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Respiratory syncytial virus suppression of the antiviral immune response: Implications for evaluation of candidate vaccines.

Roberts NJ Jr.

Vaccine. 2019 Dec 3;37(51):7451-7454. doi: 10.1016/j.vaccine.2019.09.096. Epub 2019 Oct 10. Review.


Biphenotypic Differentiation of Pancreatic Cancer in 3-Dimensional Culture.

Matsushita Y, Smith B, Delannoy M, Trujillo MA, Chianchiano P, McMillan R, Kamiyama H, Liang H, Thompson ED, Hruban RH, Matsui W, Wood LD, Roberts NJ, Eshleman JR.

Pancreas. 2019 Oct;48(9):1225-1231. doi: 10.1097/MPA.0000000000001390.


Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence.

Tomasetti C, Poling J, Roberts NJ, London NR Jr, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20482-20488. doi: 10.1073/pnas.1905722116. Epub 2019 Sep 23.


Risk Factors for Severe Alcohol Withdrawal Syndrome in an Acute Hospital Population.

Benson G, McCallum J, Roberts NJ.

J Addict Nurs. 2019 Jul/Sep;30(3):159-168. doi: 10.1097/JAN.0000000000000287.


A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.

Wong C, Chen F, Alirezaie N, Wang Y, Cuggia A, Borgida A, Holter S, Lenko T, Domecq C; Alzheimer’s Disease Neuroimaging Initiative, Petersen GM, Syngal S, Brand R, Rustgi AK, Cote ML, Stoffel E, Olson SH, Roberts NJ, Akbari MR, Majewski J, Klein AP, Greenwood CMT, Gallinger S, Zogopoulos G.

PLoS Genet. 2019 Aug 30;15(8):e1008344. doi: 10.1371/journal.pgen.1008344. eCollection 2019 Aug.


A Novel Hierarchical LATER Process Model: Evaluating Latent Sources of Variation in Reaction Times of Adult Daily Smokers.

Roberts NJ, Oravecz Z, Sprague BN, Geier CF.

Front Psychiatry. 2019 Jul 5;10:474. doi: 10.3389/fpsyt.2019.00474. eCollection 2019.


Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants.

Hutchings D, Jiang Z, Skaro M, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Zheng L, Klimstra DS, Brand RE, Singhi AD, Goggins M, Klein AP, Roberts NJ, Hruban RH.

Mod Pathol. 2019 Dec;32(12):1806-1813. doi: 10.1038/s41379-019-0317-6. Epub 2019 Jul 8.


The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis.

Nichols JE, Niles JA, Fleming EH, Roberts NJ.

Virology. 2019 Aug;534:80-86. doi: 10.1016/j.virol.2019.06.001. Epub 2019 Jun 10.


Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.

Fischer CG, Beleva Guthrie V, Braxton AM, Zheng L, Wang P, Song Q, Griffin JF, Chianchiano PE, Hosoda W, Niknafs N, Springer S, Dal Molin M, Masica D, Scharpf RB, Thompson ED, He J, Wolfgang CL, Hruban RH, Roberts NJ, Lennon AM, Jiao Y, Karchin R, Wood LD.

Gastroenterology. 2019 Oct;157(4):1123-1137.e22. doi: 10.1053/j.gastro.2019.06.001. Epub 2019 Jun 5.


Prevalence of Germline Mutations Associated With Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms.

Skaro M, Nanda N, Gauthier C, Felsenstein M, Jiang Z, Qiu M, Shindo K, Yu J, Hutchings D, Javed AA, Beckman R, He J, Wolfgang CL, Thompson E, Hruban RH, Klein AP, Goggins M, Wood LD, Roberts NJ.

Gastroenterology. 2019 May;156(6):1905-1913. doi: 10.1053/j.gastro.2019.01.254. Epub 2019 Feb 1.


The acceptability of screening for Carbapenemase Producing Enterobacteriaceae (CPE): cross-sectional survey of nursing staff and the general publics' perceptions.

Currie K, King C, McAloney-Kocaman K, Roberts NJ, MacDonald J, Dickson A, Cairns S, Khanna N, Flowers P, Reilly J, Price L.

