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Items: 1 to 50 of 433

1.

Lipid binding attenuates channel closure of the outer membrane protein OmpF.

Liko I, Degiacomi MT, Lee S, Newport TD, Gault J, Reading E, Hopper JTS, Housden NG, White P, Colledge M, Sula A, Wallace BA, Kleanthous C, Stansfeld PJ, Bayley H, Benesch JLP, Allison TM, Robinson CV.

Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 201721152. doi: 10.1073/pnas.1721152115. [Epub ahead of print]

2.

Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters.

Romano M, Fusco G, Choudhury HG, Mehmood S, Robinson CV, Zirah S, Hegemann JD, Lescop E, Marahiel MA, Rebuffat S, De Simone A, Beis K.

ACS Chem Biol. 2018 Jun 15;13(6):1598-1609. doi: 10.1021/acschembio.8b00226. Epub 2018 May 18.

PMID:
29757605
3.

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M.

Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x.

4.

Identifying key membrane protein lipid interactions using mass spectrometry.

Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV.

Nat Protoc. 2018 May;13(5):1106-1120. doi: 10.1038/nprot.2018.014. Epub 2018 Apr 26.

PMID:
29700483
5.

The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins.

Eaton JRO, Alenazi Y, Singh K, Davies G, Geis-Asteggiante L, Kessler B, Robinson CV, Kawamura A, Bhattacharya S.

J Biol Chem. 2018 Apr 20;293(16):6134-6146. doi: 10.1074/jbc.RA117.000487. Epub 2018 Feb 27.

6.

Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ.

Bolla JR, Sauer JB, Wu D, Mehmood S, Allison TM, Robinson CV.

Nat Chem. 2018 Mar;10(3):363-371. doi: 10.1038/nchem.2919. Epub 2018 Jan 8.

7.

Precursor-Receptor Interactions in the Twin Arginine Protein Transport Pathway Probed with a New Receptor Complex Preparation.

Wojnowska M, Gault J, Yong SC, Robinson CV, Berks BC.

Biochemistry. 2018 Mar 13;57(10):1663-1671. doi: 10.1021/acs.biochem.8b00026. Epub 2018 Feb 26.

8.

Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins.

Natan E, Endoh T, Haim-Vilmovsky L, Flock T, Chalancon G, Hopper JTS, Kintses B, Horvath P, Daruka L, Fekete G, Pál C, Papp B, Oszi E, Magyar Z, Marsh JA, Elcock AH, Babu MM, Robinson CV, Sugimoto N, Teichmann SA.

Nat Struct Mol Biol. 2018 Mar;25(3):279-288. doi: 10.1038/s41594-018-0029-5. Epub 2018 Feb 12.

PMID:
29434345
9.

The structure of serum resistance-associated protein and its implications for human African trypanosomiasis.

Zoll S, Lane-Serff H, Mehmood S, Schneider J, Robinson CV, Carrington M, Higgins MK.

Nat Microbiol. 2018 Mar;3(3):295-301. doi: 10.1038/s41564-017-0085-3. Epub 2018 Jan 22.

PMID:
29358741
10.

Editorial overview: Biophysical methods: behind the scenes of the cryo-EM revolution.

Schmidt C, Robinson CV.

Curr Opin Struct Biol. 2017 Oct;46:ix-xi. doi: 10.1016/j.sbi.2017.10.018. No abstract available.

PMID:
29129309
11.

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I.

Elife. 2017 Nov 7;6. pii: e30395. doi: 10.7554/eLife.30395.

12.

Architecture of eukaryotic mRNA 3'-end processing machinery.

Casañal A, Kumar A, Hill CH, Easter AD, Emsley P, Degliesposti G, Gordiyenko Y, Santhanam B, Wolf J, Wiederhold K, Dornan GL, Skehel M, Robinson CV, Passmore LA.

Science. 2017 Nov 24;358(6366):1056-1059. doi: 10.1126/science.aao6535. Epub 2017 Oct 26.

13.

Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions.

Schmitzberger F, Richter MM, Gordiyenko Y, Robinson CV, Dadlez M, Westermann S.

