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Items: 46

1.

Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation.

Regeenes R, Silva PN, Chang HH, Arany EJ, Shukalyuk AI, Audet J, Kilkenny DM, Rocheleau JV.

J Biol Chem. 2018 Nov 2;293(44):17218-17228. doi: 10.1074/jbc.RA118.003036. Epub 2018 Sep 14.

PMID:
30217817
2.

Isolation of Phenotypically Distinct Cancer Cells Using Nanoparticle-Mediated Sorting.

Green BJ, Kermanshah L, Labib M, Ahmed SU, Silva PN, Mahmoudian L, Chang IH, Mohamadi RM, Rocheleau JV, Kelley SO.

ACS Appl Mater Interfaces. 2017 Jun 21;9(24):20435-20443. doi: 10.1021/acsami.7b05253. Epub 2017 Jun 7.

PMID:
28548481
3.

Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action.

Filippi BM, Abraham MA, Silva PN, Rasti M, LaPierre MP, Bauer PV, Rocheleau JV, Lam TKT.

Cell Rep. 2017 Mar 7;18(10):2301-2309. doi: 10.1016/j.celrep.2017.02.035.

4.

Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis.

Chen YY, Silva PN, Syed AM, Sindhwani S, Rocheleau JV, Chan WC.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14915-14920. doi: 10.1073/pnas.1609569114. Epub 2016 Dec 12. Erratum in: Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E1036.

5.

Single-Molecule Analysis of the Supramolecular Organization of the M2 Muscarinic Receptor and the Gαi1 Protein.

Shivnaraine RV, Fernandes DD, Ji H, Li Y, Kelly B, Zhang Z, Han YR, Huang F, Sankar KS, Dubins DN, Rocheleau JV, Wells JW, Gradinaru CC.

J Am Chem Soc. 2016 Sep 14;138(36):11583-98. doi: 10.1021/jacs.6b04032. Epub 2016 Sep 2.

PMID:
27494760
6.

Highly efficient adenoviral transduction of pancreatic islets using a microfluidic device.

Silva PN, Atto Z, Regeenes R, Tufa U, Chen YY, Chan WC, Volchuk A, Kilkenny DM, Rocheleau JV.

Lab Chip. 2016 Aug 7;16(15):2921-34. doi: 10.1039/c6lc00345a. Epub 2016 Jul 5.

PMID:
27378588
7.

Allosteric modulation in monomers and oligomers of a G protein-coupled receptor.

Shivnaraine RV, Kelly B, Sankar KS, Redka DS, Han YR, Huang F, Elmslie G, Pinto D, Li Y, Rocheleau JV, Gradinaru CC, Ellis J, Wells JW.

Elife. 2016 May 6;5. pii: e11685. doi: 10.7554/eLife.11685.

8.

The FGF21 Receptor Signaling Complex: Klothoβ, FGFR1c, and Other Regulatory Interactions.

Kilkenny DM, Rocheleau JV.

Vitam Horm. 2016;101:17-58. doi: 10.1016/bs.vh.2016.02.008. Epub 2016 Mar 24. Review.

PMID:
27125737
9.

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology.

Sykes EA, Dai Q, Sarsons CD, Chen J, Rocheleau JV, Hwang DM, Zheng G, Cramb DT, Rinker KD, Chan WC.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1142-51. doi: 10.1073/pnas.1521265113. Epub 2016 Feb 16.

10.

Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis.

Nosak C, Silva PN, Sollazzo P, Moon KM, Odisho T, Foster LJ, Rocheleau JV, Volchuk A.

PLoS One. 2016 Feb 16;11(2):e0149177. doi: 10.1371/journal.pone.0149177. eCollection 2016.

11.

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).

Cameron WD, Bui CV, Hutchinson A, Loppnau P, Gräslund S, Rocheleau JV.

Nat Methods. 2016 Apr;13(4):352-8. doi: 10.1038/nmeth.3764. Epub 2016 Feb 15.

PMID:
26878383
12.

Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin.

Nirmalanandhan VS, Hurren R, Cameron WD, Gronda M, Shamas-Din A, You L, Minden MD, Rocheleau JV, Schimmer AD.

Haematologica. 2015 Oct;100(10):e406-8. doi: 10.3324/haematol.2015.129866. Epub 2015 Jul 16. No abstract available.

