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Items: 1 to 50 of 445

1.

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry.

Chorev DS, Baker LA, Wu D, Beilsten-Edmands V, Rouse SL, Zeev-Ben-Mordehai T, Jiko C, Samsudin F, Gerle C, Khalid S, Stewart AG, Matthews SJ, Grünewald K, Robinson CV.

Science. 2018 Nov 16;362(6416):829-834. doi: 10.1126/science.aau0976.

PMID:
30442809
2.

Probing the Lipid Annular Belt by Gas-Phase Dissociation of Membrane Proteins in Nanodiscs.

Marty MT, Hoi KK, Gault J, Robinson CV.

Angew Chem Weinheim Bergstr Ger. 2016 Jan 11;128(2):560-564. doi: 10.1002/ange.201508289. Epub 2015 Nov 23.

3.

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.

Dong YY, Wang H, Pike ACW, Cochrane SA, Hamedzadeh S, Wyszyński FJ, Bushell SR, Royer SF, Widdick DA, Sajid A, Boshoff HI, Park Y, Lucas R, Liu WM, Lee SS, Machida T, Minall L, Mehmood S, Belaya K, Liu WW, Chu A, Shrestha L, Mukhopadhyay SMM, Strain-Damerell C, Chalk R, Burgess-Brown NA, Bibb MJ, Barry Iii CE, Robinson CV, Beeson D, Davis BG, Carpenter EP.

Cell. 2018 Nov 1;175(4):1045-1058.e16. doi: 10.1016/j.cell.2018.10.037.

4.

Genetic diversity and parasite facilitated establishment of the invasive signal crayfish (Pacifastacus leniusculus) in Great Britain.

Robinson CV, Garcia de Leaniz C, James J, Cable J, Orozco-terWengel P, Consuegra S.

Ecol Evol. 2018 Jul 30;8(18):9181-9191. doi: 10.1002/ece3.4235. eCollection 2018 Sep.

5.

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex.

Gong H, Li J, Xu A, Tang Y, Ji W, Gao R, Wang S, Yu L, Tian C, Li J, Yen HY, Man Lam S, Shui G, Yang X, Sun Y, Li X, Jia M, Yang C, Jiang B, Lou Z, Robinson CV, Wong LL, Guddat LW, Sun F, Wang Q, Rao Z.

Science. 2018 Oct 25. pii: eaat8923. doi: 10.1126/science.aat8923. [Epub ahead of print]

PMID:
30361386
6.

Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination.

Kecman T, Kuś K, Heo DH, Duckett K, Birot A, Liberatori S, Mohammed S, Geis-Asteggiante L, Robinson CV, Vasiljeva L.

Cell Rep. 2018 Oct 2;25(1):259-269.e5. doi: 10.1016/j.celrep.2018.09.007.

7.

Data on optimisation of a multiplex HRM-qPCR assay for native and invasive crayfish as well as the crayfish plague in four river catchments.

Robinson CV, Uren Webster TM, Consuegra S.

Data Brief. 2018 May 29;19:1092-1109. doi: 10.1016/j.dib.2018.05.134. eCollection 2018 Aug.

8.

N-glycan microheterogeneity regulates interactions of plasma proteins.

Wu D, Struwe WB, Harvey DJ, Ferguson MAJ, Robinson CV.

Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):8763-8768. doi: 10.1073/pnas.1807439115. Epub 2018 Aug 15.

9.

Self-assembly of toroidal proteins explored using native mass spectrometry.

Yewdall NA, Allison TM, Pearce FG, Robinson CV, Gerrard JA.

Chem Sci. 2018 Jun 18;9(28):6099-6106. doi: 10.1039/c8sc01379a. eCollection 2018 Jul 28.

10.

Author Correction: Structure of the core of the type III secretion system export apparatus.

Kuhlen L, Abrusci P, Johnson S, Gault J, Deme J, Caesar J, Dietsche T, Mebrhatu MT, Ganief T, Macek B, Wagner S, Robinson CV, Lea SM.

Nat Struct Mol Biol. 2018 Aug;25(8):743. doi: 10.1038/s41594-018-0095-8.

PMID:
30018321
11.

PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.

Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV.

Nature. 2018 Jul;559(7714):423-427. doi: 10.1038/s41586-018-0325-6. Epub 2018 Jul 11.

