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Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy.

Rocca WA, Grossardt BR, Geda YE, Gostout BS, Bower JH, Maraganore DM, de Andrade M, Melton LJ 3rd.

Menopause. 2018 Nov;25(11):1275-1285. doi: 10.1097/GME.0000000000001229.


Association of Bilateral Salpingo-Oophorectomy Before Menopause Onset With Medial Temporal Lobe Neurodegeneration.

Zeydan B, Tosakulwong N, Schwarz CG, Senjem ML, Gunter JL, Reid RI, Gazzuola Rocca L, Lesnick TG, Smith CY, Bailey KR, Lowe VJ, Roberts RO, Jack CR Jr, Petersen RC, Miller VM, Mielke MM, Rocca WA, Kantarci K.

JAMA Neurol. 2018 Oct 15. doi: 10.1001/jamaneurol.2018.3057. [Epub ahead of print]


Personal, reproductive, and familial characteristics associated with bilateral oophorectomy in premenopausal women: A population-based case-control study.

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Stewart EA, Mielke MM, Kantarci K, Miller VM.

Maturitas. 2018 Nov;117:64-77. doi: 10.1016/j.maturitas.2018.09.002. Epub 2018 Sep 14.


Loss of Ovarian Hormones and Accelerated Somatic and Mental Aging.

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Kirkland JL, LeBrasseur NK, Schafer MJ, Mielke MM, Kantarci K, Stewart EA, Miller VM.

Physiology (Bethesda). 2018 Nov 1;33(6):374-383. doi: 10.1152/physiol.00024.2018.


In Reply.

Laughlin-Tommaso SK, Smith CY, Weaver AL, Khan Z, Stewart EA, Rocca WA.

Menopause. 2018 Oct 8. doi: 10.1097/GME.0000000000001242. [Epub ahead of print] No abstract available.


The burden of Parkinson's disease: a worldwide perspective.

Rocca WA.

Lancet Neurol. 2018 Nov;17(11):928-929. doi: 10.1016/S1474-4422(18)30355-7. Epub 2018 Oct 1. No abstract available.


CKD in Patients with Bilateral Oophorectomy.

Kattah AG, Smith CY, Gazzuola Rocca L, Grossardt BR, Garovic VD, Rocca WA.

Clin J Am Soc Nephrol. 2018 Nov 7;13(11):1649-1658. doi: 10.2215/CJN.03990318. Epub 2018 Sep 19.


Brain structure and cognition 3 years after the end of an early menopausal hormone therapy trial.

Kantarci K, Tosakulwong N, Lesnick TG, Zuk SM, Lowe VJ, Fields JA, Gunter JL, Senjem ML, Settell ML, Gleason CE, Shuster LT, Bailey KR, Dowling NM, Asthana S, Jack CR Jr, Rocca WA, Miller VM.

Neurology. 2018 Apr 17;90(16):e1404-e1412. doi: 10.1212/WNL.0000000000005325. Epub 2018 Mar 21.


Rochester Epidemiology Project Data Exploration Portal.

St Sauver JL, Grossardt BR, Finney Rutten LJ, Roger VL, Majerus M, Jensen DW, Brue SM, Bock-Goodner CM, Rocca WA.

Prev Chronic Dis. 2018 Apr 12;15:E42. doi: 10.5888/pcd15.170242.


What's in a name: are menopausal "hot flashes" a symptom of menopause or a manifestation of neurovascular dysregulation?

Miller VM, Kling JM, Files JA, Joyner MJ, Kapoor E, Moyer AM, Rocca WA, Faubion SS.

Menopause. 2018 Jun;25(6):700-703. doi: 10.1097/GME.0000000000001065.


Parkinson disease with and without Dementia: A prevalence study and future projections.

Savica R, Grossardt BR, Rocca WA, Bower JH.

Mov Disord. 2018 Apr;33(4):537-543. doi: 10.1002/mds.27277. Epub 2018 Jan 22.


Data Resource Profile: Expansion of the Rochester Epidemiology Project medical records-linkage system (E-REP).

Rocca WA, Grossardt BR, Brue SM, Bock-Goodner CM, Chamberlain AM, Wilson PM, Finney Rutten LJ, St Sauver JL.

