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Gait analysis with wearables predicts conversion to Parkinson's disease.

Del Din S, Elshehabi M, Galna B, Hobert M, Warmerdam E, Suenkel U, Brockmann K, Metzger F, Hansen C, Berg D, Rochester L, Maetzler W.

Ann Neurol. 2019 Jul 11. doi: 10.1002/ana.25548. [Epub ahead of print]


Clinical implications of early caudate dysfunction in Parkinson's disease.

Pasquini J, Durcan R, Wiblin L, Gersel Stokholm M, Rochester L, Brooks DJ, Burn D, Pavese N.

J Neurol Neurosurg Psychiatry. 2019 May 11. pii: jnnp-2018-320157. doi: 10.1136/jnnp-2018-320157. [Epub ahead of print]


Is every-day walking in older adults more analogous to dual-task walking or to usual walking? Elucidating the gaps between gait performance in the lab and during 24/7 monitoring.

Hillel I, Gazit E, Nieuwboer A, Avanzino L, Rochester L, Cereatti A, Croce UD, Rikkert MO, Bloem BR, Pelosin E, Del Din S, Ginis P, Giladi N, Mirelman A, Hausdorff JM.

Eur Rev Aging Phys Act. 2019 May 3;16:6. doi: 10.1186/s11556-019-0214-5. eCollection 2019.


Multicentre, randomised controlled trial of PDSAFE, a physiotherapist-delivered fall prevention programme for people with Parkinson's.

Chivers Seymour K, Pickering R, Rochester L, Roberts HC, Ballinger C, Hulbert S, Kunkel D, Marian IR, Fitton C, McIntosh E, Goodwin VA, Nieuwboer A, Lamb SE, Ashburn A.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):774-782. doi: 10.1136/jnnp-2018-319448. Epub 2019 Apr 3.


Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease.

Koychev I, Lawson J, Chessell T, Mackay C, Gunn R, Sahakian B, Rowe JB, Thomas AJ, Rochester L, Chan D, Tom B, Malhotra P, Ballard C, Chessell I, Ritchie CW, Raymont V, Leroi I, Lengyel I, Murray M, Thomas DL, Gallacher J, Lovestone S.

BMJ Open. 2019 Mar 23;9(3):e024498. doi: 10.1136/bmjopen-2018-024498.


A roadmap for implementation of patient-centered digital outcome measures in Parkinson's disease obtained using mobile health technologies.

Espay AJ, Hausdorff JM, Sánchez-Ferro Á, Klucken J, Merola A, Bonato P, Paul SS, Horak FB, Vizcarra JA, Mestre TA, Reilmann R, Nieuwboer A, Dorsey ER, Rochester L, Bloem BR, Maetzler W; Movement Disorder Society Task Force on Technology.

Mov Disord. 2019 May;34(5):657-663. doi: 10.1002/mds.27671. Epub 2019 Mar 22. Review.


Noninvasive vagus nerve stimulation to target gait impairment in Parkinson's disease.

Morris R, Yarnall AJ, Hunter H, Taylor JP, Baker MR, Rochester L.

Mov Disord. 2019 Jun;34(6):918-919. doi: 10.1002/mds.27664. Epub 2019 Mar 19. No abstract available.


The Role of Movement Analysis in Diagnosing and Monitoring Neurodegenerative Conditions: Insights from Gait and Postural Control.

Buckley C, Alcock L, McArdle R, Rehman RZU, Del Din S, Mazzà C, Yarnall AJ, Rochester L.

Brain Sci. 2019 Feb 6;9(2). pii: E34. doi: 10.3390/brainsci9020034. Review.


Associations between daily-living physical activity and laboratory-based assessments of motor severity in patients with falls and Parkinson's disease.

Galperin I, Hillel I, Del Din S, Bekkers EMJ, Nieuwboer A, Abbruzzese G, Avanzino L, Nieuwhof F, Bloem BR, Rochester L, Della Croce U, Cereatti A, Giladi N, Mirelman A, Hausdorff JM.

Parkinsonism Relat Disord. 2019 May;62:85-90. doi: 10.1016/j.parkreldis.2019.01.022. Epub 2019 Jan 29.


Mobilizing Parkinson's Disease: The Future of Exercise.

Ellis T, Rochester L.

J Parkinsons Dis. 2018;8(s1):S95-S100. doi: 10.3233/JPD-181489.


