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Items: 1 to 50 of 152

1.

Correction: Resveratrol Exerts Antiproliferative Activity and Induces Apoptosis in Waldenström Macroglobulinemia.

Roccaro AM, Leleu X, Sacco A, Moreau AS, Hatjiharissi E, Jia X, Xu L, Ciccarelli B, Patterson CJ, Ngo HT, Russo D, Vacca A, Dammacco F, Anderson KC, Ghobrial IM, Treon SP.

Clin Cancer Res. 2019 Aug 1;25(15):4860. doi: 10.1158/1078-0432.CCR-19-2051. No abstract available.

PMID:
31371310
2.

Circulating microRNAs and Their Role in Multiple Myeloma.

Federico C, Sacco A, Belotti A, Ribolla R, Cancelli V, Giacomini A, Ronca R, Chiarini M, Imberti L, Marini M, Rossi G, Presta M, Paiva B, Roccaro AM.

Noncoding RNA. 2019 May 2;5(2). pii: E37. doi: 10.3390/ncrna5020037. Review.

3.

Targeting transcription factors in multiple myeloma: evolving therapeutic strategies.

Li S, Vallet S, Sacco A, Roccaro A, Lentzsch S, Podar K.

Expert Opin Investig Drugs. 2019 May;28(5):445-462. doi: 10.1080/13543784.2019.1605354. Epub 2019 Apr 16. Review.

PMID:
30963799
4.

Citron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma.

Sahin I, Kawano Y, Sklavenitis-Pistofidis R, Moschetta M, Mishima Y, Manier S, Sacco A, Carrasco R, Fonseca R, Roccaro AM, Witzig T, Ghobrial IM.

Blood Adv. 2019 Apr 9;3(7):995-1002. doi: 10.1182/bloodadvances.2018028456.

5.

Profiling of circulating exosomal miRNAs in patients with Waldenström Macroglobulinemia.

Bouyssou JM, Liu CJ, Bustoros M, Sklavenitis-Pistofidis R, Aljawai Y, Manier S, Yosef A, Sacco A, Kokubun K, Tsukamoto S, Perilla Glen A, Huynh D, Castillo JJ, Treon SP, Leblond V, Hermine O, Roccaro AM, Ghobrial IM, Capelletti M.

PLoS One. 2018 Oct 4;13(10):e0204589. doi: 10.1371/journal.pone.0204589. eCollection 2018.

6.

Inhibition of microRNA-138 enhances bone formation in multiple myeloma bone marrow niche.

Tsukamoto S, Løvendorf MB, Park J, Salem KZ, Reagan MR, Manier S, Zavidij O, Rahmat M, Huynh D, Takagi S, Kawano Y, Kokubun K, Thrue CA, Nagano K, Petri A, Roccaro AM, Capelletti M, Baron R, Kauppinen S, Ghobrial IM.

Leukemia. 2018 Aug;32(8):1739-1750. doi: 10.1038/s41375-018-0161-6. Epub 2018 Jun 20.

PMID:
29925904
7.

Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.

Kurdi AT, Glavey SV, Bezman NA, Jhatakia A, Guerriero JL, Manier S, Moschetta M, Mishima Y, Roccaro A, Detappe A, Liu CJ, Sacco A, Huynh D, Tai YT, Robbins MD, Azzi J, Ghobrial IM.

Mol Cancer Ther. 2018 Jul;17(7):1454-1463. doi: 10.1158/1535-7163.MCT-17-0998. Epub 2018 Apr 13.

8.

Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression.

Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine TH, Manier S, Mishima Y, Murakami N, Bustoros M, Pistofidis RS, Reidy M, Shen YJ, Rahmat M, Lukyanchykov P, Karreci ES, Tsukamoto S, Shi J, Takagi S, Huynh D, Sacco A, Tai YT, Chesi M, Bergsagel PL, Roccaro AM, Azzi J, Ghobrial IM.

J Clin Invest. 2018 Jun 1;128(6):2487-2499. doi: 10.1172/JCI88169. Epub 2018 May 14.

9.

Cryptococcal-related meningoencephalitis in a patient with sarcoidosis and CD4 lymphocytopenia: thorough immunological characterization of lymphocyte homeostasis.

Giustini V, Sottini A, Belleri S, Bertoli D, Roccaro AM, Montanelli A, Filippini M, Fontanella M, Imberti L.

J Neurosurg Sci. 2018 Feb 23. doi: 10.23736/S0390-5616.18.04375-8. [Epub ahead of print]

PMID:
29480693
10.

Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation.

Takagi S, Tsukamoto S, Park J, Johnson KE, Kawano Y, Moschetta M, Liu CJ, Mishima Y, Kokubun K, Manier S, Salem KZ, Huynh D, Sacco A, Forward J, Roccaro AM, Battinelli EM, Ghobrial IM.

Clin Cancer Res. 2018 May 15;24(10):2430-2439. doi: 10.1158/1078-0432.CCR-17-2003. Epub 2018 Feb 9.

11.

Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice.

Bornstein S, Moschetta M, Kawano Y, Sacco A, Huynh D, Brooks D, Manier S, Fairfield H, Falank C, Roccaro AM, Nagano K, Baron R, Bouxein M, Vary C, Ghobrial IM, Rosen CJ, Reagan MR.

Endocrinology. 2017 Oct 1;158(10):3369-3385. doi: 10.1210/en.2017-00299.

12.

Bone Marrow Stroma and Vascular Contributions to Myeloma Bone Homing.

Moschetta M, Kawano Y, Sacco A, Belotti A, Ribolla R, Chiarini M, Giustini V, Bertoli D, Sottini A, Valotti M, Ghidini C, Serana F, Malagola M, Imberti L, Russo D, Montanelli A, Rossi G, Reagan MR, Maiso P, Paiva B, Ghobrial IM, Roccaro AM.

Curr Osteoporos Rep. 2017 Oct;15(5):499-506. doi: 10.1007/s11914-017-0399-3. Review.

PMID:
28889371
13.

Bacterial Blood Stream Infections Negatively Impact on Outcome of Patients Treated with Allogeneic Stem Cell Transplantation: 6 Years Single-Centre Experience.

Malagola M, Rambaldi B, Ravizzola G, Cattaneo C, Borlenghi E, Polverelli N, Turra A, Morello E, Skert C, Cancelli V, Cattina F, Giannetta G, Bernardi S, Perucca S, Almici C, Roccaro A, Signorini L, Stellini R, Castelli F, Caruso A, Russo D.

Mediterr J Hematol Infect Dis. 2017 Jun 20;9(1):e2017036. doi: 10.4084/MJHID.2017.036. eCollection 2017.

14.

A novel in vivo model for studying conditional dual loss of BLIMP-1 and p53 in B-cells, leading to tumor transformation.

Sacco A, Kawano Y, Moschetta M, Zavidij O, Huynh D, Reagan M, Mishima Y, Manier S, Park J, Morgan E, Takagi S, Wong KK, Carrasco R, Ghobrial IM, Roccaro AM.

Am J Hematol. 2017 Aug;92(8):E138-E145. doi: 10.1002/ajh.24778. Epub 2017 Jun 15.

15.

The importance of the genomic landscape in Waldenström's Macroglobulinemia for targeted therapeutical interventions.

Sacco A, Fenotti A, Affò L, Bazzana S, Russo D, Presta M, Malagola M, Anastasia A, Motta M, Patterson CJ, Rossi G, Imberti L, Treon SP, Ghobrial IM, Roccaro AM.

Oncotarget. 2017 May 23;8(21):35435-35444. doi: 10.18632/oncotarget.16130. Review.

16.

Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs.

Tessitore MV, Sottini A, Roccaro AM, Ghidini C, Bernardi S, Martellosio G, Serana F, Imberti L.

J Transl Med. 2017 Apr 5;15(1):70. doi: 10.1186/s12967-017-1169-9.

17.

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

Mishima Y, Paiva B, Shi J, Park J, Manier S, Takagi S, Massoud M, Perilla-Glen A, Aljawai Y, Huynh D, Roccaro AM, Sacco A, Capelletti M, Detappe A, Alignani D, Anderson KC, Munshi NC, Prosper F, Lohr JG, Ha G, Freeman SS, Van Allen EM, Adalsteinsson VA, Michor F, San Miguel JF, Ghobrial IM.

Cell Rep. 2017 Apr 4;19(1):218-224. doi: 10.1016/j.celrep.2017.03.025.

18.

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

Glavey SV, Naba A, Manier S, Clauser K, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, O'Dwyer ME, Asara JM, Palumbo A, Roccaro AM, Hynes RO, Ghobrial IM.

Leukemia. 2017 Nov;31(11):2426-2434. doi: 10.1038/leu.2017.102. Epub 2017 Mar 27.

PMID:
28344315
19.

Prognostic role of circulating exosomal miRNAs in multiple myeloma.

