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Quality by Design: Development of the Quality Target Product Profile (QTPP) for Semisolid Topical Products.

Namjoshi S, Dabbaghi M, Roberts MS, Grice JE, Mohammed Y.

Pharmaceutics. 2020 Mar 23;12(3). pii: E287. doi: 10.3390/pharmaceutics12030287. Review.


The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: Data from the multinational SMARRT Study.

Roberts JA, Joynt G, Lee A, Choi G, Bellomo R, Kanji S, Mudaliar MY, Peake SL, Stephens D, Taccone FS, Ulldemolins M, Valkonen MM, Agbeve J, Baptista JP, Bekos V, Boidin C, Brinkmann A, Buizen L, Castro P, Cole CL, Creteur J, De Waele JJ, Deans R, Eastwood GM, Escobar L, Gomersall C, Gresham R, Jamal JA, Kluge S, König C, Koulouras VP, Lassig-Smith M, Laterre PF, Lei K, Leung P, Lefrant JY, Llauradó-Serra M, Martin-Loeches I, Mat Nor MB, Ostermann M, Parker SL, Rello J, Roberts DM, Roberts MS, Richards B, Rodríguez A, Roehr AC, Roger C, Seoane L, Sinnollareddy M, Sousa E, Soy D, Spring A, Starr T, Thomas J, Turnidge J, Wallis SC, Williams T, Wittebole X, Zikou XT, Paul S, Lipman J.

Clin Infect Dis. 2020 Mar 9. pii: ciaa224. doi: 10.1093/cid/ciaa224. [Epub ahead of print]


LIN9 and NEK2 are core regulators of mitotic fidelity that can be therapeutically targeted to overcome taxane resistance.

Roberts MS, Sahni JM, Schrock MS, Piemonte KM, Weber-Bonk KL, Seachrist DD, Avril S, Anstine LJ, Singh S, Sizemore ST, Varadan V, Summers MK, Keri RA.

Cancer Res. 2020 Feb 13. pii: canres.3466.2019. doi: 10.1158/0008-5472.CAN-19-3466. [Epub ahead of print]


Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose.

Liu X, Yousef S, Anissimov YG, van der Hoek J, Tsakalozou E, Ni Z, Grice JE, Roberts MS.

Eur J Pharm Biopharm. 2020 Apr;149:30-44. doi: 10.1016/j.ejpb.2020.01.018. Epub 2020 Feb 1.


Prevalence and Factors Associated with Analgesic Prescribing in Poly-Medicated Elderly Patients.

Al-Qurain AA, Gebremichael LG, Khan MS, Williams DB, Mackenzie L, Phillips C, Russell P, Roberts MS, Wiese MD.

Drugs Aging. 2020 Apr;37(4):291-300. doi: 10.1007/s40266-019-00742-0.


Novel Nanocarriers for Targeted Topical Skin Delivery of the Antioxidant Resveratrol.

Nastiti CMRR, Ponto T, Mohammed Y, Roberts MS, Benson HAE.

Pharmaceutics. 2020 Jan 29;12(2). pii: E108. doi: 10.3390/pharmaceutics12020108.


Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma.

Ruan Q, Wang H, Burke LJ, Bridle KR, Li X, Zhao CX, Crawford DHG, Roberts MS, Liang X.

Int J Cancer. 2020 Feb 3. doi: 10.1002/ijc.32899. [Epub ahead of print] Review.


Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis.

Holmes AM, Mackenzie L, Roberts MS.

Nanotoxicology. 2020 Mar;14(2):263-274. doi: 10.1080/17435390.2019.1692382. Epub 2020 Jan 31.


Bathing Does Not Facilitate Human Skin Penetration or Adverse Cellular Effects of Nanoparticulate Zinc Oxide Sunscreens after Topical Application.

Mohammed YH, Haridass IN, Grice JE, Benson HAE, Roberts MS.

J Invest Dermatol. 2020 Jan 21. pii: S0022-202X(20)30037-3. doi: 10.1016/j.jid.2019.12.024. [Epub ahead of print] No abstract available.


Mechanistic Evaluation of Enhanced Curcumin Delivery through Human Skin In Vitro from Optimised Nanoemulsion Formulations Fabricated with Different Penetration Enhancers.

Yousef SA, Mohammed YH, Namjoshi S, Grice JE, Benson HAE, Sakran W, Roberts MS.

Pharmaceutics. 2019 Dec 1;11(12). pii: E639. doi: 10.3390/pharmaceutics11120639.


Improved Health Outcomes from Hepatitis C Treatment Scale-Up in Spain's Prisons: A Cost-Effectiveness Study.

