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Electroencephalographic spectral power as a marker of cortical function and disease severity in girls with Rett syndrome.

Roche KJ, LeBlanc JJ, Levin AR, O'Leary HM, Baczewski LM, Nelson CA.

J Neurodev Disord. 2019 Jul 31;11(1):15. doi: 10.1186/s11689-019-9275-z.


SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation.

Kim ET, Roche KL, Kulej K, Spruce LA, Seeholzer SH, Coen DM, Diaz-Griffero F, Murphy EA, Weitzman MD.

Cell Rep. 2019 Jul 9;28(2):434-448.e6. doi: 10.1016/j.celrep.2019.06.027.


Effects of Family Demographics and the Passage of Time on Parents' Difficulty with Their Lesbian, Gay, or Bisexual Youth's Sexual Orientation.

Huebner DM, Roche KM, Rith KA.

Arch Sex Behav. 2019 Jul;48(5):1581-1588. doi: 10.1007/s10508-019-1430-9. Epub 2019 Jun 19.


Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo.

Lomash RM, Petralia RS, Holtzclaw LA, Tsuda MC, Wang YX, Badger JD 2nd, Cameron HA, Youle RJ, Roche KW.

J Biol Chem. 2019 Jul 26;294(30):11498-11512. doi: 10.1074/jbc.RA118.007245. Epub 2019 Jun 7.


PSD-95 binding dynamically regulates NLGN1 trafficking and function.

Jeong J, Pandey S, Li Y, Badger JD 2nd, Lu W, Roche KW.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):12035-12044. doi: 10.1073/pnas.1821775116. Epub 2019 May 28.


Effectiveness of home fire safety interventions. A systematic review and meta-analysis.

Senthilkumaran M, Nazari G, MacDermid JC, Roche K, Sopko K.

PLoS One. 2019 May 20;14(5):e0215724. doi: 10.1371/journal.pone.0215724. eCollection 2019.


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018 Jun;2(6):443-452. doi: 10.1038/s41551-018-0231-0. Epub 2018 Apr 23.


The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation.

Won S, Incontro S, Li Y, Nicoll RA, Roche KW.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8028-8037. doi: 10.1073/pnas.1900878116. Epub 2019 Apr 1.


Autonomy-related Parenting Processes and Adolescent Adjustment in Latinx Immigrant Families.

Roche KM, Lambert SF, White RMB, Calzada EJ, Little TD, Kuperminc GP, Schulenberg JE.

J Youth Adolesc. 2019 Jun;48(6):1161-1174. doi: 10.1007/s10964-019-01010-5. Epub 2019 Mar 7.


Monocytes Latently Infected with Human Cytomegalovirus Evade Neutrophil Killing.

Elder E, Krishna B, Williamson J, Aslam Y, Farahi N, Wood A, Romashova V, Roche K, Murphy E, Chilvers E, Lehner PJ, Sinclair J, Poole E.

iScience. 2019 Feb 22;12:13-26. doi: 10.1016/j.isci.2019.01.007. Epub 2019 Jan 8.


Concentrations of Thirteen Trace Metals in Scales of Three Nototheniid Fishes from Antarctica (James Ross Island, Antarctic Peninsula).

Roche K, Kuta J, Sedláček I, Červenka R, Tomanová K, Jurajda P.

Biol Trace Elem Res. 2019 Sep;191(1):214-223. doi: 10.1007/s12011-018-1598-1. Epub 2019 Jan 2.


Author Correction: The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms.

Incontro S, Díaz-Alonso J, Iafrati J, Vieira M, Asensio CS, Sohal VS, Roche KW, Bender KJ, Nicoll RA.

Nat Commun. 2018 Dec 3;9(1):5205. doi: 10.1038/s41467-018-07637-5.


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018;2:443-452. Epub 2018 Apr 23.


Isoform-specific cleavage of neuroligin-3 reduces synapse strength.

Bemben MA, Nguyen TA, Li Y, Wang T, Nicoll RA, Roche KW.

Mol Psychiatry. 2019 Jan;24(1):145-160. doi: 10.1038/s41380-018-0242-y. Epub 2018 Sep 21.


Selective 4-Thiouracil Labeling of RNA Transcripts within Latently Infected Cells after Infection with Human Cytomegalovirus Expressing Functional Uracil Phosphoribosyltransferase.

Roche KL, Nukui M, Krishna BA, O'Connor CM, Murphy EA.

J Virol. 2018 Oct 12;92(21). pii: e00880-18. doi: 10.1128/JVI.00880-18. Print 2018 Nov 1.


First data on uranium uptake in three nototheniid fishes from Antarctica (James Ross Island).