Postural Dynamics Are Associated With Cognitive Decline in Parkinson's Disease.

Pantall A, Suresparan P, Kapa L, Morris R, Yarnall A, Del Din S, Rochester L.

Front Neurol. 2018 Dec 5;9:1044. doi: 10.3389/fneur.2018.01044. eCollection 2018.


The neural correlates of discrete gait characteristics in ageing: A structured review.

Wilson J, Allcock L, Mc Ardle R, Taylor JP, Rochester L.

Neurosci Biobehav Rev. 2019 May;100:344-369. doi: 10.1016/j.neubiorev.2018.12.017. Epub 2018 Dec 13. Review.


Auditory Cueing for Gait Impairment in Persons With Parkinson Disease: A Pilot Study of Changes in Response With Disease Progression.

Lirani-Silva E, Lord S, Moat D, Rochester L, Morris R.

J Neurol Phys Ther. 2019 Jan;43(1):50-55. doi: 10.1097/NPT.0000000000000250.


Monitoring multiple cortical regions during walking in young and older adults: Dual-task response and comparison challenges.

Stuart S, Alcock L, Rochester L, Vitorio R, Pantall A.

Int J Psychophysiol. 2019 Jan;135:63-72. doi: 10.1016/j.ijpsycho.2018.11.006. Epub 2018 Nov 22.


Is it feasible to deliver a complex intervention to improve the outcome of falls in people with dementia? A protocol for the DIFRID feasibility study.

Allan LM, Wheatley A, Flynn E, Smith A, Fox C, Howel D, Barber R, Homer TM, Robinson L, Parry SW, Corner L, Connolly JA, Rochester L, Bamford C.

Pilot Feasibility Stud. 2018 Nov 10;4:170. doi: 10.1186/s40814-018-0364-7. eCollection 2018.


Reduced Gait Variability and Enhanced Brain Activity in Older Adults With Auditory Cues: A Functional Near-Infrared Spectroscopy Study.

Vitorio R, Stuart S, Gobbi LTB, Rochester L, Alcock L, Pantall A.

Neurorehabil Neural Repair. 2018 Nov;32(11):976-987. doi: 10.1177/1545968318805159.


Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer's Disease: A Pilot Study.

Koychev I, Galna B, Zetterberg H, Lawson J, Zamboni G, Ridha BH, Rowe JB, Thomas A, Howard R, Malhotra P, Ritchie C, Lovestone S, Rochester L.

J Alzheimers Dis. 2018;65(4):1377-1383. doi: 10.3233/JAD-180622.


Upper body accelerations as a biomarker of gait impairment in the early stages of Parkinson's disease.

Buckley C, Galna B, Rochester L, Mazzà C.

Gait Posture. 2019 Jun;71:289-295. doi: 10.1016/j.gaitpost.2018.06.166. Epub 2018 Jun 25.


"Staying safe" - a narrative review of falls prevention in people with Parkinson's - "PDSAFE".

Hulbert S, Rochester L, Nieuwboer A, Goodwin V, Fitton C, Chivers-Seymour K, Ashburn A.

Disabil Rehabil. 2018 May 18:1-10. doi: 10.1080/09638288.2018.1471167. [Epub ahead of print]


Estimation of spatio-temporal parameters of gait from magneto-inertial measurement units: multicenter validation among Parkinson, mildly cognitively impaired and healthy older adults.

Bertoli M, Cereatti A, Trojaniello D, Avanzino L, Pelosin E, Del Din S, Rochester L, Ginis P, Bekkers EMJ, Mirelman A, Hausdorff JM, Della Croce U.

Biomed Eng Online. 2018 May 9;17(1):58. doi: 10.1186/s12938-018-0488-2.


Longitudinal changes over thirty-six months in postural control dynamics and cognitive function in people with Parkinson's disease.

Pantall A, Del Din S, Rochester L.

Gait Posture. 2018 May;62:468-474. doi: 10.1016/j.gaitpost.2018.04.016. Epub 2018 Apr 13.


Do people with Parkinson's disease look at task relevant stimuli when walking? An exploration of eye movements.

Hunt D, Stuart S, Nell J, Hausdorff JM, Galna B, Rochester L, Alcock L.

Behav Brain Res. 2018 Aug 1;348:82-89. doi: 10.1016/j.bbr.2018.03.003. Epub 2018 Mar 17.


