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Items: 1 to 50 of 315

1.

A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood.

Bedke N, Swindle EJ, Molnar C, Holt PG, Strickland DH, Roberts GC, Morris R, Holgate ST, Davies DE, Blume C.

J Immunol Methods. 2019 Nov 9:112703. doi: 10.1016/j.jim.2019.112703. [Epub ahead of print]

PMID:
31711888
2.

EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma.

Venter C, Greenhawt M, Meyer RW, Agostoni C, Reese I, du Toit G, Feeney M, Maslin K, Nwaru BI, Roduit C, Untersmayr E, Vlieg-Boerstra B, Pali-Schöll I, Roberts GC, Smith P, Akdis CA, Agache I, Ben-Adallah M, Bischoff S, Frei R, Garn H, Grimshaw K, Hoffmann-Sommergruber K, Lunjani N, Muraro A, Poulsen LK, Renz H, Sokolowska M, Stanton C, O'Mahony L.

Allergy. 2019 Sep 14. doi: 10.1111/all.14051. [Epub ahead of print]

PMID:
31520486
3.

EAACI Guidelines on Allergen Immunotherapy: House dust mite-driven allergic asthma.

Agache I, Lau S, Akdis CA, Smolinska S, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci O, Mosges R, Palomares O, Papadopoulos NG, Sokolowska M, Angier E, Fernandez-Rivas M, Pajno G, Pfaar O, Roberts GC, Ryan D, Sturm GJ, van Ree R, Varga EM, van Wijk RG, Yepes-Nuñez JJ, Jutel M.

Allergy. 2019 May;74(5):855-873. doi: 10.1111/all.13749.

PMID:
31095767
4.

EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis.

Venter C, Meyer RW, Nwaru BI, Roduit C, Untersmayr E, Adel-Patient K, Agache I, Agostoni C, Akdis CA, Bischoff SC, du Toit G, Feeney M, Frei R, Garn H, Greenhawt M, Hoffmann-Sommergruber K, Lunjani N, Maslin K, Mills C, Muraro A, Pali-Schöll I, Poulson LK, Reese I, Renz H, Roberts GC, Smith P, Smolinska S, Sokolowska M, Stanton C, Vlieg-Boerstra B, O'Mahony L.

Allergy. 2019 Aug;74(8):1429-1444. doi: 10.1111/all.13764. Epub 2019 May 3.

PMID:
31032983
5.

Correction: The effect of a programme to improve men's sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial.

Wyke S, Bunn C, Andersen E, Silva MN, van Nassau F, McSkimming P, Kolovos S, Gill JMR, Gray CM, Hunt K, Anderson AS, Bosmans J, Jelsma JGM, Kean S, Lemyre N, Loudon DW, Macaulay L, Maxwell DJ, McConnachie A, Mutrie N, Sanden MN, Pereira HV, Philpott M, Roberts GC, Rooksby J, Røynesdal ØB, Sattar N, Sørensen M, Teixeira PJ, Treweek S, van Achterberg T, van de Glind I, van Mechelen W, van der Ploeg HP.

PLoS Med. 2019 Mar 14;16(3):e1002772. doi: 10.1371/journal.pmed.1002772. eCollection 2019 Mar.

6.

The effect of a programme to improve men's sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial.

Wyke S, Bunn C, Andersen E, Silva MN, van Nassau F, McSkimming P, Kolovos S, Gill JMR, Gray CM, Hunt K, Anderson AS, Bosmans J, Jelsma JGM, Kean S, Lemyre N, Loudon DW, Macaulay L, Maxwell DJ, McConnachie A, Mutrie N, Nijhuis-van der Sanden M, Pereira HV, Philpott M, Roberts GC, Rooksby J, Røynesdal ØB, Sattar N, Sørensen M, Teixeira PJ, Treweek S, van Achterberg T, van de Glind I, van Mechelen W, van der Ploeg HP.

