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Items: 1 to 50 of 514

1.

Evaluating the properties of a frailty index and its association with mortality risk among patients with systemic lupus erythematosus.

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin P, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Steinsson K, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG.

Arthritis Rheumatol. 2019 Feb 16. doi: 10.1002/art.40859. [Epub ahead of print]

PMID:
30771242
2.

Can a Prebiotic Formulation Reduce Frailty Levels in Older People?

Theou O, Jayanama K, Fernández-Garrido J, Buigues C, Pruimboom L, Hoogland AJ, Navarro-Martínez R, Rockwood K, Cauli O.

J Frailty Aging. 2019;8(1):48-52. doi: 10.14283/jfa.2018.39.

PMID:
30734832
3.

Characterizing the symptom of misplacing objects in people with dementia: findings from an online tracking tool.

McGarrigle L, Howlett SE, Wong H, Stanley J, Rockwood K.

Int Psychogeriatr. 2019 Jan 30:1-7. doi: 10.1017/S104161021800220X. [Epub ahead of print]

PMID:
30698122
4.

Investigation of frailty as a moderator of the relationship between neuropathology and dementia in Alzheimer's disease: a cross-sectional analysis of data from the Rush Memory and Aging Project.

Wallace LMK, Theou O, Godin J, Andrew MK, Bennett DA, Rockwood K.

Lancet Neurol. 2019 Feb;18(2):177-184. doi: 10.1016/S1474-4422(18)30371-5.

PMID:
30663607
5.

Subjective memory complaints and incident dementia in a high risk older adult hypertensive population.

Peters R, Beckett N, Antikainen R, Rockwood K, Bulpitt CJ, Anstey KJ.

Age Ageing. 2019 Jan 7. doi: 10.1093/ageing/afy193. [Epub ahead of print]

PMID:
30615065
6.

Correction to: Frailty, nutrition-related parameters, and mortality across the adult age spectrum.

Jayanama K, Theou O, Blodgett JM, Cahill L, Rockwood K.

BMC Med. 2018 Dec 14;16(1):235. doi: 10.1186/s12916-018-1227-z.

7.

Fifteen years of progress in understanding frailty and health in aging.

Rockwood K, Howlett SE.

BMC Med. 2018 Nov 27;16(1):220. doi: 10.1186/s12916-018-1223-3.

8.

The impact of frailty and cognitive impairment on quality of life: employment and social context matter.

Godin J, Armstrong JJ, Wallace L, Rockwood K, Andrew MK.

Int Psychogeriatr. 2018 Nov 13:1-9. doi: 10.1017/S1041610218001710. [Epub ahead of print]

PMID:
30421692
9.

Frailty, nutrition-related parameters, and mortality across the adult age spectrum.

Jayanama K, Theou O, Blodgett JM, Cahill L, Rockwood K.

BMC Med. 2018 Oct 26;16(1):188. doi: 10.1186/s12916-018-1176-6. Erratum in: BMC Med. 2018 Dec 14;16(1):235.

10.

Construct validation of a Frailty Index, an HIV Index and a Protective Index from a clinical HIV database.

Franconi I, Theou O, Wallace L, Malagoli A, Mussini C, Rockwood K, Guaraldi G.

PLoS One. 2018 Oct 17;13(10):e0201394. doi: 10.1371/journal.pone.0201394. eCollection 2018.

11.

Social and societal implications of frailty, including impact on Canadian healthcare systems.

Andrew MK, Dupuis-Blanchard S, Maxwell C, Giguere A, Keefe J, Rockwood K, St John P.

J Frailty Aging. 2018;7(4):217-223. doi: 10.14283/jfa.2018.30.

PMID:
30298169
12.

Validation of a Claims-Based Frailty Index Against Physical Performance and Adverse Health Outcomes in the Health and Retirement Study.

Kim DH, Glynn RJ, Avorn J, Lipsitz LA, Rockwood K, Pawar A, Schneeweiss S.

J Gerontol A Biol Sci Med Sci. 2018 Aug 27. doi: 10.1093/gerona/gly197. [Epub ahead of print]

PMID:
30165612
13.

Relationship between frailty and Alzheimer's disease biomarkers: A scoping review.

Wallace L, Theou O, Rockwood K, Andrew MK.

Alzheimers Dement (Amst). 2018 May 30;10:394-401. doi: 10.1016/j.dadm.2018.05.002. eCollection 2018.

14.

Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort.

Peters R, Anstey KJ, Booth A, Beckett N, Warwick J, Antikainen R, Rockwood K, Peters J, Bulpitt CJ.

Eur Heart J. 2018 Sep 1;39(33):3135-3143. doi: 10.1093/eurheartj/ehy418.

PMID:
30052878
15.

Older Adults in the Emergency Department with Frailty.

Theou O, Campbell S, Malone ML, Rockwood K.

Clin Geriatr Med. 2018 Aug;34(3):369-386. doi: 10.1016/j.cger.2018.04.003. Review.

PMID:
30031422
16.

Frailty, Hospitalization, and Mortality in Residential Aged Care.

Theou O, Sluggett JK, Bell JS, Lalic S, Cooper T, Robson L, Morley JE, Rockwood K, Visvanathan R.

J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1090-1096. doi: 10.1093/gerona/glx185.

PMID:
29985993
17.

Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies.

Mousa A, Savva GM, Mitnitski A, Rockwood K, Jagger C, Brayne C, Matthews FE.

Age Ageing. 2018 Sep 1;47(5):721-727. doi: 10.1093/ageing/afy077.

18.

What do we know about frailty in the acute care setting? A scoping review.

Theou O, Squires E, Mallery K, Lee JS, Fay S, Goldstein J, Armstrong JJ, Rockwood K.

BMC Geriatr. 2018 Jun 11;18(1):139. doi: 10.1186/s12877-018-0823-2.

19.

Tracking changes in frailty throughout later life: results from a 17-year longitudinal study in the Netherlands.

Hoogendijk EO, Rockwood K, Theou O, Armstrong JJ, Onwuteaka-Philipsen BD, Deeg DJH, Huisman M.

Age Ageing. 2018 Sep 1;47(5):727-733. doi: 10.1093/ageing/afy081.

PMID:
29788032
20.

What proportion of older adults in hospital are frail?

Searle SD, Rockwood K.

Lancet. 2018 May 5;391(10132):1751-1752. doi: 10.1016/S0140-6736(18)30907-3. Epub 2018 Apr 26. No abstract available.

21.

Goal Attainment Scaling for haemophilia (GAS-Hēm): testing the feasibility of a new patient-centric outcome measure in people with haemophilia.

Roberts JC, Lattimore S, Recht M, Jackson S, Gue D, Squire S, Robinson KS, Price V, Denne M, Richardson S, Rockwood K.

Haemophilia. 2018 Jul;24(4):e199-e206. doi: 10.1111/hae.13454. Epub 2018 Apr 6.

PMID:
29626387
22.

Assessing frailty in the intensive care unit: A reliability and validity study.

Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group.

J Crit Care. 2018 Jun;45:197-203. doi: 10.1016/j.jcrc.2018.02.004. Epub 2018 Feb 8.

PMID:
29574340
23.

Evidence for Cholinergic Dysfunction in Autosomal Dominant Kufs Disease.

Jarrett P, Easton A, Rockwood K, Dyack S, McCollum A, Siu V, Mirsattari SM, Massot-Tarrús A, Beis MJ, D'Souza N, Darvesh S.

Can J Neurol Sci. 2018 Mar;45(2):150-157. doi: 10.1017/cjn.2017.261.

PMID:
29506599
24.

Osteoporotic fractures and obesity affect frailty progression: a longitudinal analysis of the Canadian multicentre osteoporosis study.

Gajic-Veljanoski O, Papaioannou A, Kennedy C, Ioannidis G, Berger C, Wong AKO, Rockwood K, Kirkland S, Raina P, Thabane L, Adachi JD; CaMos Research Group.

BMC Geriatr. 2018 Jan 5;18(1):4. doi: 10.1186/s12877-017-0692-0.

25.

Measuring Frailty in Medicare Data: Development and Validation of a Claims-Based Frailty Index.

Kim DH, Schneeweiss S, Glynn RJ, Lipsitz LA, Rockwood K, Avorn J.

J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):980-987. doi: 10.1093/gerona/glx229.

PMID:
29244057
26.

Individualizing the care of older heart failure patients.

Heckman GA, McKelvie RS, Rockwood K.

Curr Opin Cardiol. 2018 Mar;33(2):208-216. doi: 10.1097/HCO.0000000000000489.

PMID:
29206692
27.

Delirium, Frailty, and Mortality: Interactions in a Prospective Study of Hospitalized Older People.