Gait & Posture Special Issue: Gait adaptations in response to obstacle type in fallers with Parkinson's disease.

Alcock L, Galna B, Hausdorff JM, Lord S, Rochester L.

Gait Posture. 2018 Mar;61:368-374. doi: 10.1016/j.gaitpost.2018.01.030. Epub 2018 Jan 31.


Saccade frequency response to visual cues during gait in Parkinson's disease: the selective role of attention.

Stuart S, Lord S, Galna B, Rochester L.

Eur J Neurosci. 2018 Apr;47(7):769-778. doi: 10.1111/ejn.13864. Epub 2018 Mar 1.


Step length determines minimum toe clearance in older adults and people with Parkinson's disease.

Alcock L, Galna B, Perkins R, Lord S, Rochester L.

J Biomech. 2018 Apr 11;71:30-36. doi: 10.1016/j.jbiomech.2017.12.002. Epub 2017 Dec 13.


Everyday Stepping Quantity and Quality Among Older Adult Fallers With and Without Mild Cognitive Impairment: Initial Evidence for New Motor Markers of Cognitive Deficits?

Hausdorff JM, Hillel I, Shustak S, Del Din S, Bekkers EMJ, Pelosin E, Nieuwhof F, Rochester L, Mirelman A.

J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1078-1082. doi: 10.1093/gerona/glx187.


Analysis of Free-Living Gait in Older Adults With and Without Parkinson's Disease and With and Without a History of Falls: Identifying Generic and Disease-Specific Characteristics.

Del Din S, Galna B, Godfrey A, Bekkers EMJ, Pelosin E, Nieuwhof F, Mirelman A, Hausdorff JM, Rochester L.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):500-506. doi: 10.1093/gerona/glx254.


The Pandora multi-algorithm approach to automated pattern recognition of cosmic-ray muon and neutrino events in the MicroBooNE detector.

Acciarri R, Adams C, An R, Anthony J, Asaadi J, Auger M, Bagby L, Balasubramanian S, Baller B, Barnes C, Barr G, Bass M, Bay F, Bishai M, Blake A, Bolton T, Camilleri L, Caratelli D, Carls B, Castillo Fernandez R, Cavanna F, Chen H, Church E, Cianci D, Cohen E, Collin GH, Conrad JM, Convery M, Crespo-Anadón JI, Del Tutto M, Devitt D, Dytman S, Eberly B, Ereditato A, Escudero Sanchez L, Esquivel J, Fadeeva AA, Fleming BT, Foreman W, Furmanski AP, Garcia-Gamez D, Garvey GT, Genty V, Goeldi D, Gollapinni S, Graf N, Gramellini E, Greenlee H, Grosso R, Guenette R, Hackenburg A, Hamilton P, Hen O, Hewes J, Hill C, Ho J, Horton-Smith G, Hourlier A, Huang EC, James C, Jan de Vries J, Jen CM, Jiang L, Johnson RA, Joshi J, Jostlein H, Kaleko D, Karagiorgi G, Ketchum W, Kirby B, Kirby M, Kobilarcik T, Kreslo I, Laube A, Li Y, Lister A, Littlejohn BR, Lockwitz S, Lorca D, Louis WC, Luethi M, Lundberg B, Luo X, Marchionni A, Mariani C, Marshall J, Martinez Caicedo DA, Meddage V, Miceli T, Mills GB, Moon J, Mooney M, Moore CD, Mousseau J, Murrells R, Naples D, Nienaber P, Nowak J, Palamara O, Paolone V, Papavassiliou V, Pate SF, Pavlovic Z, Piasetzky E, Porzio D, Pulliam G, Qian X, Raaf JL, Rafique A, Rochester L, Rudolf von Rohr C, Russell B, Schmitz DW, Schukraft A, Seligman W, Shaevitz MH, Sinclair J, Smith A, Snider EL, Soderberg M, Söldner-Rembold S, Soleti SR, Spentzouris P, Spitz J, St John J, Strauss T, Szelc AM, Tagg N, Terao K, Thomson M, Toups M, Tsai YT, Tufanli S, Usher T, Van De Pontseele W, Van de Water RG, Viren B, Weber M, Wickremasinghe DA, Wolbers S, Wongjirad T, Woodruff K, Yang T, Yates L, Zeller GP, Zennamo J, Zhang C.

Eur Phys J C Part Fields. 2018;78(1):82. doi: 10.1140/epjc/s10052-017-5481-6. Epub 2018 Jan 29.