EMBO J. 2017 Dec 1;36(23):3458-3482. doi: 10.15252/embj.201796636. Epub 2017 Oct 18.

14.

Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.

Manzi L, Barrow AS, Hopper JTS, Kaminska R, Kleanthous C, Robinson CV, Moses JE, Oldham NJ.

Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14873-14877. doi: 10.1002/anie.201708254. Epub 2017 Oct 20.

PMID:
28960650
15.

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.

Ambrose S, Housden NG, Gupta K, Fan J, White P, Yen HY, Marcoux J, Kleanthous C, Hopper JTS, Robinson CV.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14463-14468. doi: 10.1002/anie.201704849. Epub 2017 Sep 18.

16.

A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis.

Rouse SL, Hawthorne WJ, Berry JL, Chorev DS, Ionescu SA, Lambert S, Stylianou F, Ewert W, Mackie U, Morgan RML, Otzen D, Herbst FA, Nielsen PH, Dueholm M, Bayley H, Robinson CV, Hare S, Matthews S.

Nat Commun. 2017 Aug 15;8(1):263. doi: 10.1038/s41467-017-00361-6.

17.

Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.

Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV.

Sci Adv. 2017 Jun 16;3(6):e1701016. doi: 10.1126/sciadv.1701016. eCollection 2017 Jun.

18.

Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.

Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV.

Anal Chem. 2017 Jul 18;89(14):7425-7430. doi: 10.1021/acs.analchem.7b00922. Epub 2017 Jul 3.

19.

Efficient protein production inspired by how spiders make silk.

Kronqvist N, Sarr M, Lindqvist A, Nordling K, Otikovs M, Venturi L, Pioselli B, Purhonen P, Landreh M, Biverstål H, Toleikis Z, Sjöberg L, Robinson CV, Pelizzi N, Jörnvall H, Hebert H, Jaudzems K, Curstedt T, Rising A, Johansson J.

Nat Commun. 2017 May 23;8:15504. doi: 10.1038/ncomms15504.

20.

The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.

Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB, Crispin M, Doores KJ, Woods RJ, Benesch JLP, Robinson CV, Struwe WB.

Structure. 2017 May 2;25(5):773-782.e5. doi: 10.1016/j.str.2017.03.015. Epub 2017 Apr 20.

21.

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

Raimondi S, Porcari R, Mangione PP, Verona G, Marcoux J, Giorgetti S, Taylor GW, Ellmerich S, Ballico M, Zanini S, Pardon E, Al-Shawi R, Simons JP, Corazza A, Fogolari F, Leri M, Stefani M, Bucciantini M, Gillmore JD, Hawkins PN, Valli M, Stoppini M, Robinson CV, Steyaert J, Esposito G, Bellotti V.

Sci Rep. 2017 Apr 21;7:46711. doi: 10.1038/srep46711.

22.

Key features of an Hsp70 chaperone allosteric landscape revealed by ion-mobility native mass spectrometry and double electron-electron resonance.

Lai AL, Clerico EM, Blackburn ME, Patel NA, Robinson CV, Borbat PP, Freed JH, Gierasch LM.

J Biol Chem. 2017 May 26;292(21):8773-8785. doi: 10.1074/jbc.M116.770404. Epub 2017 Apr 20.

23.

Acetylation and phosphorylation control both local and global stability of the chloroplast F1 ATP synthase.

Schmidt C, Beilsten-Edmands V, Mohammed S, Robinson CV.

Sci Rep. 2017 Mar 9;7:44068. doi: 10.1038/srep44068.

24.

From molecular chaperones to membrane motors: through the lens of a mass spectrometrist.

Robinson CV.

Biochem Soc Trans. 2017 Feb 8;45(1):251-260. doi: 10.1042/BST20160395.

25.

Mass spectrometry captures structural intermediates in protein fiber self-assembly.

Landreh M, Andersson M, Marklund EG, Jia Q, Meng Q, Johansson J, Robinson CV, Rising A.

Chem Commun (Camb). 2017 Mar 16;53(23):3319-3322. doi: 10.1039/c7cc00307b.

26.

Structural basis for nutrient acquisition by dominant members of the human gut microbiota.

Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B.

