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Items: 1 to 50 of 2020

1.

Discovery of a potent and selective oral inhibitor of ERK1/2 (AZD0364) that is efficacious in both monotherapy and combination therapy in models of non-small cell lung cancer (NSCLC).

Ward RA, Anderton MJ, Bethel PA, Breed J, Cook C, Davies E, Dobson A, Dong Z, Fairley G, Farrington P, Feron LJ, Flemington V, Gibbons FD, Graham MA, Greenwood RDR, Hanson L, Hopcroft P, Howells R, Hudson J, James M, Jones CD, Jones C, Li Y, Lamont S, Lewis RJ, Lindsay NA, McCabe JF, McGuire TM, Rawlins PB, Roberts K, Sandin L, Simpson I, Swallow S, Tang J, Tomkinson G, Tonge M, Wang Z, Zhai B.

J Med Chem. 2019 Nov 11. doi: 10.1021/acs.jmedchem.9b01295. [Epub ahead of print]

PMID:
31710489
2.

Determining Optimal Routes to Surgery for Borderline Resectable Venous Pancreatic Cancer-Where Is the Least Harm and Most Benefit?

Pandé R, Roberts KJ.

Front Oncol. 2019 Oct 17;9:1060. doi: 10.3389/fonc.2019.01060. eCollection 2019. Review.

3.

Additive manufacturing of platinum group element (PGE) standard reference materials with a silica matrix.

Sio CK, Parsons-Davis T, Lee E, Wimpenny J, Pascall AJ, Kuntz JD, Goodell JJ, Roberts KE, Bandong BB, Bennett NR.

Rapid Commun Mass Spectrom. 2019 Oct 28. doi: 10.1002/rcm.8627. [Epub ahead of print]

PMID:
31658503
4.

The Biology of B-Progenitor Acute Lymphoblastic Leukemia.

Roberts KG, Mullighan CG.

Cold Spring Harb Perspect Med. 2019 Oct 25. pii: a034835. doi: 10.1101/cshperspect.a034835. [Epub ahead of print]

PMID:
31653664
5.

Negative Life Events and Suicide in the National Violent Death Reporting System.

Chen T, Roberts K.

Arch Suicide Res. 2019 Oct 22:1-15. doi: 10.1080/13811118.2019.1677275. [Epub ahead of print]

PMID:
31638469
6.

Evaluation of Force-Field Calculations of Lattice Energies on a Large Public Dataset, Assessment of Pharmaceutical Relevance, and Comparison to Density Functional Theory.

Marchese Robinson RL, Geatches D, Morris C, Mackenzie R, Maloney AGP, Roberts KJ, Moldovan A, Chow E, Pencheva K, Vatvani DRM.

J Chem Inf Model. 2019 Nov 1. doi: 10.1021/acs.jcim.9b00601. [Epub ahead of print]

PMID:
31638394
7.

Health Impact of Hurricanes Irma and Maria on St Thomas and St John, US Virgin Islands, 2017-2018.

Chowdhury MAB, Fiore AJ, Cohen SA, Wheatley C, Wheatley B, Balakrishnan MP, Chami M, Scieszka L, Drabin M, Roberts KA, Toben AC, Tyndall JA, Grattan LM, Morris JG Jr.

Am J Public Health. 2019 Dec;109(12):1725-1732. doi: 10.2105/AJPH.2019.305310. Epub 2019 Oct 17.

PMID:
31622150
8.

A frame semantic overview of NLP-based information extraction for cancer-related EHR notes.

Datta S, Bernstam EV, Roberts K.

J Biomed Inform. 2019 Oct 4;100:103301. doi: 10.1016/j.jbi.2019.103301. [Epub ahead of print] Review.

PMID:
31589927
9.

Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients.

Nurbhai S, Roberts KJ, Carlton TM, Maggiore L, Cubitt MF, Ray KP, Reckless J, Mohammed H, Irving P, MacDonald TT, Vossenkämper A, West MR, Parkes GC, Crowe JS.

Sci Rep. 2019 Oct 1;9(1):14042. doi: 10.1038/s41598-019-50545-x.