PLoS Med. 2019 Feb 5;16(2):e1002736. doi: 10.1371/journal.pmed.1002736. eCollection 2019 Feb. Erratum in: PLoS Med. 2019 Mar 14;16(3):e1002772.

7.

Who are the high achievers at work? Perceived motivational climate, goal orientation profiles, and work performance.

Nerstad CGL, Richardsen AM, Roberts GC.

Scand J Psychol. 2018 Dec;59(6):661-677. doi: 10.1111/sjop.12490. Epub 2018 Sep 28.

PMID:
30265374
8.

Solution structure of the cytochrome P450 reductase-cytochrome c complex determined by neutron scattering.

Freeman SL, Martel A, Devos JM, Basran J, Raven EL, Roberts GCK.

J Biol Chem. 2018 Apr 6;293(14):5210-5219. doi: 10.1074/jbc.RA118.001941. Epub 2018 Feb 23.

9.

Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research.

Roberts GC, Zothner C, Remenyi R, Merits A, Stonehouse NJ, Harris M.

Sci Rep. 2017 Nov 7;7(1):14641. doi: 10.1038/s41598-017-15269-w.

10.

Manipulation of both virus- and cell-specific factors is required for robust transient replication of a hepatitis C virus genotype 3a sub-genomic replicon.

Kelly L, Badhan A, Roberts GC, Mbisa JL, Harris M.

J Gen Virol. 2017 Oct 6. doi: 10.1099/jgv.0.000932. [Epub ahead of print]

11.

Orchestrated Domain Movement in Catalysis by Cytochrome P450 Reductase.

Freeman SL, Martel A, Raven EL, Roberts GCK.

Sci Rep. 2017 Aug 29;7(1):9741. doi: 10.1038/s41598-017-09840-8.

12.

Challenges in the implementation of EAACI guidelines on allergen immunotherapy: A global perspective on the regulation of allergen products.

Bonertz A, Roberts GC, Hoefnagel M, Timon M, Slater JE, Rabin RL, Bridgewater J, Pini C, Pfaar O, Akdis C, Goldstein J, Poulsen LK, van Ree R, Rhyner C, Barber D, Palomares O, Sheikh A, Pawankar R, Hamerlijnk D, Klimek L, Agache I, Angier E, Casale T, Fernandez-Rivas M, Halken S, Jutel M, Lau S, Pajno G, Sturm G, Varga EM, Gerth van Wijk R, Bonini S, Muraro A, Vieths S.

Allergy. 2018 Jan;73(1):64-76. doi: 10.1111/all.13266. Epub 2017 Aug 30. Review.

13.

SNAP-tagged Chikungunya Virus Replicons Improve Visualisation of Non-Structural Protein 3 by Fluorescence Microscopy.

Remenyi R, Roberts GC, Zothner C, Merits A, Harris M.

Sci Rep. 2017 Jul 18;7(1):5682. doi: 10.1038/s41598-017-05820-0.

14.

Study protocol of European Fans in Training (EuroFIT): a four-country randomised controlled trial of a lifestyle program for men delivered in elite football clubs.

van Nassau F, van der Ploeg HP, Abrahamsen F, Andersen E, Anderson AS, Bosmans JE, Bunn C, Chalmers M, Clissmann C, Gill JM, Gray CM, Hunt K, Jelsma JG, La Guardia JG, Lemyre PN, Loudon DW, Macaulay L, Maxwell DJ, McConnachie A, Martin A, Mourselas N, Mutrie N, Nijhuis-van der Sanden R, O'Brien K, Pereira HV, Philpott M, Roberts GC, Rooksby J, Rost M, Røynesdal Ø, Sattar N, Silva MN, Sorensen M, Teixeira PJ, Treweek S, van Achterberg T, van de Glind I, van Mechelen W, Wyke S.

BMC Public Health. 2016 Jul 19;16:598. doi: 10.1186/s12889-016-3255-y.

15.

An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast Cancer.

Roberts GC, Morris PG, Moss MA, Maltby SL, Palmer CA, Nash CE, Smart E, Holliday DL, Speirs V.

