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Items: 1 to 50 of 1280

1.

Trial management: we need a cadre of high-class triallists to deliver the answers that patients need.

Beaumont D, Arribas M, Frimley L, Balogun E, Roberts I, Shakur-Still H.

Trials. 2019 Jun 13;20(1):354. doi: 10.1186/s13063-019-3451-z.

PMID:
31196151
2.

Death and Rebirth of the Autopsy.

Roberts I.

Med Leg J. 2019 Jun 10:25817219844173. doi: 10.1177/0025817219844173. [Epub ahead of print] No abstract available.

PMID:
31179879
3.

Odd combinations-coexistence of anti-glomerular basement membrane disease and Sjögren's syndrome.

Ahmed A, Ahmad N, Dibbur V, Price E, Roberts ISD.

Rheumatology (Oxford). 2019 Jun 6. pii: kez208. doi: 10.1093/rheumatology/kez208. [Epub ahead of print] No abstract available.

PMID:
31170292
4.

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan.

Mahmood A, Roberts I, Shakur-Still H.

Version 2. Wellcome Open Res. 2019 Jan 8 [revised 2019 Jan 1];3:99. doi: 10.12688/wellcomeopenres.14731.2. eCollection 2018.

5.

Prognostic model for traumatic death due to bleeding: cross-sectional international study.

Ageron FX, Gayet-Ageron A, Steyerberg E, Bouzat P, Roberts I.

BMJ Open. 2019 May 28;9(5):e026823. doi: 10.1136/bmjopen-2018-026823.

6.

Long term outcomes in monoclonal gammopathy of renal significance.

Khera A, Panitsas F, Djebbari F, Kimberger K, Stern S, Quinn J, Rabin N, Kothari J, Alchi B, Haynes R, Winearls C, Roberts I, Ramasamy K.

Br J Haematol. 2019 May 29. doi: 10.1111/bjh.15987. [Epub ahead of print]

PMID:
31141168
7.

Tranexamic acid for post-partum haemorrhage: What, who and when.

Brenner A, Ker K, Shakur-Still H, Roberts I.

Best Pract Res Clin Obstet Gynaecol. 2019 Apr 30. pii: S1521-6934(19)30041-0. doi: 10.1016/j.bpobgyn.2019.04.005. [Epub ahead of print] Review.

PMID:
31128974
8.

Germline selection shapes human mitochondrial DNA diversity.

Wei W, Tuna S, Keogh MJ, Smith KR, Aitman TJ, Beales PL, Bennett DL, Gale DP, Bitner-Glindzicz MAK, Black GC, Brennan P, Elliott P, Flinter FA, Floto RA, Houlden H, Irving M, Koziell A, Maher ER, Markus HS, Morrell NW, Newman WG, Roberts I, Sayer JA, Smith KGC, Taylor JC, Watkins H, Webster AR, Wilkie AOM, Williamson C; NIHR BioResource–Rare Diseases; 100,000 Genomes Project–Rare Diseases Pilot, Ashford S, Penkett CJ, Stirrups KE, Rendon A, Ouwehand WH, Bradley JR, Raymond FL, Caulfield M, Turro E, Chinnery PF.

Science. 2019 May 24;364(6442). pii: eaau6520. doi: 10.1126/science.aau6520. Epub 2019 May 23.

PMID:
31123110
9.

Affect and Decision Making: Insights and Predictions from Computational Models.

Roberts ID, Hutcherson CA.

Trends Cogn Sci. 2019 May 16. pii: S1364-6613(19)30097-X. doi: 10.1016/j.tics.2019.04.005. [Epub ahead of print] Review.

PMID:
31104816
10.

Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage.

Cornelissen L, Woodd S, Shakur-Still H, Fawole B, Noor S, Etuk S, Akintan AL, Chaudhri R, Roberts I.

Int J Gynaecol Obstet. 2019 May 13. doi: 10.1002/ijgo.12860. [Epub ahead of print]

PMID:
31081140
11.

Fibroblast migration correlates with matrix softness. A study in knob-hole engineered fibrin.