10.

Inhibition of Amyloid-β Aggregation by Cobalt(III) Schiff Base Complexes: A Computational and Experimental Approach.

Iscen A, Brue CR, Roberts KF, Kim J, Schatz GC, Meade TJ.

J Am Chem Soc. 2019 Oct 23;141(42):16685-16695. doi: 10.1021/jacs.9b06388. Epub 2019 Oct 10.

PMID:
31573804
11.

Does non-operative management of iatrogenic bile duct injury result in impaired quality of life? A systematic review.

Halle-Smith JM, Hodson J, Stevens L, Mirza DF, Roberts KJ.

Surgeon. 2019 Sep 10. pii: S1479-666X(19)30093-9. doi: 10.1016/j.surge.2019.07.007. [Epub ahead of print] Review.

PMID:
31519430
12.

Qualitative and Quantitative Evaluation of the Make Safe Happen App: Mobile Technology-Based Safety Behavior Change Intervention for Parents.

Roberts KJ, McAdams RJ, Kristel OV, Szymanski AM, McKenzie LB.

JMIR Pediatr Parent. 2019 Mar 14;2(1):e12022. doi: 10.2196/12022.

13.

Jaccoud's arthropathy in SLE: findings from a Latin American multiethnic population.

Quintana R, Pons-Estel G, Roberts K, Sacnún M, Berbotto G, Garcia MA, Saurit V, Barile-Fabris L, Acevedo-Vazquez EM, Tavares Brenol JC, Sato EI, Iglesias A, Uribe O, Alarcon G, Pons-Estel BA.

Lupus Sci Med. 2019 Aug 12;6(1):e000343. doi: 10.1136/lupus-2019-000343. eCollection 2019.

14.

Risk adjusted assessment of individual surgeon's pancreatic fistula outcomes.

Roberts KJ, Boteon APCS, Marcon F, Abradelo M, Dasari B, Muiesan P, Marudanayagam R, Sutcliffe RP, Isaac J, Mirza DF.

HPB (Oxford). 2019 Aug 21. pii: S1365-182X(19)30636-7. doi: 10.1016/j.hpb.2019.07.017. [Epub ahead of print]

PMID:
31445781
15.

Characterization of Behavioral Transitions Through Social Media Analysis: A Mixed-Methods Approach.

Singh T, Perez CA, Roberts K, Cobb N, Franklin A, Myneni S.

Stud Health Technol Inform. 2019 Aug 21;264:1228-1232. doi: 10.3233/SHTI190422.

PMID:
31438121
16.

Epigenetic Defects in the B cell lineage of Systemic Lupus Erythematosus Patients Display Population-Specific Patterns.

Breitbach M, Ramaker RC, Roberts K, Kimberly RP, Absher D.

Arthritis Rheumatol. 2019 Aug 20. doi: 10.1002/art.41083. [Epub ahead of print]

PMID:
31430064
17.

Development and validation of a risk score to predict the overall survival following surgical resection of hepatocellular carcinoma in non-cirrhotic liver.

Dasari BV, Kamarajah SK, Hodson J, Pawlik TM, Vauthey JN, Ma YT, Punia P, Coldham C, Abradelo M, Roberts KJ, Marudanayagam R, Sutcliffe RP, Muiesan P, Mirza DF, Isaac J.

HPB (Oxford). 2019 Aug 12. pii: S1365-182X(19)30621-5. doi: 10.1016/j.hpb.2019.07.007. [Epub ahead of print]

PMID:
31416786
18.

Ultrasensitive Detection of Human Chorionic Gonadotropin Using Frequency Locked Microtoroid Optical Resonators.

Ozgur E, Roberts KE, Ozgur EO, Gin AN, Bankhead JR, Wang Z, Su J.

Anal Chem. 2019 Sep 17;91(18):11872-11878. doi: 10.1021/acs.analchem.9b02630. Epub 2019 Aug 23.

PMID:
31415150
19.

Gastrectomy Alone or in Combination With Hepatic Resection in the Management of Liver Metastases From Gastric Cancer: A Systematic Review Using an Updated and Cumulative Meta-Analysis.