13.

LKB1 couples glucose metabolism to insulin secretion in mice.

Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA.

Diabetologia. 2015 Jul;58(7):1513-22. doi: 10.1007/s00125-015-3579-7. Epub 2015 Apr 16.

PMID:
25874445
14.

Retraction for Zhang et al., Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex.

Zhang Q, Wang SY, Fleuriel C, Dominique L, Rocheleau JV, Piston DW, Goodman RH.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E819. doi: 10.1073/pnas.1501052112. Epub 2015 Feb 2. No abstract available.

15.

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport.

Albanese A, Lam AK, Sykes EA, Rocheleau JV, Chan WC.

Nat Commun. 2013;4:2718. doi: 10.1038/ncomms3718.

16.

A microfluidic device designed to induce media flow throughout pancreatic islets while limiting shear-induced damage.

Silva PN, Green BJ, Altamentova SM, Rocheleau JV.

Lab Chip. 2013 Nov 21;13(22):4374-84. doi: 10.1039/c3lc50680k.

PMID:
24056576
17.

Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties.

Patel PC, Lee HS, Ming AY, Rath A, Deber CM, Yip CM, Rocheleau JV, Gray-Owen SD.

J Biol Chem. 2013 Oct 11;288(41):29654-69. doi: 10.1074/jbc.M113.504639. Epub 2013 Sep 4.

18.

Fibroblast growth factor receptor like-1 (FGFRL1) interacts with SHP-1 phosphatase at insulin secretory granules and induces beta-cell ERK1/2 protein activation.

Silva PN, Altamentova SM, Kilkenny DM, Rocheleau JV.

J Biol Chem. 2013 Jun 14;288(24):17859-70. doi: 10.1074/jbc.M112.440677. Epub 2013 May 2.

19.

Autofluorescence imaging of living pancreatic islets reveals fibroblast growth factor-21 (FGF21)-induced metabolism.

Sun MY, Yoo E, Green BJ, Altamentova SM, Kilkenny DM, Rocheleau JV.

Biophys J. 2012 Dec 5;103(11):2379-88. doi: 10.1016/j.bpj.2012.10.028.

20.

Quantitative imaging of electron transfer flavoprotein autofluorescence reveals the dynamics of lipid partitioning in living pancreatic islets.

Lam AK, Silva PN, Altamentova SM, Rocheleau JV.

Integr Biol (Camb). 2012 Aug;4(8):838-46. doi: 10.1039/c2ib20075a. Epub 2012 Jun 25.

PMID:
22733276
21.

Dynamics and Distribution of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex.

Ming AY, Yoo E, Vorontsov EN, Altamentova SM, Kilkenny DM, Rocheleau JV.

J Biol Chem. 2012 Jun 8;287(24):19997-20006. doi: 10.1074/jbc.M111.325670. Epub 2012 Apr 20.

22.

Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells.

Sankar KS, Green BJ, Crocker AR, Verity JE, Altamentova SM, Rocheleau JV.

PLoS One. 2011;6(9):e24904. doi: 10.1371/journal.pone.0024904. Epub 2011 Sep 22.

23.

Rapid extravasation and establishment of breast cancer micrometastases in the liver microenvironment.

Martin MD, Kremers GJ, Short KW, Rocheleau JV, Xu L, Piston DW, Matrisian LM, Gorden DL.

Mol Cancer Res. 2010 Oct;8(10):1319-27. doi: 10.1158/1541-7786.MCR-09-0551. Epub 2010 Aug 19.

24.

OASIS/CREB3L1 induces expression of genes involved in extracellular matrix production but not classical endoplasmic reticulum stress response genes in pancreatic beta-cells.

Vellanki RN, Zhang L, Guney MA, Rocheleau JV, Gannon M, Volchuk A.

Endocrinology. 2010 Sep;151(9):4146-57. doi: 10.1210/en.2010-0137. Epub 2010 Jul 28.

25.

Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics.

Easley CJ, Rocheleau JV, Head WS, Piston DW.

Anal Chem. 2009 Nov 1;81(21):9086-95. doi: 10.1021/ac9017692.

26.

Chapter 4: Combining microfluidics and quantitative fluorescence microscopy to examine pancreatic islet molecular physiology.

Rocheleau JV, Piston DW.