Comprehensive measurement of stroke gait characteristics with a single accelerometer in the laboratory and community: a feasibility, validity and reliability study.

Moore SA, Hickey A, Lord S, Del Din S, Godfrey A, Rochester L.

J Neuroeng Rehabil. 2017 Dec 29;14(1):130. doi: 10.1186/s12984-017-0341-z.


Erratum: Author Correction: Using a smartphone-based self-management platform to support medication adherence and clinical consultation in Parkinson's disease.

Lakshminarayana R, Wang D, Burn D, Chaudhuri KR, Galtrey C, Guzman NV, Hellman B, James B, Pal S, Stamford J, Steiger M, Stott RW, Teo J, Barker RA, Wang E, Bloem BR, van der Eijk M, Rochester L, Williams A.

NPJ Parkinsons Dis. 2017 Nov 13;3:32. doi: 10.1038/s41531-017-0034-0. eCollection 2017.


Falls in Parkinson's disease: A complex and evolving picture.

Fasano A, Canning CG, Hausdorff JM, Lord S, Rochester L.

Mov Disord. 2017 Nov;32(11):1524-1536. doi: 10.1002/mds.27195. Epub 2017 Oct 25. Review.


What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review.

Mc Ardle R, Morris R, Wilson J, Galna B, Thomas AJ, Rochester L.

J Alzheimers Dis. 2017;60(4):1295-1312. doi: 10.3233/JAD-170541. Review.


fNIRS response during walking - Artefact or cortical activity? A systematic review.

Vitorio R, Stuart S, Rochester L, Alcock L, Pantall A.

Neurosci Biobehav Rev. 2017 Dec;83:160-172. doi: 10.1016/j.neubiorev.2017.10.002. Epub 2017 Oct 7. Review.


The Role of Vitamin D in Disease Progression in Early Parkinson's Disease.

Sleeman I, Aspray T, Lawson R, Coleman S, Duncan G, Khoo TK, Schoenmakers I, Rochester L, Burn D, Yarnall A.

J Parkinsons Dis. 2017;7(4):669-675. doi: 10.3233/JPD-171122.


Natural history of falls in an incident cohort of Parkinson's disease: early evolution, risk and protective features.

Lord S, Galna B, Yarnall AJ, Morris R, Coleman S, Burn D, Rochester L.

J Neurol. 2017 Nov;264(11):2268-2276. doi: 10.1007/s00415-017-8620-y. Epub 2017 Sep 25.


Validation of a Step Detection Algorithm during Straight Walking and Turning in Patients with Parkinson's Disease and Older Adults Using an Inertial Measurement Unit at the Lower Back.

Pham MH, Elshehabi M, Haertner L, Del Din S, Srulijes K, Heger T, Synofzik M, Hobert MA, Faber GS, Hansen C, Salkovic D, Ferreira JJ, Berg D, Sanchez-Ferro Á, van Dieën JH, Becker C, Rochester L, Schmidt G, Maetzler W.

Front Neurol. 2017 Sep 4;8:457. doi: 10.3389/fneur.2017.00457. eCollection 2017.


Fall-Prone Older People's Attitudes towards the Use of Virtual Reality Technology for Fall Prevention.

Dockx K, Alcock L, Bekkers E, Ginis P, Reelick M, Pelosin E, Lagravinese G, Hausdorff JM, Mirelman A, Rochester L, Nieuwboer A.

Gerontology. 2017;63(6):590-598. doi: 10.1159/000479085. Epub 2017 Aug 18.


PET Tau and Amyloid-β Burden in Mild Alzheimer's Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers.

Koychev I, Gunn RN, Firouzian A, Lawson J, Zamboni G, Ridha B, Sahakian BJ, Rowe JB, Thomas A, Rochester L, Ffytche D, Howard R, Zetterberg H, MacKay C, Lovestone S; Deep and Frequent Phenotyping study team (.

J Alzheimers Dis. 2017;60(1):283-293. doi: 10.3233/JAD-170129. Erratum in: J Alzheimers Dis. 2018;63(1):407.


Robot Assisted Training for the Upper Limb after Stroke (RATULS): study protocol for a randomised controlled trial.

