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Items: 1 to 50 of 1101

1.

Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia.

Weber N, Jackson K, McWhinney B, Ungerer J, Kennedy G, Lipman J, Roberts JA.

J Infect Chemother. 2019 Mar 14. pii: S1341-321X(19)30047-9. doi: 10.1016/j.jiac.2019.02.014. [Epub ahead of print]

PMID:
30879981
2.

AUGMENTED RENAL CLEARANCE: A REAL PHENOMENON WITH AN UNCERTAIN CAUSE.

Baptista JP, Roberts JA, Udy AA.

Anaesth Crit Care Pain Med. 2019 Mar 8. pii: S2352-5568(19)30094-3. doi: 10.1016/j.accpm.2019.03.002. [Epub ahead of print] No abstract available.

PMID:
30857924
3.

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III.

Lipman J, Brett SJ, De Waele JJ, Cotta MO, Davis JS, Finfer S, Glass P, Knowles S, McGuinness S, Myburgh J, Paterson DL, Peake S, Rajbhandari D, Rhodes A, Roberts JA, Shirwadkar C, Starr T, Taylor C, Billot L, Dulhunty JM.

Crit Care Resusc. 2019 Mar;21(1):63-68.

PMID:
30857514
4.

Metastable brain waves.

Roberts JA, Gollo LL, Abeysuriya RG, Roberts G, Mitchell PB, Woolrich MW, Breakspear M.

Nat Commun. 2019 Mar 5;10(1):1056. doi: 10.1038/s41467-019-08999-0.

PMID:
30837462
5.

Defining optimal dosing of ciprofloxacin in patients with septic shock.

Roberts JA, Alobaid AS, Wallis SC, Perner A, Lipman J, Sjövall F.

J Antimicrob Chemother. 2019 Feb 26. pii: dkz069. doi: 10.1093/jac/dkz069. [Epub ahead of print]

PMID:
30809648
6.

Development of frontoparietal connectivity predicts longitudinal symptom changes in young people with autism spectrum disorder.

Lin HY, Perry A, Cocchi L, Roberts JA, Tseng WI, Breakspear M, Gau SS.

Transl Psychiatry. 2019 Feb 12;9(1):86. doi: 10.1038/s41398-019-0418-5.

7.

Re-evaluation of the ethylene-dependent and -independent pathways in the regulation of floral and organ abscission.

Meir S, Philosoph-Hadas S, Riov J, Tucker ML, Patterson SE, Roberts JA.

J Exp Bot. 2019 Mar 11;70(5):1461-1467. doi: 10.1093/jxb/erz038.

PMID:
30726930
8.

Heart Rate and Heart Rate Variability of Rhesus Macaques (Macaca mulatta) Affected by Left Ventricular Hypertrophy.

Ueda Y, Slabaugh TL, Walker AL, Ontiveros ES, Sosa PM, Reader R, Roberts JA, Stern JA.

Front Vet Sci. 2019 Jan 22;6:1. doi: 10.3389/fvets.2019.00001. eCollection 2019.

9.

Understanding drivers of antibiotic resistance genes in High Arctic soil ecosystems.

McCann CM, Christgen B, Roberts JA, Su JQ, Arnold KE, Gray ND, Zhu YG, Graham DW.

Environ Int. 2019 Apr;125:497-504. doi: 10.1016/j.envint.2019.01.034. Epub 2019 Jan 28.

10.

Intravenous fosfomycin for the treatment of multidrug-resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos G, Koulenti D, Parker SL, Roberts JA, Arvaniti K, Poulakou G.

Expert Rev Anti Infect Ther. 2019 Mar;17(3):201-210. doi: 10.1080/14787210.2019.1573669. Epub 2019 Feb 4.

PMID:
30668931
11.

Vancomycin Pharmacokinetics Throughout Life: Results from a Pooled Population Analysis and Evaluation of Current Dosing Recommendations.

Colin PJ, Allegaert K, Thomson AH, Touw DJ, Dolton M, de Hoog M, Roberts JA, Adane ED, Yamamoto M, Santos-Buelga D, Martín-Suarez A, Simon N, Taccone FS, Lo YL, Barcia E, Struys MMRF, Eleveld DJ.

Clin Pharmacokinet. 2019 Jan 17. doi: 10.1007/s40262-018-0727-5. [Epub ahead of print]

12.