Antimicrob Resist Infect Control. 2018 Nov 23;7:144. doi: 10.1186/s13756-018-0434-x. eCollection 2018.


A systematic review of the content and delivery of education in pulmonary rehabilitation programmes.

Roberts NJ, Kidd L, Kirkwood K, Cross J, Partridge MR.

Respir Med. 2018 Dec;145:161-181. doi: 10.1016/j.rmed.2018.11.002. Epub 2018 Nov 5.


Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.

Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD.

J Pathol. 2019 Mar;247(3):347-356. doi: 10.1002/path.5194. Epub 2019 Jan 16.


Food or money? Children's brains respond differently to rewards regardless of weight status.

Adise S, Geier CF, Roberts NJ, White CN, Keller KL.

Pediatr Obes. 2019 Feb;14(2):e12469. doi: 10.1111/ijpo.12469. Epub 2018 Sep 21.


Influenza Virus Infection of Human Lymphocytes Occurs in the Immune Cell Cluster of the Developing Antiviral Response.

Mock DJ, Frampton MW, Nichols JE, Domurat FM, Signs DJ, Roberts NJ Jr.

Viruses. 2018 Aug 10;10(8). pii: E420. doi: 10.3390/v10080420.


Barriers and enablers to meticillin-resistant Staphylococcus aureus admission screening in hospitals: a mixed-methods study.

Currie K, King C, McAloney-Kocaman K, Roberts NJ, MacDonald J, Dickson A, Cairns S, Khanna N, Flowers P, Reilly J, Price L.

J Hosp Infect. 2019 Jan;101(1):100-108. doi: 10.1016/j.jhin.2018.08.006. Epub 2018 Aug 8.


Lithostratigraphic and magnetostratigraphic data from late Cenozoic glacial and proglacial sequences underlying the Altiplano at La Paz, Bolivia.

Roberts NJ, Barendregt RW, Clague JJ.

Data Brief. 2018 May 19;19:965-987. doi: 10.1016/j.dib.2018.05.038. eCollection 2018 Aug.


Is brain response to food rewards related to overeating? A test of the reward surfeit model of overeating in children.

Adise S, Geier CF, Roberts NJ, White CN, Keller KL.

Appetite. 2018 Sep 1;128:167-179. doi: 10.1016/j.appet.2018.06.014. Epub 2018 Jun 8.


Whole-exome sequencing of duodenal neuroendocrine tumors in patients with neurofibromatosis type 1.

Noë M, Pea A, Luchini C, Felsenstein M, Barbi S, Bhaijee F, Yonescu R, Ning Y, Adsay NV, Zamboni G, Lawlor RT, Scarpa A, Offerhaus GJA, Brosens LAA, Hruban RH, Roberts NJ, Wood LD.

Mod Pathol. 2018 Oct;31(10):1532-1538. doi: 10.1038/s41379-018-0082-y. Epub 2018 May 30.


Reflections on integrated care from those working in and leading integrated respiratory teams.

Roberts NJ, Ward M, Patel I, Yorke J, Partridge MR.

London J Prim Care (Abingdon). 2018 Jan 1;10(2):24-30. doi: 10.1080/17571472.2017.1421020. eCollection 2018 Mar.


Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology.

Noë M, Rezaee N, Asrani K, Skaro M, Groot VP, Wu PH, Olson MT, Hong SM, Kim SJ, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wirtz D, Roberts NJ, Offerhaus GJA, Brosens LAA, Wood LD, Hruban RH.

Am J Pathol. 2018 Jul;188(7):1530-1535. doi: 10.1016/j.ajpath.2018.04.002. Epub 2018 Apr 22.


Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4767-4772. doi: 10.1073/pnas.1720588115. Epub 2018 Apr 18.


IPMNs with co-occurring invasive cancers: neighbours but not always relatives.

Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD.

Gut. 2018 Sep;67(9):1652-1662. doi: 10.1136/gutjnl-2017-315062. Epub 2018 Mar 2.


Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action.