Gavriilidis P, Roberts KJ, de'Angelis N, Sutcliffe RP.

J Clin Med Res. 2019 Aug;11(8):600-608. doi: 10.14740/jocmr3925. Epub 2019 Jul 27.

20.

Simultaneous, Delayed and Liver-First Hepatic Resections for Synchronous Colorectal Liver Metastases: A Systematic Review and Network Meta-Analysis.

Gavriilidis P, Katsanos K, Sutcliffe RP, Simopoulos C, Azoulay D, Roberts KJ.

J Clin Med Res. 2019 Aug;11(8):572-582. doi: 10.14740/jocmr3887. Epub 2019 Jul 27.

21.

Correction: The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity.

Sirey TM, Roberts K, Haerty W, Bedoya-Reina O, Rogatti-Granados S, Tan JY, Li N, Heather LC, Carter RN, Cooper S, Finch AJ, Wills J, Morton NM, Marques AC, Ponting CP.

Elife. 2019 Aug 12;8. pii: e50980. doi: 10.7554/eLife.50980.

22.

Propensity-matched analysis of the influence of perioperative statin therapy on outcomes after liver resection.

Dasari BVM, Pathanki A, Hodson J, Roberts KJ, Marudanayagam R, Mirza DF, Isaac J, Sutcliffe RP, Muiesan P.

BJS Open. 2019 Mar 12;3(4):509-515. doi: 10.1002/bjs5.50155. eCollection 2019 Aug.

23.

Evaluation of the clinical and economic impact of delays to surgery in patients with periampullary cancer.

Pandé R, Hodson J, Murray A, Marcon F, Kalisvaart M, Marudanayagam R, Sutcliffe RP, Mirza DF, Isaac J, Roberts KJ.

BJS Open. 2019 Apr 2;3(4):476-484. doi: 10.1002/bjs5.50161. eCollection 2019 Aug.

24.

Association Between Recurrent Febrile Urinary Tract Infections and Renal Scarring: From Unquestioned Answers to Unanswered Questions.

Roberts KB.

JAMA Pediatr. 2019 Aug 5. doi: 10.1001/jamapediatrics.2019.2509. [Epub ahead of print] No abstract available.

PMID:
31381022
25.

Maternal Knowledge, Attitudes, and Behavioral Intention after Exposure to Injury Prevention Recommendations in the News Media.

McKenzie LB, Roberts KJ, Collins CL, Clark RM, Smith KC, Manganello J.

J Health Commun. 2019 Aug 3:1-8. doi: 10.1080/10810730.2019.1646357. [Epub ahead of print]

PMID:
31378155
26.

Off-the-shelf DFT-DISPersion methods: Are they now "on-trend" for organic molecular crystals?

Geatches D, Rosbottom I, Marchese Robinson RL, Byrne P, Hasnip P, Probert MIJ, Jochym D, Maloney A, Roberts KJ.

J Chem Phys. 2019 Jul 28;151(4):044106. doi: 10.1063/1.5108829.

27.

The Effect of a Low-Cost Body Weight-Supported Treadmill Trainer on Walking Speed and Joint Motion.

Ventura JD, Charrette AL, Roberts KJ.

Medicina (Kaunas). 2019 Jul 30;55(8). pii: E420. doi: 10.3390/medicina55080420.

28.

Discovery of Novel Polymyxin-Like Antibiotics.

Velkov T, Roberts KD.

Adv Exp Med Biol. 2019;1145:343-362. doi: 10.1007/978-3-030-16373-0_20. Review.

PMID:
31364086
29.

History, Chemistry and Antibacterial Spectrum.

Velkov T, Thompson PE, Azad MAK, Roberts KD, Bergen PJ.

Adv Exp Med Biol. 2019;1145:15-36. doi: 10.1007/978-3-030-16373-0_3. Review.

PMID:
31364069
30.

Ventilator-Dependent Patients Successfully Weaned With Cognitive-Behavioral Therapy: A Case Series.