Int J Epidemiol. 2018 Apr 1;47(2):368-368j. doi: 10.1093/ije/dyx268. No abstract available.


Is multiple system atrophy an infectious disease?

Wenning G, Trojanowski JQ, Kaufmann H, Wisniewski T, Rocca WA, Low PA.

Ann Neurol. 2018 Jan;83(1):10-12. doi: 10.1002/ana.25132. Epub 2018 Jan 14. No abstract available.


Cardiovascular and metabolic morbidity after hysterectomy with ovarian conservation: a cohort study.

Laughlin-Tommaso SK, Khan Z, Weaver AL, Smith CY, Rocca WA, Stewart EA.

Menopause. 2018 May;25(5):483-492. doi: 10.1097/GME.0000000000001043.


Prevalence of and indications for antipsychotic use in Parkinson's disease.

Bower JH, Grossardt BR, Rocca WA, Savica R.

Mov Disord. 2018 Feb;33(2):325-328. doi: 10.1002/mds.27256. Epub 2017 Dec 26.


Data Registry on Experiences of Aging, Menopause, and Sexuality (DREAMS): A cohort profile.

Faubion SS, Kapoor E, Kling JM, Kuhle CL, Sood R, Rullo JE, Thielen JM, Shuster LT, Rocca WA, Hilsaca KSF, Mara KC, Schroeder DR, Miller VM.

Maturitas. 2018 Jan;107:44-49. doi: 10.1016/j.maturitas.2017.09.013. Epub 2017 Oct 5. Review.


Cohort profile: the Mayo Clinic Cohort Study of Oophorectomy and Aging-2 (MOA-2) in Olmsted County, Minnesota (USA).

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Stewart EA, Mielke MM, Kantarci K, Miller VM.

BMJ Open. 2017 Nov 20;7(11):e018861. doi: 10.1136/bmjopen-2017-018861.


Adverse childhood experiences and adult abuse are predictors of hysterectomy and oophorectomy.

Gazzuola Rocca L, Smith CY, Stewart EA, Rocca WA.

Maturitas. 2017 Dec;106:95-96. doi: 10.1016/j.maturitas.2017.08.001. Epub 2017 Aug 3. No abstract available.


The future burden of Parkinson's disease.

Rocca WA.

Mov Disord. 2018 Jan;33(1):8-9. doi: 10.1002/mds.27114. Epub 2017 Aug 7. No abstract available.


Response to Letter by Friedman on "Incidence and time trends of drug-induced parkinsonism: A 30-year population-based study".

Rocca WA, Savica R, Grossardt BR.

Mov Disord. 2017 Jul;32(7):1111-1112. doi: 10.1002/mds.27051. Epub 2017 Jun 14. No abstract available.


Adverse childhood or adult experiences and risk of bilateral oophorectomy: a population-based case-control study.

Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Stewart EA, Rocca WA.

BMJ Open. 2017 Jun 7;7(5):e016045. doi: 10.1136/bmjopen-2017-016045.


Effect of the American Heart Association 2007 Guidelines on the Practice of Dental Prophylaxis for the Prevention of Infective Endocarditis in Olmsted County, Minnesota.

DeSimone DC, El Rafei A, Challener DW, Carr AB, Kelly JA, Rocca WA, St Sauver JL, Bock-Goodner CM, Lahr BD, Steckelberg JM, Wilson WR, Baddour LM.

Mayo Clin Proc. 2017 May 10. pii: S0025-6196(17)30238-0. doi: 10.1016/j.mayocp.2017.03.013. [Epub ahead of print]


Survival and Causes of Death Among People With Clinically Diagnosed Synucleinopathies With Parkinsonism: A Population-Based Study.

Savica R, Grossardt BR, Bower JH, Ahlskog JE, Boeve BF, Graff-Radford J, Rocca WA, Mielke MM.

JAMA Neurol. 2017 Jul 1;74(7):839-846. doi: 10.1001/jamaneurol.2017.0603.


Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC.

Lancet Neurol. 2017 Jun;16(6):435-444. doi: 10.1016/S1474-4422(17)30077-7. Epub 2017 Apr 26.


Clinical Trials Targeting Aging and Age-Related Multimorbidity.

