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Items: 1 to 50 of 221

1.

Remote Activation of a Latent Epitope in an Autoantigen Decoded With Simulated B-Factors.

Pang YP, Casal Moura M, Thompson GE, Nelson DR, Hummel AM, Jenne DE, Emerling D, Volkmuth W, Robinson WH, Specks U.

Front Immunol. 2019 Oct 25;10:2467. doi: 10.3389/fimmu.2019.02467. eCollection 2019.

2.

Immunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune disease.

Murphy KA, Bhamidipati K, Rubin SJS, Kipp L, Robinson WH, Lanz TV.

Clin Immunol. 2019 Oct 25;209:108276. doi: 10.1016/j.clim.2019.108276. [Epub ahead of print]

PMID:
31669582
3.

Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis.

Wang Q, Onuma K, Liu C, Wong H, Bloom MS, Elliott EE, Cao RR, Hu N, Lingampalli N, Sharpe O, Zhao X, Sohn DH, Lepus CM, Sokolove J, Mao R, Cisar CT, Raghu H, Chu CR, Giori NJ, Willingham SB, Prohaska SS, Cheng Z, Weissman IL, Robinson WH.

JCI Insight. 2019 Sep 19;4(18). pii: 128616. doi: 10.1172/jci.insight.128616.

4.

Autoantibodies to protein-arginine deiminase (PAD) 4 in rheumatoid arthritis: immunological and clinical significance, and potential for precision medicine.

Martinez-Prat L, Palterer B, Vitiello G, Parronchi P, Robinson WH, Mahler M.

Expert Rev Clin Immunol. 2019 Oct;15(10):1073-1087. doi: 10.1080/1744666X.2020.1668778. Epub 2019 Oct 13.

PMID:
31524005
5.

Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.

Byrd AS, Carmona-Rivera C, O'Neil LJ, Carlucci PM, Cisar C, Rosenberg AZ, Kerns ML, Caffrey JA, Milner SM, Sacks JM, Aliu O, Broderick KP, Reichner JS, Miller LS, Kang S, Robinson WH, Okoye GA, Kaplan MJ.

Sci Transl Med. 2019 Sep 4;11(508). pii: eaav5908. doi: 10.1126/scitranslmed.aav5908.

PMID:
31484788
6.

Antigen-specific tolerance to self-antigens in protein replacement therapy, gene therapy and autoimmunity.

Steinman L, Ho PP, Robinson WH, Utz PJ, Villoslada P.

Curr Opin Immunol. 2019 Aug 30;61:46-53. doi: 10.1016/j.coi.2019.07.011. [Epub ahead of print] Review.

PMID:
31476445
7.

Paraneoplastic and Therapy-Related Immune Complications in Thymic Malignancies.

Lippner EA, Lewis DB, Robinson WH, Katsumoto TR.

Curr Treat Options Oncol. 2019 Jun 22;20(7):62. doi: 10.1007/s11864-019-0661-2. Review.

PMID:
31227926
8.

IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis.

Wang Q, Lepus CM, Raghu H, Reber LL, Tsai MM, Wong HH, von Kaeppler E, Lingampalli N, Bloom MS, Hu N, Elliott EE, Oliviero F, Punzi L, Giori NJ, Goodman SB, Chu CR, Sokolove J, Fukuoka Y, Schwartz LB, Galli SJ, Robinson WH.

Elife. 2019 May 14;8. pii: e39905. doi: 10.7554/eLife.39905.

9.

Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation.

O'Donnell C, Migliore E, Grandi FC, Koltsov J, Lingampalli N, Cisar C, Indelli PF, Sebastiano V, Robinson WH, Bhutani N, Chu CR.

J Orthop Res. 2019 May 1. doi: 10.1002/jor.24322. [Epub ahead of print]

PMID:
31042308
10.

B cell checkpoints in autoimmune rheumatic diseases.

Rubin SJS, Bloom MS, Robinson WH.

Nat Rev Rheumatol. 2019 May;15(5):303-315. doi: 10.1038/s41584-019-0211-0. Review.

PMID:
30967621
11.

Prefoldin 5 and Anti-prefoldin 5 Antibodies as Biomarkers for Uveitis in Ankylosing Spondylitis.

Kwon OC, Lee EJ, Lee JY, Youn J, Kim TH, Hong S, Lee CK, Yoo B, Robinson WH, Kim YG.

Front Immunol. 2019 Mar 5;10:384. doi: 10.3389/fimmu.2019.00384. eCollection 2019.

12.

Exogenous micro-RNA and antagomir modulate osteogenic gene expression in tenocytes.

Xiao M, Iglinski-Benjamin KC, Sharpe O, Robinson WH, Abrams GD.