Nature. 2017 Jan 19;541(7637):407-411. doi: 10.1038/nature20828. Epub 2017 Jan 11.

27.

The role of interfacial lipids in stabilizing membrane protein oligomers.

Gupta K, Donlan JAC, Hopper JTS, Uzdavinys P, Landreh M, Struwe WB, Drew D, Baldwin AJ, Stansfeld PJ, Robinson CV.

Nature. 2017 Jan 19;541(7637):421-424. doi: 10.1038/nature20820. Epub 2017 Jan 11.

28.

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters.

Landreh M, Marklund EG, Uzdavinys P, Degiacomi MT, Coincon M, Gault J, Gupta K, Liko I, Benesch JL, Drew D, Robinson CV.

Nat Commun. 2017 Jan 10;8:13993. doi: 10.1038/ncomms13993.

29.

Biomimetic spinning of artificial spider silk from a chimeric minispidroin.

Andersson M, Jia Q, Abella A, Lee XY, Landreh M, Purhonen P, Hebert H, Tenje M, Robinson CV, Meng Q, Plaza GR, Johansson J, Rising A.

Nat Chem Biol. 2017 Mar;13(3):262-264. doi: 10.1038/nchembio.2269. Epub 2017 Jan 9.

PMID:
28068309
30.

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex.

Kyrieleis OJP, McIntosh PB, Webb SR, Calder LJ, Lloyd J, Patel NA, Martin SR, Robinson CV, Rosenthal PB, Smerdon SJ.

Cell Rep. 2016 Dec 20;17(12):3099-3106. doi: 10.1016/j.celrep.2016.11.063.

31.

Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus.

Dietsche T, Tesfazgi Mebrhatu M, Brunner MJ, Abrusci P, Yan J, Franz-Wachtel M, Schärfe C, Zilkenat S, Grin I, Galán JE, Kohlbacher O, Lea S, Macek B, Marlovits TC, Robinson CV, Wagner S.

PLoS Pathog. 2016 Dec 15;12(12):e1006071. doi: 10.1371/journal.ppat.1006071. eCollection 2016 Dec.

32.

The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.

Ahn M, Hagan CL, Bernardo-Gancedo A, De Genst E, Newby FN, Christodoulou J, Dhulesia A, Dumoulin M, Robinson CV, Dobson CM, Kumita JR.

Biophys J. 2016 Dec 6;111(11):2358-2367. doi: 10.1016/j.bpj.2016.10.028.

33.

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

Mehmood S, Marcoux J, Gault J, Quigley A, Michaelis S, Young SG, Carpenter EP, Robinson CV.

Nat Chem. 2016 Dec;8(12):1152-1158. doi: 10.1038/nchem.2591. Epub 2016 Aug 15.

34.

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase.

Mazhab-Jafari MT, Rohou A, Schmidt C, Bueler SA, Benlekbir S, Robinson CV, Rubinstein JL.

Nature. 2016 Nov 3;539(7627):118-122. doi: 10.1038/nature19828. Epub 2016 Oct 24.

PMID:
27776355
35.

Interfacing Membrane Mimetics with Mass Spectrometry.

Marty MT, Hoi KK, Robinson CV.

Acc Chem Res. 2016 Nov 15;49(11):2459-2467. Epub 2016 Oct 13.

36.

Mass spectrometry guided structural biology.

Liko I, Allison TM, Hopper JT, Robinson CV.

Curr Opin Struct Biol. 2016 Oct;40:136-144. doi: 10.1016/j.sbi.2016.09.008. Epub 2016 Oct 7. Review.

37.

The structural basis for CD36 binding by the malaria parasite.

Hsieh FL, Turner L, Bolla JR, Robinson CV, Lavstsen T, Higgins MK.

Nat Commun. 2016 Sep 26;7:12837. doi: 10.1038/ncomms12837.

38.

Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.

Mehmood S, Corradi V, Choudhury HG, Hussain R, Becker P, Axford D, Zirah S, Rebuffat S, Tieleman DP, Robinson CV, Beis K.

J Biol Chem. 2016 Oct 7;291(41):21656-21668. Epub 2016 Aug 23.

39.

Optimal Synthetic Glycosylation of a Therapeutic Antibody.