Dani M, Owen LH, Jackson TA, Rockwood K, Sampson EL, Davis D.

J Gerontol A Biol Sci Med Sci. 2018 Mar 2;73(3):415-418. doi: 10.1093/gerona/glx214.

28.

New horizons in multimorbidity in older adults.

Yarnall AJ, Sayer AA, Clegg A, Rockwood K, Parker S, Hindle JV.

Age Ageing. 2017 Nov 1;46(6):882-888. doi: 10.1093/ageing/afx150. Review.

29.

Reversing Frailty Levels in Primary Care Using the CARES Model.

Theou O, Park GH, Garm A, Song X, Clarke B, Rockwood K.

Can Geriatr J. 2017 Sep 28;20(3):105-111. doi: 10.5770/cgj.20.274. eCollection 2017 Sep.

30.

Predictors of transitions in frailty severity and mortality among people aging with HIV.

Brothers TD, Kirkland S, Theou O, Zona S, Malagoli A, Wallace LMK, Stentarelli C, Mussini C, Falutz J, Guaraldi G, Rockwood K.

PLoS One. 2017 Oct 5;12(10):e0185352. doi: 10.1371/journal.pone.0185352. eCollection 2017.

31.

A frailty index from common clinical and laboratory tests predicts increased risk of death across the life course.

Blodgett JM, Theou O, Howlett SE, Rockwood K.

Geroscience. 2017 Aug;39(4):447-455. doi: 10.1007/s11357-017-9993-7. Epub 2017 Sep 2.

32.

MRI assessment of whole-brain structural changes in aging.

Guo H, Siu W, D'Arcy RC, Black SE, Grajauskas LA, Singh S, Zhang Y, Rockwood K, Song X.

Clin Interv Aging. 2017 Aug 9;12:1251-1270. doi: 10.2147/CIA.S139515. eCollection 2017.

33.

Unifying aging and frailty through complex dynamical networks.

Rutenberg AD, Mitnitski AB, Farrell SG, Rockwood K.

Exp Gerontol. 2018 Jul 1;107:126-129. doi: 10.1016/j.exger.2017.08.027. Epub 2017 Aug 25. Review.

PMID:
28847723
34.

Association between sedentary time and mortality across levels of frailty.

Theou O, Blodgett JM, Godin J, Rockwood K.

CMAJ. 2017 Aug 21;189(33):E1056-E1064. doi: 10.1503/cmaj.161034.

35.

Correlates of frailty phenotype and frailty index and their associations with clinical outcomes.

Guaraldi G, Malagoli A, Theou O, Brothers TD, Wallace L, Torelli R, Mussini C, Sartini S, Kirkland SA, Rockwood K.

HIV Med. 2017 Nov;18(10):764-771. doi: 10.1111/hiv.12527. Epub 2017 Jul 24.

PMID:
28737297
36.

Dementia prevention, intervention, and care.

Livingston G, Sommerlad A, Orgeta V, Costafreda SG, Huntley J, Ames D, Ballard C, Banerjee S, Burns A, Cohen-Mansfield J, Cooper C, Fox N, Gitlin LN, Howard R, Kales HC, Larson EB, Ritchie K, Rockwood K, Sampson EL, Samus Q, Schneider LS, Selbæk G, Teri L, Mukadam N.

Lancet. 2017 Dec 16;390(10113):2673-2734. doi: 10.1016/S0140-6736(17)31363-6. Epub 2017 Jul 20. Review. No abstract available.

PMID:
28735855
37.

The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis.

Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, Sibley S, Rockwood K.

Intensive Care Med. 2017 Aug;43(8):1105-1122. doi: 10.1007/s00134-017-4867-0. Epub 2017 Jul 4. Review.

38.

The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty.

Dent E, Lien C, Lim WS, Wong WC, Wong CH, Ng TP, Woo J, Dong B, de la Vega S, Hua Poi PJ, Kamaruzzaman SBB, Won C, Chen LK, Rockwood K, Arai H, Rodriguez-Mañas L, Cao L, Cesari M, Chan P, Leung E, Landi F, Fried LP, Morley JE, Vellas B, Flicker L.

J Am Med Dir Assoc. 2017 Jul 1;18(7):564-575. doi: 10.1016/j.jamda.2017.04.018. Erratum in: J Am Med Dir Assoc. 2018 Jan;19(1):94.

PMID:
28648901
39.