Exp Cell Res. 2019 May 15;378(2):119-123. doi: 10.1016/j.yexcr.2019.03.008. Epub 2019 Mar 5.

PMID:
30849310
13.

Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Patients With Rheumatoid Arthritis in Clinical Remission.

Orange DE, Agius P, DiCarlo EF, Mirza SZ, Pannellini T, Szymonifka J, Jiang CS, Figgie MP, Frank MO, Robinson WH, Donlin LT, Rozo C, Gravallese EM, Bykerk VP, Goodman SM.

Arthritis Rheumatol. 2019 Jul;71(7):1034-1041. doi: 10.1002/art.40878. Epub 2019 Jun 5.

PMID:
30835943
14.

Affinity Maturation of the Anti-Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis.

Kongpachith S, Lingampalli N, Ju CH, Blum LK, Lu DR, Elliott SE, Mao R, Robinson WH.

Arthritis Rheumatol. 2019 Apr;71(4):507-517. doi: 10.1002/art.40760. Epub 2019 Feb 27.

PMID:
30811898
15.

Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension.

Sweatt AJ, Hedlin HK, Balasubramanian V, Hsi A, Blum LK, Robinson WH, Haddad F, Hickey PM, Condliffe R, Lawrie A, Nicolls MR, Rabinovitch M, Khatri P, Zamanian RT.

Circ Res. 2019 Mar 15;124(6):904-919. doi: 10.1161/CIRCRESAHA.118.313911.

16.

Higher C6 enzyme immunoassay index values correlate with a diagnosis of noncutaneous Lyme disease.

Nigrovic LE, Lipsett SC, Molins CR, Wormser GP, Bennett JE, Garro AC, Levas MN, Balamuth F, Neville D, Lingampalli N, Robinson WH, Branda JA.

Diagn Microbiol Infect Dis. 2019 Jun;94(2):160-164. doi: 10.1016/j.diagmicrobio.2018.12.001. Epub 2018 Dec 8.

PMID:
30642722
17.

Direct Diagnostic Tests for Lyme Disease.

Schutzer SE, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder JL, Steere AC, Witkowski J, Wong SJ, Branda JA.

Clin Infect Dis. 2019 Mar 5;68(6):1052-1057. doi: 10.1093/cid/ciy614.

18.

Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy.

Ho PP, Lahey LJ, Mourkioti F, Kraft PE, Filareto A, Brandt M, Magnusson KEG, Finn EE, Chamberlain JS, Robinson WH, Blau HM, Steinman L.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9182-E9191. doi: 10.1073/pnas.1808648115. Epub 2018 Sep 4.

19.

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.

Holers VM, Demoruelle MK, Kuhn KA, Buckner JH, Robinson WH, Okamoto Y, Norris JM, Deane KD.

Nat Rev Rheumatol. 2018 Sep;14(9):542-557. doi: 10.1038/s41584-018-0070-0. Review.

20.

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease.

Blum LK, Adamska JZ, Martin DS, Rebman AW, Elliott SE, Cao RRL, Embers ME, Aucott JN, Soloski MJ, Robinson WH.

Front Immunol. 2018 Jul 18;9:1634. doi: 10.3389/fimmu.2018.01634. eCollection 2018.

21.

Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, Eisenhaure TM, Li S, Browne EP, Chicoine A, Sutherby D, Noma A; Accelerating Medicines Partnership RA/SLE Network, Nusbaum C, Kelly S, Pernis AB, Ivashkiv LB, Goodman SM, Robinson WH, Utz PJ, Lederer JA, Gravallese EM, Boyce BF, Hacohen N, Pitzalis C, Gregersen PK, Firestein GS, Raychaudhuri S, Moreland LW, Holers VM, Bykerk VP, Filer A, Boyle DL, Brenner MB, Anolik JH.

Arthritis Res Ther. 2018 Jul 11;20(1):139. doi: 10.1186/s13075-018-1631-y.

22.

Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients.

Zhao L, Yamaguchi Y, Ge X, Robinson WH, Morser J, Leung LLK.

Arthritis Res Ther. 2018 Jul 4;20(1):132. doi: 10.1186/s13075-018-1615-y.

23.

Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients.

Hughes-Austin JM, Deane KD, Giles JT, Derber LA, Zerbe GO, Dabelea DM, Sokolove J, Robinson WH, Holers VM, Norris JM.

PLoS One. 2018 Jun 25;13(6):e0199578. doi: 10.1371/journal.pone.0199578. eCollection 2018.

24.

Affinity Maturation Drives Epitope Spreading and Generation of Proinflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.

Elliott SE, Kongpachith S, Lingampalli N, Adamska JZ, Cannon BJ, Mao R, Blum LK, Robinson WH.

Arthritis Rheumatol. 2018 Dec;70(12):1946-1958. doi: 10.1002/art.40587. Epub 2018 Oct 20.