Parsons TB, Struwe WB, Gault J, Yamamoto K, Taylor TA, Raj R, Wals K, Mohammed S, Robinson CV, Benesch JL, Davis BG.

Angew Chem Weinheim Bergstr Ger. 2016 Feb 12;128(7):2407-2413. Epub 2016 Jan 12.

40.

The interchange of immunophilins leads to parallel pathways and different intermediates in the assembly of Hsp90 glucocorticoid receptor complexes.

Ebong IO, Beilsten-Edmands V, Patel NA, Morgner N, Robinson CV.

Cell Discov. 2016 Apr 5;2:16002. doi: 10.1038/celldisc.2016.2. eCollection 2016.

41.

The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.

Rajasekar KV, Zdanowski K, Yan J, Hopper JT, Francis ML, Seepersad C, Sharp C, Pecqueur L, Werner JM, Robinson CV, Mohammed S, Potts JR, Kleanthous C.

Nat Commun. 2016 Jul 19;7:12194. doi: 10.1038/ncomms12194.

42.

Dimer interface of bovine cytochrome c oxidase is influenced by local posttranslational modifications and lipid binding.

Liko I, Degiacomi MT, Mohammed S, Yoshikawa S, Schmidt C, Robinson CV.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8230-5. doi: 10.1073/pnas.1600354113. Epub 2016 Jun 30.

43.

Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase.

Mikhailov VA, Liko I, Mize TH, Bush MF, Benesch JL, Robinson CV.

Anal Chem. 2016 Jul 19;88(14):7060-7. doi: 10.1021/acs.analchem.6b00645. Epub 2016 Jul 5.

PMID:
27328020
44.

Structural evidence for Nap1-dependent H2A-H2B deposition and nucleosome assembly.

Aguilar-Gurrieri C, Larabi A, Vinayachandran V, Patel NA, Yen K, Reja R, Ebong IO, Schoehn G, Robinson CV, Pugh BF, Panne D.

EMBO J. 2016 Jul 1;35(13):1465-82. doi: 10.15252/embj.201694105. Epub 2016 May 25.

45.

Unraveling the Composition and Behavior of Heterogeneous Lipid Nanodiscs by Mass Spectrometry.

Hoi KK, Robinson CV, Marty MT.

Anal Chem. 2016 Jun 21;88(12):6199-204. doi: 10.1021/acs.analchem.6b00851. Epub 2016 Jun 1.

46.

Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly.

Podobnik M, Savory P, Rojko N, Kisovec M, Wood N, Hambley R, Pugh J, Wallace EJ, McNeill L, Bruce M, Liko I, Allison TM, Mehmood S, Yilmaz N, Kobayashi T, Gilbert RJ, Robinson CV, Jayasinghe L, Anderluh G.

Nat Commun. 2016 May 12;7:11598. doi: 10.1038/ncomms11598.

47.

A combined computational and structural model of the full-length human prolactin receptor.

Bugge K, Papaleo E, Haxholm GW, Hopper JT, Robinson CV, Olsen JG, Lindorff-Larsen K, Kragelund BB.

Nat Commun. 2016 May 13;7:11578. doi: 10.1038/ncomms11578.

48.

A sliding selectivity scale for lipid binding to membrane proteins.

Landreh M, Marty MT, Gault J, Robinson CV.

Curr Opin Struct Biol. 2016 Aug;39:54-60. doi: 10.1016/j.sbi.2016.04.005. Epub 2016 May 4. Review.

49.

Low Charge and Reduced Mobility of Membrane Protein Complexes Has Implications for Calibration of Collision Cross Section Measurements.

Allison TM, Landreh M, Benesch JLP, Robinson CV.

Anal Chem. 2016 Jun 7;88(11):5879-5884. doi: 10.1021/acs.analchem.6b00691. Epub 2016 May 13.

50.

Negative Ions Enhance Survival of Membrane Protein Complexes.

Liko I, Hopper JT, Allison TM, Benesch JL, Robinson CV.

J Am Soc Mass Spectrom. 2016 Jun;27(6):1099-104. doi: 10.1007/s13361-016-1381-5. Epub 2016 Apr 22.

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