Solid nanoparticles for oral antimicrobial drug delivery: a review.

Raza A, Sime FB, Cabot PJ, Maqbool F, Roberts JA, Falconer JR.

Drug Discov Today. 2019 Mar;24(3):858-866. doi: 10.1016/j.drudis.2019.01.004. Epub 2019 Jan 14. Review.

PMID:
30654055
13.

Personalized antibiotic dosing for the critically ill.

Roberts JA, Roger C, De Waele JJ.

Intensive Care Med. 2019 Jan 14. doi: 10.1007/s00134-019-05522-3. [Epub ahead of print] No abstract available.

PMID:
30637444
14.

Rotavirus is associated with decompensated diarrhea among young rhesus macaques (Macaca mulatta).

Wang KY, Christe KL, Yee J, Roberts JA, Ardeshir A.

Am J Primatol. 2019 Jan;81(1):e22948. doi: 10.1002/ajp.22948. Epub 2019 Jan 8.

PMID:
30620103
15.

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions.

Dhanani JA, Parker SL, Lipman J, Wallis SC, Cohen J, Fraser J, Barnett A, Chew M, Roberts JA.

J Pharm Anal. 2018 Dec;8(6):407-412. doi: 10.1016/j.jpha.2018.07.003. Epub 2018 Jul 6.

16.

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients.

Cheng V, Abdul-Aziz MH, Roberts JA, Shekar K.

Expert Opin Drug Metab Toxicol. 2019 Feb;15(2):103-112. doi: 10.1080/17425255.2019.1563596. Epub 2019 Jan 3. Review.

PMID:
30582435
17.

In vitro removal of anti-infective agents by a novel cytokine adsorbent system.

König C, Röhr AC, Frey OR, Brinkmann A, Roberts JA, Wichmann D, Braune S, Kluge S, Nierhaus A.

Int J Artif Organs. 2019 Feb;42(2):57-64. doi: 10.1177/0391398818812601. Epub 2018 Dec 13.

PMID:
30545255
18.

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: A systematic review.

Heffernan AJ, Sime FB, Lipman J, Dhanani J, Andrews K, Ellwood D, Grimwood K, Roberts JA.

Int J Antimicrob Agents. 2019 Mar;53(3):234-245. doi: 10.1016/j.ijantimicag.2018.11.011. Epub 2018 Nov 23. Review.

PMID:
30472292
19.

Diazepam Toxicity Presenting as a Dementia Disorder.

Kurlawala Z, Roberts JA, McMillan JD, Friedland RP.

J Alzheimers Dis. 2018;66(3):935-938. doi: 10.3233/JAD-180745.

PMID:
30400100
20.

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models.

Dhaese SAM, Farkas A, Colin P, Lipman J, Stove V, Verstraete AG, Roberts JA, De Waele JJ.

J Antimicrob Chemother. 2019 Feb 1;74(2):432-441. doi: 10.1093/jac/dky434.

PMID:
30376103
21.

Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics.

Jamal JA, Roger C, Roberts JA.

Anaesth Crit Care Pain Med. 2018 Dec;37(6):515-517. doi: 10.1016/j.accpm.2018.10.006. Epub 2018 Oct 22. No abstract available.

PMID:
30359771
22.

Pharmacokinetics of Ceftolozane-Tazobactam during Prolonged Intermittent Renal Replacement Therapy.

Rawlins M, Cheng V, Raby E, Dyer J, Regli A, Ingram P, McWhinney BC, Ungerer JPJ, Roberts JA.

Chemotherapy. 2018;63(4):203-206. doi: 10.1159/000493196. Epub 2018 Oct 10.

PMID:
30304718
23.

How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients.

Heffernan AJ, Sime FB, Taccone FS, Roberts JA.

Curr Opin Infect Dis. 2018 Dec;31(6):555-565. doi: 10.1097/QCO.0000000000000494.

PMID:
30299354
24.

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis.

Abraham J, Sinnollareddy MG, Roberts MS, Williams P, Peake SL, Lipman J, Roberts JA.

Int J Antimicrob Agents. 2019 Feb;53(2):137-142. doi: 10.1016/j.ijantimicag.2018.09.021. Epub 2018 Oct 5.

PMID:
30296581
25.

Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures.