Roche K, Kuta J, Sedláček I, Červenka R, Tomanová K, Jurajda P.

Chemosphere. 2018 Nov;211:510-514. doi: 10.1016/j.chemosphere.2018.07.195. Epub 2018 Aug 1.


Sorting Five Human Tumor Types Reveals Specific Biomarkers and Background Classification Genes.

Roche KE, Weinstein M, Dunwoodie LJ, Poehlman WL, Feltus FA.

Sci Rep. 2018 May 25;8(1):8180. doi: 10.1038/s41598-018-26310-x.


The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms.

Incontro S, Díaz-Alonso J, Iafrati J, Vieira M, Asensio CS, Sohal VS, Roche KW, Bender KJ, Nicoll RA.

Nat Commun. 2018 May 25;9(1):2069. doi: 10.1038/s41467-018-04439-7. Erratum in: Nat Commun. 2018 Dec 3;9(1):5205.


A Dual Immunotherapy Nanoparticle Improves T-Cell Activation and Cancer Immunotherapy.

Mi Y, Smith CC, Yang F, Qi Y, Roche KC, Serody JS, Vincent BG, Wang AZ.

Adv Mater. 2018 Jun;30(25):e1706098. doi: 10.1002/adma.201706098. Epub 2018 Apr 25.


Nanoparticle co-delivery of wortmannin and cisplatin synergistically enhances chemoradiotherapy and reverses platinum resistance in ovarian cancer models.

Zhang M, Hagan CT 4th, Min Y, Foley H, Tian X, Yang F, Mi Y, Au KM, Medik Y, Roche K, Wagner K, Rodgers Z, Wang AZ.

Biomaterials. 2018 Jul;169:1-10. doi: 10.1016/j.biomaterials.2018.03.055. Epub 2018 Mar 31.


Metabotropic glutamate receptor trafficking.

Suh YH, Chang K, Roche KW.

Mol Cell Neurosci. 2018 Sep;91:10-24. doi: 10.1016/j.mcn.2018.03.014. Epub 2018 Mar 29. Review.


Placebo-controlled crossover assessment of mecasermin for the treatment of Rett syndrome.

O'Leary HM, Kaufmann WE, Barnes KV, Rakesh K, Kapur K, Tarquinio DC, Cantwell NG, Roche KJ, Rose SA, Walco AC, Bruck NM, Bazin GA, Holm IA, Alexander ME, Swanson LC, Baczewski LM, Poon C, Mayor Torres JM, Nelson CA 3rd, Sahin M.

Ann Clin Transl Neurol. 2018 Jan 31;5(3):323-332. doi: 10.1002/acn3.533. eCollection 2018 Mar. Erratum in: Ann Clin Transl Neurol. 2018 Jul 13;5(7):895. Poon C [added].


Impacts of Immigration Actions and News and the Psychological Distress of U.S. Latino Parents Raising Adolescents.

Roche KM, Vaquera E, White RMB, Rivera MI.

J Adolesc Health. 2018 May;62(5):525-531. doi: 10.1016/j.jadohealth.2018.01.004. Epub 2018 Mar 2.


A Process-Based Model for Bioturbation-Induced Mixing.

Aquino T, Roche KR, Aubeneau A, Packman AI, Bolster D.

Sci Rep. 2017 Oct 27;7(1):14287. doi: 10.1038/s41598-017-14705-1.


Acculturation Gap Distress among Latino Youth: Prospective Links to Family Processes and Youth Depressive Symptoms, Alcohol Use, and Academic Performance.

Nair RL, Roche KM, White RMB.

J Youth Adolesc. 2018 Jan;47(1):105-120. doi: 10.1007/s10964-017-0753-x. Epub 2017 Oct 14.


Outcomes Associated With a Five-Point Surgical Site Infection Prevention Bundle in Women Undergoing Surgery for Ovarian Cancer.

Lippitt MH, Fairbairn MG, Matsuno R, Stone RL, Tanner EJ 3rd, Wick EC, Angarita AC, Roche KL, Levinson KL, Bergstrom JE, Sinno AK, Curless MS, Wethington S, Temkin SM, Efron J, Hobson D, Fader AN.

Obstet Gynecol. 2017 Oct;130(4):756-764. doi: 10.1097/AOG.0000000000002213.


Co-delivery of paclitaxel and cisplatin with biocompatible PLGA-PEG nanoparticles enhances chemoradiotherapy in non-small cell lung cancer models.

Tian J, Min Y, Rodgers Z, Au KM, Hagan CT 4th, Zhang M, Roche K, Yang F, Wagner K, Wang AZ.

