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Items: 1 to 50 of 106

1.

Interaction between maternally derived antibodies and heterogeneity in exposure combined to determine time-to-first Plasmodium falciparum infection in Kenyan infants.

Reynaldi A, Dent AE, Schlub TE, Ogolla S, Rochford R, Davenport MP.

Malar J. 2019 Jan 22;18(1):19. doi: 10.1186/s12936-019-2657-6.

2.

Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".

Brunschwig C, Lawrence N, Taylor D, Abay E, Njoroge M, Basarab GS, Le Manach C, Paquet T, Gonzàlez Cabrera D, Nchinda AT, de Kock C, Wiesner L, Denti P, Waterson D, Blasco B, Leroy D, Witty MJ, Donini C, Duffy J, Wittlin S, White KL, Charman SA, Jiménez-Díaz MB, Angulo-Barturen I, Herreros E, Gamo FJ, Rochford R, Mancama D, Coetzer TL, van der Watt ME, Reader J, Birkholtz LM, Marsh KC, Solapure SM, Burke JE, McPhail JA, Vanaerschot M, Fidock DA, Fish PV, Siegl P, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Silue KD, Street LJ, Chibale K.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01941-18. doi: 10.1128/AAC.01941-18. Print 2018 Nov. No abstract available.

3.

Differences in the Epstein-Barr virus gp350 IgA antibody response are associated with increased risk for co-infection with a second strain of EBV.

Smith NA, Baresel PC, Jackson CL, Ogolla S, Toko EN, Heit S, Piriou E, Sumba OP, Middeldorp JM, Colborn KL, Rochford R.

J Infect Dis. 2018 Oct 12. doi: 10.1093/infdis/jiy601. [Epub ahead of print]

PMID:
30312417
4.

Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice.

Coleman CB, Lang J, Sweet LA, Smith NA, Freed BM, Pan Z, Haverkos B, Pelanda R, Rochford R.

J Virol. 2018 Oct 12;92(21). pii: e00813-18. doi: 10.1128/JVI.00813-18. Print 2018 Nov 1.

PMID:
30089703
5.

Mast Cell Activation and KSHV Infection in Kaposi Sarcoma.

Ayers LW, Barbachano-Guerrero A, McAllister SC, Ritchie JA, Asiago-Reddy E, Bartlett LC, Cesarman E, Wang D, Rochford R, Martin JN, King CA.

Clin Cancer Res. 2018 Oct 15;24(20):5085-5097. doi: 10.1158/1078-0432.CCR-18-0873. Epub 2018 Jul 3.

PMID:
30084838
6.

A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection.

Bristol JA, Djavadian R, Albright ER, Coleman CB, Ohashi M, Hayes M, Romero-Masters JC, Barlow EA, Farrell PJ, Rochford R, Kalejta RF, Johannsen EC, Kenney SC.

PLoS Pathog. 2018 Jul 27;14(7):e1007179. doi: 10.1371/journal.ppat.1007179. eCollection 2018 Jul.

7.

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.

Brunschwig C, Lawrence N, Taylor D, Abay E, Njoroge M, Basarab GS, Le Manach C, Paquet T, Cabrera DG, Nchinda AT, de Kock C, Wiesner L, Denti P, Waterson D, Blasco B, Leroy D, Witty MJ, Donini C, Duffy J, Wittlin S, White KL, Charman SA, Jiménez-Díaz MB, Angulo-Barturen I, Herreros E, Gamo FJ, Rochford R, Mancama D, Coetzer TL, van der Watt ME, Reader J, Birkholtz LM, Marsh KC, Solapure SM, Burke JE, McPhail JA, Vanaerschot M, Fidock DA, Fish PV, Siegl P, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Silue KD, Street LJ, Chibale K.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00012-18. doi: 10.1128/AAC.00012-18. Print 2018 Sep. Erratum in: Antimicrob Agents Chemother. 2018 Oct 24;62(11):.

PMID:
29941635
8.

Determinants of Gammaherpesvirus Shedding in Saliva Among Ugandan Children and Their Mothers.

Newton R, Labo N, Wakeham K, Marshall V, Roshan R, Nalwoga A, Sebina I, Muhangi L, Webb EL, Miley W, Rochford R, Elliott AM, Whitby D.

J Infect Dis. 2018 Aug 14;218(6):892-900. doi: 10.1093/infdis/jiy262.

