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Items: 12

1.

In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon.

Lima RB, Rocha e Silva LF, Melo MR, Costa JS, Picanço NS, Lima ES, Vasconcellos MC, Boleti AP, Santos JM, Amorim RC, Chaves FC, Coutinho JP, Tadei WP, Krettli AU, Pohlit AM.

Malar J. 2015 Dec 18;14:508. doi: 10.1186/s12936-015-0999-2.

2.

Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives.

Carneiro PF, Pinto MCRF, Marra RKF, da Silva FC, Resende JALC, Rocha E Silva LF, Alves HG, Barbosa GS, de Vasconcellos MC, Lima ES, Pohlit AM, Ferreira VF.

Eur J Med Chem. 2016 Jan 27;108:134-140. doi: 10.1016/j.ejmech.2015.11.020. Epub 2015 Nov 27.

PMID:
26638044
3.

In vivo evaluation of isolated triterpenes and semi-synthetic derivatives as antimalarial agents.

Rocha E Silva LF, Ramalhete C, Nogueira KL, Mulhovo S, Ferreira MJ, Pohlit AM.

Eur J Med Chem. 2015 Sep 18;102:398-402. doi: 10.1016/j.ejmech.2015.08.022. Epub 2015 Aug 13.

PMID:
26301556
4.

In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives.

Rocha e Silva LF, Nogueira KL, Pinto AC, Katzin AM, Sussmann RA, Muniz MP, de Andrade Neto VF, Chaves FC, Coutinho JP, Lima ES, Krettli AU, Tadei WP, Pohlit AM.

Antimicrob Agents Chemother. 2015;59(6):3271-80. doi: 10.1128/AAC.05012-14. Epub 2015 Mar 23.

5.

In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production.

Pereira TB, Rocha E Silva LF, Amorim RC, Melo MR, Zacardi de Souza RC, Eberlin MN, Lima ES, Vasconcellos MC, Pohlit AM.

Malar J. 2014 Aug 13;13:317. doi: 10.1186/1475-2875-13-317.

6.

Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog.

Montoia A, Rocha E Silva LF, Torres ZE, Costa DS, Henrique MC, Lima ES, Vasconcellos MC, Souza RC, Costa MR, Grafov A, Grafova I, Eberlin MN, Tadei WP, Amorim RC, Pohlit AM.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. Epub 2014 Apr 28.

PMID:
24813729
7.

Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids.

dos Santos Torres ZE, Silveira ER, Rocha e Silva LF, Lima ES, de Vasconcellos MC, de Andrade Uchoa DE, Filho RB, Pohlit AM.

Molecules. 2013 May 29;18(6):6281-97. doi: 10.3390/molecules18066281.

8.

Stability and antioxidant activity of semi-synthetic derivatives of 4-nerolidylcatechol.

Silva Lima E, Silva Pinto AC, Nogueira KL, Rocha e Silva LF, Oliveira de Almeida PD, Carvalho de Vasconcellos M, Chaves FC, Tadei WP, Pohlit AM.

Molecules. 2012 Dec 24;18(1):178-89. doi: 10.3390/molecules18010178.

9.

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.

Rocha e Silva LF, Montoia A, Amorim RC, Melo MR, Henrique MC, Nunomura SM, Costa MR, Andrade Neto VF, Costa DS, Dantas G, Lavrado J, Moreira R, Paulo A, Pinto AC, Tadei WP, Zacardi RS, Eberlin MN, Pohlit AM.

Phytomedicine. 2012 Dec 15;20(1):71-6. doi: 10.1016/j.phymed.2012.09.008. Epub 2012 Oct 23.

10.

Antimalarial activity of ellipticine.

Pohlit AM, Rocha e Silva LF, Henrique MC, Montoia A, Amorim RC, Nunomura SM, Andrade-Neto VF.

Phytomedicine. 2012 Aug 15;19(11):1049. doi: 10.1016/j.phymed.2012.06.005. Epub 2012 Jul 26. No abstract available.

PMID:
22841488
11.

In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.

Mota ML, Lobo LT, Costa JM, Costa LS, Rocha HA, Rocha e Silva LF, Pohlit AM, Neto VF.

Planta Med. 2012 May;78(7):658-64. doi: 10.1055/s-0031-1298333. Epub 2012 Mar 22.

PMID:
22441836
12.

In vivo and in vitro antimalarial activity of 4-nerolidylcatechol.

Rocha E Silva LF, Silva Pinto AC, Pohlit AM, Quignard EL, Vieira PP, Tadei WP, Chaves FC, Samonek JF, Lima CA, Costa MR, Alecrim Md, Andrade-Neto VF.

Phytother Res. 2011 Aug;25(8):1181-8. doi: 10.1002/ptr.3424. Epub 2011 Feb 8.

PMID:
21302338

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