Dalgic OO, Samur S, Spaulding AC, Llerena S, Cobo C, Ayer T, Roberts MS, Crespo J, Chhatwal J.

Sci Rep. 2019 Nov 14;9(1):16849. doi: 10.1038/s41598-019-52564-0.


Advancing BSNs by 2020: Innovative Educational Progression for Success.

Roberts MS, Gapp DK, Burns-Coral M, Greaves VD, Williams ML.

Nurs Educ Perspect. 2019 Oct 11. doi: 10.1097/01.NEP.0000000000000579. [Epub ahead of print]


Designer artificial membrane binding proteins to direct stem cells to the myocardium.

Xiao W, Green TIP, Liang X, Delint RC, Perry G, Roberts MS, Le Vay K, Back CR, Ascione R, Wang H, Race PR, Perriman AW.

Chem Sci. 2019 Jul 3;10(32):7610-7618. doi: 10.1039/c9sc02650a. eCollection 2019 Aug 28.


Targeted Topical Delivery of Retinoids in the Management of Acne Vulgaris: Current Formulations and Novel Delivery Systems.

Latter G, Grice JE, Mohammed Y, Roberts MS, Benson HAE.

Pharmaceutics. 2019 Sep 24;11(10). pii: E490. doi: 10.3390/pharmaceutics11100490. Review.


Exclusion Criteria as Measurements II: Effects on Utility Functions.

Dewitt B, Fischhoff B, Davis AL, Broomell SB, Roberts MS, Hanmer J.

Med Decis Making. 2019 Aug;39(6):704-716. doi: 10.1177/0272989X19862542. Epub 2019 Aug 28.


Exclusion Criteria as Measurements I: Identifying Invalid Responses.

Dewitt B, Fischhoff B, Davis AL, Broomell SB, Roberts MS, Hanmer J.

Med Decis Making. 2019 Aug;39(6):693-703. doi: 10.1177/0272989X19856617. Epub 2019 Aug 28.


Forecasted Size of Measles Outbreaks Associated With Vaccination Exemptions for Schoolchildren.

Sinclair DR, Grefenstette JJ, Krauland MG, Galloway DD, Frankeny RJ, Travis C, Burke DS, Roberts MS.

JAMA Netw Open. 2019 Aug 2;2(8):e199768. doi: 10.1001/jamanetworkopen.2019.9768.


Molecular Testing Versus Diagnostic Lobectomy in Bethesda III/IV Thyroid Nodules: A Cost-Effectiveness Analysis.

Nicholson KJ, Roberts MS, McCoy KL, Carty SE, Yip L.

Thyroid. 2019 Sep;29(9):1237-1243. doi: 10.1089/thy.2018.0779.


Impact of Age on Risk of Lymph Node Positivity in Patients with Colon Cancer.

Wang H, Lu H, Yang H, Zhang X, Thompson EW, Roberts MS, Hu Z, Liang X, Li X.

J Cancer. 2019 May 12;10(9):2102-2108. doi: 10.7150/jca.28377. eCollection 2019.


Cellular metabolism and pore lifetime of human skin following microprojection array mediation.

Haridass IN, Wei JCJ, Mohammed YH, Crichton ML, Anderson CD, Henricson J, Sanchez WY, Meliga SC, Grice JE, Benson HAE, Kendall MAF, Roberts MS.

J Control Release. 2019 Jul 28;306:59-68. doi: 10.1016/j.jconrel.2019.05.024. Epub 2019 May 21.


Evaluation of Quantum Dot Skin Penetration in Porcine Skin: Effect of Age and Anatomical Site of Topical Application.

Nastiti CMRR, Mohammed Y, Telaprolu KC, Liang X, Grice JE, Roberts MS, Benson HAE.

Skin Pharmacol Physiol. 2019;32(4):182-191. doi: 10.1159/000499435. Epub 2019 May 14.


Treatment of Autosomal Dominant Hypocalcemia Type 1 With the Calcilytic NPSP795 (SHP635).

Roberts MS, Gafni RI, Brillante B, Guthrie LC, Streit J, Gash D, Gelb J, Krusinska E, Brennan SC, Schepelmann M, Riccardi D, Bin Khayat ME, Ward DT, Nemeth EF, Rosskamp R, Collins MT.

J Bone Miner Res. 2019 Sep;34(9):1609-1618. doi: 10.1002/jbmr.3747. Epub 2019 Jul 26.


Permeation Mechanism of Caffeine and Naproxen through in vitro Human Epidermis: Effect of Vehicles and Penetration Enhancers.

Abd E, Benson HAE, Mohammed YH, Roberts MS, Grice JE.