9.

Epstein-Barr Virus Type 2 Infects T Cells in Healthy Kenyan Children.

Coleman CB, Daud II, Ogolla SO, Ritchie JA, Smith NA, Sumba PO, Dent AE, Rochford R.

J Infect Dis. 2017 Sep 15;216(6):670-677. doi: 10.1093/infdis/jix363.

10.

Changes in Tonsil B Cell Phenotypes and EBV Receptor Expression in Children Under 5-Years-Old.

Wohlford EM, Baresel PC, Wilmore JR, Mortelliti AJ, Coleman CB, Rochford R.

Cytometry B Clin Cytom. 2018 Mar;94(2):291-301. doi: 10.1002/cyto.b.21589. Epub 2017 Nov 14.

PMID:
28885784
11.

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.

O'Neill PM, Amewu RK, Charman SA, Sabbani S, Gnädig NF, Straimer J, Fidock DA, Shore ER, Roberts NL, Wong MH, Hong WD, Pidathala C, Riley C, Murphy B, Aljayyoussi G, Gamo FJ, Sanz L, Rodrigues J, Cortes CG, Herreros E, Angulo-Barturén I, Jiménez-Díaz MB, Bazaga SF, Martínez-Martínez MS, Campo B, Sharma R, Ryan E, Shackleford DM, Campbell S, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Palmer MJ, Copple IM, Mercer AE, Ruecker A, Delves MJ, Sinden RE, Siegl P, Davies J, Rochford R, Kocken CHM, Zeeman AM, Nixon GL, Biagini GA, Ward SA.

Nat Commun. 2017 May 24;8:15159. doi: 10.1038/ncomms15159.

12.

Emerging insights on the pathogenesis and treatment of extranodal NK/T cell lymphomas (ENKTL).

Haverkos BM, Coleman C, Gru AA, Pan Z, Brammer J, Rochford R, Mishra A, Oakes CC, Baiocchi RA, Freud AG, Porcu P.

Discov Med. 2017 Mar;23(126):189-199. Review.

13.

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

Paquet T, Le Manach C, Cabrera DG, Younis Y, Henrich PP, Abraham TS, Lee MCS, Basak R, Ghidelli-Disse S, Lafuente-Monasterio MJ, Bantscheff M, Ruecker A, Blagborough AM, Zakutansky SE, Zeeman AM, White KL, Shackleford DM, Mannila J, Morizzi J, Scheurer C, Angulo-Barturen I, Martínez MS, Ferrer S, Sanz LM, Gamo FJ, Reader J, Botha M, Dechering KJ, Sauerwein RW, Tungtaeng A, Vanachayangkul P, Lim CS, Burrows J, Witty MJ, Marsh KC, Bodenreider C, Rochford R, Solapure SM, Jiménez-Díaz MB, Wittlin S, Charman SA, Donini C, Campo B, Birkholtz LM, Hanson KK, Drewes G, Kocken CHM, Delves MJ, Leroy D, Fidock DA, Waterson D, Street LJ, Chibale K.

Sci Transl Med. 2017 Apr 26;9(387). pii: eaad9735. doi: 10.1126/scitranslmed.aad9735.

14.

Household Dengue Prevention Interventions, Expenditures, and Barriers to Aedes aegypti Control in Machala, Ecuador.

Heydari N, Larsen DA, Neira M, Beltrán Ayala E, Fernandez P, Adrian J, Rochford R, Stewart-Ibarra AM.

Int J Environ Res Public Health. 2017 Feb 16;14(2). pii: E196. doi: 10.3390/ijerph14020196.

15.

Plasmodium chabaudi infection induces AID expression in transitional and marginal zone B cells.

Wilmore JR, Maue AC, Rochford R.

Immun Inflamm Dis. 2016 Nov 28;4(4):497-505. eCollection 2016 Dec.

16.

Maternal Vitamin D Status and Adverse Birth Outcomes in Children from Rural Western Kenya.

Toko EN, Sumba OP, Daud II, Ogolla S, Majiwa M, Krisher JT, Ouma C, Dent AE, Rochford R, Mehta S.

Nutrients. 2016 Dec 7;8(12). pii: E794.

17.

Successful malaria elimination in the Ecuador-Peru border region: epidemiology and lessons learned.