Cohen JN, Gopal A, Roberts KJ, Anderson E, Siegel AM.

Psychosomatics. 2019 Feb 12. pii: S0033-3182(19)30042-8. doi: 10.1016/j.psym.2019.02.003. [Epub ahead of print] No abstract available.

PMID:
31327505
31.

Iodine immobilization by silver-impregnated granular activated carbon in cementitious systems.

Li D, Kaplan DI, Price KA, Seaman JC, Roberts K, Xu C, Lin P, Xing W, Schwehr K, Santschi PH.

J Environ Radioact. 2019 Nov;208-209:106017. doi: 10.1016/j.jenvrad.2019.106017. Epub 2019 Jul 17.

PMID:
31325735
32.

Comparison of self-reported and accelerometer-measured physical activity among Canadian youth.

Colley RC, Butler G, Garriguet D, Prince SA, Roberts KC.

Health Rep. 2019 Jul 17;30(7):3-12. doi: 10.25318/82-003-x201900700001-eng.

33.

Partial gonadal dysgenesis associated with a pathogenic variant of PBX1 transcription factor.

Kia F, Sarafoglou K, Mooganayakanakote Siddappa A, Roberts KD.

BMJ Case Rep. 2019 Jul 12;12(7). pii: e227986. doi: 10.1136/bcr-2018-227986.

PMID:
31302614
34.

Biologic Dose and Imaging Changes in Pediatric Brain Tumor Patients Receiving Spot Scanning Proton Therapy.

Roberts KW, Wan Chan Tseung HS, Eckel LJ, Harmsen WS, Beltran C, Laack NN.

Int J Radiat Oncol Biol Phys. 2019 Nov 1;105(3):664-673. doi: 10.1016/j.ijrobp.2019.06.2534. Epub 2019 Jul 10.

PMID:
31301328
35.

Body composition assessment and sarcopenia in patients with pancreatic cancer: a systematic review and meta-analysis.

Bundred J, Kamarajah SK, Roberts KJ.

HPB (Oxford). 2019 Jun 29. pii: S1365-182X(19)30568-4. doi: 10.1016/j.hpb.2019.05.018. [Epub ahead of print] Review.

PMID:
31266698
36.

Enhancing clinical concept extraction with contextual embeddings.

Si Y, Wang J, Xu H, Roberts K.

J Am Med Inform Assoc. 2019 Nov 1;26(11):1297-1304. doi: 10.1093/jamia/ocz096.

PMID:
31265066
37.

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.

Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A.

Nature. 2019 Jul;571(7764):284-288. doi: 10.1038/s41586-019-1355-4. Epub 2019 Jul 1.

PMID:
31263273
38.

Deep Patient Representation of Clinical Notes via Multi-Task Learning for Mortality Prediction.

Si Y, Roberts K.

AMIA Jt Summits Transl Sci Proc. 2019 May 6;2019:779-788. eCollection 2019.

39.

What are the implications of withholding total joint arthroplasty in the morbidly obese? A prospective, observational study.

Springer BD, Roberts KM, Bossi KL, Odum SM, Voellinger DC.

Bone Joint J. 2019 Jul;101-B(7_Supple_C):28-32. doi: 10.1302/0301-620X.101B7.BJJ-2018-1465.R1.

PMID:
31256642
40.

The Joint Counterterrorism Awareness Workshop Series (JCTAWS): Integrating disciplines for enhanced capabilities during a complex coordinated attack.

Shapiro GL, Armstrong JH, Roberts K, Gordon J, Smith ER, Afman J, Sasser SM.

J Emerg Manag. 2019 May/Jun;17(3):210-212. doi: 10.5055/jem.2019.0419.

PMID:
31245831
41.

The impact of HENRY on parenting and family lifestyle: Exploratory analysis of the mechanisms for change.

Bridge GL, Willis TA, Evans CEL, Roberts KPJ, Rudolf M.

Child Care Health Dev. 2019 Nov;45(6):850-860. doi: 10.1111/cch.12694. Epub 2019 Jul 24.

PMID:
31209923
42.

Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction.