PMID:
29995853
12.

Structure of the core of the type III secretion system export apparatus.

Kuhlen L, Abrusci P, Johnson S, Gault J, Deme J, Caesar J, Dietsche T, Mebrhatu MT, Ganief T, Macek B, Wagner S, Robinson CV, Lea SM.

Nat Struct Mol Biol. 2018 Jul;25(7):583-590. doi: 10.1038/s41594-018-0086-9. Epub 2018 Jul 2. Erratum in: Nat Struct Mol Biol. 2018 Aug;25(8):743.

PMID:
29967543
13.

Lipid binding attenuates channel closure of the outer membrane protein OmpF.

Liko I, Degiacomi MT, Lee S, Newport TD, Gault J, Reading E, Hopper JTS, Housden NG, White P, Colledge M, Sula A, Wallace BA, Kleanthous C, Stansfeld PJ, Bayley H, Benesch JLP, Allison TM, Robinson CV.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6691-6696. doi: 10.1073/pnas.1721152115. Epub 2018 Jun 11.

14.

Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters.

Romano M, Fusco G, Choudhury HG, Mehmood S, Robinson CV, Zirah S, Hegemann JD, Lescop E, Marahiel MA, Rebuffat S, De Simone A, Beis K.

ACS Chem Biol. 2018 Jun 15;13(6):1598-1609. doi: 10.1021/acschembio.8b00226. Epub 2018 May 18.

15.

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M.

Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x.

16.

Identifying key membrane protein lipid interactions using mass spectrometry.

Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV.

Nat Protoc. 2018 May;13(5):1106-1120. doi: 10.1038/nprot.2018.014. Epub 2018 Apr 26.

17.

The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins.

Eaton JRO, Alenazi Y, Singh K, Davies G, Geis-Asteggiante L, Kessler B, Robinson CV, Kawamura A, Bhattacharya S.

J Biol Chem. 2018 Apr 20;293(16):6134-6146. doi: 10.1074/jbc.RA117.000487. Epub 2018 Feb 27.

18.

Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ.

Bolla JR, Sauer JB, Wu D, Mehmood S, Allison TM, Robinson CV.

Nat Chem. 2018 Mar;10(3):363-371. doi: 10.1038/nchem.2919. Epub 2018 Jan 8.

19.

Precursor-Receptor Interactions in the Twin Arginine Protein Transport Pathway Probed with a New Receptor Complex Preparation.

Wojnowska M, Gault J, Yong SC, Robinson CV, Berks BC.

Biochemistry. 2018 Mar 13;57(10):1663-1671. doi: 10.1021/acs.biochem.8b00026. Epub 2018 Feb 26.

20.

Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins.

Natan E, Endoh T, Haim-Vilmovsky L, Flock T, Chalancon G, Hopper JTS, Kintses B, Horvath P, Daruka L, Fekete G, Pál C, Papp B, Oszi E, Magyar Z, Marsh JA, Elcock AH, Babu MM, Robinson CV, Sugimoto N, Teichmann SA.

Nat Struct Mol Biol. 2018 Mar;25(3):279-288. doi: 10.1038/s41594-018-0029-5. Epub 2018 Feb 12.

21.

The structure of serum resistance-associated protein and its implications for human African trypanosomiasis.

Zoll S, Lane-Serff H, Mehmood S, Schneider J, Robinson CV, Carrington M, Higgins MK.

Nat Microbiol. 2018 Mar;3(3):295-301. doi: 10.1038/s41564-017-0085-3. Epub 2018 Jan 22.

PMID:
29358741
22.

Editorial overview: Biophysical methods: behind the scenes of the cryo-EM revolution.

Schmidt C, Robinson CV.

Curr Opin Struct Biol. 2017 Oct;46:ix-xi. doi: 10.1016/j.sbi.2017.10.018. No abstract available.

PMID:
29129309
23.

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I.

Elife. 2017 Nov 7;6. pii: e30395. doi: 10.7554/eLife.30395.

24.

Architecture of eukaryotic mRNA 3'-end processing machinery.

Casañal A, Kumar A, Hill CH, Easter AD, Emsley P, Degliesposti G, Gordiyenko Y, Santhanam B, Wolf J, Wiederhold K, Dornan GL, Skehel M, Robinson CV, Passmore LA.