PMID:
29927104
25.

T Cell-Dependent Affinity Maturation and Innate Immune Pathways Differentially Drive Autoreactive B Cell Responses in Rheumatoid Arthritis.

Lu DR, McDavid AN, Kongpachith S, Lingampalli N, Glanville J, Ju CH, Gottardo R, Robinson WH.

Arthritis Rheumatol. 2018 Nov;70(11):1732-1744. doi: 10.1002/art.40578. Epub 2018 Sep 24.

26.

Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more rapid progression from preclinical to clinical rheumatoid arthritis.

Lingampalli N, Sokolove J, Lahey LJ, Edison JD, Gilliland WR, Holers VM, Deane KD, Robinson WH.

Clin Immunol. 2018 Oct;195:119-126. doi: 10.1016/j.clim.2018.05.004. Epub 2018 May 26.

PMID:
29842946
27.

Revealing the specificity of regulatory T cells in murine autoimmune diabetes.

Spence A, Purtha W, Tam J, Dong S, Kim Y, Ju CH, Sterling T, Nakayama M, Robinson WH, Bluestone JA, Anderson MS, Tang Q.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5265-5270. doi: 10.1073/pnas.1715590115. Epub 2018 Apr 30. Erratum in: Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5634.

28.

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2018 Mar 30;3(21). pii: eaar3701. doi: 10.1126/sciimmunol.aar3701.

29.

Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data.

Orange DE, Agius P, DiCarlo EF, Robine N, Geiger H, Szymonifka J, McNamara M, Cummings R, Andersen KM, Mirza S, Figgie M, Ivashkiv LB, Pernis AB, Jiang CS, Frank MO, Darnell RB, Lingampali N, Robinson WH, Gravallese E; Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus Network, Bykerk VP, Goodman SM, Donlin LT.

Arthritis Rheumatol. 2018 May;70(5):690-701. doi: 10.1002/art.40428. Epub 2018 Apr 2.

30.

Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains.

Ju CH, Blum LK, Kongpachith S, Lingampalli N, Mao R, Brodin P, Dekker CL, Davis MM, Robinson WH.

Clin Immunol. 2018 Aug;193:70-79. doi: 10.1016/j.clim.2018.01.011. Epub 2018 Feb 2.

31.

Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.

Blum LK, Cao RRL, Sweatt AJ, Bill M, Lahey LJ, Hsi AC, Lee CS, Kongpachith S, Ju CH, Mao R, Wong HH, Nicolls MR, Zamanian RT, Robinson WH.

Eur J Immunol. 2018 May;48(5):874-884. doi: 10.1002/eji.201747460. Epub 2018 Feb 22.

32.

Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis.

Demoruelle MK, Bowers E, Lahey LJ, Sokolove J, Purmalek M, Seto NL, Weisman MH, Norris JM, Kaplan MJ, Holers VM, Robinson WH, Deane KD.

Arthritis Rheumatol. 2018 Apr;70(4):516-527. doi: 10.1002/art.40401. Epub 2018 Mar 2.

33.

Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis.

Hughes-Austin JM, Gan RW, Deane KD, Weisman MH, Demoruelle MK, Sokolove J, Robinson WH, Holers VM, Norris JM, Ix JH.

Am J Nephrol. 2017;46(6):481-487. doi: 10.1159/000485259. Epub 2017 Dec 13.

34.

Advances in Serodiagnostic Testing for Lyme Disease Are at Hand.

Branda JA, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder J, Steere AC, Witkowski J, Wong SJ, Schutzer SE.

Clin Infect Dis. 2018 Mar 19;66(7):1133-1139. doi: 10.1093/cid/cix943.

35.

Men and Women Differ in the Biochemical Composition of Platelet-Rich Plasma.

Xiong G, Lingampalli N, Koltsov JCB, Leung LL, Bhutani N, Robinson WH, Chu CR.

Am J Sports Med. 2018 Feb;46(2):409-419. doi: 10.1177/0363546517740845. Epub 2017 Dec 6.

PMID:
29211968
36.

Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.

DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH.

Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12.

37.

The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice.

Reber LL, Starkl P, Balbino B, Sibilano R, Gaudenzio N, Rogalla S, Sensarn S, Kang D, Raghu H, Sokolove J, Robinson WH, Contag CH, Tsai M, Galli SJ.

PLoS One. 2017 Oct 5;12(10):e0185704. doi: 10.1371/journal.pone.0185704. eCollection 2017.

38.

Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint.

Mikuls TR, Duryee MJ, Rahman R, Anderson DR, Sayles HR, Hollins A, Michaud K, Wolfe F, Thiele GE, Sokolove J, Robinson WH, Lingampalli N, Nicholas AP, Talmon GA, Su K, Zimmerman MC, Klassen LW, Thiele GM.

