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Items: 1 to 50 of 1300

1.

Germline variants in predisposition genes in children with Down syndrome and acute lymphoblastic leukemia.

Winer P, Muskens IS, Walsh KM, Vora A, Moorman AV, Wiemels JL, Roberts I, Roy A, de Smith AJ.

Blood Adv. 2020 Feb 25;4(4):672-675. doi: 10.1182/bloodadvances.2019001216. No abstract available.

PMID:
32084258
2.

Membrane potentials, oxidative stress and the dispersal response of bacterial biofilms to 405 nm light.

Blee JA, Roberts IS, Waigh TA.

Phys Biol. 2020 Feb 12. doi: 10.1088/1478-3975/ab759a. [Epub ahead of print]

PMID:
32050190
3.

Spatial propagation of electrical signals in circular biofilms: A combined experimental and agent-based fire-diffuse-fire study.

Blee JA, Roberts IS, Waigh TA.

Phys Rev E. 2019 Nov;100(5-1):052401. doi: 10.1103/PhysRevE.100.052401.

PMID:
31870031
4.

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan.

Mahmood A, Roberts I, Shakur-Still H.

Version 3. Wellcome Open Res. 2019 Nov 27 [revised 2019 Jan 1];3:99. doi: 10.12688/wellcomeopenres.14731.3. eCollection 2018.

5.

Global sea-surface iodide observations, 1967-2018.

Chance RJ, Tinel L, Sherwen T, Baker AR, Bell T, Brindle J, Campos MLAM, Croot P, Ducklow H, Peng H, Hopkins F, Hoogakker B, Hughes C, Jickells TD, Loades D, Macaya DAR, Mahajan AS, Malin G, Phillips D, Roberts I, Roy R, Sarkar A, Sinha AK, Song X, Winkelbauer H, Wuttig K, Yang M, Peng Z, Carpenter LJ.

Sci Data. 2019 Nov 26;6(1):286. doi: 10.1038/s41597-019-0288-y.

6.

Fibrin Matrices as (Injectable) Biomaterials: Formation, Clinical Use, and Molecular Engineering.

Roberts IV, Bukhary D, Valdivieso CYL, Tirelli N.

Macromol Biosci. 2020 Jan;20(1):e1900283. doi: 10.1002/mabi.201900283. Epub 2019 Nov 18. Review.

PMID:
31769933
7.
8.

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.

Hua P, Roy N, de la Fuente J, Wang G, Thongjuea S, Clark K, Roy A, Psaila B, Ashley N, Harrington Y, Nerlov C, Watt SM, Roberts I, Davies JOJ.

Blood. 2019 Dec 5;134(23):2111-2115. doi: 10.1182/blood.2019002301. No abstract available.

PMID:
31697810
9.

Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event.

Tillin T, Tuson C, Sowa B, Chattopadhyay K, Sattar N, Welsh P, Roberts I, Ebrahim S, Kinra S, Hughes A, Chaturvedi N.

BMJ Open. 2019 Nov 3;9(11):e030119. doi: 10.1136/bmjopen-2019-030119.

10.

Decoding human fetal liver haematopoiesis.

Popescu DM, Botting RA, Stephenson E, Green K, Webb S, Jardine L, Calderbank EF, Polanski K, Goh I, Efremova M, Acres M, Maunder D, Vegh P, Gitton Y, Park JE, Vento-Tormo R, Miao Z, Dixon D, Rowell R, McDonald D, Fletcher J, Poyner E, Reynolds G, Mather M, Moldovan C, Mamanova L, Greig F, Young MD, Meyer KB, Lisgo S, Bacardit J, Fuller A, Millar B, Innes B, Lindsay S, Stubbington MJT, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Filby A, Carey P, Villani AC, Roy A, Regev A, Chédotal A, Roberts I, Göttgens B, Behjati S, Laurenti E, Teichmann SA, Haniffa M.

Nature. 2019 Oct;574(7778):365-371. doi: 10.1038/s41586-019-1652-y. Epub 2019 Oct 9.

PMID:
31597962
11.