Science. 2017 Nov 24;358(6366):1056-1059. doi: 10.1126/science.aao6535. Epub 2017 Oct 26.

25.

Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions.

Schmitzberger F, Richter MM, Gordiyenko Y, Robinson CV, Dadlez M, Westermann S.

EMBO J. 2017 Dec 1;36(23):3458-3482. doi: 10.15252/embj.201796636. Epub 2017 Oct 18.

26.

Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.

Manzi L, Barrow AS, Hopper JTS, Kaminska R, Kleanthous C, Robinson CV, Moses JE, Oldham NJ.

Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14873-14877. doi: 10.1002/anie.201708254. Epub 2017 Oct 20.

PMID:
28960650
27.

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.

Ambrose S, Housden NG, Gupta K, Fan J, White P, Yen HY, Marcoux J, Kleanthous C, Hopper JTS, Robinson CV.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14463-14468. doi: 10.1002/anie.201704849. Epub 2017 Sep 18.

28.

A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis.

Rouse SL, Hawthorne WJ, Berry JL, Chorev DS, Ionescu SA, Lambert S, Stylianou F, Ewert W, Mackie U, Morgan RML, Otzen D, Herbst FA, Nielsen PH, Dueholm M, Bayley H, Robinson CV, Hare S, Matthews S.

Nat Commun. 2017 Aug 15;8(1):263. doi: 10.1038/s41467-017-00361-6.

29.

Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.

Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV.

Sci Adv. 2017 Jun 16;3(6):e1701016. doi: 10.1126/sciadv.1701016. eCollection 2017 Jun.

30.

Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.

Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV.

Anal Chem. 2017 Jul 18;89(14):7425-7430. doi: 10.1021/acs.analchem.7b00922. Epub 2017 Jul 3.

31.

Efficient protein production inspired by how spiders make silk.

Kronqvist N, Sarr M, Lindqvist A, Nordling K, Otikovs M, Venturi L, Pioselli B, Purhonen P, Landreh M, Biverstål H, Toleikis Z, Sjöberg L, Robinson CV, Pelizzi N, Jörnvall H, Hebert H, Jaudzems K, Curstedt T, Rising A, Johansson J.

Nat Commun. 2017 May 23;8:15504. doi: 10.1038/ncomms15504.

32.

The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.

Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB, Crispin M, Doores KJ, Woods RJ, Benesch JLP, Robinson CV, Struwe WB.

Structure. 2017 May 2;25(5):773-782.e5. doi: 10.1016/j.str.2017.03.015. Epub 2017 Apr 20.

33.

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

Raimondi S, Porcari R, Mangione PP, Verona G, Marcoux J, Giorgetti S, Taylor GW, Ellmerich S, Ballico M, Zanini S, Pardon E, Al-Shawi R, Simons JP, Corazza A, Fogolari F, Leri M, Stefani M, Bucciantini M, Gillmore JD, Hawkins PN, Valli M, Stoppini M, Robinson CV, Steyaert J, Esposito G, Bellotti V.

Sci Rep. 2017 Apr 21;7:46711. doi: 10.1038/srep46711.

34.

Key features of an Hsp70 chaperone allosteric landscape revealed by ion-mobility native mass spectrometry and double electron-electron resonance.

Lai AL, Clerico EM, Blackburn ME, Patel NA, Robinson CV, Borbat PP, Freed JH, Gierasch LM.

J Biol Chem. 2017 May 26;292(21):8773-8785. doi: 10.1074/jbc.M116.770404. Epub 2017 Apr 20.

35.

Acetylation and phosphorylation control both local and global stability of the chloroplast F1 ATP synthase.

Schmidt C, Beilsten-Edmands V, Mohammed S, Robinson CV.

Sci Rep. 2017 Mar 9;7:44068. doi: 10.1038/srep44068.

36.

From molecular chaperones to membrane motors: through the lens of a mass spectrometrist.

Robinson CV.

Biochem Soc Trans. 2017 Feb 8;45(1):251-260. doi: 10.1042/BST20160395.

37.

Mass spectrometry captures structural intermediates in protein fiber self-assembly.

Landreh M, Andersson M, Marklund EG, Jia Q, Meng Q, Johansson J, Robinson CV, Rising A.

Chem Commun (Camb). 2017 Mar 16;53(23):3319-3322. doi: 10.1039/c7cc00307b.