Krisher LK, Krisher J, Ambuludi M, Arichabala A, Beltrán-Ayala E, Navarrete P, Ordoñez T, Polhemus ME, Quintana F, Rochford R, Silva M, Bazo J, Stewart-Ibarra AM.

Malar J. 2016 Nov 28;15(1):573.

18.

Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases.

Haverkos BM, Pan Z, Gru AA, Freud AG, Rabinovitch R, Xu-Welliver M, Otto B, Barrionuevo C, Baiocchi RA, Rochford R, Porcu P.

Curr Hematol Malig Rep. 2016 Dec;11(6):514-527. doi: 10.1007/s11899-016-0355-9. Review.

19.

Modeling of EBV Infection and Antibody Responses in Kenyan Infants With Different Levels of Malaria Exposure Shows Maternal Antibody Decay is a Major Determinant of Early EBV Infection.

Reynaldi A, Schlub TE, Piriou E, Ogolla S, Sumba OP, Moormann AM, Rochford R, Davenport MP.

J Infect Dis. 2016 Nov 1;214(9):1390-1398. Epub 2016 Aug 28.

20.

Viral-associated malignancies in Africa: are viruses 'infectious traces' or 'dominant drivers'?

Rochford R, Korir A, Newton R.

Curr Opin Virol. 2016 Oct;20:28-33. doi: 10.1016/j.coviro.2016.08.002. Epub 2016 Aug 20. Review.

PMID:
27551983
21.

Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs.

Wickham KS, Baresel PC, Marcsisin SR, Sousa J, Vuong CT, Reichard GA, Campo B, Tekwani BL, Walker LA, Rochford R.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5906-13. doi: 10.1128/AAC.00600-16. Print 2016 Oct.

22.

Epstein-Barr virus infection of infants: implications of early age of infection on viral control and risk for Burkitt lymphoma.

Rochford R.

Bol Med Hosp Infant Mex. 2016 Jan - Feb;73(1):41-46. doi: 10.1016/j.bmhimx.2015.12.001. Epub 2016 Jan 6.

23.

Impact of Plasmodium falciparum Coinfection on Longitudinal Epstein-Barr Virus Kinetics in Kenyan Children.

Reynaldi A, Schlub TE, Chelimo K, Sumba PO, Piriou E, Ogolla S, Moormann AM, Rochford R, Davenport MP.

J Infect Dis. 2016 Mar 15;213(6):985-91. doi: 10.1093/infdis/jiv525. Epub 2015 Nov 3.

24.

The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment.

Gru AA, Haverkos BH, Freud AG, Hastings J, Nowacki NB, Barrionuevo C, Vigil CE, Rochford R, Natkunam Y, Baiocchi RA, Porcu P.

Curr Hematol Malig Rep. 2015 Dec;10(4):456-67. doi: 10.1007/s11899-015-0292-z. Review.

25.

Burkitt's Lymphoma.

Rochford R, Moormann AM.

Curr Top Microbiol Immunol. 2015;390(Pt 1):267-85. doi: 10.1007/978-3-319-22822-8_11. Review.

PMID:
26424650
26.

Reduced Transplacental Transfer of a Subset of Epstein-Barr Virus-Specific Antibodies to Neonates of Mothers Infected with Plasmodium falciparum Malaria during Pregnancy.

Ogolla S, Daud II, Asito AS, Sumba OP, Ouma C, Vulule J, Middeldorp JM, Dent AE, Mehta S, Rochford R.

Clin Vaccine Immunol. 2015 Nov;22(11):1197-205. doi: 10.1128/CVI.00270-15. Epub 2015 Sep 16.

27.

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.

Phillips MA, Lotharius J, Marsh K, White J, Dayan A, White KL, Njoroge JW, El Mazouni F, Lao Y, Kokkonda S, Tomchick DR, Deng X, Laird T, Bhatia SN, March S, Ng CL, Fidock DA, Wittlin S, Lafuente-Monasterio M, Benito FJ, Alonso LM, Martinez MS, Jimenez-Diaz MB, Bazaga SF, Angulo-Barturen I, Haselden JN, Louttit J, Cui Y, Sridhar A, Zeeman AM, Kocken C, Sauerwein R, Dechering K, Avery VM, Duffy S, Delves M, Sinden R, Ruecker A, Wickham KS, Rochford R, Gahagen J, Iyer L, Riccio E, Mirsalis J, Bathhurst I, Rueckle T, Ding X, Campo B, Leroy D, Rogers MJ, Rathod PK, Burrows JN, Charman SA.