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK.

J Exp Med. 2019 Dec 2;216(12):2714-2723. doi: 10.1084/jem.20180610. Epub 2019 Oct 3.

12.

Short-term outcome of surgical arthrodiastasis of the ankle with Ilizarov frame in a cohort of children and young people with juvenile idiopathic arthritis.

Cleary G, Pain C, McCann L, Mahmood K, Brookes-Fazakerley S, Robinson S, Walton R, Highcock A, Landes C, Barnes N, Roberts I, James L.

Rheumatol Adv Pract. 2019 Aug 14;3(2):rkz031. doi: 10.1093/rap/rkz031. eCollection 2019.

13.

Tumour seeding of the renal tumour biopsy tract - a histologically under-recognised feature?

Macklin PS, Verrill CL, Roberts IS, Colling R, Sullivan ME, Webster GM, Cranston DW, Tapping CR, Browning L.

Histopathology. 2019 Sep 26. doi: 10.1111/his.14004. [Epub ahead of print]

PMID:
31557341
14.

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH.

Cancer Cell. 2019 Sep 16;36(3):340. doi: 10.1016/j.ccell.2019.08.014. No abstract available.

PMID:
31526763
15.

Autoantigens PLA2R and THSD7A in membranous nephropathy share a common epitope motif in the N-terminal domain.

Fresquet M, Rhoden SJ, Jowitt TA, McKenzie EA, Roberts I, Lennon R, Brenchley PE.

J Autoimmun. 2020 Jan;106:102308. doi: 10.1016/j.jaut.2019.102308. Epub 2019 Aug 5.

16.

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.

O'Byrne S, Elliott N, Rice S, Buck G, Fordham N, Garnett C, Godfrey L, Crump NT, Wright G, Inglott S, Hua P, Psaila B, Povinelli B, Knapp DJHF, Agraz-Doblas A, Bueno C, Varela I, Bennett P, Koohy H, Watt SM, Karadimitris A, Mead AJ, Ancliff P, Vyas P, Menendez P, Milne TA, Roberts I, Roy A.

Blood. 2019 Sep 26;134(13):1059-1071. doi: 10.1182/blood.2019001289. Epub 2019 Aug 5.

PMID:
31383639
17.

Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.

Brenner A, Afolabi A, Ahmad SM, Arribas M, Chaudhri R, Coats T, Cuzick J, Gilmore I, Hawkey C, Jairath V, Javaid K, Kayani A, Mutti M, Nadeem MA, Shakur-Still H, Stanworth S, Veitch A, Roberts I; HALT-IT Trial Collaborators.

Trials. 2019 Jul 30;20(1):467. doi: 10.1186/s13063-019-3561-7.

18.

Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.

Sprigg N, Flaherty K, Appleton JP, Al-Shahi Salman R, Bereczki D, Beridze M, Ciccone A, Collins R, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Karlinski M, Krishnan K, Laska AC, Law ZK, Ovesen C, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Peters N, Scutt P, Thanabalan J, Werring D, Whynes D, Woodhouse L, Bath PM.

Health Technol Assess. 2019 Jul;23(35):1-48. doi: 10.3310/hta23350.

19.

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH.

Cancer Cell. 2019 Aug 12;36(2):123-138.e10. doi: 10.1016/j.ccell.2019.06.007. Epub 2019 Jul 11. Erratum in: Cancer Cell. 2019 Sep 16;36(3):340.

PMID:
31303423
20.

Reply to Milan Hora's Letter to the Editor re: Philip S. Macklin, Mark E. Sullivan, Charles R. Tapping, et al. Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre. Eur Urol 2019;75:861-7.

Macklin PS, Sullivan ME, Tapping CR, Webster GM, Roberts ISD, Verrill CL, Browning L.

Eur Urol. 2019 Oct;76(4):e97. doi: 10.1016/j.eururo.2019.06.020. Epub 2019 Jun 27. No abstract available.

PMID:
31255422
21.

No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial.

Dallaku K, Shakur-Still H, Beaumont D, Roberts I, Huque S, Delius M, Holdenrieder S, Gliozheni O, Mansmann U.