Manier S, Liu CJ, Avet-Loiseau H, Park J, Shi J, Campigotto F, Salem KZ, Huynh D, Glavey SV, Rivotto B, Sacco A, Roccaro AM, Bouyssou J, Minvielle S, Moreau P, Facon T, Leleu X, Weller E, Trippa L, Ghobrial IM.

Blood. 2017 Apr 27;129(17):2429-2436. doi: 10.1182/blood-2016-09-742296. Epub 2017 Feb 17.

20.

Multiple Myeloma and the Immune Microenvironment.

Kawano Y, Roccaro AM, Ghobrial IM, Azzi J.

Curr Cancer Drug Targets. 2017;17(9):806-818. doi: 10.2174/1568009617666170214102301. Review.

PMID:
28201978
21.

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.

Fulciniti M, Martinez-Lopez J, Senapedis W, Oliva S, Lakshmi Bandi R, Amodio N, Xu Y, Szalat R, Gulla A, Samur MK, Roccaro A, Linares M, Cea M, Baloglu E, Argueta C, Landesman Y, Shacham S, Liu S, Schenone M, Wu SL, Karger B, Prabhala R, Anderson KC, Munshi NC.

Blood. 2017 Apr 20;129(16):2233-2245. doi: 10.1182/blood-2016-06-724831. Epub 2017 Jan 17.

22.

B- and T-lymphocyte number and function in HIV+/HIV- lymphoma patients treated with high-dose chemotherapy and autologous bone marrow transplantation.

Bertoli D, Re A, Chiarini M, Sottini A, Serana F, Giustini V, Roccaro AM, Cattaneo C, Caimi L, Rossi G, Imberti L.

Sci Rep. 2016 Dec 1;6:37995. doi: 10.1038/srep37995.

23.

Exosomes in Tumor Angiogenesis.

Salem KZ, Moschetta M, Sacco A, Imberti L, Rossi G, Ghobrial IM, Manier S, Roccaro AM.

Methods Mol Biol. 2016;1464:25-34.

PMID:
27858353
24.

Epigenomics in Waldenstrom's macroglobulinaemia.

Sacco A, Fenotti A, Bazzana S, Imberti L, Rossi G, Patterson CJ, Treon SP, Ghobrial IM, Roccaro AM.

Best Pract Res Clin Haematol. 2016 Jun;29(2):156-160. doi: 10.1016/j.beha.2016.08.022. Epub 2016 Sep 25. Review.

PMID:
27825461
25.

The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma.

Manier S, Powers JT, Sacco A, Glavey SV, Huynh D, Reagan MR, Salem KZ, Moschetta M, Shi J, Mishima Y, Roche-Lestienne C, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM.

Leukemia. 2017 Apr;31(4):853-860. doi: 10.1038/leu.2016.296. Epub 2016 Oct 24.

26.

Epigenetics in Multiple Myeloma.

Glavey SV, Manier S, Sacco A, Salem K, Kawano Y, Bouyssou J, Ghobrial IM, Roccaro AM.

Cancer Treat Res. 2016;169:35-49. Review.

PMID:
27696257
27.

Genomic Aberrations in Multiple Myeloma.

Manier S, Salem K, Glavey SV, Roccaro AM, Ghobrial IM.

Cancer Treat Res. 2016;169:23-34. Review.

PMID:
27696256
28.

Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma.

Manier S, Kawano Y, Bianchi G, Roccaro AM, Ghobrial IM.

Curr Opin Hematol. 2016 Jul;23(4):426-33. doi: 10.1097/MOH.0000000000000259. Review.

PMID:
27101529
29.

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.

Roccaro AM, Sacco A, Shi J, Chiarini M, Perilla-Glen A, Manier S, Glavey S, Aljawai Y, Mishima Y, Kawano Y, Moschetta M, Correll M, Improgo MR, Brown JR, Imberti L, Rossi G, Castillo JJ, Treon SP, Freedman ML, Van Allen EM, Hide W, Hiller E, Rainville I, Ghobrial IM.

Blood. 2016 May 26;127(21):2598-606. doi: 10.1182/blood-2015-11-680199. Epub 2016 Feb 22.

PMID:
26903547
30.

Targeting vasculogenesis to prevent progression in multiple myeloma.

Moschetta M, Mishima Y, Kawano Y, Manier S, Paiva B, Palomera L, Aljawai Y, Calcinotto A, Unitt C, Sahin I, Sacco A, Glavey S, Shi J, Reagan MR, Prosper F, Bellone M, Chesi M, Bergsagel LP, Vacca A, Roccaro AM, Ghobrial IM.

