Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 118

1.

YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling.

Kegelman CD, Coulombe JC, Jordan KM, Horan DJ, Qin L, Robling AG, Ferguson VL, Bellido TM, Boerckel JD.

J Bone Miner Res. 2019 Oct 14. doi: 10.1002/jbmr.3876. [Epub ahead of print]

PMID:
31610061
2.

Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo.

Bullock WA, Hoggatt AM, Horan DJ, Elmendorf AJ, Sato AY, Bellido T, Loots GG, Pavalko FM, Robling AG.

iScience. 2019 Sep 18;20:205-215. doi: 10.1016/j.isci.2019.09.023. [Epub ahead of print]

3.

Skeletal adaptations in young male mice after 4 weeks aboard the International Space Station.

Maupin KA, Childress P, Brinker A, Khan F, Abeysekera I, Aguilar IN, Olivos DJ 3rd, Adam G, Savaglio MK, Ganesh V, Gorden R, Mannfeld R, Beckner E, Horan DJ, Robling AG, Chakraborty N, Gautam A, Hammamieh R, Kacena MA.

NPJ Microgravity. 2019 Sep 24;5:21. doi: 10.1038/s41526-019-0081-4. eCollection 2019.

4.

Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization.

Lewis KJ, Choi RB, Pemberton EZ, Bullock WA, Firulli AB, Robling AG.

Int J Mol Sci. 2019 Sep 9;20(18). pii: E4427. doi: 10.3390/ijms20184427.

5.

Expression of a Degradation-Resistant β-Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation-Induced Bone Wasting.

Bullock WA, Hoggatt AM, Horan DJ, Lewis KJ, Yokota H, Hann S, Warman ML, Sebastian A, Loots GG, Pavalko FM, Robling AG.

J Bone Miner Res. 2019 Jun 7. doi: 10.1002/jbmr.3812. [Epub ahead of print]

PMID:
31173667
6.

Osteocytes and mechanical loading: The Wnt connection.

Bullock WA, Pavalko FM, Robling AG.

Orthod Craniofac Res. 2019 May;22 Suppl 1:175-179. doi: 10.1111/ocr.12282.

PMID:
31074153
7.

Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth.

Mathis NJ, Adaniya EN, Smith LM, Robling AG, Jepsen KJ, Schlecht SH.

PLoS One. 2019 Apr 4;14(4):e0214520. doi: 10.1371/journal.pone.0214520. eCollection 2019.

8.

Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality.

Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E749-E772. doi: 10.1152/ajpendo.00343.2018. Epub 2019 Jan 15.

PMID:
30645175
9.

Finite Element Analysis of the Mouse Distal Femur with Tumor Burden in Response to Knee Loading.

Jiang F, Liu S, Chen A, Li BY, Robling AG, Chen J, Yokota H.

Int J Orthop (Hong Kong). 2018;5(1):863-871. Epub 2018 Feb 28.

10.

Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.

Kang KS, Hong JM, Horan DJ, Lim KE, Bullock WA, Bruzzaniti A, Hann S, Warman ML, Robling AG.

Bone. 2019 Mar;120:166-175. doi: 10.1016/j.bone.2018.10.007. Epub 2018 Oct 25.

PMID:
30409757
11.

Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects.

Loots GG, Robling AG, Chang JC, Murugesh DK, Bajwa J, Carlisle C, Manilay JO, Wong A, Yellowley CE, Genetos DC.

Bone. 2018 Nov;116:307-314. doi: 10.1016/j.bone.2018.08.022. Epub 2018 Aug 30.

PMID:
30172741
12.

Finite-element analysis of the mouse proximal ulna in response to elbow loading.

Jiang F, Jalali A, Deguchi C, Chen A, Liu S, Kondo R, Minami K, Horiuchi T, Li BY, Robling AG, Chen J, Yokota H.

J Bone Miner Metab. 2019 May;37(3):419-429. doi: 10.1007/s00774-018-0943-y. Epub 2018 Jul 30.

PMID:
30062431
13.

Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition.

Witcher PC, Miner SE, Horan DJ, Bullock WA, Lim KE, Kang KS, Adaniya AL, Ross RD, Loots GG, Robling AG.

