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Items: 17

1.

Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities.

Rock BM, Foti R.

Drug Metab Dispos. 2019 Aug 9. pii: dmd.119.088708. doi: 10.1124/dmd.119.088708. [Epub ahead of print]

2.

Plasma and liver protein binding of GalNAc conjugated siRNA.

Humphreys SC, Thayer MB, Lade JM, Wu B, Sham K, Basiri B, Hao Y, Huang X, Smith R, Rock BM.

Drug Metab Dispos. 2019 May 16. pii: dmd.119.086967. doi: 10.1124/dmd.119.086967. [Epub ahead of print]

3.

Application of Locked Nucleic Acid Oligonucleotides for siRNA Preclinical Bioanalytics.

Thayer MB, Lade JM, Doherty D, Xie F, Basiri B, Barnaby OS, Bala NS, Rock BM.

Sci Rep. 2019 Mar 5;9(1):3566. doi: 10.1038/s41598-019-40187-4.

4.

Quantification of siRNA-Antibody Conjugates in Biological Matrices by Triplex-Forming Oligonucleotide ELISA.

Humphreys SC, Thayer MB, Campuzano IDG, Netirojjanakul C, Rock BM.

Nucleic Acid Ther. 2019 Jun;29(3):161-166. doi: 10.1089/nat.2018.0770. Epub 2019 Mar 12.

PMID:
30801231
5.

Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study therapeutic protein stability in vivo.

Han M, Pearson JT, Wang Y, Winters D, Soto M, Rock DA, Rock BM.

Anal Biochem. 2017 Dec 15;539:118-126. doi: 10.1016/j.ab.2017.10.005. Epub 2017 Oct 10.

PMID:
29029979
6.

SRM-based measurements of proprotein convertase subtilisin/kexin type 9 and lipoprotein(a) kinetics in nonhuman primate serum.

Xie F, Emery MG, Gibbs JP, Rock DA, Rock BM.

Bioanalysis. 2016 Dec;8(24):2551-2563.

PMID:
27884075
7.

Altering Antibody-Drug Conjugate Binding to the Neonatal Fc Receptor Impacts Efficacy and Tolerability.

Hamblett KJ, Le T, Rock BM, Rock DA, Siu S, Huard JN, Conner KP, Milburn RR, O'Neill JW, Tometsko ME, Fanslow WC.

Mol Pharm. 2016 Jul 5;13(7):2387-96. doi: 10.1021/acs.molpharmaceut.6b00153. Epub 2016 Jun 13.

PMID:
27248573
8.

Intact mass analysis of monoclonal antibodies by capillary electrophoresis-Mass spectrometry.

Han M, Rock BM, Pearson JT, Rock DA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:24-32. doi: 10.1016/j.jchromb.2015.12.045. Epub 2015 Dec 28.

PMID:
26751590
9.

SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm.

Hamblett KJ, Jacob AP, Gurgel JL, Tometsko ME, Rock BM, Patel SK, Milburn RR, Siu S, Ragan SP, Rock DA, Borths CJ, O'Neill JW, Chang WS, Weidner MF, Bio MM, Quon KC, Fanslow WC.

Cancer Res. 2015 Dec 15;75(24):5329-40. doi: 10.1158/0008-5472.CAN-15-1610. Epub 2015 Dec 2.

10.

Intracellular Catabolism of an Antibody Drug Conjugate with a Noncleavable Linker.

Rock BM, Tometsko ME, Patel SK, Hamblett KJ, Fanslow WC, Rock DA.

Drug Metab Dispos. 2015 Sep;43(9):1341-4. doi: 10.1124/dmd.115.064253. Epub 2015 Jun 22.

PMID:
26101225
11.

Characterization of ritonavir-mediated inactivation of cytochrome P450 3A4.

Rock BM, Hengel SM, Rock DA, Wienkers LC, Kunze KL.

Mol Pharmacol. 2014 Dec;86(6):665-74. doi: 10.1124/mol.114.094862. Epub 2014 Oct 1.

PMID:
25274602
12.

Evaluation of near infrared fluorescent labeling of monoclonal antibodies as a tool for tissue distribution.

Conner KP, Rock BM, Kwon GK, Balthasar JP, Abuqayyas L, Wienkers LC, Rock DA.

Drug Metab Dispos. 2014 Nov;42(11):1906-13. doi: 10.1124/dmd.114.060319. Epub 2014 Sep 10. Erratum in: Drug Metab Dispos. 2015 Jan;43(1):53.

PMID:
25209366
13.

Characterization of the active site properties of CYP4F12.

Eksterowicz J, Rock DA, Rock BM, Wienkers LC, Foti RS.

Drug Metab Dispos. 2014 Oct;42(10):1698-707. doi: 10.1124/dmd.114.059626. Epub 2014 Jul 29.

PMID:
25074871
14.
15.

Two Gq class G proteins are expressed in human keratinocytes.

Rock BM, Xin L, Wilcox JN.

J Invest Dermatol. 1997 Nov;109(5):645-9.

16.

Characterization of single-cell migration using a computer-aided fluorescence time-lapse videomicroscopy system.

Chon JH, Vizena AD, Rock BM, Chaikof EL.

Anal Biochem. 1997 Oct 15;252(2):246-54.

PMID:
9344410
17.

Pregnancy outcome following uterotubal implantation: a comparison of the reamer and sharp cornual wedge excision techniques.

Rock JA, Katayama KP, Martin EJ, Rock BM, Woodruff JD, Jones HW Jr.

Fertil Steril. 1979 Jun;31(6):634-40. No abstract available.

PMID:
446788

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