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Items: 1 to 50 of 66

1.

Recombinant Porcine Reproductive and Respiratory Syndrome Virus Expressing Membrane-Bound Interleukin-15 as an Immunomodulatory Adjuvant Enhances NK and γδ T Cell Responses and Confers Heterologous Protection.

Cao QM, Ni YY, Cao D, Tian D, Yugo DM, Heffron CL, Overend C, Subramaniam S, Rogers AJ, Catanzaro N, LeRoith T, Roberts PC, Meng XJ.

J Virol. 2018 Jun 13;92(13). pii: e00007-18. doi: 10.1128/JVI.00007-18. Print 2018 Jul 1.

PMID:
29643245
2.

A Universal Influenza Vaccine: The Strategic Plan for the National Institute of Allergy and Infectious Diseases.

Erbelding EJ, Post DJ, Stemmy EJ, Roberts PC, Augustine AD, Ferguson S, Paules CI, Graham BS, Fauci AS.

J Infect Dis. 2018 Jul 2;218(3):347-354. doi: 10.1093/infdis/jiy103.

PMID:
29506129
3.

Alternating electric fields (TTFields) in combination with paclitaxel are therapeutically effective against ovarian cancer cells in vitro and in vivo.

Voloshin T, Munster M, Blatt R, Shteingauz A, Roberts PC, Schmelz EM, Giladi M, Schneiderman RS, Zeevi E, Porat Y, Bomzon Z, Urman N, Itzhaki A, Cahal S, Kirson ED, Weinberg U, Palti Y.

Int J Cancer. 2016 Dec 15;139(12):2850-2858. doi: 10.1002/ijc.30406. Epub 2016 Sep 19.

4.

Interleukin-12 Immunomodulation Delays the Onset of Lethal Peritoneal Disease of Ovarian Cancer.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

J Interferon Cytokine Res. 2016 Jan;36(1):62-73. doi: 10.1089/jir.2015.0049. Epub 2015 Oct 2.

5.

Ovarian tumor-initiating cells display a flexible metabolism.

Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM.

Exp Cell Res. 2014 Oct 15;328(1):44-57. doi: 10.1016/j.yexcr.2014.08.028. Epub 2014 Aug 27.

6.

Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines.

Khan T, Heffron CL, High KP, Roberts PC.

Virol J. 2014 May 3;11:78. doi: 10.1186/1743-422X-11-78.

7.

Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model.

Babahosseini H, Ketene AN, Schmelz EM, Roberts PC, Agah M.

Nanomedicine. 2014 Jul;10(5):1013-9. doi: 10.1016/j.nano.2013.12.009. Epub 2014 Jan 6.

8.

Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells.

Salmanzadeh A, Sano MB, Gallo-Villanueva RC, Roberts PC, Schmelz EM, Davalos RV.

Biomicrofluidics. 2013 Jan 23;7(1):11809. doi: 10.1063/1.4788921. eCollection 2013.

9.

Tailored vaccines targeting the elderly using whole inactivated influenza vaccines bearing cytokine immunomodulators.

Khan T, Heffron CL, High KP, Roberts PC.

J Interferon Cytokine Res. 2014 Feb;34(2):129-39. doi: 10.1089/jir.2012.0119. Epub 2013 Oct 8.

10.

Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Integr Biol (Camb). 2013 Nov;5(11):1385-92. doi: 10.1039/c3ib40121a. Epub 2013 Sep 20.

11.

The parity-associated microenvironmental niche in the omental fat band is refractory to ovarian cancer metastasis.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

Cancer Prev Res (Phila). 2013 Nov;6(11):1182-93. doi: 10.1158/1940-6207.CAPR-13-0227. Epub 2013 Sep 10.

12.

In vitro model of spontaneous mouse OSE transformation.

Roberts PC, Schmelz EM.

Methods Mol Biol. 2013;1049:393-408. doi: 10.1007/978-1-62703-547-7_30.

PMID:
23913233
13.

Intra-abdominal fat depots represent distinct immunomodulatory microenvironments: a murine model.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

PLoS One. 2013 Jun 12;8(6):e66477. doi: 10.1371/journal.pone.0066477. Print 2013.

14.

Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model.

Salmanzadeh A, Elvington ES, Roberts PC, Schmelz EM, Davalos RV.

Integr Biol (Camb). 2013 Jun;5(6):843-52. doi: 10.1039/c3ib00008g.

15.

Metabolic changes during ovarian cancer progression as targets for sphingosine treatment.

Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM.

Exp Cell Res. 2013 Jun 10;319(10):1431-42. doi: 10.1016/j.yexcr.2013.02.017. Epub 2013 Mar 19.

16.

