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2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial.

Kraus WE, Bhapkar M, Huffman KM, Pieper CF, Krupa Das S, Redman LM, Villareal DT, Rochon J, Roberts SB, Ravussin E, Holloszy JO, Fontana L; CALERIE Investigators.

Lancet Diabetes Endocrinol. 2019 Jul 11. pii: S2213-8587(19)30151-2. doi: 10.1016/S2213-8587(19)30151-2. [Epub ahead of print]


Different and Unequal: A Qualitative Evaluation of Salient Factors Influencing Energy Intake in Adults with Overweight and Obesity.

Dao MC, Messer E, Conigliaro T, Sakaida K, Ouellette AF, Himaras V, Thiron S, Roberts SB.

Nutrients. 2019 Jun 18;11(6). pii: E1365. doi: 10.3390/nu11061365.


Development of a Videoconference-Adapted Version of the Community Diabetes Prevention Program, and Comparison of Weight Loss With In-Person Program Delivery.

Taetzsch A, Gilhooly CH, Bukhari A, Das SK, Martin E, Hatch AM, Silver RE, Montain SJ, Roberts SB.

Mil Med. 2019 Apr 24. pii: usz069. doi: 10.1093/milmed/usz069. [Epub ahead of print]


Fast-Food Offerings in the United States in 1986, 1991, and 2016 Show Large Increases in Food Variety, Portion Size, Dietary Energy, and Selected Micronutrients.

McCrory MA, Harbaugh AG, Appeadu S, Roberts SB.

J Acad Nutr Diet. 2019 Jun;119(6):923-933. doi: 10.1016/j.jand.2018.12.004. Epub 2019 Feb 27.


Pacific geoduck (Panopea generosa) resilience to natural pH variation.

Spencer LH, Horwith M, Lowe AT, Venkataraman YR, Timmins-Schiffman E, Nunn BL, Roberts SB.

Comp Biochem Physiol Part D Genomics Proteomics. 2019 Jun;30:91-101. doi: 10.1016/j.cbd.2019.01.010. Epub 2019 Jan 24.


Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors.

Yeung KS, Beno BR, Mosure K, Zhu J, Grant-Young KA, Parcella K, Anjanappa P, Bora RO, Selvakumar K, Wang YK, Fang H, Krause R, Rigat K, Liu M, Lemm J, Sheriff S, Witmer M, Tredup J, Jardel A, Kish K, Parker D, Haskell R, Santone K, Meanwell NA, Soars MG, Roberts SB, Kadow JF.

ACS Med Chem Lett. 2018 Nov 5;9(12):1217-1222. doi: 10.1021/acsmedchemlett.8b00379. eCollection 2018 Dec 13.


Coral epigenetic responses to nutrient stress: Histone H2A.X phosphorylation dynamics and DNA methylation in the staghorn coral Acropora cervicornis.

Rodriguez-Casariego JA, Ladd MC, Shantz AA, Lopes C, Cheema MS, Kim B, Roberts SB, Fourqurean JW, Ausio J, Burkepile DE, Eirin-Lopez JM.

Ecol Evol. 2018 Nov 23;8(23):12193-12207. doi: 10.1002/ece3.4678. eCollection 2018 Dec.


Exogenous steroid-induced hypoadrenalism in a person living with HIV caused by a drug-drug interaction between cobicistat and intrabursal triamcinolone.

Makaram N, Russell CD, Roberts SB, Stevens J, Macpherson G.

BMJ Case Rep. 2018 Dec 14;11(1). pii: e226912. doi: 10.1136/bcr-2018-226912.


Measured energy content of frequently purchased restaurant meals: multi-country cross sectional study.

Roberts SB, Das SK, Suen VMM, Pihlajamäki J, Kuriyan R, Steiner-Asiedu M, Taetzsch A, Anderson AK, Silver RE, Barger K, Krauss A, Karhunen L, Zhang X, Hambly C, Schwab U, Triffoni-Melo AT, Taylor SF, Economos C, Kurpad AV, Speakman JR.

BMJ. 2018 Dec 12;363:k4864. doi: 10.1136/bmj.k4864.