Leon-Valdivieso CY, Wedgwood J, Lallana E, Donno R, Roberts I, Ghibaudi M, Tirella A, Tirelli N.

APL Bioeng. 2018 Jul 17;2(3):036102. doi: 10.1063/1.5022841. eCollection 2018 Sep.

12.

Tranexamic acid through intravenous, intramuscular and oral routes: an individual participant data meta-analysis of pharmacokinetic studies in healthy volunteers.

Grassin-Delyle S, Semeraro M, Foissac F, Bouazza N, Shakur-Still H, Roberts I, Treluyer JM, Urien S.

Fundam Clin Pharmacol. 2019 Apr 23. doi: 10.1111/fcp.12474. [Epub ahead of print]

PMID:
31013357
13.

Impaired cellular and humoral immunity is a feature of Diamond-Blackfan anaemia; experience of 107 unselected cases in the United Kingdom.

Iskander D, Roberts I, Rees C, Szydlo R, Alikian M, Neale M, Harrington Y, Kelleher P, Karadimitris A, de la Fuente J.

Br J Haematol. 2019 Apr 13. doi: 10.1111/bjh.15915. [Epub ahead of print]

PMID:
30980390
14.

A Novel Deletion in the RPL5 Gene in a Lebanese Child With Diamond Blackfan Anemia Unresponsive to Steroid Treatment.

Farah RA, Kamel L, Roy N, Proven M, Wray K, Roberts I, Wlodarski MW.

J Pediatr Hematol Oncol. 2019 Mar 29. doi: 10.1097/MPH.0000000000001435. [Epub ahead of print]

PMID:
30933022
15.

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.

Hua P, Kronsteiner B, van der Garde M, Ashley N, Hernandez D, Tarunina M, Hook L, Choo Y, Roberts I, Mead A, Watt SM.

Sci Rep. 2019 Mar 28;9(1):5300. doi: 10.1038/s41598-019-41803-z.

16.

Super-Resolution Fluorescence Microscopy Study of the Production of K1 Capsules by Escherichia coli: Evidence for the Differential Distribution of the Capsule at the Poles and the Equator of the Cell.

Phanphak S, Georgiades P, Li R, King J, Roberts IS, Waigh TA.

Langmuir. 2019 Apr 23;35(16):5635-5646. doi: 10.1021/acs.langmuir.8b04122. Epub 2019 Apr 9.

17.

Oxytocin and the altruistic 'Goldilocks zone'.

Roberts ID, Teoh YY, Hutcherson CA.

Nat Neurosci. 2019 Apr;22(4):510-512. doi: 10.1038/s41593-019-0362-y. No abstract available.

PMID:
30911180
18.

Subtilase activity and gene expression during germination and seedling growth in barley.

Galotta MF, Pugliese P, Gutiérrez-Boem FH, Veliz CG, Criado MV, Caputo C, Echeverria M, Roberts IN.

Plant Physiol Biochem. 2019 Jun;139:197-206. doi: 10.1016/j.plaphy.2019.03.021. Epub 2019 Mar 16.

PMID:
30908971
19.

Adenovirus 5 recovery using nanofiber ion-exchange adsorbents.

Turnbull J, Wright B, Green NK, Tarrant R, Roberts I, Hardick O, Bracewell DG.

Biotechnol Bioeng. 2019 Jul;116(7):1698-1709. doi: 10.1002/bit.26972. Epub 2019 Mar 28.

PMID:
30883678
20.

Erratum.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Maria Asunis A, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez E, Haider SA, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2019 Mar 16. pii: gfz001. doi: 10.1093/ndt/gfz001. [Epub ahead of print] No abstract available.

PMID:
30879042
21.

Acetaminophen influences social and economic trust.

Roberts ID, Krajbich I, Way BM.

Sci Rep. 2019 Mar 11;9(1):4060. doi: 10.1038/s41598-019-40093-9.

22.

Mice With a Brd4 Mutation Represent a New Model of Nephrocalcinosis.