Roles of bioactive sphingolipid metabolites in ovarian cancer cell biomechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:2436-9. doi: 10.1109/EMBC.2012.6346456.

PMID:
23366417
17.

Regulation of cytoskeleton organization by sphingosine in a mouse cell model of progressive ovarian cancer.

Creekmore AL, Heffron CL, Brayfield BP, Roberts PC, Schmelz EM.

Biomolecules. 2013 Jul 16;3(3):386-407. doi: 10.3390/biom3030386.

18.

Dietary abscisic acid ameliorates influenza-virus-associated disease and pulmonary immunopathology through a PPARγ-dependent mechanism.

Hontecillas R, Roberts PC, Carbo A, Vives C, Horne WT, Genis S, Velayudhan B, Bassaganya-Riera J.

J Nutr Biochem. 2013 Jun;24(6):1019-27. doi: 10.1016/j.jnutbio.2012.07.010. Epub 2012 Sep 17.

19.

Actin filaments play a primary role for structural integrity and viscoelastic response in cells.

Ketene AN, Roberts PC, Shea AA, Schmelz EM, Agah M.

Integr Biol (Camb). 2012 May;4(5):540-9. doi: 10.1039/c2ib00168c. Epub 2012 Mar 26.

PMID:
22446682
20.

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer.

Wang K, Kan J, Yuen ST, Shi ST, Chu KM, Law S, Chan TL, Kan Z, Chan AS, Tsui WY, Lee SP, Ho SL, Chan AK, Cheng GH, Roberts PC, Rejto PA, Gibson NW, Pocalyko DJ, Mao M, Xu J, Leung SY.

Nat Genet. 2011 Oct 30;43(12):1219-23. doi: 10.1038/ng.982.

PMID:
22037554
21.

MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays.

Nikkhah M, Strobl JS, Schmelz EM, Roberts PC, Zhou H, Agah M.

Biomaterials. 2011 Oct;32(30):7625-32. doi: 10.1016/j.biomaterials.2011.06.041. Epub 2011 Jul 18.

PMID:
21764441
22.

The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures.

Ketene AN, Schmelz EM, Roberts PC, Agah M.

Nanomedicine. 2012 Jan;8(1):93-102. doi: 10.1016/j.nano.2011.05.012. Epub 2011 Jun 23. Erratum in: Nanomedicine. 2012 Apr;8(3):391.

PMID:
21704191
23.

Changes in gene expression and cellular architecture in an ovarian cancer progression model.

Creekmore AL, Silkworth WT, Cimini D, Jensen RV, Roberts PC, Schmelz EM.

PLoS One. 2011 Mar 3;6(3):e17676. doi: 10.1371/journal.pone.0017676.

24.

PPAR-gamma activation as an anti-inflammatory therapy for respiratory virus infections.

Bassaganya-Riera J, Song R, Roberts PC, Hontecillas R.

Viral Immunol. 2010 Aug;23(4):343-52. doi: 10.1089/vim.2010.0016. Review.

PMID:
20712478
25.

Blumeria graminis interactions with barley conditioned by different single R genes demonstrate a temporal and spatial relationship between stomatal dysfunction and cell death.

Prats E, Gay AP, Roberts PC, Thomas BJ, Sanderson R, Paveley N, Lyngkjaer MF, Carver TL, Mur LA.

Phytopathology. 2010 Jan;100(1):21-32. doi: 10.1094/PHYTO-100-1-0021.

26.
27.

A novel method to incorporate bioactive cytokines as adjuvants on the surface of virus particles.

Yang Y, Leggat D, Herbert A, Roberts PC, Sundick RS.

J Interferon Cytokine Res. 2009 Jan;29(1):9-22. doi: 10.1089/jir.2008.0017.

28.

Regulation of beta-catenin and connexin-43 expression: targets for sphingolipids in colon cancer prevention.

Simon KW, Roberts PC, Vespremi MJ, Manchen S, Schmelz EM.

Mol Nutr Food Res. 2009 Mar;53(3):332-40. doi: 10.1002/mnfr.200800102.

29.

Gene expression microarray data analysis demystified.

Roberts PC.

Biotechnol Annu Rev. 2008;14:29-61. doi: 10.1016/S1387-2656(08)00002-1. Review.

PMID:
18606359
30.

Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts.

Li Q, Tang L, Roberts PC, Kraniak JM, Fridman AL, Kulaeva OI, Tehrani OS, Tainsky MA.

Mol Cancer Res. 2008 May;6(5):770-84. doi: 10.1158/1541-7786.MCR-07-0114.

31.

Characterization of a subset of bone marrow-derived natural killer cells that regulates T cell activation in rats.