Are Gluten-Free Diets More Nutritious? An Evaluation of Self-Selected and Recommended Gluten-Free and Gluten-Containing Dietary Patterns.

Taetzsch A, Das SK, Brown C, Krauss A, Silver RE, Roberts SB.

Nutrients. 2018 Dec 3;10(12). pii: E1881. doi: 10.3390/nu10121881. Review.


Making progress on the global crisis of obesity and weight management.

Lean MEJ, Astrup A, Roberts SB.

BMJ. 2018 Jun 13;361:k2538. doi: 10.1136/bmj.k2538. No abstract available.


Effectiveness of an Energy Management Training Course on Employee Well-Being: A Randomized Controlled Trial.

Das SK, Mason ST, Vail TA, Rogers GV, Livingston KA, Whelan JG, Chin MK, Blanchard CM, Turgiss JL, Roberts SB.

Am J Health Promot. 2019 Jan;33(1):118-130. doi: 10.1177/0890117118776875. Epub 2018 May 28.


Consistent differences in fitness traits across multiple generations of Olympia oysters.

Silliman KE, Bowyer TK, Roberts SB.

Sci Rep. 2018 Apr 17;8(1):6080. doi: 10.1038/s41598-018-24455-3.


A Pilot Randomized Controlled Trial of a New Supplementary Food Designed to Enhance Cognitive Performance during Prevention and Treatment of Malnutrition in Childhood.

Roberts SB, Franceschini MA, Krauss A, Lin PY, de Sa AB, Có R, Taylor S, Brown C, Chen O, Johnson EJ, Pruzensky W, Schlossman N, Balé C, Wu KT, Hagan K, Saltzman E, Muentener P.

Curr Dev Nutr. 2017 Nov;1(11). pii: e000885. doi: 10.3945/cdn.117.000885. Epub 2017 Oct 12.


Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures: Behavioral Domain.

Lytle LA, Nicastro HL, Roberts SB, Evans M, Jakicic JM, Laposky AD, Loria CM.

Obesity (Silver Spring). 2018 Apr;26 Suppl 2:S16-S24. doi: 10.1002/oby.22157.


Curcumin and piperine supplementation of obese mice under caloric restriction modulates body fat and interleukin-1β.

Miyazawa T, Nakagawa K, Kim SH, Thomas MJ, Paul L, Zingg JM, Dolnikowski GG, Roberts SB, Kimura F, Miyazawa T, Azzi A, Meydani M.

Nutr Metab (Lond). 2018 Feb 6;15:12. doi: 10.1186/s12986-018-0250-6. eCollection 2018.


Differential response to stress in Ostrea lurida as measured by gene expression.

Heare JE, White SJ, Vadopalas B, Roberts SB.

PeerJ. 2018 Jan 15;6:e4261. doi: 10.7717/peerj.4261. eCollection 2018.


Epigenetic considerations in aquaculture.

Gavery MR, Roberts SB.

PeerJ. 2017 Dec 7;5:e4147. doi: 10.7717/peerj.4147. eCollection 2017.


Effects of Two Years of Calorie Restriction on Aerobic Capacity and Muscle Strength.

Racette SB, Rochon J, Uhrich ML, Villareal DT, DAS SK, Fontana L, Bhapkar M, Martin CK, Redman LM, Fuss PJ, Roberts SB, Kraus WE.

Med Sci Sports Exerc. 2017 Nov;49(11):2240-2249. doi: 10.1249/MSS.0000000000001353.


A systematic review of the effects of platelet rich plasma on outcomes for patients with knee osteoarthritis and following total knee arthroplasty.

Muchedzi TA, Roberts SB.

Surgeon. 2018 Aug;16(4):250-258. doi: 10.1016/j.surge.2017.08.004. Epub 2017 Sep 22. Review.


Genotoype-by-sequencing of three geographically distinct populations of Olympia oysters, Ostrea lurida.

White SJ, Vadopalas B, Silliman K, Roberts SB.

Sci Data. 2017 Sep 12;4:170130. doi: 10.1038/sdata.2017.130.