Posadzki PP, Bajpai R, Kyaw BM, Roberts NJ, Brzezinski A, Christopoulos GI, Divakar U, Bajpai S, Soljak M, Dunleavy G, Jarbrink K, Nang EEK, Soh CK, Car J.

BMC Med. 2018 Feb 5;16(1):18. doi: 10.1186/s12916-017-1000-8.


Inherited pancreatic cancer.

Chen F, Roberts NJ, Klein AP.

Chin Clin Oncol. 2017 Dec;6(6):58. doi: 10.21037/cco.2017.12.04. Review.


Exome-Wide Association Study of Pancreatic Cancer Risk.

Grant RC, Denroche RE, Borgida A, Virtanen C, Cook N, Smith AL, Connor AA, Wilson JM, Peterson G, Roberts NJ, Klein AP, Grimmond SM, Biankin A, Cleary S, Moore M, Lemire M, Zogopoulos G, Stein L, Gallinger S.

Gastroenterology. 2018 Feb;154(3):719-722.e3. doi: 10.1053/j.gastro.2017.10.015. Epub 2017 Oct 24.



Hawkes NP, Kolkowski P, Roberts NJ, Salvador-Castiñeira P, Taylor GC, Thomas DJ.

Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):25-28. doi: 10.1093/rpd/ncx191.



Roberts NJ.

Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):62-65. doi: 10.1093/rpd/ncx172.


Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus.

Fleming EH, Ochoa EE, Nichols JE, O'Banion MK, Salkind AR, Roberts NJ Jr.

J Med Virol. 2018 Jan;90(1):26-33. doi: 10.1002/jmv.24917. Epub 2017 Sep 26.


Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.

Shindo K, Yu J, Suenaga M, Fesharakizadeh S, Cho C, Macgregor-Das A, Siddiqui A, Witmer PD, Tamura K, Song TJ, Navarro Almario JA, Brant A, Borges M, Ford M, Barkley T, He J, Weiss MJ, Wolfgang CL, Roberts NJ, Hruban RH, Klein AP, Goggins M.

J Clin Oncol. 2017 Oct 20;35(30):3382-3390. doi: 10.1200/JCO.2017.72.3502. Epub 2017 Aug 2.


Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism.

Summers EL, Cumming MH, Oulavallickal T, Roberts NJ, Arcus VL.

Protein Sci. 2017 Aug;26(8):1627-1638. doi: 10.1002/pro.3199. Epub 2017 Jun 6.


Multiple tropical Andean glaciations during a period of late Pliocene warmth.

Roberts NJ, Barendregt RW, Clague JJ.

Sci Rep. 2017 Feb 7;7:41878. doi: 10.1038/srep41878.


Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD.

Price KE, Armstrong CM, Imlay LS, Hodge DM, Pidathala C, Roberts NJ, Park J, Mikati M, Sharma R, Lawrenson AS, Tolia NH, Berry NG, O'Neill PM, John AR.

Sci Rep. 2016 Nov 18;6:36777. doi: 10.1038/srep36777.


Metastatic recurrence to a solitary lymph node four years after hepatic lobectomy for primary hepatocellular carcinoma.

Caparelli ML, Roberts NJ, Braverman TS, Stevens RM, Broun ER, Allamaneni S.

World J Hepatol. 2016 Aug 18;8(23):994-8. doi: 10.4254/wjh.v8.i23.994.


Human Alveolar Macrophages May Not Be Susceptible to Direct Infection by a Human Influenza Virus.

Ettensohn DB, Frampton MW, Nichols JE, Roberts NJ Jr.

J Infect Dis. 2016 Dec 1;214(11):1658-1665. Epub 2016 Sep 6.


Aristolochic Acid in the Etiology of Renal Cell Carcinoma.

Hoang ML, Chen CH, Chen PC, Roberts NJ, Dickman KG, Yun BH, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA.

Cancer Epidemiol Biomarkers Prev. 2016 Dec;25(12):1600-1608. Epub 2016 Aug 23.


Measuring patient activation: The utility of the Patient Activation Measure within a UK context-Results from four exemplar studies and potential future applications.