JCI Insight. 2018 Jun 7;3(11). pii: 98673. doi: 10.1172/jci.insight.98673. eCollection 2018 Jun 7.

14.

Conditional Deletion of Sost in MSC-Derived Lineages Identifies Specific Cell-Type Contributions to Bone Mass and B-Cell Development.

Yee CS, Manilay JO, Chang JC, Hum NR, Murugesh DK, Bajwa J, Mendez ME, Economides AE, Horan DJ, Robling AG, Loots GG.

J Bone Miner Res. 2018 Oct;33(10):1748-1759. doi: 10.1002/jbmr.3467. Epub 2018 Jun 29.

15.

Skeletal cell YAP and TAZ combinatorially promote bone development.

Kegelman CD, Mason DE, Dawahare JH, Horan DJ, Vigil GD, Howard SS, Robling AG, Bellido TM, Boerckel JD.

FASEB J. 2018 May;32(5):2706-2721. doi: 10.1096/fj.201700872R. Epub 2018 Jan 10.

16.

Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification.

Williams JN, Kambrath AV, Patel RB, Kang KS, Mével E, Li Y, Cheng YH, Pucylowski AJ, Hassert MA, Voor MJ, Kacena MA, Thompson WR, Warden SJ, Burr DB, Allen MR, Robling AG, Sankar U.

J Bone Miner Res. 2018 May;33(5):930-944. doi: 10.1002/jbmr.3379. Epub 2018 Feb 5.

17.

The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects.

Bird IM, Kim SH, Schweppe DK, Caetano-Lopes J, Robling AG, Charles JF, Gygi SP, Warman ML, Smits PJ.

Development. 2018 Jan 8;145(1). pii: dev156588. doi: 10.1242/dev.156588.

18.

Loss of mechanosensitive sclerostin may accelerate cranial bone growth and regeneration.

Kang KS, Lastfogel J, Ackerman LL, Jea A, Robling AG, Tholpady SS.

J Neurosurg. 2018 Oct;129(4):1085-1091. doi: 10.3171/2017.5.JNS17219. Epub 2017 Nov 10.

PMID:
29125417
19.

WNT-mediated Modulation of Bone Metabolism: Implications for WNT Targeting to Treat Extraskeletal Disorders.

Bullock WA, Robling AG.

Toxicol Pathol. 2017 Oct;45(7):864-868. doi: 10.1177/0192623317738170. Epub 2017 Nov 5.

20.

Clcn7F318L/+ as a new mouse model of Albers-Schönberg disease.

Caetano-Lopes J, Lessard SG, Hann S, Espinoza K, Kang KS, Lim KE, Horan DJ, Noonan HR, Hu D, Baron R, Robling AG, Warman ML.

Bone. 2017 Dec;105:253-261. doi: 10.1016/j.bone.2017.09.007. Epub 2017 Sep 20.

21.

Old age causes de novo intracortical bone remodeling and porosity in mice.

Piemontese M, Almeida M, Robling AG, Kim HN, Xiong J, Thostenson JD, Weinstein RS, Manolagas SC, O'Brien CA, Jilka RL.

JCI Insight. 2017 Sep 7;2(17). pii: 93771. doi: 10.1172/jci.insight.93771. eCollection 2017 Sep 7.

22.

Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism.

Shao Y, Hernandez-Buquer S, Childress P, Stayrook KR, Alvarez MB, Davis H, Plotkin LI, He Y, Condon KW, Burr DB, Warden SJ, Robling AG, Yang FC, Wek RC, Allen MR, Bidwell JP.

Endocrinology. 2017 Sep 1;158(9):2722-2740. doi: 10.1210/en.2017-00355.

23.

Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis.

Firulli BA, Milliar H, Toolan KP, Harkin J, Fuchs RK, Robling AG, Firulli AB.

Development. 2017 Jul 1;144(13):2480-2489. doi: 10.1242/dev.149963. Epub 2017 Jun 2.

24.

Quick and inexpensive paraffin-embedding method for dynamic bone formation analyses.

Porter A, Irwin R, Miller J, Horan DJ, Robling AG, McCabe LR.