Leukemia. 2016 May;30(5):1103-15. doi: 10.1038/leu.2016.3. Epub 2016 Feb 3.

PMID:
26859080
31.

Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model.

Sacco A, Roccaro AM, Ma D, Shi J, Mishima Y, Moschetta M, Chiarini M, Munshi N, Handin RI, Ghobrial IM.

Cancer Res. 2016 Jan 15;76(2):463-71. doi: 10.1158/0008-5472.CAN-15-1926. Epub 2016 Jan 7.

32.

Targeting SDF-1 in multiple myeloma tumor microenvironment.

Bouyssou JM, Ghobrial IM, Roccaro AM.

Cancer Lett. 2016 Sep 28;380(1):315-8. doi: 10.1016/j.canlet.2015.11.028. Epub 2015 Nov 30. Review.

PMID:
26655999
33.

Aberrant Levels of miRNAs in Bone Marrow Microenvironment and Peripheral Blood of Myeloma Patients and Disease Progression.

Wang W, Corrigan-Cummins M, Barber EA, Saleh LM, Zingone A, Ghafoor A, Costello R, Zhang Y, Kurlander RJ, Korde N, Roccaro AM, Ghobrial IM, Landgren O, Calvo KR.

J Mol Diagn. 2015 Nov;17(6):669-78. doi: 10.1016/j.jmoldx.2015.06.006. Epub 2015 Sep 30.

34.

CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.

Roccaro AM, Mishima Y, Sacco A, Moschetta M, Tai YT, Shi J, Zhang Y, Reagan MR, Huynh D, Kawano Y, Sahin I, Chiarini M, Manier S, Cea M, Aljawai Y, Glavey S, Morgan E, Pan C, Michor F, Cardarelli P, Kuhne M, Ghobrial IM.

Cell Rep. 2015 Jul 28;12(4):622-35. doi: 10.1016/j.celrep.2015.06.059. Epub 2015 Jul 16.

35.

Phase I/II trial of everolimus in combination with bortezomib and rituximab (RVR) in relapsed/refractory Waldenstrom macroglobulinemia.

Ghobrial IM, Redd R, Armand P, Banwait R, Boswell E, Chuma S, Huynh D, Sacco A, Roccaro AM, Perilla-Glen A, Noonan K, MacNabb M, Leblebjian H, Warren D, Henrick P, Castillo JJ, Richardson PG, Matous J, Weller E, Treon SP.

Leukemia. 2015 Dec;29(12):2338-46. doi: 10.1038/leu.2015.164. Epub 2015 Jul 3.

PMID:
26139427
36.

Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation.

Weinstock M, Aljawai Y, Morgan EA, Laubach J, Gannon M, Roccaro AM, Varga C, Mitsiades CS, Paba-Prada C, Schlossman R, Munshi N, Anderson KC, Richardson PP, Weller E, Ghobrial IM.

Br J Haematol. 2015 Jun;169(6):851-8. doi: 10.1111/bjh.13383. Epub 2015 Apr 1.

37.

Metabolic signature identifies novel targets for drug resistance in multiple myeloma.

Maiso P, Huynh D, Moschetta M, Sacco A, Aljawai Y, Mishima Y, Asara JM, Roccaro AM, Kimmelman AC, Ghobrial IM.

Cancer Res. 2015 May 15;75(10):2071-82. doi: 10.1158/0008-5472.CAN-14-3400. Epub 2015 Mar 13.

38.

The cancer glycome: carbohydrates as mediators of metastasis.

Glavey SV, Huynh D, Reagan MR, Manier S, Moschetta M, Kawano Y, Roccaro AM, Ghobrial IM, Joshi L, O'Dwyer ME.

Blood Rev. 2015 Jul;29(4):269-79. doi: 10.1016/j.blre.2015.01.003. Epub 2015 Jan 23. Review.

PMID:
25636501
39.

Targeting the bone marrow microenvironment in multiple myeloma.

Kawano Y, Moschetta M, Manier S, Glavey S, Görgün GT, Roccaro AM, Anderson KC, Ghobrial IM.

Immunol Rev. 2015 Jan;263(1):160-72. doi: 10.1111/imr.12233. Review.

PMID:
25510276
40.

Extramedullary Waldenström macroglobulinemia.