Gorvin CM, Loh NY, Stechman MJ, Falcone S, Hannan FM, Ahmad BN, Piret SE, Reed AA, Jeyabalan J, Leo P, Marshall M, Sethi S, Bass P, Roberts I, Sanderson J, Wells S, Hough TA, Bentley L, Christie PT, Simon MM, Mallon AM, Schulz H, Cox RD, Brown MA, Huebner N, Brown SD, Thakker RV.

J Bone Miner Res. 2019 Mar 4. doi: 10.1002/jbmr.3695. [Epub ahead of print]

PMID:
30830987
23.

Reply to Maxine G. Tran, Ravi Barod, and Axel Bex's Letter to the Editor re: Philip S. Macklin, Mark E. Sullivan, Charles R. Tapping, et al. Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre. Eur Urol 2019;75:861-7.

Macklin PS, Sullivan ME, Tapping CR, Webster GM, Roberts ISD, Verrill CL, Browning L.

Eur Urol. 2019 Jun;75(6):e177-e178. doi: 10.1016/j.eururo.2019.02.029. Epub 2019 Mar 1. No abstract available.

PMID:
30827695
24.

Fabrication and characterisation of 3D printed MWCNT composite porous scaffolds for bone regeneration.

Huang B, Vyas C, Roberts I, Poutrel QA, Chiang WH, Blaker JJ, Huang Z, Bártolo P.

Mater Sci Eng C Mater Biol Appl. 2019 May;98:266-278. doi: 10.1016/j.msec.2018.12.100. Epub 2018 Dec 28.

PMID:
30813027
25.

Microrheology and Spatial Heterogeneity of Staphylococcus aureus Biofilms Modulated by Hydrodynamic Shear and Biofilm-Degrading Enzymes.

Hart JW, Waigh TA, Lu JR, Roberts IS.

Langmuir. 2019 Mar 5;35(9):3553-3561. doi: 10.1021/acs.langmuir.8b04252. Epub 2019 Feb 15.

PMID:
30707032
26.

Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.

Agraz-Doblas A, Bueno C, Bashford-Rogers R, Roy A, Schneider P, Bardini M, Ballerini P, Cazzaniga G, Moreno T, Revilla C, Gut M, Valsecchi MG, Roberts I, Pieters R, De Lorenzo P, Varela I, Menendez P, Stam RW.

Haematologica. 2019 Jun;104(6):1176-1188. doi: 10.3324/haematol.2018.206375. Epub 2019 Jan 24.

27.

Effectiveness and cost-effectiveness of a Yoga-based Cardiac Rehabilitation (Yoga-CaRe) program following acute myocardial infarction: Study rationale and design of a multi-center randomized controlled trial.

Chandrasekaran AM, Kinra S, Ajay VS, Chattopadhyay K, Singh K, Singh K, Praveen PA, Soni D, Devarajan R, Kondal D, Manchanda SC, Hughes AD, Chaturvedi N, Roberts I, Pocock S, Ebrahim S, Reddy KS, Tandon N, Prabhakaran D; Yoga-CaRe Trial Team.

Int J Cardiol. 2019 Apr 1;280:14-18. doi: 10.1016/j.ijcard.2019.01.012. Epub 2019 Jan 7.

PMID:
30661847
28.

The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial.

Nishijima DK, Kuppermann N, Roberts I, VanBuren JM, Tancredi DJ.

Ann Emerg Med. 2019 Jan 12. pii: S0196-0644(18)31467-7. doi: 10.1016/j.annemergmed.2018.11.018. [Epub ahead of print]

PMID:
30642657
29.

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial.

Ker K, Roberts I, Chaudhri R, Fawole B, Beaumont D, Balogun E, Prowse D, Pepple T, Javaid K, Kayani A, Arulkumaran S, Bates I, Shakur-Still H; WOMAN-2 trial collaborators.

Trials. 2018 Dec 29;19(1):712. doi: 10.1186/s13063-018-3081-x.

30.

Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre.

Macklin PS, Sullivan ME, Tapping CR, Cranston DW, Webster GM, Roberts ISD, Verrill CL, Browning L.