Reply to S-S Zhou and Y Zhou.

Karl JP, Meydani SN, Roberts SB.

Am J Clin Nutr. 2017 Sep;106(3):947-948. doi: 10.3945/ajcn.117.160192. No abstract available.


Fecal concentrations of bacterially derived vitamin K forms are associated with gut microbiota composition but not plasma or fecal cytokine concentrations in healthy adults.

Karl JP, Meydani M, Barnett JB, Vanegas SM, Barger K, Fu X, Goldin B, Kane A, Rasmussen H, Vangay P, Knights D, Jonnalagadda SS, Saltzman E, Roberts SB, Meydani SN, Booth SL.

Am J Clin Nutr. 2017 Oct;106(4):1052-1061. doi: 10.3945/ajcn.117.155424. Epub 2017 Aug 16.


Genetic and epigenetic insight into morphospecies in a reef coral.

Dimond JL, Gamblewood SK, Roberts SB.

Mol Ecol. 2017 Oct;26(19):5031-5042. doi: 10.1111/mec.14252. Epub 2017 Aug 12.


Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor.

Parcella K, Eastman K, Yeung KS, Grant-Young KA, Zhu J, Wang T, Zhang Z, Yin Z, Parker D, Mosure K, Fang H, Wang YK, Lemm J, Zhuo X, Hanumegowda U, Liu M, Rigat K, Donoso M, Tuttle M, Zvyaga T, Haarhoff Z, Meanwell NA, Soars MG, Roberts SB, Kadow JF.

ACS Med Chem Lett. 2017 Jun 29;8(7):771-774. doi: 10.1021/acsmedchemlett.7b00211. eCollection 2017 Jul 13.


Integrating Discovery-driven Proteomics and Selected Reaction Monitoring To Develop a Noninvasive Assay for Geoduck Reproductive Maturation.

Timmins-Schiffman EB, Crandall GA, Vadopalas B, Riffle ME, Nunn BL, Roberts SB.

J Proteome Res. 2017 Sep 1;16(9):3298-3309. doi: 10.1021/acs.jproteome.7b00288. Epub 2017 Aug 11.


Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.

Zheng BZ, D'Andrea SV, Hanumegowda U, Knipe JO, Mosure K, Zhuo X, Lemm JA, Liu M, Rigat KL, Wang YK, Fang H, Poronsky C, Cutrone J, Wu DR, Arunachalam PN, Balapragalathan TJ, Arumugam A, Mathur A, Meanwell NA, Gao M, Roberts SB, Kadow JF.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3294-3300. doi: 10.1016/j.bmcl.2017.06.024. Epub 2017 Jun 11.


The Messy Truth about Weight Loss.

Roberts SB, Das SK.

Sci Am. 2017 May 16;316(6):36-41. doi: 10.1038/scientificamerican0617-36. No abstract available.


Weight loss in videoconference and in-person iDiet weight loss programs in worksites and community groups.

Das SK, Brown C, Urban LE, O'Toole J, Gamache MMG, Weerasekara YK, Roberts SB.

Obesity (Silver Spring). 2017 Jun;25(6):1033-1041. doi: 10.1002/oby.21854. Epub 2017 Apr 28.


Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.

Yeung KS, Beno BR, Parcella K, Bender JA, Grant-Young KA, Nickel A, Gunaga P, Anjanappa P, Bora RO, Selvakumar K, Rigat K, Wang YK, Liu M, Lemm J, Mosure K, Sheriff S, Wan C, Witmer M, Kish K, Hanumegowda U, Zhuo X, Shu YZ, Parker D, Haskell R, Ng A, Gao Q, Colston E, Raybon J, Grasela DM, Santone K, Gao M, Meanwell NA, Sinz M, Soars MG, Knipe JO, Roberts SB, Kadow JF.

J Med Chem. 2017 May 25;60(10):4369-4385. doi: 10.1021/acs.jmedchem.7b00328. Epub 2017 May 4.


Association of nutrition club membership with markers of health: a cross sectional study.