Sci Transl Med. 2015 Jul 15;7(296):296ra111. doi: 10.1126/scitranslmed.aaa6645.

28.

Breast Milk as a Potential Source of Epstein-Barr Virus Transmission Among Infants Living in a Malaria-Endemic Region of Kenya.

Daud II, Coleman CB, Smith NA, Ogolla S, Simbiri K, Bukusi EA, Ng'ang'a ZW, Sumba PO, Vulule J, Ploutz-Snyder R, Dent AE, Rochford R.

J Infect Dis. 2015 Dec 1;212(11):1735-42. doi: 10.1093/infdis/jiv290. Epub 2015 May 17.

29.

Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population.

Simbiri KO, Smith NA, Otieno R, Wohlford EE, Daud II, Odada SP, Middleton F, Rochford R.

PLoS One. 2015 May 1;10(5):e0125420. doi: 10.1371/journal.pone.0125420. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0130229.

30.

HIV/AIDS and lipodystrophy: implications for clinical management in resource-limited settings.

Finkelstein JL, Gala P, Rochford R, Glesby MJ, Mehta S.

J Int AIDS Soc. 2015 Jan 15;18:19033. doi: 10.7448/IAS.18.1.19033. eCollection 2015. Review.

31.

Epstein-Barr virus type 2 latently infects T cells, inducing an atypical activation characterized by expression of lymphotactic cytokines.

Coleman CB, Wohlford EM, Smith NA, King CA, Ritchie JA, Baresel PC, Kimura H, Rochford R.

J Virol. 2015 Feb;89(4):2301-12. doi: 10.1128/JVI.03001-14. Epub 2014 Dec 10.

32.

AID expression in peripheral blood of children living in a malaria holoendemic region is associated with changes in B cell subsets and Epstein-Barr virus.

Wilmore JR, Asito AS, Wei C, Piriou E, Sumba PO, Sanz I, Rochford R.

Int J Cancer. 2015 Mar 15;136(6):1371-80. doi: 10.1002/ijc.29127. Epub 2014 Aug 19.

33.

Plasmodium falciparum infection is associated with Epstein-Barr virus reactivation in pregnant women living in malaria holoendemic area of Western Kenya.

Daud II, Ogolla S, Amolo AS, Namuyenga E, Simbiri K, Bukusi EA, Ng'ang'a ZW, Ploutz-Snyder R, Sumba PO, Dent A, Rochford R.

Matern Child Health J. 2015 Mar;19(3):606-14. doi: 10.1007/s10995-014-1546-4.

34.

Scalable preparation and differential pharmacologic and toxicologic profiles of primaquine enantiomers.

Nanayakkara NP, Tekwani BL, Herath HM, Sahu R, Gettayacamin M, Tungtaeng A, van Gessel Y, Baresel P, Wickham KS, Bartlett MS, Fronczek FR, Melendez V, Ohrt C, Reichard GA, McChesney JD, Rochford R, Walker LA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4737-44. doi: 10.1128/AAC.02674-13. Epub 2014 Jun 9.

35.

Developing clinical strength-of-evidence approach to define HIV-associated malignancies for cancer registration in Kenya.

Korir A, Mauti N, Moats P, Gurka MJ, Mutuma G, Metheny C, Mwamba PM, Oyiro PO, Fisher M, Ayers LW, Rochford R, Mwanda WO, Remick SC.

PLoS One. 2014 Jan 23;9(1):e85881. doi: 10.1371/journal.pone.0085881. eCollection 2014.

36.

Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.

Rochford R, Ohrt C, Baresel PC, Campo B, Sampath A, Magill AJ, Tekwani BL, Walker LA.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17486-91. doi: 10.1073/pnas.1310402110. Epub 2013 Oct 7.

37.

Acute Plasmodium chabaudi infection dampens humoral responses to a secondary T-dependent antigen but enhances responses to a secondary T-independent antigen.

Wilmore JR, Maue AC, Lefebvre JS, Haynes L, Rochford R.

J Immunol. 2013 Nov 1;191(9):4731-9. doi: 10.4049/jimmunol.1301450. Epub 2013 Sep 30.

38.

Identification of a novel variant of LMP-1 of EBV in patients with endemic Burkitt lymphoma in western Kenya.