Sci Rep. 2017 Feb 15;7:42505. doi: 10.1038/srep42505.

25.

Differential Bone Loss in Mouse Models of Colon Cancer Cachexia.

Bonetto A, Kays JK, Parker VA, Matthews RR, Barreto R, Puppa MJ, Kang KS, Carson JA, Guise TA, Mohammad KS, Robling AG, Couch ME, Koniaris LG, Zimmers TA.

Front Physiol. 2017 Jan 11;7:679. doi: 10.3389/fphys.2016.00679. eCollection 2016.

26.

Sclerostin: From bedside to bench, and back to bedside.

Robling AG, Drake MT, Papapoulos SE.

Bone. 2017 Mar;96:1-2. doi: 10.1016/j.bone.2017.01.019. Epub 2017 Jan 20. No abstract available.

PMID:
28115280
27.

Bone Mass and Strength are Significantly Improved in Mice Overexpressing Human WNT16 in Osteocytes.

Alam I, Reilly AM, Alkhouli M, Gerard-O'Riley RL, Kasipathi C, Oakes DK, Wright WB, Acton D, McQueen AK, Patel B, Lim KE, Robling AG, Econs MJ.

Calcif Tissue Int. 2017 Apr;100(4):361-373. doi: 10.1007/s00223-016-0225-4. Epub 2016 Dec 24.

28.

Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation.

Robling AG, Kang KS, Bullock WA, Foster WH, Murugesh D, Loots GG, Genetos DC.

Bone. 2016 Nov;92:180-188. doi: 10.1016/j.bone.2016.09.001. Epub 2016 Sep 4.

29.

Enhanced Wnt signaling improves bone mass and strength, but not brittleness, in the Col1a1(+/mov13) mouse model of type I Osteogenesis Imperfecta.

Jacobsen CM, Schwartz MA, Roberts HJ, Lim KE, Spevak L, Boskey AL, Zurakowski D, Robling AG, Warman ML.

Bone. 2016 Sep;90:127-32. doi: 10.1016/j.bone.2016.06.005. Epub 2016 Jun 11.

30.

Adult-Onset Deletion of β-Catenin in (10kb)Dmp1-Expressing Cells Prevents Intermittent PTH-Induced Bone Gain.

Kedlaya R, Kang KS, Hong JM, Bettagere V, Lim KE, Horan D, Divieti-Pajevic P, Robling AG.

Endocrinology. 2016 Aug;157(8):3047-57. doi: 10.1210/en.2015-1587. Epub 2016 Jun 2.

31.
32.

Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.

Collette NM, Yee CS, Hum NR, Murugesh DK, Christiansen BA, Xie L, Economides AN, Manilay JO, Robling AG, Loots GG.

Bone. 2016 Jul;88:20-30. doi: 10.1016/j.bone.2016.04.005. Epub 2016 Apr 19.

33.

Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice.

Alam I, Alkhouli M, Gerard-O'Riley RL, Wright WB, Acton D, Gray AK, Patel B, Reilly AM, Lim KE, Robling AG, Econs MJ.

Endocrinology. 2016 Feb;157(2):722-36. doi: 10.1210/en.2015-1281. Epub 2015 Nov 19.

34.

Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia.

Niziolek PJ, Bullock W, Warman ML, Robling AG.

PLoS One. 2015 Nov 10;10(11):e0140775. doi: 10.1371/journal.pone.0140775. eCollection 2015.

35.

Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status.

Ross RD, Mashiatulla M, Robling AG, Miller LM, Sumner DR.

Calcif Tissue Int. 2016 Feb;98(2):149-57. doi: 10.1007/s00223-015-0074-6. Epub 2015 Oct 29.

PMID:
26514840
36.

Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.

Goodman CA, Hornberger TA, Robling AG.

Bone. 2015 Nov;80:24-36. doi: 10.1016/j.bone.2015.04.014. Review.

37.

Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.

Childress P, Stayrook KR, Alvarez MB, Wang Z, Shao Y, Hernandez-Buquer S, Mack JK, Grese ZR, He Y, Horan D, Pavalko FM, Warden SJ, Robling AG, Yang FC, Allen MR, Krishnan V, Liu Y, Bidwell JP.