Roberts NJ, Kidd L, Dougall N, Patel IS, McNarry S, Nixon C.

Patient Educ Couns. 2016 Oct;99(10):1739-46. doi: 10.1016/j.pec.2016.05.006. Epub 2016 May 9.


Clostridium novyi-NT in cancer therapy.

Staedtke V, Roberts NJ, Bai RY, Zhou S.

Genes Dis. 2016 Feb 6;3(2):144-152. doi: 10.1016/j.gendis.2016.01.003. eCollection 2016 Jun. Review.


Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, Papadopoulos N.

Gastroenterology. 2016 Apr;150(4):931-43. doi: 10.1053/j.gastro.2015.12.036. Epub 2016 Jan 5.


The diagnosis of COPD in primary care; gender differences and the role of spirometry.

Roberts NJ, Patel IS, Partridge MR.

Respir Med. 2016 Feb;111:60-3. doi: 10.1016/j.rmed.2015.12.008. Epub 2015 Dec 19.


Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP.

Cancer Discov. 2016 Feb;6(2):166-75. doi: 10.1158/2159-8290.CD-15-0402. Epub 2015 Dec 9.


Multimodal secondary prevention behavioral interventions for TIA and stroke: a systematic review and meta-analysis.

Lawrence M, Pringle J, Kerr S, Booth J, Govan L, Roberts NJ.

PLoS One. 2015 Mar 20;10(3):e0120902. doi: 10.1371/journal.pone.0120902. eCollection 2015. Review.


Reduced Influence of Monetary Incentives on Go/NoGo Performance During Smoking Abstinence.

Lydon DM, Roberts NJ, Geier CF.

Nicotine Tob Res. 2015 Sep;17(9):1178-81. doi: 10.1093/ntr/ntu283. Epub 2014 Dec 26.


BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.

Zhen DB, Rabe KG, Gallinger S, Syngal S, Schwartz AG, Goggins MG, Hruban RH, Cote ML, McWilliams RR, Roberts NJ, Cannon-Albright LA, Li D, Moyes K, Wenstrup RJ, Hartman AR, Seminara D, Klein AP, Petersen GM.

Genet Med. 2015 Jul;17(7):569-77. doi: 10.1038/gim.2014.153. Epub 2014 Nov 20.


Familial and sporadic pancreatic cancer share the same molecular pathogenesis.

Norris AL, Roberts NJ, Jones S, Wheelan SJ, Papadopoulos N, Vogelstein B, Kinzler KW, Hruban RH, Klein AP, Eshleman JR.

Fam Cancer. 2015 Mar;14(1):95-103. doi: 10.1007/s10689-014-9755-y.


Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses.

Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, Bird JE, Roy-Chowdhuri S, Zhang HH, Qiao Y, Karim B, McDaniel J, Elpiner A, Sahora A, Lachowicz J, Phillips B, Turner A, Klein MK, Post G, Diaz LA Jr, Riggins GJ, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C, Huso DL, Varterasian M, Saha S, Zhou S.

Sci Transl Med. 2014 Aug 13;6(249):249ra111. doi: 10.1126/scitranslmed.3008982.


Clinical simulation: dare we venture into the uncanny valley?

Roberts D, Roberts NJ.

Nurse Educ Pract. 2014 May;14(3):225-6. doi: 10.1016/j.nepr.2014.04.002. Epub 2014 Apr 24. No abstract available.


Investigation of a Mycobacterium bovis outbreak in cattle at a Colorado dairy in 2010.

Francisco TI, Orloski KA, Roberts NJ.

J Am Vet Med Assoc. 2014 Apr 1;244(7):805-12. doi: 10.2460/javma.244.7.805.


A review of halotherapy for chronic obstructive pulmonary disease.

Rashleigh R, Smith SM, Roberts NJ.

Int J Chron Obstruct Pulmon Dis. 2014 Feb 21;9:239-46. doi: 10.2147/COPD.S57511. eCollection 2014. Review.


Time to recognise sexual orientation as a social determinant of health.

Horner J, Roberts NJ.

Med J Aust. 2014 Feb 17;200(3):137. No abstract available.


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