Methods Cell Biol. 2008;89:71-92. doi: 10.1016/S0091-679X(08)00604-3.

PMID:
19118673
27.

Two-photon excitation microscopy for the study of living cells and tissues.

Rocheleau JV, Piston DW.

Curr Protoc Cell Biol. 2003 Nov;Chapter 4:Unit 4.11. doi: 10.1002/0471143030.cb0411s20.

PMID:
18228433
28.
29.

Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex.

Zhang Q, Wang SY, Fleuriel C, Leprince D, Rocheleau JV, Piston DW, Goodman RH.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):829-33. Epub 2007 Jan 9. Retraction in: Zhang Q, Wang SY, Fleuriel C, Dominique L, Rocheleau JV, Piston DW, Goodman RH. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E819.

30.

Hyperinsulinism in mice with heterozygous loss of K(ATP) channels.

Remedi MS, Rocheleau JV, Tong A, Patton BL, McDaniel ML, Piston DW, Koster JC, Nichols CG.

Diabetologia. 2006 Oct;49(10):2368-78. Epub 2006 Aug 19.

PMID:
16924481
31.

Redox sensor CtBP mediates hypoxia-induced tumor cell migration.

Zhang Q, Wang SY, Nottke AC, Rocheleau JV, Piston DW, Goodman RH.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9029-33. Epub 2006 Jun 1.

32.

Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase.

Gunawardana SC, Rocheleau JV, Head WS, Piston DW.

Diabetes. 2006 Apr;55(4):1029-33.

33.

Critical role of gap junction coupled KATP channel activity for regulated insulin secretion.

Rocheleau JV, Remedi MS, Granada B, Head WS, Koster JC, Nichols CG, Piston DW.

PLoS Biol. 2006 Feb;4(2):e26. Epub 2006 Jan 17.

34.

Regulation of two insulin granule populations within the reserve pool by distinct calcium sources.

Hao M, Li X, Rizzo MA, Rocheleau JV, Dawant BM, Piston DW.

J Cell Sci. 2005 Dec 15;118(Pt 24):5873-84. Epub 2005 Nov 29.

35.

Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor.

Shiota C, Rocheleau JV, Shiota M, Piston DW, Magnuson MA.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E570-7. Epub 2005 Jun 7.

36.

NDRG1 is necessary for p53-dependent apoptosis.

Stein S, Thomas EK, Herzog B, Westfall MD, Rocheleau JV, Jackson RS 2nd, Wang M, Liang P.

J Biol Chem. 2004 Nov 19;279(47):48930-40. Epub 2004 Sep 17.

37.

Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets.

Rocheleau JV, Walker GM, Head WS, McGuinness OP, Piston DW.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12899-903. Epub 2004 Aug 18.

38.

Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH.

Gunawardana SC, Rocheleau JV, Head WS, Piston DW.

BMC Endocr Disord. 2004 Jun 11;4(1):1.

39.

Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.

Rocheleau JV, Head WS, Piston DW.

J Biol Chem. 2004 Jul 23;279(30):31780-7. Epub 2004 May 17.

40.

Fibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.

Byrd VM, Kilkenny DM, Dikov MM, Reich MB, Rocheleau JV, Armistead WJ, Thomas JW, Miller GG.

Immunol Cell Biol. 2003 Dec;81(6):440-50. Review.

PMID:
14636241
41.
42.
43.

c-Src regulation of fibroblast growth factor-induced proliferation in murine embryonic fibroblasts.

Kilkenny DM, Rocheleau JV, Price J, Reich MB, Miller GG.

J Biol Chem. 2003 May 9;278(19):17448-54. Epub 2003 Mar 5.

44.

Pancreatic islet beta-cells transiently metabolize pyruvate.

Rocheleau JV, Head WS, Nicholson WE, Powers AC, Piston DW.

J Biol Chem. 2002 Aug 23;277(34):30914-20. Epub 2002 Jun 17.

45.

The Sendai virus membrane fusion mechanism studied using image correlation spectroscopy.

Rocheleau JV, Petersen NO.

Eur J Biochem. 2001 May;268(10):2924-30.

46.

Sendai virus binds to a dispersed population of NBD-GD1a.

Rocheleau JV, Petersen NO.

Biosci Rep. 2000 Jun;20(3):139-55.

PMID:
11095114

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