Rheumatology (Oxford). 2017 Oct 1;56(10):1794-1803. doi: 10.1093/rheumatology/kex212.

39.

Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.

Saito T, Miyagawa K, Chen SY, Tamosiuniene R, Wang L, Sharpe O, Samayoa E, Harada D, Moonen JAJ, Cao A, Chen PI, Hennigs JK, Gu M, Li CG, Leib RD, Li D, Adams CM, Del Rosario PA, Bill M, Haddad F, Montoya JG, Robinson WH, Fantl WJ, Nolan GP, Zamanian RT, Nicolls MR, Chiu CY, Ariza ME, Rabinovitch M.

Circulation. 2017 Nov 14;136(20):1920-1935. doi: 10.1161/CIRCULATIONAHA.117.027589. Epub 2017 Sep 21.

40.

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2017 Apr;2(10). pii: eaag3358. doi: 10.1126/sciimmunol.aag3358. Epub 2017 Apr 14.

41.

VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans.

Nair N, Feng N, Blum LK, Sanyal M, Ding S, Jiang B, Sen A, Morton JM, He XS, Robinson WH, Greenberg HB.

Sci Transl Med. 2017 Jun 21;9(395). pii: eaam5434. doi: 10.1126/scitranslmed.aam5434.

42.

Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study.

Birru Talabi M, Mackey RH, Kuller LH, Dorman JS, Deane KD, Robinson WH, Walitt BT, Chang Y, Holers VM, Liu S, Moreland LW.

Am J Epidemiol. 2017 Jul 15;186(2):245-254. doi: 10.1093/aje/kwx087.

43.

Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.

Willis VC, Banda NK, Cordova KN, Chandra PE, Robinson WH, Cooper DC, Lugo D, Mehta G, Taylor S, Tak PP, Prinjha RK, Lewis HD, Holers VM.

Clin Exp Immunol. 2017 May;188(2):263-274. doi: 10.1111/cei.12932. Epub 2017 Mar 9.

44.

Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis.

Lee J, Luria A, Rhodes C, Raghu H, Lingampalli N, Sharpe O, Rada B, Sohn DH, Robinson WH, Sokolove J.

Rheumatology (Oxford). 2017 Apr 1;56(4):644-653. doi: 10.1093/rheumatology/kew449.

45.

Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis.

Geraldino-Pardilla L, Russo C, Sokolove J, Robinson WH, Zartoshti A, Van Eyk J, Fert-Bober J, Lima J, Giles JT, Bathon JM.

Rheumatology (Oxford). 2017 Apr 1;56(4):534-540. doi: 10.1093/rheumatology/kew436.

46.

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis.

Raghu H, Lepus CM, Wang Q, Wong HH, Lingampalli N, Oliviero F, Punzi L, Giori NJ, Goodman SB, Chu CR, Sokolove JB, Robinson WH.

Ann Rheum Dis. 2017 May;76(5):914-922. doi: 10.1136/annrheumdis-2016-210426. Epub 2016 Dec 13.

47.

Elevated BMI and antibodies to citrullinated proteins interact to increase rheumatoid arthritis risk and shorten time to diagnosis: A nested case-control study of women in the Nurses' Health Studies.

Tedeschi SK, Cui J, Arkema EV, Robinson WH, Sokolove J, Lingampalli N, Sparks JA, Karlson EW, Costenbader KH.

Semin Arthritis Rheum. 2017 Jun;46(6):692-698. doi: 10.1016/j.semarthrit.2016.09.001. Epub 2016 Sep 13.

48.

Decreased Synovial Inflammation in Atraumatic Hip Microinstability Compared With Femoroacetabular Impingement.

Abrams GD, Luria A, Sampson J, Madding RA, Robinson WH, Safran MR, Sokolove J.

Arthroscopy. 2017 Mar;33(3):553-558. doi: 10.1016/j.arthro.2016.09.007. Epub 2016 Dec 8.

PMID:
27939067
49.

Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome.

Tajerian M, Hung V, Khan H, Lahey LJ, Sun Y, Birklein F, Krämer HH, Robinson WH, Kingery WS, Clark JD.

Exp Neurol. 2017 Jan;287(Pt 1):14-20. doi: 10.1016/j.expneurol.2016.10.011. Epub 2016 Oct 20.

50.

Association of Anti-Citrullinated Peptide Antibodies With Coronary Artery Calcification in Rheumatoid Arthritis.

Geraldino-Pardilla L, Giles JT, Sokolove J, Zartoshti A, Robinson WH, Budoff M, Detrano R, Bokhari S, Bathon JM.

Arthritis Care Res (Hoboken). 2017 Aug;69(8):1276-1281. doi: 10.1002/acr.23106. Epub 2017 Jul 10.

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