Wellcome Open Res. 2019 Feb 5;4:21. doi: 10.12688/wellcomeopenres.14977.1. eCollection 2019.

22.

The effectiveness and safety of anti-fibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis.

Ker K, Prieto-Merino D, Sprigg N, Mahmood A, Bath P, Kang Law Z, Flaherty K, Roberts I.

Version 2. Wellcome Open Res. 2019 Jun 11 [revised 2019 Jan 1];2:120. doi: 10.12688/wellcomeopenres.13262.3. eCollection 2017.

23.

Trial management: we need a cadre of high-class triallists to deliver the answers that patients need.

Beaumont D, Arribas M, Frimley L, Balogun E, Roberts I, Shakur-Still H.

Trials. 2019 Jun 13;20(1):354. doi: 10.1186/s13063-019-3451-z.

24.

Death and Rebirth of the Autopsy.

Roberts I.

Med Leg J. 2019 Jun;87(2):53-64. doi: 10.1177/0025817219844173. Epub 2019 Jun 10. No abstract available.

PMID:
31179879
25.

Odd combinations-coexistence of anti-glomerular basement membrane disease and Sjögren's syndrome.

Ahmed A, Ahmad N, Dibbur V, Price E, Roberts ISD.

Rheumatology (Oxford). 2019 Dec 1;58(12):2339-2342. doi: 10.1093/rheumatology/kez208. No abstract available.

PMID:
31170292
26.

Prognostic model for traumatic death due to bleeding: cross-sectional international study.

Ageron FX, Gayet-Ageron A, Steyerberg E, Bouzat P, Roberts I.

BMJ Open. 2019 May 28;9(5):e026823. doi: 10.1136/bmjopen-2018-026823.

27.

Long term outcomes in monoclonal gammopathy of renal significance.

Khera A, Panitsas F, Djebbari F, Kimberger K, Stern S, Quinn J, Rabin N, Kothari J, Alchi B, Haynes R, Winearls C, Roberts I, Ramasamy K.

Br J Haematol. 2019 Sep;186(5):706-716. doi: 10.1111/bjh.15987. Epub 2019 May 29.

PMID:
31141168
28.

Tranexamic acid for post-partum haemorrhage: What, who and when.

Brenner A, Ker K, Shakur-Still H, Roberts I.

Best Pract Res Clin Obstet Gynaecol. 2019 Nov;61:66-74. doi: 10.1016/j.bpobgyn.2019.04.005. Epub 2019 Apr 30. Review.

29.

Germline selection shapes human mitochondrial DNA diversity.

Wei W, Tuna S, Keogh MJ, Smith KR, Aitman TJ, Beales PL, Bennett DL, Gale DP, Bitner-Glindzicz MAK, Black GC, Brennan P, Elliott P, Flinter FA, Floto RA, Houlden H, Irving M, Koziell A, Maher ER, Markus HS, Morrell NW, Newman WG, Roberts I, Sayer JA, Smith KGC, Taylor JC, Watkins H, Webster AR, Wilkie AOM, Williamson C; NIHR BioResource–Rare Diseases; 100,000 Genomes Project–Rare Diseases Pilot, Ashford S, Penkett CJ, Stirrups KE, Rendon A, Ouwehand WH, Bradley JR, Raymond FL, Caulfield M, Turro E, Chinnery PF.

Science. 2019 May 24;364(6442). pii: eaau6520. doi: 10.1126/science.aau6520. Epub 2019 May 23.

30.

Affect and Decision Making: Insights and Predictions from Computational Models.

Roberts ID, Hutcherson CA.

Trends Cogn Sci. 2019 Jul;23(7):602-614. doi: 10.1016/j.tics.2019.04.005. Epub 2019 May 16. Review.

PMID:
31104816
31.

Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage.

Cornelissen L, Woodd S, Shakur-Still H, Fawole B, Noor S, Etuk S, Akintan AL, Chaudhri R, Roberts I.