Rodgers H, Shaw L, Bosomworth H, Aird L, Alvarado N, Andole S, Cohen DL, Dawson J, Eyre J, Finch T, Ford GA, Hislop J, Hogg S, Howel D, Hughes N, Krebs HI, Price C, Rochester L, Stamp E, Ternent L, Turner D, Vale L, Warburton E, van Wijck F, Wilkes S.

Trials. 2017 Jul 20;18(1):340. doi: 10.1186/s13063-017-2083-4.


Do you see what I see? Mobile eye-tracker contextual analysis and inter-rater reliability.

Stuart S, Hunt D, Nell J, Godfrey A, Hausdorff JM, Rochester L, Alcock L.

Med Biol Eng Comput. 2018 Feb;56(2):289-296. doi: 10.1007/s11517-017-1669-z. Epub 2017 Jul 15.


Poor Sleep Quality and Progression of Gait Impairment in an Incident Parkinson's Disease Cohort.

O'Dowd S, Galna B, Morris R, Lawson RA, McDonald C, Yarnall AJ, Burn DJ, Rochester L, Anderson KN.

J Parkinsons Dis. 2017;7(3):465-470. doi: 10.3233/JPD-161062.


Using a smartphone-based self-management platform to support medication adherence and clinical consultation in Parkinson's disease.

Lakshminarayana R, Wang D, Burn D, Chaudhuri KR, Galtrey C, Guzman NV, Hellman B, Ben James, Pal S, Stamford J, Steiger M, Stott RW, Teo J, Barker RA, Wang E, Bloem BR, van der Eijk M, Rochester L, Williams A.

NPJ Parkinsons Dis. 2017 Jan 9;3:2. doi: 10.1038/s41531-016-0003-z. eCollection 2017. Erratum in: NPJ Parkinsons Dis. 2017 Nov 13;3:32.


Longitudinal falls data in Parkinson's disease: feasibility of fall diaries and effect of attrition.

Hunter H, Rochester L, Morris R, Lord S.

Disabil Rehabil. 2018 Sep;40(19):2236-2241. doi: 10.1080/09638288.2017.1329357. Epub 2017 Jun 2.


Gait Rather Than Cognition Predicts Decline in Specific Cognitive Domains in Early Parkinson's Disease.

Morris R, Lord S, Lawson RA, Coleman S, Galna B, Duncan GW, Khoo TK, Yarnall AJ, Burn DJ, Rochester L.

J Gerontol A Biol Sci Med Sci. 2017 Nov 9;72(12):1656-1662. doi: 10.1093/gerona/glx071.


Direct and indirect effects of attention and visual function on gait impairment in Parkinson's disease: influence of task and turning.

Stuart S, Galna B, Delicato LS, Lord S, Rochester L.

Eur J Neurosci. 2017 Jul;46(1):1703-1716. doi: 10.1111/ejn.13589. Epub 2017 May 19.


Have we been overestimating fall rates in Parkinson's disease?

Lord S, Galna B, Yarnall AJ, Coleman S, Burn D, Rochester L.

Mov Disord. 2017 May;32(5):803-804. doi: 10.1002/mds.27009. Epub 2017 Apr 21. No abstract available.


Decrease in Aβ42 predicts dopa-resistant gait progression in early Parkinson disease.

Rochester L, Galna B, Lord S, Yarnall AJ, Morris R, Duncan G, Khoo TK, Mollenhauer B, Burn DJ.

Neurology. 2017 Apr 18;88(16):1501-1511. doi: 10.1212/WNL.0000000000003840. Epub 2017 Mar 22. Erratum in: Neurology. 2017 Jul 4;89(1):107.


Toward a low-cost gait analysis system for clinical and free-living assessment.

Ladha C, Del Din S, Nazarpour K, Hickey A, Morris R, Catt M, Rochester L, Godfrey A.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1874-1877. doi: 10.1109/EMBC.2016.7591086.


Towards holistic free-living assessment in Parkinson's disease: Unification of gait and fall algorithms with a single accelerometer.

Godfrey A, Bourke A, Del Din S, Morris R, Hickey A, Helbostad JL, Rochester L.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:651-654. doi: 10.1109/EMBC.2016.7590786.


Virtual reality for rehabilitation in Parkinson's disease.

Dockx K, Bekkers EM, Van den Bergh V, Ginis P, Rochester L, Hausdorff JM, Mirelman A, Nieuwboer A.

Cochrane Database Syst Rev. 2016 Dec 21;12:CD010760. doi: 10.1002/14651858.CD010760.pub2. Review.

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