PLoS One. 2016 Jun 14;11(6):e0157004. doi: 10.1371/journal.pone.0157004. eCollection 2016.

16.

The Role of Active Site Flexible Loops in Catalysis and of Zinc in Conformational Stability of Bacillus cereus 569/H/9 β-Lactamase.

Montagner C, Nigen M, Jacquin O, Willet N, Dumoulin M, Karsisiotis AI, Roberts GC, Damblon C, Redfield C, Matagne A.

J Biol Chem. 2016 Jul 29;291(31):16124-37. doi: 10.1074/jbc.M116.719005. Epub 2016 May 27.

17.

Prospective food diaries demonstrate breastfeeding characteristics in a UK birth cohort.

Grimshaw KE, Aksoy B, Palmer A, Jenner K, Oliver EM, Maskell J, Kemp T, Foote KD, Roberts GC, Ellahi B, Margetts BM.

Matern Child Nutr. 2015 Oct;11(4):703-11. doi: 10.1111/mcn.12052. Epub 2013 Jun 18.

PMID:
26419217
18.

A variety of roles for versatile zinc in metallo-β-lactamases.

Karsisiotis AI, Damblon CF, Roberts GC.

Metallomics. 2014 Jul;6(7):1181-97. doi: 10.1039/c4mt00066h. Review.

PMID:
24696003
19.

Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid.

Karsisiotis AI, Damblon CF, Roberts GC.

Biochem J. 2013 Dec 15;456(3):397-407. doi: 10.1042/BJ20131003.

20.

Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase.

Huang WC, Ellis J, Moody PC, Raven EL, Roberts GC.

Structure. 2013 Sep 3;21(9):1581-9. doi: 10.1016/j.str.2013.06.022. Epub 2013 Aug 1.

21.

Complete ¹H, ¹⁵N, and ¹³C resonance assignments of Bacillus cereus metallo-β-lactamase and its complex with the inhibitor R-thiomandelic acid.

Karsisiotis AI, Damblon C, Roberts GC.

Biomol NMR Assign. 2014 Oct;8(2):313-8. doi: 10.1007/s12104-013-9507-1. Epub 2013 Jul 10.

22.

Bringing the ocean into the laboratory to probe the chemical complexity of sea spray aerosol.

Prather KA, Bertram TH, Grassian VH, Deane GB, Stokes MD, Demott PJ, Aluwihare LI, Palenik BP, Azam F, Seinfeld JH, Moffet RC, Molina MJ, Cappa CD, Geiger FM, Roberts GC, Russell LM, Ault AP, Baltrusaitis J, Collins DB, Corrigan CE, Cuadra-Rodriguez LA, Ebben CJ, Forestieri SD, Guasco TL, Hersey SP, Kim MJ, Lambert WF, Modini RL, Mui W, Pedler BE, Ruppel MJ, Ryder OS, Schoepp NG, Sullivan RC, Zhao D.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7550-5. doi: 10.1073/pnas.1300262110. Epub 2013 Apr 25.

23.

RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL.

J Biol Chem. 2013 Mar 22;288(12):8238-49. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6.

24.

Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years.

Pike KC, Calder PC, Inskip HM, Robinson SM, Roberts GC, Cooper C, Godfrey KM, Lucas JS.

Clin Dev Immunol. 2012;2012:474613. doi: 10.1155/2012/474613. Epub 2012 Sep 25.

25.

Coaching communication issues with elite female athletes: two Norwegian case studies.

Kristiansen E, Tomten SE, Hanstad DV, Roberts GC.

Scand J Med Sci Sports. 2012 Dec;22(6):e156-67. doi: 10.1111/j.1600-0838.2012.01521.x. Epub 2012 Aug 27.

PMID:
22925166
26.

Measurements of aerosol chemistry during new particle formation events at a remote rural mountain site.

Creamean JM, Ault AP, Ten Hoeve JE, Jacobson MZ, Roberts GC, Prather KA.