Espeland MA, Crimmins EM, Grossardt BR, Crandall JP, Gelfond JA, Harris TB, Kritchevsky SB, Manson JE, Robinson JG, Rocca WA, Temprosa M, Thomas F, Wallace R, Barzilai N; Multimorbidity Clinical Trials Consortium.

J Gerontol A Biol Sci Med Sci. 2017 Mar 1;72(3):355-361. doi: 10.1093/gerona/glw220.


Linking medical and dental health record data: a partnership with the Rochester Epidemiology Project.

St Sauver JL, Carr AB, Yawn BP, Grossardt BR, Bock-Goodner CM, Klein LL, Pankratz JJ, Finney Rutten LJ, Rocca WA.

BMJ Open. 2017 Mar 29;7(3):e012528. doi: 10.1136/bmjopen-2016-012528.


Bilateral Oophorectomy and Accelerated Aging: Cause or Effect?

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Kirkland JL, Stewart EA, Miller VM.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1213-1217. doi: 10.1093/gerona/glx026.


Alzheimer's disease: The next frontier-Special Report 2017.

Karlawish J, Jack CR Jr, Rocca WA, Snyder HM, Carrillo MC.

Alzheimers Dement. 2017 Apr;13(4):374-380. doi: 10.1016/j.jalz.2017.02.006. Epub 2017 Mar 14.


Time, Sex, Gender, History, and Dementia.

Rocca WA.

Alzheimer Dis Assoc Disord. 2017 Jan-Mar;31(1):76-79. doi: 10.1097/WAD.0000000000000187.


Salpingo-oophorectomy at the Time of Benign Hysterectomy: A Systematic Review.

Rocca WA, Faubion SS, Stewart EA, Miller VM.

Obstet Gynecol. 2017 Jan;129(1):202-203. doi: 10.1097/AOG.0000000000001828. No abstract available.


Incidence and time trends of drug-induced parkinsonism: A 30-year population-based study.

Savica R, Grossardt BR, Bower JH, Ahlskog JE, Mielke MM, Rocca WA.

Mov Disord. 2017 Feb;32(2):227-234. doi: 10.1002/mds.26839. Epub 2016 Oct 25.


Trends in the Incidence of Parkinson Disease-Reply.

Rocca WA, Savica R, Grossardt BR.

JAMA Neurol. 2016 Dec 1;73(12):1498-1499. doi: 10.1001/jamaneurol.2016.3847. No abstract available.


Preeclampsia and ESRD: The Role of Shared Risk Factors.

Kattah AG, Scantlebury DC, Agarwal S, Mielke MM, Rocca WA, Weaver AL, Vaughan LE, Miller VM, Weissgerber TL, White W, Garovic VD.

Am J Kidney Dis. 2017 Apr;69(4):498-505. doi: 10.1053/j.ajkd.2016.07.034. Epub 2016 Oct 1.


Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort Study.

Rocca WA, Gazzuola-Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Kirkland JL, Stewart EA, Miller VM.

Mayo Clin Proc. 2016 Nov;91(11):1577-1589. doi: 10.1016/j.mayocp.2016.08.002. Epub 2016 Sep 29.


Long-Term Abdominopelvic Surgical Morbidity After Abdominal Vs. Minimally Invasive Hysterectomy With Ovarian Conservation: A Population-Based Cohort Study.

Khan Z, Laughlin-Tommaso SK, Weaver AL, Schleck CD, Rocca WA, Stewart EA.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S65. doi: 10.1016/j.jmig.2015.08.173. Epub 2015 Oct 15. No abstract available.


Effects of hormone therapy on brain structure: A randomized controlled trial.

Kantarci K, Tosakulwong N, Lesnick TG, Zuk SM, Gunter JL, Gleason CE, Wharton W, Dowling NM, Vemuri P, Senjem ML, Shuster LT, Bailey KR, Rocca WA, Jack CR Jr, Asthana S, Miller VM.

Neurology. 2016 Aug 30;87(9):887-96. doi: 10.1212/WNL.0000000000002970. Epub 2016 Jul 29.


Time Trends in the Incidence of Parkinson Disease.