Int J Gynaecol Obstet. 2019 Aug;146(2):231-237. doi: 10.1002/ijgo.12860. Epub 2019 Jun 5.

32.

Fibroblast migration correlates with matrix softness. A study in knob-hole engineered fibrin.

Leon-Valdivieso CY, Wedgwood J, Lallana E, Donno R, Roberts I, Ghibaudi M, Tirella A, Tirelli N.

APL Bioeng. 2018 Jul 17;2(3):036102. doi: 10.1063/1.5022841. eCollection 2018 Sep.

33.

Tranexamic acid through intravenous, intramuscular and oral routes: an individual participant data meta-analysis of pharmacokinetic studies in healthy volunteers.

Grassin-Delyle S, Semeraro M, Foissac F, Bouazza N, Shakur-Still H, Roberts I, Treluyer JM, Urien S.

Fundam Clin Pharmacol. 2019 Dec;33(6):670-678. doi: 10.1111/fcp.12474. Epub 2019 May 14.

PMID:
31013357
34.

Impaired cellular and humoral immunity is a feature of Diamond-Blackfan anaemia; experience of 107 unselected cases in the United Kingdom.

Iskander D, Roberts I, Rees C, Szydlo R, Alikian M, Neale M, Harrington Y, Kelleher P, Karadimitris A, de la Fuente J.

Br J Haematol. 2019 Jul;186(2):321-326. doi: 10.1111/bjh.15915. Epub 2019 Apr 13.

PMID:
30980390
35.

A Novel Deletion in the RPL5 Gene in a Lebanese Child With Diamond Blackfan Anemia Unresponsive to Steroid Treatment.

Farah RA, Kamel L, Roy N, Proven M, Wray K, Roberts I, Wlodarski MW.

J Pediatr Hematol Oncol. 2019 Mar 29. doi: 10.1097/MPH.0000000000001435. [Epub ahead of print]

PMID:
30933022
36.

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.

Hua P, Kronsteiner B, van der Garde M, Ashley N, Hernandez D, Tarunina M, Hook L, Choo Y, Roberts I, Mead A, Watt SM.

Sci Rep. 2019 Mar 28;9(1):5300. doi: 10.1038/s41598-019-41803-z.

37.

Super-Resolution Fluorescence Microscopy Study of the Production of K1 Capsules by Escherichia coli: Evidence for the Differential Distribution of the Capsule at the Poles and the Equator of the Cell.

Phanphak S, Georgiades P, Li R, King J, Roberts IS, Waigh TA.

Langmuir. 2019 Apr 23;35(16):5635-5646. doi: 10.1021/acs.langmuir.8b04122. Epub 2019 Apr 9.

38.

Oxytocin and the altruistic 'Goldilocks zone'.

Roberts ID, Teoh YY, Hutcherson CA.

Nat Neurosci. 2019 Apr;22(4):510-512. doi: 10.1038/s41593-019-0362-y. No abstract available.

PMID:
30911180
39.

Subtilase activity and gene expression during germination and seedling growth in barley.

Galotta MF, Pugliese P, Gutiérrez-Boem FH, Veliz CG, Criado MV, Caputo C, Echeverria M, Roberts IN.

Plant Physiol Biochem. 2019 Jun;139:197-206. doi: 10.1016/j.plaphy.2019.03.021. Epub 2019 Mar 16.

PMID:
30908971
40.

Adenovirus 5 recovery using nanofiber ion-exchange adsorbents.

Turnbull J, Wright B, Green NK, Tarrant R, Roberts I, Hardick O, Bracewell DG.

Biotechnol Bioeng. 2019 Jul;116(7):1698-1709. doi: 10.1002/bit.26972. Epub 2019 Mar 28.

PMID:
30883678
41.

Erratum.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Maria Asunis A, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez E, Haider SA, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2019 Mar 16. pii: gfz001. doi: 10.1093/ndt/gfz001. [Epub ahead of print] No abstract available.

PMID:
30879042
42.

Acetaminophen influences social and economic trust.

Roberts ID, Krajbich I, Way BM.