Environ Sci Technol. 2011 Oct 1;45(19):8208-16. doi: 10.1021/es103692f. Epub 2011 Sep 1.

PMID:
21809849
27.

Detection of a protein conformational equilibrium by electrospray ionisation-ion mobility-mass spectrometry.

Jenner M, Ellis J, Huang WC, Lloyd Raven E, Roberts GC, Oldham NJ.

Angew Chem Int Ed Engl. 2011 Aug 29;50(36):8291-4. doi: 10.1002/anie.201101077. Epub 2011 Jun 17. No abstract available.

PMID:
21688358
28.

Highly accurate prediction of food challenge outcome using routinely available clinical data.

DunnGalvin A, Daly D, Cullinane C, Stenke E, Keeton D, Erlewyn-Lajeunesse M, Roberts GC, Lucas J, Hourihane JO.

J Allergy Clin Immunol. 2011 Mar;127(3):633-9.e1-3. doi: 10.1016/j.jaci.2010.12.004.

PMID:
21377032
29.

Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis.

Huang WC, Cullis PM, Raven EL, Roberts GC.

Metallomics. 2011 Apr;3(4):410-6. doi: 10.1039/c0mt00082e. Epub 2011 Jan 17.

PMID:
21240430
30.

Organizational and media stress among professional football players: testing an achievement goal theory model.

Kristiansen E, Halvari H, Roberts GC.

Scand J Med Sci Sports. 2012 Aug;22(4):569-79. doi: 10.1111/j.1600-0838.2010.01259.x. Epub 2011 Jan 7.

PMID:
21210857
31.

Breastfeeding and reported morbidity during infancy: findings from the Southampton Women's Survey.

Fisk CM, Crozier SR, Inskip HM, Godfrey KM, Cooper C, Roberts GC, Robinson SM; Southampton Women's Survey Study Group.

Matern Child Nutr. 2011 Jan;7(1):61-70. doi: 10.1111/j.1740-8709.2010.00241.x.

PMID:
21143586
32.

The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL.

Structure. 2010 Oct 13;18(10):1289-99. doi: 10.1016/j.str.2010.07.011.

33.

Kinetics of electron transfer between NADPH-cytochrome P450 reductase and cytochrome P450 3A4.

Farooq Y, Roberts GC.

Biochem J. 2010 Dec 15;432(3):485-93. doi: 10.1042/BJ20100744.

PMID:
20879989
34.

Central region of talin has a unique fold that binds vinculin and actin.

Gingras AR, Bate N, Goult BT, Patel B, Kopp PM, Emsley J, Barsukov IL, Roberts GC, Critchley DR.

J Biol Chem. 2010 Sep 17;285(38):29577-87. doi: 10.1074/jbc.M109.095455. Epub 2010 Jul 7.

35.

The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.

Goult BT, Gingras AR, Bate N, Barsukov IL, Critchley DR, Roberts GC.

FEBS Lett. 2010 Jun 3;584(11):2237-41. doi: 10.1016/j.febslet.2010.04.028. Epub 2010 Apr 20.

36.

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.

Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL.

EMBO J. 2010 Mar 17;29(6):1069-80. doi: 10.1038/emboj.2010.4. Epub 2010 Feb 11.

37.

A new look at the pathogenesis of asthma.

Holgate ST, Arshad HS, Roberts GC, Howarth PH, Thurner P, Davies DE.

Clin Sci (Lond). 2009 Dec 23;118(7):439-50. doi: 10.1042/CS20090474. Review.

38.

Domain motion in cytochrome P450 reductase: conformational equilibria revealed by NMR and small-angle x-ray scattering.

Ellis J, Gutierrez A, Barsukov IL, Huang WC, Grossmann JG, Roberts GC.

J Biol Chem. 2009 Dec 25;284(52):36628-37. doi: 10.1074/jbc.M109.054304. Epub 2009 Oct 26.

39.

The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.

Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR.