Banwait R, Aljawai Y, Cappuccio J, McDiarmid S, Morgan EA, Leblebjian H, Roccaro AM, Laubach J, Castillo JJ, Paba-Prada C, Treon S, Redd R, Weller E, Ghobrial IM.

Am J Hematol. 2015 Feb;90(2):100-4. doi: 10.1002/ajh.23880. Epub 2014 Nov 19.

41.

Global epigenetic regulation of microRNAs in multiple myeloma.

Zhang W, Wang YE, Zhang Y, Leleu X, Reagan M, Zhang Y, Mishima Y, Glavey S, Manier S, Sacco A, Jiang B, Roccaro AM, Ghobrial IM.

PLoS One. 2014 Oct 17;9(10):e110973. doi: 10.1371/journal.pone.0110973. eCollection 2014.

42.

SDF-1 inhibition targets the bone marrow niche for cancer therapy.

Roccaro AM, Sacco A, Purschke WG, Moschetta M, Buchner K, Maasch C, Zboralski D, Zöllner S, Vonhoff S, Mishima Y, Maiso P, Reagan MR, Lonardi S, Ungari M, Facchetti F, Eulberg D, Kruschinski A, Vater A, Rossi G, Klussmann S, Ghobrial IM.

Cell Rep. 2014 Oct 9;9(1):118-128. doi: 10.1016/j.celrep.2014.08.042. Epub 2014 Sep 25.

43.

Pyk2 promotes tumor progression in multiple myeloma.

Zhang Y, Moschetta M, Huynh D, Tai YT, Zhang Y, Zhang W, Mishima Y, Ring JE, Tam WF, Xu Q, Maiso P, Reagan M, Sahin I, Sacco A, Manier S, Aljawai Y, Glavey S, Munshi NC, Anderson KC, Pachter J, Roccaro AM, Ghobrial IM.

Blood. 2014 Oct 23;124(17):2675-86. doi: 10.1182/blood-2014-03-563981. Epub 2014 Sep 12.

44.

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

Reagan MR, Mishima Y, Glavey SV, Zhang Y, Manier S, Lu ZN, Memarzadeh M, Zhang Y, Sacco A, Aljawai Y, Shi J, Tai YT, Ready JE, Kaplan DL, Roccaro AM, Ghobrial IM.

Blood. 2014 Nov 20;124(22):3250-9. doi: 10.1182/blood-2014-02-558007. Epub 2014 Sep 9.

45.

CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma.

Azab AK, Sahin I, Moschetta M, Mishima Y, Burwick N, Zimmermann J, Romagnoli B, Patel K, Chevalier E, Roccaro AM, Ghobria IM.

Blood. 2014 Sep 18;124(12):1905-14.

46.

The role of miRNAs in plasma cell dyscrasias.

Glavey S, Manier S, Sacco A, Rossi G, Ghobrial IM, Roccaro AM.

Microrna. 2014;2(3):165-73. Review.

PMID:
25069440
47.

microRNA aberrations and their role in supporting hematologic malignancies.

Roccaro AM, Ghobrial IM.

Microrna. 2014;2(3):157. No abstract available.

PMID:
25069438
48.

The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma.

Glavey SV, Manier S, Natoni A, Sacco A, Moschetta M, Reagan MR, Murillo LS, Sahin I, Wu P, Mishima Y, Zhang Y, Zhang W, Zhang Y, Morgan G, Joshi L, Roccaro AM, Ghobrial IM, O'Dwyer ME.

Blood. 2014 Sep 11;124(11):1765-76. doi: 10.1182/blood-2014-03-560862. Epub 2014 Jul 24.

49.

Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib.

Sahin I, Azab F, Mishima Y, Moschetta M, Tsang B, Glavey SV, Manier S, Zhang Y, Sacco A, Roccaro AM, Azab AK, Ghobrial IM.

Am J Hematol. 2014 Nov;89(11):1030-6. doi: 10.1002/ajh.23814. Epub 2014 Aug 12.

50.

Altered cytokine and chemokine profiles in multiple myeloma and its precursor disease.

Zingone A, Wang W, Corrigan-Cummins M, Wu SP, Plyler R, Korde N, Kwok M, Manasanch EE, Tageja N, Bhutani M, Mulquin M, Zuchlinski D, Yancey MA, Roschewski M, Zhang Y, Roccaro AM, Ghobrial IM, Calvo KR, Landgren O.

Cytokine. 2014 Oct;69(2):294-7. doi: 10.1016/j.cyto.2014.05.017. Epub 2014 Jul 17.

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