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Items: 23


Sleep-wake cycles drive daily dynamics of synaptic phosphorylation.

Brüning F, Noya SB, Bange T, Koutsouli S, Rudolph JD, Tyagarajan SK, Cox J, Mann M, Brown SA, Robles MS.

Science. 2019 Oct 11;366(6462). pii: eaav3617. doi: 10.1126/science.aav3617.


The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep.

Noya SB, Colameo D, Brüning F, Spinnler A, Mircsof D, Opitz L, Mann M, Tyagarajan SK, Robles MS, Brown SA.

Science. 2019 Oct 11;366(6462). pii: eaav2642. doi: 10.1126/science.aav2642.


A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling.

Harpprecht L, Baldi S, Schauer T, Schmidt A, Bange T, Robles MS, Kremmer E, Imhof A, Becker PB.

Nucleic Acids Res. 2019 Aug 22;47(14):7444-7459. doi: 10.1093/nar/gkz473.


Obesity is a significant risk factor for ileostomy site incisional hernia following reversal.

De Robles MS, Bakhtiar A, Young CJ.

ANZ J Surg. 2019 Apr;89(4):399-402. doi: 10.1111/ans.14983. Epub 2019 Jan 26.


Colonic lymphangioma presenting with intermittent pain and intussusception.

Ly MMG, De Robles MS, Mckenzie C, Young CJ.

J Surg Case Rep. 2019 Jan 11;2019(1):rjy336. doi: 10.1093/jscr/rjy336. eCollection 2019 Jan.


Rubber Band Ligation of Hemorrhoids is often a Necessary Complement in the Management of Hemorrhagic Radiation Proctitis.

De Robles MS, Young CJ.

Scand J Surg. 2019 Jan 11:1457496918822619. doi: 10.1177/1457496918822619. [Epub ahead of print]


Karydakis procedure can be effectively performed in the lateral position.

De Robles MS, Seyfi D, Zahid A, Young CJ.

ANZ J Surg. 2019 Jan;89(1-2):E10-E14. doi: 10.1111/ans.14844. Epub 2018 Sep 21.


The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization.

Korge S, Maier B, Brüning F, Ehrhardt L, Korte T, Mann M, Herrmann A, Robles MS, Kramer A.

PLoS Genet. 2018 Jan 29;14(1):e1007189. doi: 10.1371/journal.pgen.1007189. eCollection 2018 Jan.


Guidelines for Genome-Scale Analysis of Biological Rhythms.

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB.

J Biol Rhythms. 2017 Oct;32(5):380-393. doi: 10.1177/0748730417728663. Epub 2017 Nov 3.


Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology.

Robles MS, Humphrey SJ, Mann M.

Cell Metab. 2017 Jan 10;25(1):118-127. doi: 10.1016/j.cmet.2016.10.004. Epub 2016 Nov 3.


Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins.

Neufeld-Cohen A, Robles MS, Aviram R, Manella G, Adamovich Y, Ladeuix B, Nir D, Rousso-Noori L, Kuperman Y, Golik M, Mann M, Asher G.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1673-82. doi: 10.1073/pnas.1519650113. Epub 2016 Feb 9.


Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.

Tamayo AG, Duong HA, Robles MS, Mann M, Weitz CJ.

Nat Struct Mol Biol. 2015 Oct;22(10):759-66. doi: 10.1038/nsmb.3076. Epub 2015 Aug 31.


In-vivo quantitative proteomics reveals a key contribution of post-transcriptional mechanisms to the circadian regulation of liver metabolism.

Robles MS, Cox J, Mann M.

PLoS Genet. 2014 Jan;10(1):e1004047. doi: 10.1371/journal.pgen.1004047. Epub 2014 Jan 2.


Proteomic approaches in circadian biology.

Robles MS, Mann M.

Handb Exp Pharmacol. 2013;(217):389-407. doi: 10.1007/978-3-642-25950-0_17. Review.


Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex.

Padmanabhan K, Robles MS, Westerling T, Weitz CJ.

Science. 2012 Aug 3;337(6094):599-602. doi: 10.1126/science.1221592. Epub 2012 Jul 5.


A molecular mechanism for circadian clock negative feedback.

Duong HA, Robles MS, Knutti D, Weitz CJ.

Science. 2011 Jun 17;332(6036):1436-9. doi: 10.1126/science.1196766.


Identification of RACK1 and protein kinase Calpha as integral components of the mammalian circadian clock.

Robles MS, Boyault C, Knutti D, Padmanabhan K, Weitz CJ.

Science. 2010 Jan 22;327(5964):463-6. doi: 10.1126/science.1180067.


Exacerbated inflammatory responses in transgenic mice expressing an inhibitor of apoptosis protein (OpIAP).

Robles MS, Leonardo E, Criado LM, Izquierdo M, Martínez-A C.

Cell Death Differ. 2003 Nov;10(11):1226-33.


Cell death during lymphocyte development and activation.

de Alborán IM, Robles MS, Bras A, Baena E, Martínez-A C.

Semin Immunol. 2003 Jun;15(3):125-33. Review.


Degradation of cellular mRNA is a general early apoptosis-induced event.

Del Prete MJ, Robles MS, Guáo A, Martínez-A C, Izquierdo M, Garcia-Sanz JA.

FASEB J. 2002 Dec;16(14):2003-5. Epub 2002 Oct 18.


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