Sci Rep. 2019 Mar 11;9(1):4060. doi: 10.1038/s41598-019-40093-9.

43.

Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis.

Gorvin CM, Loh NY, Stechman MJ, Falcone S, Hannan FM, Ahmad BN, Piret SE, Reed AA, Jeyabalan J, Leo P, Marshall M, Sethi S, Bass P, Roberts I, Sanderson J, Wells S, Hough TA, Bentley L, Christie PT, Simon MM, Mallon AM, Schulz H, Cox RD, Brown MA, Huebner N, Brown SD, Thakker RV.

J Bone Miner Res. 2019 Jul;34(7):1324-1335. doi: 10.1002/jbmr.3695. Epub 2019 Mar 4.

44.

Reply to Maxine G. Tran, Ravi Barod, and Axel Bex's Letter to the Editor re: Philip S. Macklin, Mark E. Sullivan, Charles R. Tapping, et al. Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre. Eur Urol 2019;75:861-7.

Macklin PS, Sullivan ME, Tapping CR, Webster GM, Roberts ISD, Verrill CL, Browning L.

Eur Urol. 2019 Jun;75(6):e177-e178. doi: 10.1016/j.eururo.2019.02.029. Epub 2019 Mar 1. No abstract available.

PMID:
30827695
45.

Fabrication and characterisation of 3D printed MWCNT composite porous scaffolds for bone regeneration.

Huang B, Vyas C, Roberts I, Poutrel QA, Chiang WH, Blaker JJ, Huang Z, Bártolo P.

Mater Sci Eng C Mater Biol Appl. 2019 May;98:266-278. doi: 10.1016/j.msec.2018.12.100. Epub 2018 Dec 28.

PMID:
30813027
46.

Microrheology and Spatial Heterogeneity of Staphylococcus aureus Biofilms Modulated by Hydrodynamic Shear and Biofilm-Degrading Enzymes.

Hart JW, Waigh TA, Lu JR, Roberts IS.

Langmuir. 2019 Mar 5;35(9):3553-3561. doi: 10.1021/acs.langmuir.8b04252. Epub 2019 Feb 15.

47.

Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.

Agraz-Doblas A, Bueno C, Bashford-Rogers R, Roy A, Schneider P, Bardini M, Ballerini P, Cazzaniga G, Moreno T, Revilla C, Gut M, Valsecchi MG, Roberts I, Pieters R, De Lorenzo P, Varela I, Menendez P, Stam RW.

Haematologica. 2019 Jun;104(6):1176-1188. doi: 10.3324/haematol.2018.206375. Epub 2019 Jan 24.

48.

Effectiveness and cost-effectiveness of a Yoga-based Cardiac Rehabilitation (Yoga-CaRe) program following acute myocardial infarction: Study rationale and design of a multi-center randomized controlled trial.

Chandrasekaran AM, Kinra S, Ajay VS, Chattopadhyay K, Singh K, Singh K, Praveen PA, Soni D, Devarajan R, Kondal D, Manchanda SC, Hughes AD, Chaturvedi N, Roberts I, Pocock S, Ebrahim S, Reddy KS, Tandon N, Prabhakaran D; Yoga-CaRe Trial Team.

Int J Cardiol. 2019 Apr 1;280:14-18. doi: 10.1016/j.ijcard.2019.01.012. Epub 2019 Jan 7.

PMID:
30661847
49.

The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial.

Nishijima DK, Kuppermann N, Roberts I, VanBuren JM, Tancredi DJ.

Ann Emerg Med. 2019 Jul;74(1):79-87. doi: 10.1016/j.annemergmed.2018.11.018. Epub 2019 Jan 12.

PMID:
30642657
50.

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial.

Ker K, Roberts I, Chaudhri R, Fawole B, Beaumont D, Balogun E, Prowse D, Pepple T, Javaid K, Kayani A, Arulkumaran S, Bates I, Shakur-Still H; WOMAN-2 trial collaborators.

Trials. 2018 Dec 29;19(1):712. doi: 10.1186/s13063-018-3081-x.

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