Eur Urol. 2019 May;75(5):861-867. doi: 10.1016/j.eururo.2018.12.011. Epub 2018 Dec 24.

PMID:
30591353
31.

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies.

Picetti R, Shakur-Still H, Medcalf RL, Standing JF, Roberts I.

Blood Coagul Fibrinolysis. 2019 Jan;30(1):1-10. doi: 10.1097/MBC.0000000000000789.

32.

Reproducibility of the Oxford classification of immunoglobulin A nephropathy, impact of biopsy scoring on treatment allocation and clinical relevance of disagreements: evidence from the VALidation of IGA study cohort.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Asunis AM, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez EM, Asma Haider S, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2018 Dec 15. doi: 10.1093/ndt/gfy337. [Epub ahead of print]

PMID:
30561721
33.

Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study.

Coats TJ, Fragoso-Iñiguez M, Roberts I.

Emerg Med J. 2019 Feb;36(2):78-81. doi: 10.1136/emermed-2018-207693. Epub 2018 Dec 8.

PMID:
30530744
34.

Diverse Lineages of Candida albicans Live on Old Oaks.

Bensasson D, Dicks J, Ludwig JM, Bond CJ, Elliston A, Roberts IN, James SA.

Genetics. 2019 Jan;211(1):277-288. doi: 10.1534/genetics.118.301482. Epub 2018 Nov 21.

35.

Quenched Stochastic Optical Reconstruction Microscopy (qSTORM) with Graphene Oxide.

Li R, Georgiades P, Cox H, Phanphak S, Roberts IS, Waigh TA, Lu JR.

Sci Rep. 2018 Nov 16;8(1):16928. doi: 10.1038/s41598-018-35297-4.

36.

Is there long-term value of pathology scoring in immunoglobulin A nephropathy? A validation study of the Oxford Classification for IgA Nephropathy (VALIGA) update.

Coppo R, D'Arrigo G, Tripepi G, Russo ML, Roberts ISD, Bellur S, Cattran D, Cook TH, Feehally J, Tesar V, Maixnerova D, Peruzzi L, Amore A, Lundberg S, Di Palma AM, Gesualdo L, Emma F, Rollino C, Praga M, Biancone L, Pani A, Feriozzi S, Polci R, Barratt J, Del Vecchio L, Locatelli F, Pierucci A, Caliskan Y, Perkowska-Ptasinska A, Durlik M, Moggia E, Ballarin JC, Wetzels JFM, Goumenos D, Papasotiriou M, Galesic K, Toric L, Papagianni A, Stangou M, Benozzi L, Cusinato S, Berg U, Topaloglu R, Maggio M, Ots-Rosenberg M, D'Amico M, Geddes C, Balafa O, Quaglia M, Cravero R, Lino Cirami C, Fellstrom B, Floege J, Egido J, Mallamaci F, Zoccali C.

Nephrol Dial Transplant. 2018 Nov 9. doi: 10.1093/ndt/gfy302. [Epub ahead of print]

PMID:
30418652
37.

Conceptualizing multiple drug use in patients with comorbidity and multimorbidity: proposal for standard definitions beyond the term polypharmacy.

Kadam UT, Roberts I, White S, Bednall R, Khunti K, Nilsson PM, Lawson CA.

J Clin Epidemiol. 2019 Feb;106:98-107. doi: 10.1016/j.jclinepi.2018.10.014. Epub 2018 Oct 29.

PMID:
30385327
38.

Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial.

Nishijima DK, VanBuren J, Hewes HA, Myers SR, Stanley RM, Adelson PD, Barnhard SE, Bobinski M, Ghetti S, Holmes JF, Roberts I, Schalick WO 3rd, Tran NK, Tzimenatos LS, Michael Dean J, Kuppermann N; TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network.

Trials. 2018 Oct 30;19(1):593. doi: 10.1186/s13063-018-2974-z.

39.

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial.