J Mol Biol. 2009 Dec 18;394(5):944-56. doi: 10.1016/j.jmb.2009.09.061. Epub 2009 Oct 3.

40.

Young elite athletes and social support: coping with competitive and organizational stress in "Olympic" competition.

Kristiansen E, Roberts GC.

Scand J Med Sci Sports. 2010 Aug;20(4):686-95. doi: 10.1111/j.1600-0838.2009.00950.x. Epub 2009 Sep 28.

PMID:
19793212
41.

Timescale for hygroscopic conversion of calcite mineral particles through heterogeneous reaction with nitric acid.

Sullivan RC, Moore MJ, Petters MD, Kreidenweis SM, Roberts GC, Prather KA.

Phys Chem Chem Phys. 2009 Sep 28;11(36):7826-37. doi: 10.1039/b904217b. Epub 2009 Jun 25.

PMID:
19727489
42.

Positively cooperative binding of zinc ions to Bacillus cereus 569/H/9 beta-lactamase II suggests that the binuclear enzyme is the only relevant form for catalysis.

Jacquin O, Balbeur D, Damblon C, Marchot P, De Pauw E, Roberts GC, Frère JM, Matagne A.

J Mol Biol. 2009 Oct 9;392(5):1278-91. doi: 10.1016/j.jmb.2009.07.092. Epub 2009 Aug 6.

PMID:
19665032
43.

Structural and biophysical properties of the integrin-associated cytoskeletal protein talin.

Roberts GC, Critchley DR.

Biophys Rev. 2009 Jul;1(2):61-69. Epub 2009 Jun 4.

44.

NMR assignment of the C-terminal actin-binding domain of talin.

Goult BT, Gingras AR, Bate N, Roberts GC, Critchley DR, Barsukov IL.

Biomol NMR Assign. 2008 Jun;2(1):17-9. doi: 10.1007/s12104-007-9073-5. Epub 2007 Dec 22.

PMID:
19636914
45.

Structural and biophysical properties of the integrin-associated cytoskeletal protein talin.

Roberts GCK, Critchley DR.

Biophys Rev. 2009 Jul;1(2):61-69. doi: 10.1007/s12551-009-0009-4. Epub 2009 Jun 4. Review.

46.

The structure of an interdomain complex that regulates talin activity.

Goult BT, Bate N, Anthis NJ, Wegener KL, Gingras AR, Patel B, Barsukov IL, Campbell ID, Roberts GC, Critchley DR.

J Biol Chem. 2009 May 29;284(22):15097-106. doi: 10.1074/jbc.M900078200. Epub 2009 Mar 18.

47.

Structural determinants of integrin binding to the talin rod.

Gingras AR, Ziegler WH, Bobkov AA, Joyce MG, Fasci D, Himmel M, Rothemund S, Ritter A, Grossmann JG, Patel B, Bate N, Goult BT, Emsley J, Barsukov IL, Roberts GC, Liddington RC, Ginsberg MH, Critchley DR.

J Biol Chem. 2009 Mar 27;284(13):8866-76. doi: 10.1074/jbc.M805937200. Epub 2009 Jan 27.

48.

Multiple substrate binding by cytochrome P450 3A4: estimation of the number of bound substrate molecules.

Kapelyukh Y, Paine MJ, Maréchal JD, Sutcliffe MJ, Wolf CR, Roberts GC.

Drug Metab Dispos. 2008 Oct;36(10):2136-44. doi: 10.1124/dmd.108.021733. Epub 2008 Jul 21.

PMID:
18645035
49.

Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain.

Wegener KL, Basran J, Bagshaw CR, Campbell ID, Roberts GC, Critchley DR, Barsukov IL.

J Mol Biol. 2008 Sep 26;382(1):112-26. doi: 10.1016/j.jmb.2008.06.087. Epub 2008 Jul 7.

PMID:
18638481
50.

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.

Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ.

Org Biomol Chem. 2008 Jul 7;6(13):2282-94. doi: 10.1039/b802311e. Epub 2008 May 7.

PMID:
18563261

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