J Mater Chem B. 2017 Aug 14;5(30):6049-6057. doi: 10.1039/C7TB01370A. Epub 2017 Jul 5.


Discovering Condition-Specific Gene Co-Expression Patterns Using Gaussian Mixture Models: A Cancer Case Study.

Ficklin SP, Dunwoodie LJ, Poehlman WL, Watson C, Roche KE, Feltus FA.

Sci Rep. 2017 Aug 17;7(1):8617. doi: 10.1038/s41598-017-09094-4.


Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival?

Fader AN, Bergstrom J, Jernigan A, Tanner EJ 3rd, Roche KL, Stone RL, Levinson KL, Ricci S, Wethingon S, Wang TL, Shih IM, Yang B, Zhang G, Armstrong DK, Gaillard S, Michener C, DeBernardo R, Rose PG.

Gynecol Oncol. 2017 Oct;147(1):85-91. doi: 10.1016/j.ygyno.2017.07.127. Epub 2017 Jul 30.


Surgical site infection reduction bundle in patients with gynecologic cancer undergoing colon surgery.

Schiavone MB, Moukarzel L, Leong K, Zhou QC, Afonso AM, Iasonos A, Roche KL, Leitao MM Jr, Chi DS, Abu-Rustum NR, Zivanovic O.

Gynecol Oncol. 2017 Oct;147(1):115-119. doi: 10.1016/j.ygyno.2017.07.010. Epub 2017 Jul 19.


Phosphorylation of the kainate receptor (KAR) auxiliary subunit Neto2 at serine 409 regulates synaptic targeting of the KAR subunit GluK1.

Lomash RM, Sheng N, Li Y, Nicoll RA, Roche KW.

J Biol Chem. 2017 Sep 15;292(37):15369-15377. doi: 10.1074/jbc.M117.787903. Epub 2017 Jul 17.


Is there a Competition between Functional and Situational Affordances during Action Initiation with Everyday Tools?

Roche K, Chainay H.

Front Psychol. 2017 Jun 28;8:1073. doi: 10.3389/fpsyg.2017.01073. eCollection 2017.


Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy.

Min Y, Roche KC, Tian S, Eblan MJ, McKinnon KP, Caster JM, Chai S, Herring LE, Zhang L, Zhang T, DeSimone JM, Tepper JE, Vincent BG, Serody JS, Wang AZ.

Nat Nanotechnol. 2017 Sep;12(9):877-882. doi: 10.1038/nnano.2017.113. Epub 2017 Jun 26.


Cancer cell redirection biomarker discovery using a mutual information approach.

Roche K, Feltus FA, Park JP, Coissieux MM, Chang C, Chan VBS, Bentires-Alj M, Booth BW.

PLoS One. 2017 Jun 8;12(6):e0179265. doi: 10.1371/journal.pone.0179265. eCollection 2017.


Posttranslational modifications of neuroligins regulate neuronal and glial signaling.

Jeong J, Paskus JD, Roche KW.

Curr Opin Neurobiol. 2017 Aug;45:130-138. doi: 10.1016/j.conb.2017.05.017. Epub 2017 May 31. Review.


Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery.

Ejarque M, Borlaug M, Vilarrasa N, Martinez-Perez B, Llauradó G, Megía A, Helland T, Gutierrez C, Serena C, Folkestad O, Nuñez-Roa C, Roche K, Casajoana A, Fradera R, González-Clemente JM, López M, Mohn AC, Nedrebø BG, Nogueiras R, Mellgren G, Fernø J, Fernández-Veledo S, Vendrell J.

Transl Res. 2017 Jun;184:35-44.e4. doi: 10.1016/j.trsl.2017.03.001. Epub 2017 Mar 9.


Effect of particle size on the biodistribution, toxicity, and efficacy of drug-loaded polymeric nanoparticles in chemoradiotherapy.

Caster JM, Yu SK, Patel AN, Newman NJ, Lee ZJ, Warner SB, Wagner KT, Roche KC, Tian X, Min Y, Wang AZ.

Nanomedicine. 2017 Jul;13(5):1673-1683. doi: 10.1016/j.nano.2017.03.002. Epub 2017 Mar 11.


A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density.

Liu S, Zhou L, Yuan H, Vieira M, Sanz-Clemente A, Badger JD 2nd, Lu W, Traynelis SF, Roche KW.

J Neurosci. 2017 Apr 12;37(15):4093-4102. doi: 10.1523/JNEUROSCI.0827-16.2017. Epub 2017 Mar 10.


Optimal primary management of bulky stage IIIC ovarian, fallopian tube and peritoneal carcinoma: Are the only options complete gross resection at primary debulking surgery or neoadjuvant chemotherapy?