Mol Endocrinol. 2015 Sep;29(9):1269-85. doi: 10.1210/me.2014-1406. Epub 2015 Aug 5.

38.

High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.

Niziolek PJ, MacDonald BT, Kedlaya R, Zhang M, Bellido T, He X, Warman ML, Robling AG.

J Bone Miner Res. 2015 Oct;30(10):1822-30. doi: 10.1002/jbmr.2514.

39.

Development of an in vivo rabbit ulnar loading model.

Baumann AP, Aref MW, Turnbull TL, Robling AG, Niebur GL, Allen MR, Roeder RK.

Bone. 2015 Jun;75:55-61. doi: 10.1016/j.bone.2015.01.022. Epub 2015 Feb 12.

PMID:
25683214
40.

New Insights into Wnt-Lrp5/6-β-Catenin Signaling in Mechanotransduction.

Kang KS, Robling AG.

Front Endocrinol (Lausanne). 2015 Jan 20;5:246. doi: 10.3389/fendo.2014.00246. eCollection 2014. Review.

41.

Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.

Cui Y, Niziolek PJ, MacDonald BT, Alenina N, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Powell DR, He X, Bader M, Williams BO, Warman ML, Robling AG.

Nat Med. 2014 Nov;20(11):1229-30. doi: 10.1038/nm.3697. No abstract available.

42.

In vivo axial loading of the mouse tibia.

Melville KM, Robling AG, van der Meulen MC.

Methods Mol Biol. 2015;1226:99-115. doi: 10.1007/978-1-4939-1619-1_9.

43.

Targeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta.

Jacobsen CM, Barber LA, Ayturk UM, Roberts HJ, Deal LE, Schwartz MA, Weis M, Eyre D, Zurakowski D, Robling AG, Warman ML.

J Bone Miner Res. 2014 Oct;29(10):2297-306. doi: 10.1002/jbmr.2198.

44.

Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome.

Kedlaya R, Veera S, Horan DJ, Moss RE, Ayturk UM, Jacobsen CM, Bowen ME, Paszty C, Warman ML, Robling AG.

Sci Transl Med. 2013 Nov 13;5(211):211ra158. doi: 10.1126/scitranslmed.3006627.

45.

Mechanosignaling in bone health, trauma and inflammation.

Knapik DM, Perera P, Nam J, Blazek AD, Rath B, Leblebicioglu B, Das H, Wu LC, Hewett TE, Agarwal SK Jr, Robling AG, Flanigan DC, Lee BS, Agarwal S.

Antioxid Redox Signal. 2014 Feb 20;20(6):970-85. doi: 10.1089/ars.2013.5467. Epub 2013 Aug 12. Review.

46.

An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.

Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML.

J Bone Miner Res. 2013 Oct;28(10):2081-93. doi: 10.1002/jbmr.1946.

47.

The expanding role of Wnt signaling in bone metabolism.

Robling AG.

Bone. 2013 Jul;55(1):256-7. doi: 10.1016/j.bone.2013.03.001. Epub 2013 Mar 14. No abstract available.

48.

Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice.

Bivi N, Pacheco-Costa R, Brun LR, Murphy TR, Farlow NR, Robling AG, Bellido T, Plotkin LI.

J Orthop Res. 2013 Jul;31(7):1075-81. doi: 10.1002/jor.22341. Epub 2013 Mar 11.

49.

Reduced gravitational loading does not account for the skeletal effect of botulinum toxin-induced muscle inhibition suggesting a direct effect of muscle on bone.

Warden SJ, Galley MR, Richard JS, George LA, Dirks RC, Guildenbecher EA, Judd AM, Robling AG, Fuchs RK.

Bone. 2013 May;54(1):98-105. doi: 10.1016/j.bone.2013.01.043. Epub 2013 Feb 4.

50.

Inactivation of Lrp5 in osteocytes reduces young's modulus and responsiveness to the mechanical loading.

Zhao L, Shim JW, Dodge TR, Robling AG, Yokota H.

Bone. 2013 May;54(1):35-43. doi: 10.1016/j.bone.2013.01.033. Epub 2013 Jan 26.

Supplemental Content

Loading ...
Support Center