Wong G, Briscoe S, McWhinney B, Ally M, Ungerer J, Lipman J, Roberts JA.

J Antimicrob Chemother. 2018 Nov 1;73(11):3087-3094. doi: 10.1093/jac/dky314.

PMID:
30137377
26.

A Robust Statistical Approach to Analyse Population Pharmacokinetic Data in Critically Ill Patients Receiving Renal Replacement Therapy.

Paul SK, Roberts JA, Lipman J, Deans R, Samanta M.

Clin Pharmacokinet. 2019 Feb;58(2):263-270. doi: 10.1007/s40262-018-0690-1.

PMID:
30094712
27.

Ex Vivo Characterization of Effects of Renal Replacement Therapy Modalities and Settings on Pharmacokinetics of Meropenem and Vaborbactam.

Sime FB, Pandey S, Karamujic N, Parker S, Alexander E, Loutit J, Durso S, Griffith D, Lipman J, Wallis SC, Roberts JA.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e01306-18. doi: 10.1128/AAC.01306-18. Print 2018 Oct.

28.

Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes.

Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK; Type 1 Diabetes TrialNet Study Group.

Diabetes Care. 2019 Feb;42(2):192-199. doi: 10.2337/dc18-0288. Epub 2018 Jul 30.

PMID:
30061316
29.

Fragility and volatility of structural hubs in the human connectome.

Gollo LL, Roberts JA, Cropley VL, Di Biase MA, Pantelis C, Zalesky A, Breakspear M.

Nat Neurosci. 2018 Aug;21(8):1107-1116. doi: 10.1038/s41593-018-0188-z. Epub 2018 Jul 23.

PMID:
30038275
30.

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminaemia receiving continuous venovenous haemodiafiltration.

Sime FB, Stuart J, Butler J, Starr T, Wallis SC, Pandey S, Lipman J, Roberts JA.

Int J Antimicrob Agents. 2018 Oct;52(4):506-509. doi: 10.1016/j.ijantimicag.2018.07.008. Epub 2018 Jul 19.

PMID:
30031203
31.

Gut-derived serotonin contributes to bone deficits in colitis.

Lavoie B, Roberts JA, Haag MM, Spohn SN, Margolis KG, Sharkey KA, Lian JB, Mawe GM.

Pharmacol Res. 2019 Feb;140:75-84. doi: 10.1016/j.phrs.2018.07.018. Epub 2018 Jul 17.

PMID:
30030171
32.

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models.

Dhanani JA, Cohen J, Parker SL, Chan HK, Tang P, Ahern BJ, Khan A, Bhatt M, Goodman S, Diab S, Chaudhary J, Lipman J, Wallis SC, Barnett A, Chew M, Fraser JF, Roberts JA.

Intensive Care Med Exp. 2018 Jul 11;6(1):17. doi: 10.1186/s40635-018-0180-7.

33.

β-Lactam Dosage Regimens in Septic Patients with Augmented Renal Clearance.

Jacobs A, Taccone FS, Roberts JA, Jacobs F, Cotton F, Wolff F, Creteur J, Vincent JL, Hites M.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e02534-17. doi: 10.1128/AAC.02534-17. Print 2018 Sep.

34.

Young Children's Structure Production: A Revision of the Index of Productive Syntax.

Altenberg EP, Roberts JA, Scarborough HS.

Lang Speech Hear Serv Sch. 2018 Oct 24;49(4):995-1008. doi: 10.1044/2018_LSHSS-17-0092.

PMID:
29978201
35.

Pharmacodynamic Target Attainment for Cefepime, Meropenem, and Piperacillin-Tazobactam Using a Pharmacokinetic/Pharmacodynamic-Based Dosing Calculator in Critically Ill Patients.

Heil EL, Nicolau DP, Farkas A, Roberts JA, Thom KA.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e01008-18. doi: 10.1128/AAC.01008-18. Print 2018 Sep.

36.

Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis.

Tsai D, Stewart PC, Hewagama S, Krishnaswamy S, Wallis SC, Lipman J, Roberts JA.

Anaesth Intensive Care. 2018 Jul;46(4):374-380.

PMID:
29966110
37.

The authors reply.

Rhodes NJ, Liu J, Lipman J, Roberts JA.

Crit Care Med. 2018 Jul;46(7):e725-e726. doi: 10.1097/CCM.0000000000003164. No abstract available.