Skin Pharmacol Physiol. 2019;32(3):132-141. doi: 10.1159/000497225. Epub 2019 Mar 25.


Optical Characterization of Zinc Pyrithione.

Sandiford L, Holmes AM, Mangion SE, Mohammed YH, Zvyagin AV, Roberts MS.

Photochem Photobiol. 2019 Sep;95(5):1142-1150. doi: 10.1111/php.13100. Epub 2019 Apr 22.


Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies.

Benson HAE, Grice JE, Mohammed Y, Namjoshi S, Roberts MS.

Curr Drug Deliv. 2019;16(5):444-460. doi: 10.2174/1567201816666190201143457. Review.


Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice.

Jin W, Liang X, Brooks A, Futrega K, Liu X, Doran MR, Simpson MJ, Roberts MS, Wang H.

PeerJ. 2018 Dec 6;6:e6072. doi: 10.7717/peerj.6072. eCollection 2018.


Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays.

Wei JCJ, Haridass IN, Crichton ML, Mohammed YH, Meliga SC, Sanchez WY, Grice JE, Benson HAE, Roberts MS, Kendall MAF.

Sci Rep. 2018 Dec 10;8(1):17759. doi: 10.1038/s41598-018-36009-8.


Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster.

Rainsford KD, Roberts MS, Nencioni A, Jones C.

Curr Med Res Opin. 2019 Jun;35(6):989-1002. doi: 10.1080/03007995.2018.1551194. Epub 2018 Dec 20.


Anionic Long-Circulating Quantum Dots for Long-Term Intravital Vascular Imaging.

Wang H, Yang H, Xu ZP, Liu X, Roberts MS, Liang X.

Pharmaceutics. 2018 Nov 20;10(4). pii: E244. doi: 10.3390/pharmaceutics10040244.


Support for the Safe Use of Zinc Oxide Nanoparticle Sunscreens: Lack of Skin Penetration or Cellular Toxicity after Repeated Application in Volunteers.

Mohammed YH, Holmes A, Haridass IN, Sanchez WY, Studier H, Grice JE, Benson HAE, Roberts MS.

J Invest Dermatol. 2019 Feb;139(2):308-315. doi: 10.1016/j.jid.2018.08.024. Epub 2018 Nov 15.


The Antioxidant Activity of Recombinant Rat Hepatic Fatty Acid Binding Protein T94A Variant.

Le T, Gong Y, Davies NM, Lillico R, Lakowski T, Roberts MS, Burczynski FJ.

J Pharm Pharm Sci. 2018;21(1s):309s-324s. doi: 10.18433/jpps30246.


The role of cellular reactive oxygen species in cancer chemotherapy.

Yang H, Villani RM, Wang H, Simpson MJ, Roberts MS, Tang M, Liang X.

J Exp Clin Cancer Res. 2018 Nov 1;37(1):266. doi: 10.1186/s13046-018-0909-x. Review.


ZnO:SBA-15 Nanocomposites for Potential Use in Sunscreen: Preparation, Properties, Human Skin Penetration and Toxicity.

Vieira CO, Grice JE, Roberts MS, Haridass IN, Duque MD, Lopes PS, Leite-Silva VR, Martins TS.

Skin Pharmacol Physiol. 2019;32(1):32-42. doi: 10.1159/000491758. Epub 2018 Oct 31.


Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis.

Abraham J, Sinnollareddy MG, Roberts MS, Williams P, Peake SL, Lipman J, Roberts JA.

Int J Antimicrob Agents. 2019 Feb;53(2):137-142. doi: 10.1016/j.ijantimicag.2018.09.021. Epub 2018 Oct 5.


Response to 'Comment on ''Massive' metformin overdose' by Chiew et al.'

Chiew AL, Wright DFB, Roberts MS, Isbister GK.

Br J Clin Pharmacol. 2018 Dec;84(12):2940-2941. doi: 10.1111/bcp.13747. Epub 2018 Oct 2. No abstract available.


Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography.

Alahakoon C, Dassanayake TL, Gawarammana IB, Sedgwick EM, Weerasinghe VS, Abdalla A, Roberts MS, Buckley NA.

PLoS One. 2018 Sep 27;13(9):e0203596. doi: 10.1371/journal.pone.0203596. eCollection 2018.


Accuracy of the Pediatric End-stage Liver Disease Score in Estimating Pretransplant Mortality Among Pediatric Liver Transplant Candidates.

Chang CH, Bryce CL, Shneider BL, Yabes JG, Ren Y, Zenarosa GL, Tomko H, Donnell DM, Squires RH, Roberts MS.

JAMA Pediatr. 2018 Nov 1;172(11):1070-1077. doi: 10.1001/jamapediatrics.2018.2541.


Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016.

Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS.

Science. 2018 Sep 21;361(6408). pii: eaau1184. doi: 10.1126/science.aau1184.


Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers.

Yamada M, Tayeb H, Wang H, Dang N, Mohammed YH, Osseiran S, Belt PJ, Roberts MS, Evans CL, Sainsbury F, Prow TW.

J Control Release. 2018 Oct 28;288:264-276. doi: 10.1016/j.jconrel.2018.09.012. Epub 2018 Sep 15.


Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies.

Roberts MS, Burbelo PD, Egli-Spichtig D, Perwad F, Romero CJ, Ichikawa S, Farrow E, Econs MJ, Guthrie LC, Collins MT, Gafni RI.

J Clin Invest. 2018 Dec 3;128(12):5368-5373. doi: 10.1172/JCI122004. Epub 2018 Oct 29.


Challenges and innovations of drug delivery in older age.

Khan MS, Roberts MS.

Adv Drug Deliv Rev. 2018 Oct;135:3-38. doi: 10.1016/j.addr.2018.09.003. Epub 2018 Sep 11. Review.


Multilineage ACTB mutation in a patient with fibro-osseous maxillary lesion and pilocytic astrocytoma.

Lim YH, Burke AB, Roberts MS, Collins MT, Choate KA.

Am J Med Genet A. 2018 Sep;176(9):2037-2040. doi: 10.1002/ajmg.a.40475. Epub 2018 Aug 27. No abstract available.


Cost Effectiveness of Transplanting HCV-Infected Livers Into Uninfected Recipients With Preemptive Antiviral Therapy.

Bethea ED, Samur S, Kanwal F, Ayer T, Hur C, Roberts MS, Terrault N, Chung RT, Chhatwal J.

Clin Gastroenterol Hepatol. 2019 Mar;17(4):739-747.e8. doi: 10.1016/j.cgh.2018.08.042. Epub 2018 Aug 21.


Compartmental modeling of skin transport.

Amarah AA, Petlin DG, Grice JE, Hadgraft J, Roberts MS, Anissimov YG.

Eur J Pharm Biopharm. 2018 Sep;130:336-344. doi: 10.1016/j.ejpb.2018.07.015. Epub 2018 Jul 19.


Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies.

Abd E, Benson HAE, Roberts MS, Grice JE.

Skin Pharmacol Physiol. 2018;31(5):252-260. doi: 10.1159/000489857. Epub 2018 Jul 12.


Removing physiological motion from intravital and clinical functional imaging data.

Warren SC, Nobis M, Magenau A, Mohammed YH, Herrmann D, Moran I, Vennin C, Conway JR, Mélénec P, Cox TR, Wang Y, Morton JP, Welch HC, Strathdee D, Anderson KI, Phan TG, Roberts MS, Timpson P.

Elife. 2018 Jul 9;7. pii: e35800. doi: 10.7554/eLife.35800.


Estimation of a Preference-Based Summary Score for the Patient-Reported Outcomes Measurement Information System: The PROMIS®-Preference (PROPr) Scoring System.

Dewitt B, Feeny D, Fischhoff B, Cella D, Hays RD, Hess R, Pilkonis PA, Revicki DA, Roberts MS, Tsevat J, Yu L, Hanmer J.

Med Decis Making. 2018 Aug;38(6):683-698. doi: 10.1177/0272989X18776637. Epub 2018 Jun 26.


Skeletal Consequences of Nephropathic Cystinosis.

Florenzano P, Ferreira C, Nesterova G, Roberts MS, Tella SH, de Castro LF, Brown SM, Whitaker A, Pereira RC, Bulas D, Gafni RI, Salusky IB, Gahl WA, Collins MT.

J Bone Miner Res. 2018 Oct;33(10):1870-1880. doi: 10.1002/jbmr.3522. Epub 2018 Jul 20.


Using time-varying models to estimate post-transplant survival in pediatric liver transplant recipients.

Bryce CL, Chang CCH, Ren Y, Yabes J, Zenarosa G, Iyer A, Tomko H, Squires RH, Roberts MS.

PLoS One. 2018 May 31;13(5):e0198132. doi: 10.1371/journal.pone.0198132. eCollection 2018.


Comparison of toxicant load from waterpipe and cigarette tobacco smoking among young adults in the USA.

Primack BA, Shensa A, Sidani JE, Tulikangas MC, Roberts MS, Colditz JB, Mor MK, James AE, Fine MJ.

Tob Control. 2018 May 16. pii: tobaccocontrol-2017-054226. doi: 10.1136/tobaccocontrol-2017-054226. [Epub ahead of print]


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