38.

Structural basis for nutrient acquisition by dominant members of the human gut microbiota.

Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B.

Nature. 2017 Jan 19;541(7637):407-411. doi: 10.1038/nature20828. Epub 2017 Jan 11.

39.

The role of interfacial lipids in stabilizing membrane protein oligomers.

Gupta K, Donlan JAC, Hopper JTS, Uzdavinys P, Landreh M, Struwe WB, Drew D, Baldwin AJ, Stansfeld PJ, Robinson CV.

Nature. 2017 Jan 19;541(7637):421-424. doi: 10.1038/nature20820. Epub 2017 Jan 11.

40.

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters.

Landreh M, Marklund EG, Uzdavinys P, Degiacomi MT, Coincon M, Gault J, Gupta K, Liko I, Benesch JL, Drew D, Robinson CV.

Nat Commun. 2017 Jan 10;8:13993. doi: 10.1038/ncomms13993.

41.

Biomimetic spinning of artificial spider silk from a chimeric minispidroin.

Andersson M, Jia Q, Abella A, Lee XY, Landreh M, Purhonen P, Hebert H, Tenje M, Robinson CV, Meng Q, Plaza GR, Johansson J, Rising A.

Nat Chem Biol. 2017 Mar;13(3):262-264. doi: 10.1038/nchembio.2269. Epub 2017 Jan 9.

PMID:
28068309
42.

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex.

Kyrieleis OJP, McIntosh PB, Webb SR, Calder LJ, Lloyd J, Patel NA, Martin SR, Robinson CV, Rosenthal PB, Smerdon SJ.

Cell Rep. 2016 Dec 20;17(12):3099-3106. doi: 10.1016/j.celrep.2016.11.063.

43.

Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus.

Dietsche T, Tesfazgi Mebrhatu M, Brunner MJ, Abrusci P, Yan J, Franz-Wachtel M, Schärfe C, Zilkenat S, Grin I, Galán JE, Kohlbacher O, Lea S, Macek B, Marlovits TC, Robinson CV, Wagner S.

PLoS Pathog. 2016 Dec 15;12(12):e1006071. doi: 10.1371/journal.ppat.1006071. eCollection 2016 Dec.

44.

The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.

Ahn M, Hagan CL, Bernardo-Gancedo A, De Genst E, Newby FN, Christodoulou J, Dhulesia A, Dumoulin M, Robinson CV, Dobson CM, Kumita JR.

Biophys J. 2016 Dec 6;111(11):2358-2367. doi: 10.1016/j.bpj.2016.10.028.

45.

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

Mehmood S, Marcoux J, Gault J, Quigley A, Michaelis S, Young SG, Carpenter EP, Robinson CV.

Nat Chem. 2016 Dec;8(12):1152-1158. doi: 10.1038/nchem.2591. Epub 2016 Aug 15.

46.

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase.

Mazhab-Jafari MT, Rohou A, Schmidt C, Bueler SA, Benlekbir S, Robinson CV, Rubinstein JL.

Nature. 2016 Nov 3;539(7627):118-122. doi: 10.1038/nature19828. Epub 2016 Oct 24.

PMID:
27776355
47.

Interfacing Membrane Mimetics with Mass Spectrometry.

Marty MT, Hoi KK, Robinson CV.

Acc Chem Res. 2016 Nov 15;49(11):2459-2467. Epub 2016 Oct 13.

48.

Mass spectrometry guided structural biology.

Liko I, Allison TM, Hopper JT, Robinson CV.

Curr Opin Struct Biol. 2016 Oct;40:136-144. doi: 10.1016/j.sbi.2016.09.008. Epub 2016 Oct 7. Review.

49.

The structural basis for CD36 binding by the malaria parasite.

Hsieh FL, Turner L, Bolla JR, Robinson CV, Lavstsen T, Higgins MK.

Nat Commun. 2016 Sep 26;7:12837. doi: 10.1038/ncomms12837.

50.

Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.

Mehmood S, Corradi V, Choudhury HG, Hussain R, Becker P, Axford D, Zirah S, Rebuffat S, Tieleman DP, Robinson CV, Beis K.

J Biol Chem. 2016 Oct 7;291(41):21656-21668. Epub 2016 Aug 23.

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