Frailty status at admission to hospital predicts multiple adverse outcomes.

Hubbard RE, Peel NM, Samanta M, Gray LC, Mitnitski A, Rockwood K.

Age Ageing. 2017 Sep 1;46(5):801-806. doi: 10.1093/ageing/afx081.

PMID:
28531254
40.

4-1BB-Enhanced Expansion of CD8+ TIL from Triple-Negative Breast Cancer Unveils Mutation-Specific CD8+ T Cells.

Harao M, Forget MA, Roszik J, Gao H, Babiera GV, Krishnamurthy S, Chacon JA, Li S, Mittendorf EA, DeSnyder SM, Rockwood KF, Bernatchez C, Ueno NT, Radvanyi LG, Vence L, Haymaker C, Reuben JM.

Cancer Immunol Res. 2017 Jun;5(6):439-445. doi: 10.1158/2326-6066.CIR-16-0364. Epub 2017 May 4.

41.

Pharmacokinetic and pharmacodynamic alterations in older people with dementia.

Reeve E, Trenaman SC, Rockwood K, Hilmer SN.

Expert Opin Drug Metab Toxicol. 2017 Jun;13(6):651-668. doi: 10.1080/17425255.2017.1325873. Epub 2017 May 10. Review.

PMID:
28460576
42.

Integrating Frailty Research into the Medical Specialties-Report from a U13 Conference.

Walston J, Robinson TN, Zieman S, McFarland F, Carpenter CR, Althoff KN, Andrew MK, Blaum CS, Brown PJ, Buta B, Ely EW, Ferrucci L, High KP, Kritchevsky SB, Rockwood K, Schmader KE, Sierra F, Sink KM, Varadhan R, Hurria A.

J Am Geriatr Soc. 2017 Oct;65(10):2134-2139. doi: 10.1111/jgs.14902. Epub 2017 Apr 19.

43.

Geriatric-HIV Medicine Is Born.

Guaraldi G, Rockwood K.

Clin Infect Dis. 2017 Aug 1;65(3):507-509. doi: 10.1093/cid/cix316. No abstract available.

PMID:
28387817
44.

Dynamics of Frailty and Cognition After Age 50: Why It Matters that Cognitive Decline is Mostly Seen in Old Age.

Godin J, Armstrong JJ, Rockwood K, Andrew MK.

J Alzheimers Dis. 2017;58(1):231-242. doi: 10.3233/JAD-161280.

PMID:
28387672
45.

Clinical meaningfulness of Alzheimer's Disease Assessment Scale-Cognitive subscale change in relation to goal attainment in patients on cholinesterase inhibitors.

Rockwood K, Howlett SE, Hoffman D, Schindler R, Mitnitski A.

Alzheimers Dement. 2017 Oct;13(10):1098-1106. doi: 10.1016/j.jalz.2017.02.005. Epub 2017 Mar 21.

PMID:
28341540
46.

China's oldest-old-prospects for good health in late life.

Theou O, Rockwood K.

Lancet. 2017 Apr 22;389(10079):1584-1586. doi: 10.1016/S0140-6736(17)30699-2. Epub 2017 Mar 10. No abstract available.

PMID:
28285815
47.

The association between frailty, the metabolic syndrome, and mortality over the lifespan.

Kane AE, Gregson E, Theou O, Rockwood K, Howlett SE.

Geroscience. 2017 Apr;39(2):221-229. doi: 10.1007/s11357-017-9967-9. Epub 2017 Mar 9.

48.

Exploration of verbal repetition in people with dementia using an online symptom-tracking tool.

Reeve E, Molin P, Hui A, Rockwood K.

Int Psychogeriatr. 2017 Jun;29(6):959-966. doi: 10.1017/S1041610216002180. Epub 2017 Mar 9.

49.

Aging, frailty and complex networks.

Mitnitski AB, Rutenberg AD, Farrell S, Rockwood K.

Biogerontology. 2017 Aug;18(4):433-446. doi: 10.1007/s10522-017-9684-x. Epub 2017 Mar 2. Review.

PMID:
28255823
50.

A Frailty Index Based On Deficit Accumulation Quantifies Mortality Risk in Humans and in Mice.

Rockwood K, Blodgett JM, Theou O, Sun MH, Feridooni HA, Mitnitski A, Rose RA, Godin J, Gregson E, Howlett SE.

Sci Rep. 2017 Feb 21;7:43068. doi: 10.1038/srep43068.

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