Kheradmand T, Trivedi PP, Wolf NA, Roberts PC, Swanborg RH.

J Leukoc Biol. 2008 May;83(5):1128-35. doi: 10.1189/jlb.0907626. Epub 2008 Feb 13.

PMID:
18272589
32.

Filamentous influenza A virus infection predisposes mice to fatal septicemia following superinfection with Streptococcus pneumoniae serotype 3.

Speshock JL, Doyon-Reale N, Rabah R, Neely MN, Roberts PC.

Infect Immun. 2007 Jun;75(6):3102-11. Epub 2007 Apr 2.

33.

Regulation of adaptive immunity by cells of the innate immune system: bone marrow natural killer cells inhibit T cell proliferation.

Trivedi PP, Amouzegar TK, Roberts PC, Wolf NA, Swanborg RH.

Adv Exp Med Biol. 2007;590:113-20. Review. No abstract available.

PMID:
17191381
34.

Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

Fridman AL, Tang L, Kulaeva OI, Ye B, Li Q, Nahhas F, Roberts PC, Land SJ, Abrams J, Tainsky MA.

J Gerontol A Biol Sci Med Sci. 2006 Sep;61(9):879-89.

PMID:
16960018
35.

Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization.

Tang L, Roberts PC, Kraniak JM, Li Q, Tainsky MA.

J Interferon Cytokine Res. 2006 Jan;26(1):14-26.

PMID:
16426144
36.

Induced inaccessibility and accessibility in the oat powdery mildew system: insights gained from use of metabolic inhibitors and silicon nutrition.

Prats E, Carver TL, Lyngkjær MF, Roberts PC, Zeyen RJ.

Mol Plant Pathol. 2006 Jan 1;7(1):47-59. doi: 10.1111/j.1364-3703.2005.00315.x.

PMID:
20507427
37.

Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.

Roberts PC, Mottillo EP, Baxa AC, Heng HH, Doyon-Reale N, Gregoire L, Lancaster WD, Rabah R, Schmelz EM.

Neoplasia. 2005 Oct;7(10):944-56.

38.

NK cells inhibit T cell proliferation via p21-mediated cell cycle arrest.

Trivedi PP, Roberts PC, Wolf NA, Swanborg RH.

J Immunol. 2005 Apr 15;174(8):4590-7.

39.

Spontaneous malignant transformation of human ovarian surface epithelial cells in vitro.

Gregoire L, Rabah R, Schmelz EM, Munkarah A, Roberts PC, Lancaster WD.

Clin Cancer Res. 2001 Dec;7(12):4280-7.

40.

Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids.

Schmelz EM, Roberts PC, Kustin EM, Lemonnier LA, Sullards MC, Dillehay DL, Merrill AH Jr.

Cancer Res. 2001 Sep 15;61(18):6723-9.

41.

Scanning laser Doppler is a useful technique to assess foot cutaneous perfusion during femoral artery cannulation.

Boyle NH, Roberts PC, Ng B, Berkenstadt H, McLuckie A, Beale RJ, Mason RC.

Crit Care. 1999;3(4):95-100.

42.

Evaluation of the 5-French saline paediatric gastric tonometer.

Thorburn K, Hatherill M, Roberts PC, Durward A, Tibby SM, Murdoch IA.

Intensive Care Med. 2000 Jul;26(7):973-80.

PMID:
10990115
43.

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.

Balachandran S, Roberts PC, Brown LE, Truong H, Pattnaik AK, Archer DR, Barber GN.

Immunity. 2000 Jul;13(1):129-41.

44.

Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway.

Balachandran S, Roberts PC, Kipperman T, Bhalla KN, Compans RW, Archer DR, Barber GN.

J Virol. 2000 Feb;74(3):1513-23.

45.

Oligonucleotide-based inhibition of embryonic gene expression.

Driver SE, Robinson GS, Flanagan J, Shen W, Smith LE, Thomas DW, Roberts PC.

Nat Biotechnol. 1999 Dec;17(12):1184-7.

PMID:
10585715
46.

Gastric intramucosal acidosis in mechanically ventilated patients: role of mucosal blood flow.

Boyle NH, Roberts PC, McLuckie A, Mason RC, Beale RJ.

Crit Care Med. 1999 Nov;27(11):2601-2. No abstract available.

PMID:
10579304
47.
48.

Host cell dependence of viral morphology.

Roberts PC, Compans RW.

Proc Natl Acad Sci U S A. 1998 May 12;95(10):5746-51.

49.

Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases.

Schmelz EM, Dombrink-Kurtzman MA, Roberts PC, Kozutsumi Y, Kawasaki T, Merrill AH Jr.

Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

PMID:
9473533
50.

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