PMID:
29912126
38.

Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury.

Parker SL, Saxena M, Gowardman J, Lipman J, Myburgh J, Roberts JA.

J Crit Care. 2018 Oct;47:15-20. doi: 10.1016/j.jcrc.2018.05.016. Epub 2018 May 30.

PMID:
29883885
39.

New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimization rapid microbiological methods.

Abdul-Aziz MH, Driver E, Lipman J, Roberts JA.

Expert Opin Drug Metab Toxicol. 2018 Jul;14(7):693-708. doi: 10.1080/17425255.2018.1484452. Epub 2018 Jun 14. Review.

PMID:
29865877
40.

Synaptic assays: using biophysical models to infer neuronal dysfunction from non-invasive EEG.

Roberts JA, Breakspear M.

Brain. 2018 Jun 1;141(6):1583. doi: 10.1093/brain/awy136. No abstract available.

PMID:
29800477
41.

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation.

Cheng V, Abdul-Aziz MH, Roberts JA, Shekar K.

J Thorac Dis. 2018 Mar;10(Suppl 5):S629-S641. doi: 10.21037/jtd.2017.09.154. Review.

42.

Piperacillin Population Pharmacokinetics in Critically Ill Adults During Sustained Low-Efficiency Dialysis.

Kanji S, Roberts JA, Xie J, Alobaid A, Zelenitsky S, Hiremath S, Zhang G, Watpool I, Porteous R, Patel R.

Ann Pharmacother. 2018 Oct;52(10):965-973. doi: 10.1177/1060028018773771. Epub 2018 May 7.

PMID:
29730948
43.

Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients.

Bukkems LH, Roger C, Hodiamont CJ, Lefrant JY, Juffermans NP, Roberts JA, van Hest RM.

Int J Antimicrob Agents. 2018 Aug;52(2):218-225. doi: 10.1016/j.ijantimicag.2018.04.016. Epub 2018 Apr 26.

PMID:
29704547
44.

Population Pharmacokinetics of Periarticular Ketorolac in Adult Patients Undergoing Total Hip or Total Knee Replacement Surgery.

Gurunathan U, Parker SL, Maguire R, Ramdath D, Bijoor M, Wallis SC, Roberts JA.

Anesth Analg. 2018 Apr 23. doi: 10.1213/ANE.0000000000003377. [Epub ahead of print]

PMID:
29697507
45.

Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients.

Maseda E, Grau S, Luque S, Castillo-Mafla MP, Suárez-de-la-Rica A, Montero-Feijoo A, Salgado P, Gimenez MJ, García-Bernedo CA, Gilsanz F, Roberts JA.

Crit Care. 2018 Apr 15;22(1):94. doi: 10.1186/s13054-018-2019-8.

46.

Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients.

Sime FB, Stuart J, Butler J, Starr T, Wallis SC, Pandey S, Lipman J, Roberts JA.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00242-18. doi: 10.1128/AAC.00242-18. Print 2018 Jun.

47.

Individualising Therapy to Minimize Bacterial Multidrug Resistance.

Heffernan AJ, Sime FB, Lipman J, Roberts JA.

Drugs. 2018 Apr;78(6):621-641. doi: 10.1007/s40265-018-0891-9. Review.

PMID:
29569104
48.

Valganciclovir Pharmacokinetics in Patients Receiving Oral Prophylaxis Following Kidney Transplantation and Model-Based Predictions of Optimal Dosing Regimens.

Tängdén T, Cojutti PG, Roberts JA, Pea F.

Clin Pharmacokinet. 2018 Nov;57(11):1399-1405. doi: 10.1007/s40262-018-0638-5.

PMID:
29546589
49.

Clinical Applications of Stochastic Dynamic Models of the Brain, Part II: A Review.

Roberts JA, Friston KJ, Breakspear M.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Apr;2(3):225-234. doi: 10.1016/j.bpsc.2016.12.009. Epub 2017 Feb 10. Review.

PMID:
29528294
50.

Clinical Applications of Stochastic Dynamic Models of the Brain, Part I: A Primer.

Roberts JA, Friston KJ, Breakspear M.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Apr;2(3):216-224. doi: 10.1016/j.bpsc.2017.01.010. Epub 2017 Feb 7. Review.

PMID:
29528293

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