Das SK, Vail TA, Lebrón-Torres N, Livingston KA, Roberts SB, Rogers GT, Gilhooly CH, Urban LE, Saltzman E, McKeown NM, Folta SC.

BMC Public Health. 2017 Apr 11;17(1):310. doi: 10.1186/s12889-017-4219-6.


A Randomized Controlled Trial of Two Ready-to-Use Supplementary Foods Demonstrates Benefit of the Higher Dairy Supplement for Reduced Wasting in Mothers, and Differential Impact in Infants and Children Associated With Maternal Supplement Response.

Schlossman N, Brown C, Batra P, de Sa AB, Balan I, Balan A, Gamache MG, Wood L, Pruzensky W, Saltzman E, Roberts SB, Balé C.

Food Nutr Bull. 2017 Sep;38(3):275-290. doi: 10.1177/0379572117700754. Epub 2017 Apr 4.


A pilot and feasibility study to assess children's consumption in quick-service restaurants using plate waste methodology.

Cohen JF, Roberts SB, Anzman-Frasca S, Gamache MM, Lynskey VM, Matthews E, Mueller MP, Sharma S, Economos CD.

BMC Public Health. 2017 Mar 15;17(1):259. doi: 10.1186/s12889-017-4171-5.


Body-composition changes in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)-2 study: a 2-y randomized controlled trial of calorie restriction in nonobese humans.

Das SK, Roberts SB, Bhapkar MV, Villareal DT, Fontana L, Martin CK, Racette SB, Fuss PJ, Kraus WE, Wong WW, Saltzman E, Pieper CF, Fielding RA, Schwartz AV, Ravussin E, Redman LM; CALERIE-2 Study Group.

Am J Clin Nutr. 2017 Apr;105(4):913-927. doi: 10.3945/ajcn.116.137232. Epub 2017 Feb 22.


Dietary Fiber and the Human Gut Microbiota: Application of Evidence Mapping Methodology.

Sawicki CM, Livingston KA, Obin M, Roberts SB, Chung M, McKeown NM.

Nutrients. 2017 Feb 10;9(2). pii: E125. doi: 10.3390/nu9020125.


Substituting whole grains for refined grains in a 6-wk randomized trial favorably affects energy-balance metrics in healthy men and postmenopausal women.

Karl JP, Meydani M, Barnett JB, Vanegas SM, Goldin B, Kane A, Rasmussen H, Saltzman E, Vangay P, Knights D, Chen CO, Das SK, Jonnalagadda SS, Meydani SN, Roberts SB.

Am J Clin Nutr. 2017 Mar;105(3):589-599. doi: 10.3945/ajcn.116.139683. Epub 2017 Feb 8. Erratum in: Am J Clin Nutr. 2017 Aug;106(2):708.


The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase.

Eastman KJ, Parcella K, Yeung KS, Grant-Young KA, Zhu J, Wang T, Zhang Z, Yin Z, Beno BR, Sheriff S, Kish K, Tredup J, Jardel AG, Halan V, Ghosh K, Parker D, Mosure K, Fang H, Wang YK, Lemm J, Zhuo X, Hanumegowda U, Rigat K, Donoso M, Tuttle M, Zvyaga T, Haarhoff Z, Meanwell NA, Soars MG, Roberts SB, Kadow JF.

Medchemcomm. 2017 Feb 8;8(4):796-806. doi: 10.1039/c6md00636a. eCollection 2017 Apr 1.


Nutrition Status of Primary School Students in Two Rural Regions of Guinea-Bissau.

Saltzman E, Schlossman N, Brown CA, Balan I, Fuss P, Batra P, Braima de Sa A, Shea MK, Pruzensky WM, Bale C, Roberts SB.

Food Nutr Bull. 2017 Mar;38(1):103-114. doi: 10.1177/0379572116679071. Epub 2016 Dec 27.


Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase.

Parcella K, Nickel A, Beno BR, Sheriff S, Wan C, Wang YK, Roberts SB, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):295-298. doi: 10.1016/j.bmcl.2016.11.054. Epub 2016 Nov 22.


Inversion of Correia Repeat Enclosed Elements in Neisseria gonorrhoeae.