Li J, Harnois LJ, Markos B, Roberts KM, Homoud SA, Liu J, Mirza S, Vines D.

Pharmaceutics. 2019 Jun 14;11(6). pii: E281. doi: 10.3390/pharmaceutics11060281.

43.

Cosmetic-Related Injuries Treated in US Emergency Departments: 2002 to 2016.

Vajda J, McAdams RJ, Roberts KJ, Zhu M, McKenzie LB.

Clin Pediatr (Phila). 2019 Dec;58(14):1493-1501. doi: 10.1177/0009922819850492. Epub 2019 Jun 16.

PMID:
31203655
44.

Radiotherapy Quality Assurance for the CHHiP Trial: Conventional Versus Hypofractionated High-Dose Intensity-Modulated Radiotherapy in Prostate Cancer.

Naismith O, Mayles H, Bidmead M, Clark CH, Gulliford S, Hassan S, Khoo V, Roberts K, South C, Hall E, Dearnaley D; CHHiP Investigators.

Clin Oncol (R Coll Radiol). 2019 Sep;31(9):611-620. doi: 10.1016/j.clon.2019.05.009. Epub 2019 Jun 11.

PMID:
31201110
45.

NCCN Guidelines Insights: B-Cell Lymphomas, Version 3.2019.

Zelenetz AD, Gordon LI, Abramson JS, Advani RH, Bartlett NL, Caimi PF, Chang JE, Chavez JC, Christian B, Fayad LE, Glenn MJ, Habermann TM, Lee Harris N, Hernandez-Ilizaliturri F, Kaminski MS, Kelsey CR, Khan N, Krivacic S, LaCasce AS, Mehta A, Nademanee A, Rabinovitch R, Reddy N, Reid E, Roberts KB, Smith SD, Snyder ED, Swinnen LJ, Vose JM, Dwyer MA, Sundar H.

J Natl Compr Canc Netw. 2019 Jun 1;17(6):650-661. doi: 10.6004/jnccn.2019.0029.

PMID:
31200358
46.

Response-adapted therapy for the treatment of children with newly diagnosed high risk Hodgkin lymphoma (AHOD0831): a report from the Children's Oncology Group.

Kelly KM, Cole PD, Pei Q, Bush R, Roberts KB, Hodgson DC, McCarten KM, Cho SY, Schwartz C.

Br J Haematol. 2019 Oct;187(1):39-48. doi: 10.1111/bjh.16014. Epub 2019 Jun 10.

PMID:
31180135
47.

PSC-RED and MNC-RED: Albumin-free and low-transferrin robust erythroid differentiation protocols to produce human enucleated red blood cells.

Olivier EN, Zhang S, Yan Z, Suzuka S, Roberts K, Wang K, Bouhassira EE.

Exp Hematol. 2019 Jul;75:31-52.e15. doi: 10.1016/j.exphem.2019.05.006. Epub 2019 Jun 6.

PMID:
31176681
48.

Reconsidering the relationship between fast-food outlets, area-level deprivation, diet quality and body mass index: an exploratory structural equation modelling approach.

Hobbs M, Green M, Roberts K, Griffiths C, McKenna J.

J Epidemiol Community Health. 2019 Sep;73(9):861-866. doi: 10.1136/jech-2018-211798. Epub 2019 Jun 6.

PMID:
31171581
49.

An Examination of the Association Between Relationship Mindfulness and Psychological and Relational Well-being in Committed Couples.

Kimmes JG, Jaurequi ME, Roberts K, Harris VW, Fincham FD.

J Marital Fam Ther. 2019 Jun 4. doi: 10.1111/jmft.12388. [Epub ahead of print]

PMID:
31162689
50.

AccessLab: Workshops to broaden access to scientific research.

Griffiths AGF, Modinou I, Heslop C, Brand C, Weatherill A, Baker K, Hughes AE, Lewis J, de Mora L, Mynott S, Roberts KE, Griffiths DJ.

PLoS Biol. 2019 May 28;17(5):e3000258. doi: 10.1371/journal.pbio.3000258. eCollection 2019 May.

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