Shakur-Still H, Roberts I, Fawole B, Kuti M, Olayemi OO, Bello A, Huque S, Ogunbode O, Kotila T, Aimakhu C, Okunade OA, Olutogun T, Adetayo CO, Dallaku K, Mansmann U, Hunt BJ, Pepple T, Balogun E.

Wellcome Open Res. 2018 Aug 15;3:100. doi: 10.12688/wellcomeopenres.14722.1. eCollection 2018.

40.

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.

Roberts I, Belli A, Brenner A, Chaudhri R, Fawole B, Harris T, Jooma R, Mahmood A, Shokunbi T, Shakur H; CRASH-3 trial collaborators.

Version 2. Wellcome Open Res. 2018 Sep 26 [revised 2018 Jan 1];3:86. doi: 10.12688/wellcomeopenres.14700.2. eCollection 2018.

41.

Relationship between renal CD68+ infiltrates and the Oxford Classification of IgA nephropathy.

Soares MF, Genitsch V, Chakera A, Smith A, MacEwen C, Bellur SS, Alham NK, Roberts ISD.

Histopathology. 2019 Mar;74(4):629-637. doi: 10.1111/his.13768. Epub 2019 Jan 15.

PMID:
30303541
42.

Outcome measures in clinical trials of treatments for acute severe haemorrhage.

Brenner A, Arribas M, Cuzick J, Jairath V, Stanworth S, Ker K, Shakur-Still H, Roberts I.

Trials. 2018 Oct 1;19(1):533. doi: 10.1186/s13063-018-2900-4.

43.

Women's work in UK clinical trials is undervalued.

Roberts I.

Lancet. 2018 Sep 1;392(10149):732. doi: 10.1016/S0140-6736(18)31540-X. No abstract available.

PMID:
30191824
44.

Histologic Classification of IgA Nephropathy: Past, Present, and Future.

Soares MFS, Roberts ISD.

Semin Nephrol. 2018 Sep;38(5):477-484. doi: 10.1016/j.semnephrol.2018.05.017. Review.

PMID:
30177019
45.

Understanding and predicting disease relationships through similarity fusion.

Oerton E, Roberts I, Lewis PSH, Guilliams T, Bender A.

Bioinformatics. 2019 Apr 1;35(7):1213-1220. doi: 10.1093/bioinformatics/bty754.

46.

Finding Better Ways to Prevent Postpartum Hemorrhage.

Shakur-Still H, Roberts I.

N Engl J Med. 2018 Aug 23;379(8):790-792. doi: 10.1056/NEJMe1808500. No abstract available.

47.

Colloids versus crystalloids for fluid resuscitation in critically ill people.

Lewis SR, Pritchard MW, Evans DJ, Butler AR, Alderson P, Smith AF, Roberts I.

Cochrane Database Syst Rev. 2018 Aug 3;8:CD000567. doi: 10.1002/14651858.CD000567.pub7.

PMID:
30073665
48.

Should hydroxyethyl starch be banned? - Authors' reply.

Roberts I, Shakur H, Bellomo R, Bion J, Finfer S, Hunt B, Myburgh J, Perner A, Reinhart K.

Lancet. 2018 Jul 14;392(10142):119. doi: 10.1016/S0140-6736(18)31179-6. No abstract available.

PMID:
30017130
49.

Release of cell wall phenolic esters during hydrothermal pretreatment of rice husk and rice straw.

Wu J, Collins SRA, Elliston A, Wellner N, Dicks J, Roberts IN, Waldron KW.

Biotechnol Biofuels. 2018 Jun 11;11:162. doi: 10.1186/s13068-018-1157-1. eCollection 2018.

50.

Guidelines for the investigation and management of Transient Leukaemia of Down Syndrome.

Tunstall O, Bhatnagar N, James B, Norton A, O'Marcaigh AS, Watts T, Greenough A, Vyas P, Roberts I, Wright M; British Society for Haematology.

Br J Haematol. 2018 Jul;182(2):200-211. doi: 10.1111/bjh.15390. Epub 2018 Jun 19. No abstract available.

PMID:
29916557

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