Savica R, Grossardt BR, Bower JH, Ahlskog JE, Rocca WA.

JAMA Neurol. 2016 Aug 1;73(8):981-9. doi: 10.1001/jamaneurol.2016.0947.


Early Postmenopausal Transdermal 17β-Estradiol Therapy and Amyloid-β Deposition.

Kantarci K, Lowe VJ, Lesnick TG, Tosakulwong N, Bailey KR, Fields JA, Shuster LT, Zuk SM, Senjem ML, Mielke MM, Gleason C, Jack CR, Rocca WA, Miller VM.

J Alzheimers Dis. 2016 May 7;53(2):547-56. doi: 10.3233/JAD-160258.


When Lowest Dose for Shortest Amount of Time Does Not Apply.

Faubion SS, Files JA, Rocca WA.

J Womens Health (Larchmt). 2016 Apr;25(4):416-7. doi: 10.1089/jwh.2016.5781. Epub 2016 Mar 30. No abstract available.


Improvement in Cardiovascular Risk Prediction with Electronic Health Records.

Pike MM, Decker PA, Larson NB, St Sauver JL, Takahashi PY, Roger VL, Rocca WA, Miller VM, Olson JE, Pathak J, Bielinski SJ.

J Cardiovasc Transl Res. 2016 Jun;9(3):214-22. doi: 10.1007/s12265-016-9687-z. Epub 2016 Mar 9.


Prevalence of Combined Somatic and Mental Health Multimorbidity: Patterns by Age, Sex, and Race/Ethnicity.

Bobo WV, Yawn BP, St Sauver JL, Grossardt BR, Boyd CM, Rocca WA.

J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1483-1491. Epub 2016 Mar 2.


Jack P. Whisnant, MD, FAAN (1924–2015).

Brown RD Jr, Rocca WA.

Neurology. 2015 Nov 24;85(21):1832-3. No abstract available.


Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR Jr.

Neurology. 2016 Mar 22;86(12):1128-35. doi: 10.1212/WNL.0000000000002490. Epub 2016 Feb 24.


Long-term risk of myocardial infarction and stroke in bipolar I disorder: A population-based Cohort Study.

Prieto ML, Schenck LA, Kruse JL, Klaas JP, Chamberlain AM, Bobo WV, Bellivier F, Leboyer M, Roger VL, Brown RD Jr, Rocca WA, Frye MA.

J Affect Disord. 2016 Apr;194:120-7. doi: 10.1016/j.jad.2016.01.015. Epub 2016 Jan 13.


Elective Oophorectomy: Primum Non Nocere.

Faubion SS, Files JA, Rocca WA.

J Womens Health (Larchmt). 2016 Feb;25(2):200-2. doi: 10.1089/jwh.2015.5656. Epub 2016 Jan 7. No abstract available.


Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study.

Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC.

Lancet Neurol. 2016 Jan;15(1):56-64. doi: 10.1016/S1474-4422(15)00323-3. Epub 2015 Nov 18.


Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community.

Petersen RC, Wiste HJ, Weigand SD, Rocca WA, Roberts RO, Mielke MM, Lowe VJ, Knopman DS, Pankratz VS, Machulda MM, Geda YE, Jack CR Jr.

JAMA Neurol. 2016 Jan;73(1):85-92. doi: 10.1001/jamaneurol.2015.3098. Erratum in: JAMA Neurol. 2016 Apr;73(4):481.


Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging.

Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, Wolf PA, Seshadri S, Petersen RC.

Neurology. 2015 Nov 10;85(19):1712-21. doi: 10.1212/WNL.0000000000002100. Epub 2015 Oct 9. Review.


Sex Differences Research, Precision Medicine, and the Future of Women's Health.

Miller VM, Rocca WA, Faubion SS.

J Womens Health (Larchmt). 2015 Dec;24(12):969-71. doi: 10.1089/jwh.2015.5498. Epub 2015 Sep 1.


Cardiovascular risk factors and diseases in women undergoing hysterectomy with ovarian conservation.

Laughlin-Tommaso SK, Khan Z, Weaver AL, Schleck CD, Rocca WA, Stewart EA.

Menopause. 2016 Feb;23(2):121-8. doi: 10.1097/GME.0000000000000506.

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