S, Robinson KS, Price V, Denne M, Richardson S, Rockwood K.

Haemophilia. 2018 Jul;24(4):e199-e206. doi: 10.1111/hae.13454. Epub 2018 Apr 6.

PMID:
29626387

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