Sioulas VD, Schiavone MB, Kadouri D, Zivanovic O, Roche KL, O'Cearbhaill R, Abu-Rustum NR, Levine DA, Sonoda Y, Gardner GJ, Leitao MM Jr, Chi DS.

Gynecol Oncol. 2017 Apr;145(1):15-20. doi: 10.1016/j.ygyno.2017.02.023. Epub 2017 Feb 21.


MAGUKs: multifaceted synaptic organizers.

Won S, Levy JM, Nicoll RA, Roche KW.

Curr Opin Neurobiol. 2017 Apr;43:94-101. doi: 10.1016/j.conb.2017.01.006. Epub 2017 Feb 23. Review.


Perioperative fluid status and surgical outcomes in patients undergoing cytoreductive surgery for advanced epithelial ovarian cancer.

Desale MG, Tanner EJ 3rd, Sinno AK, Angarita AA, Fader AN, Stone RL, Levinson KL, Bristow RE, Roche KL.

Gynecol Oncol. 2016 Oct 28. pii: S0090-8258(16)31501-3. doi: 10.1016/j.ygyno.2016.10.027. [Epub ahead of print]


Optimizing MRI Logistics: Focused Process Improvements Can Increase Throughput in an Academic Radiology Department.

O'Brien JJ, Stormann J, Roche K, Cabral-Goncalves I, Monks A, Hallett D, Mortele KJ.

AJR Am J Roentgenol. 2017 Feb;208(2):W38-W44. doi: 10.2214/AJR.16.16680. Epub 2016 Dec 8.


Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer.

Tian J, Min Y, Rodgers Z, Wan X, Qiu H, Mi Y, Tian X, Wagner KT, Caster JM, Qi Y, Roche K, Zhang T, Cheng J, Wang AZ.

Nanomedicine. 2017 Apr;13(3):1301-1307. doi: 10.1016/j.nano.2016.11.007. Epub 2016 Nov 21.


CRLX101, a Nanoparticle-Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1α.

Tian X, Nguyen M, Foote HP, Caster JM, Roche KC, Peters CG, Wu P, Jayaraman L, Garmey EG, Tepper JE, Eliasof S, Wang AZ.

Cancer Res. 2017 Jan 1;77(1):112-122. doi: 10.1158/0008-5472.CAN-15-2951. Epub 2016 Oct 26. Erratum in: Cancer Res. 2017 Dec 1;77(23 ):6790-6791.


National Institutes of Health Pathways to Prevention Workshop: Advancing Research to Prevent Youth Suicide.

Little TD, Roche KM, Chow SM, Schenck AP, Byam LA.

Ann Intern Med. 2016 Dec 6;165(11):795-799. doi: 10.7326/M16-1568. Epub 2016 Oct 4.


An Integrated Experimental and Modeling Approach to Predict Sediment Mixing from Benthic Burrowing Behavior.

Roche KR, Aubeneau AF, Xie M, Aquino T, Bolster D, Packman AI.

Environ Sci Technol. 2016 Sep 20;50(18):10047-54. doi: 10.1021/acs.est.6b01704. Epub 2016 Sep 1.


Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue-derived endocrine factor with a potential role in fetal growth.

Martinez-Perez B, Ejarque M, Gutierrez C, Nuñez-Roa C, Roche K, Vila-Bedmar R, Ballesteros M, Redondo-Angulo I, Planavila A, Villarroya F, Vendrell J, Fernández-Veledo S, Megía A.

Transl Res. 2016 Dec;178:1-12. doi: 10.1016/j.trsl.2016.06.012. Epub 2016 Jul 9.


Single agent blinatumumab as frontline therapy for an 85-year-old patient with B cell precursor acute lymphoblastic leukemia.

Kim TK, Xu ML, Podoltsev NA, Prebet T, Barbarotta L, Amin K, Kasberg S, Roche K, Stahl M, Gore SD, Zeidan AM.

Ann Hematol. 2016 Oct;95(11):1895-8. doi: 10.1007/s00277-016-2761-4. Epub 2016 Jul 29. No abstract available.


PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.

Won S, Incontro S, Nicoll RA, Roche KW.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4736-44. doi: 10.1073/pnas.1609702113. Epub 2016 Jul 25.


Occurrence of the Afro-Asian species Mesocyclops ogunnus Onabamiro, 1957 (Crustacea: Copepoda) in the Amazon River basin.

Silva WM, Roche KF.

Braz J Biol. 2017 Mar;77(1):209-211. doi: 10.1590/1519-6984.14515. Epub 2016 Jul 4. No abstract available.

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