Elbeyioglu F, Roberts SB, Spencer-Smith R, Pulijala M, Zelewska MA, Nebel JC, Snyder LA.

Microbiology. 2016 Nov 16. doi: 10.1099/mic.0.000394. [Epub ahead of print]


Healthy Behaviors Potentially Due to Calorie Restriction-Reply.

Martin CK, Bhapkar M, Roberts SB; CALERIE Study Group.

JAMA Intern Med. 2016 Nov 1;176(11):1724. doi: 10.1001/jamainternmed.2016.6201. No abstract available.


Correia Repeat Enclosed Elements and Non-Coding RNAs in the Neisseria Species.

Roberts SB, Spencer-Smith R, Shah M, Nebel JC, Cook RT, Snyder LA.

Microorganisms. 2016 Aug 25;4(3). pii: E31. doi: 10.3390/microorganisms4030031.


Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans.

Meydani SN, Das SK, Pieper CF, Lewis MR, Klein S, Dixit VD, Gupta AK, Villareal DT, Bhapkar M, Huang M, Fuss PJ, Roberts SB, Holloszy JO, Fontana L.

Aging (Albany NY). 2016 Jul;8(7):1416-31. doi: 10.18632/aging.100994.


Development of a Publicly Available, Comprehensive Database of Fiber and Health Outcomes: Rationale and Methods.

Livingston KA, Chung M, Sawicki CM, Lyle BJ, Wang DD, Roberts SB, McKeown NM.

PLoS One. 2016 Jun 27;11(6):e0156961. doi: 10.1371/journal.pone.0156961. eCollection 2016.


Effect of Calorie Restriction on Mood, Quality of Life, Sleep, and Sexual Function in Healthy Nonobese Adults: The CALERIE 2 Randomized Clinical Trial.

Martin CK, Bhapkar M, Pittas AG, Pieper CF, Das SK, Williamson DA, Scott T, Redman LM, Stein R, Gilhooly CH, Stewart T, Robinson L, Roberts SB; Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) Phase 2 Study Group.

JAMA Intern Med. 2016 Jun 1;176(6):743-52. doi: 10.1001/jamainternmed.2016.1189.


Effectiveness of Workplace Weight Management Interventions: a Systematic Review.

Weerasekara YK, Roberts SB, Kahn MA, LaVertu AE, Hoffman B, Das SK.

Curr Obes Rep. 2016 Jun;5(2):298-306. doi: 10.1007/s13679-016-0205-z. Review.


Factors influencing the evaluation and management of neuromuscular scoliosis: A review of the literature.

Roberts SB, Tsirikos AI.

J Back Musculoskelet Rehabil. 2016 Nov 21;29(4):613-623. Review.


Thoracolumbar kyphosis in patients with mucopolysaccharidoses: clinical outcomes and predictive radiographic factors for progression of deformity.

Roberts SB, Dryden R, Tsirikos AI.

Bone Joint J. 2016 Feb;98-B(2):229-37. doi: 10.1302/0301-620X.98B2.36144.


Energy Contents of Frequently Ordered Restaurant Meals and Comparison with Human Energy Requirements and U.S. Department of Agriculture Database Information: A Multisite Randomized Study.

Urban LE, Weber JL, Heyman MB, Schichtl RL, Verstraete S, Lowery NS, Das SK, Schleicher MM, Rogers G, Economos C, Masters WA, Roberts SB.

J Acad Nutr Diet. 2016 Apr;116(4):590-8.e6. doi: 10.1016/j.jand.2015.11.009. Epub 2016 Jan 20.


Discovery and preclinical evaluation of potent, orally bioavailable, metabolically stable cyclopropylindolobenzazepine acylsulfonamides as thumb site 1 inhibitors of the hepatitis c virus NS5B RNA-dependent, RNA polymerase.

Hewawasam P, Tu Y, Gao M, Hanumegowda U, Knipe J, Lemm JA, Parker DD, Rigat KL, Roberts SB, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):936-940. doi: 10.1016/j.bmcl.2015.12.058. Epub 2015 Dec 19.


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