Wohlford EM, Asito AS, Chelimo K, Sumba PO, Baresel PC, Oot RA, Moormann AM, Rochford R.

Infect Agent Cancer. 2013 Sep 9;8(1):34. doi: 10.1186/1750-9378-8-34.

39.

Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection.

Ayieko C, Maue AC, Jura WG, Noland GS, Ayodo G, Rochford R, John CC.

PLoS One. 2013 Jun 27;8(6):e67230. doi: 10.1371/journal.pone.0067230. Print 2013.

40.

MHV68 latency modulates the host immune response to influenza A virus.

Saito F, Ito T, Connett JM, Schaller MA, Carson WF 4th, Hogaboam CM, Rochford R, Kunkel SL.

Inflammation. 2013 Dec;36(6):1295-303. doi: 10.1007/s10753-013-9668-1.

41.

Burkitt's lymphoma.

Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S.

Lancet. 2012 Mar 31;379(9822):1234-44. doi: 10.1016/S0140-6736(11)61177-X. Epub 2012 Feb 13. Review.

42.

Early age at time of primary Epstein-Barr virus infection results in poorly controlled viral infection in infants from Western Kenya: clues to the etiology of endemic Burkitt lymphoma.

Piriou E, Asito AS, Sumba PO, Fiore N, Middeldorp JM, Moormann AM, Ploutz-Snyder R, Rochford R.

J Infect Dis. 2012 Mar 15;205(6):906-13. doi: 10.1093/infdis/jir872. Epub 2012 Feb 1.

43.

Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya.

Asito AS, Piriou E, Jura WG, Ouma C, Odada PS, Ogola S, Fiore N, Rochford R.

Malar J. 2011 Dec 13;10:362. doi: 10.1186/1475-2875-10-362.

44.

Blk haploinsufficiency impairs the development, but enhances the functional responses, of MZ B cells.

Samuelson EM, Laird RM, Maue AC, Rochford R, Hayes SM.

Immunol Cell Biol. 2012 Jul;90(6):620-9. doi: 10.1038/icb.2011.76. Epub 2011 Sep 6.

45.

Emerging infectious diseases as a global health threat. Introduction.

Endy TP, Rochford R, Yuen KY, Lei HY.

Exp Biol Med (Maywood). 2011 Aug;236(8):897-8. doi: 10.1258/ebm.2011.011i01. No abstract available.

PMID:
21821661
46.

In vivo activation of toll-like receptor-9 induces an age-dependent abortive lytic cycle reactivation of murine gammaherpesvirus-68.

Ptaschinski C, Wilmore J, Fiore N, Rochford R.

Viral Immunol. 2010 Dec;23(6):547-55. doi: 10.1089/vim.2010.0055.

47.

Microgeographic variations in Burkitt's lymphoma incidence correlate with differences in malnutrition, malaria and Epstein-Barr virus.

Sumba PO, Kabiru EW, Namuyenga E, Fiore N, Otieno RO, Moormann AM, Orago AS, Rosenbaum PF, Rochford R.

Br J Cancer. 2010 Nov 23;103(11):1736-41. doi: 10.1038/sj.bjc.6605947.

48.

Allele specificity of gamma interferon responses to the carboxyl-terminal region of Plasmodium falciparum merozoite surface protein 1 by Kenyan adults with naturally acquired immunity to malaria.

Spring MD, Chelimo K, Tisch DJ, Sumba PO, Rochford R, Long CA, Kazura JW, Moormann AM.

Infect Immun. 2010 Oct;78(10):4431-41. doi: 10.1128/IAI.00415-10. Epub 2010 Aug 9.

49.

Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study.

Asito AS, Piriou E, Odada PS, Fiore N, Middeldorp JM, Long C, Dutta S, Lanar DE, Jura WG, Ouma C, Otieno JA, Moormann AM, Rochford R.

Infect Agent Cancer. 2010 Jul 28;5:13. doi: 10.1186/1750-9378-5-13.

50.

Serological evidence for long-term Epstein-Barr virus reactivation in children living in a holoendemic malaria region of Kenya.

Piriou E, Kimmel R, Chelimo K, Middeldorp JM, Odada PS, Ploutz-Snyder R, Moormann AM, Rochford R.

J Med Virol. 2009 Jun;81(6):1088-93. doi: 10.1002/jmv.21485.

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