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Contribution of Real-Time Xpert MTB/RIF Testing to Establishing Early Diagnosis of Pediatric Extrapulmonary Tuberculosis in a Nonendemic Setting: A Case Series.

Mijović H, Al-Nasser Y, Al-Rawahi GN, Roberts AD.

Pediatr Infect Dis J. 2019 Dec;38(12):1249-1251. doi: 10.1097/INF.0000000000002488.


Graphene-aramid nanocomposite fibres via superacid co-processing.

Roberts AD, Kelly P, Bain J, Morrison JJ, Wimpenny I, Barrow M, Woodward RT, Gresil M, Blanford C, Hay S, Blaker JJ, Yeates SG, Scrutton NS.

Chem Commun (Camb). 2019 Sep 26;55(78):11703-11706. doi: 10.1039/c9cc04548a.


A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.

Bamborough P, Chung CW, Demont EH, Bridges AM, Craggs PD, Dixon DP, Francis P, Furze RC, Grandi P, Jones EJ, Karamshi B, Locke K, Lucas SCC, Michon AM, Mitchell DJ, Pogány P, Prinjha RK, Rau C, Roa AM, Roberts AD, Sheppard RJ, Watson RJ.

J Med Chem. 2019 Aug 22;62(16):7506-7525. doi: 10.1021/acs.jmedchem.9b00673. Epub 2019 Aug 9.


Dose-dependant acute or subacute disease caused by Burkholderia pseudomallei strain NCTC 13392 in a BALB/c aerosol model of infection.

Funnell SGP, Tree JA, Hatch GJ, Bate SR, Hall G, Pearson G, Rayner EL, Roberts ADG, Vipond J.

J Appl Microbiol. 2019 Oct;127(4):1224-1235. doi: 10.1111/jam.14396. Epub 2019 Aug 9.


Synthetic biology for fibres, adhesives and active camouflage materials in protection and aerospace.

Roberts AD, Finnigan W, Wolde-Michael E, Kelly P, Blaker JJ, Hay S, Breitling R, Takano E, Scrutton NS.

MRS Commun. 2019 May 15;9(2):486-504. doi: 10.1557/mrc.2019.35. Epub 2019 Apr 24.


Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites.

Roberts AD, Nair SC, Guerra AJ, Prigge ST.

Traffic. 2019 Aug;20(8):571-582. doi: 10.1111/tra.12656. Epub 2019 Jun 17.


Porous, Aligned, and Biomimetic Fibers of Regenerated Silk Fibroin Produced by Solution Blow Spinning.

Magaz A, Roberts AD, Faraji S, Nascimento TRL, Medeiros ES, Zhang W, Greenhalgh RD, Mautner A, Li X, Blaker JJ.

Biomacromolecules. 2018 Dec 10;19(12):4542-4553. doi: 10.1021/acs.biomac.8b01233. Epub 2018 Nov 27.


Using hyperpolarised NMR and DFT to rationalise the unexpected hydrogenation of quinazoline to 3,4-dihydroquinazoline.

Richards JE, Hooper AJJ, Bayfield OW, Cockett MCR, Dear GJ, Holmes AJ, John RO, Mewis RE, Pridmore N, Roberts AD, Whitwood AC, Duckett SB.

Chem Commun (Camb). 2018 Sep 11;54(73):10375-10378. doi: 10.1039/c8cc04826f.


Split happens: a case of consecutive monozygotic twin pregnancies following elective single-embryo transfer in a 40-year old woman using donor oocytes.

Roberts AD, Schmidt R, Shah M.

J Assist Reprod Genet. 2018 Aug;35(8):1529-1532. doi: 10.1007/s10815-018-1218-1. Epub 2018 Jun 2. No abstract available.


The effect of a non-denaturing detergent and a guanidinium-based inactivation agent on the viability of Ebola virus in mock clinical serum samples.

Burton JE, Easterbrook L, Pitman J, Anderson D, Roddy S, Bailey D, Vipond R, Bruce CB, Roberts AD.

J Virol Methods. 2017 Dec;250:34-40. doi: 10.1016/j.jviromet.2017.09.020. Epub 2017 Sep 20.


Preexposure prophylaxis: a cautionary tale.

Desrosiers AA, Roberts AD, Simon GL.

AIDS. 2017 Sep 24;31(15):2177-2178. doi: 10.1097/QAD.0000000000001624. No abstract available.


High-Surface-Area, Emulsion-Templated Carbon Foams by Activation of polyHIPEs Derived from Pickering Emulsions.

Woodward RT, De Luca F, Roberts AD, Bismarck A.

Materials (Basel). 2016 Sep 14;9(9). pii: E776. doi: 10.3390/ma9090776.


Dose-rate-dependent damage of cerium dioxide in the scanning transmission electron microscope.

Johnston-Peck AC, DuChene JS, Roberts AD, Wei WD, Herzing AA.

Ultramicroscopy. 2016 Nov;170:1-9. doi: 10.1016/j.ultramic.2016.07.002. Epub 2016 Jul 6.


Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.

Roddick KM, Roberts AD, Schellinck HM, Brown RE.

Chem Senses. 2016 Jun;41(5):433-40. doi: 10.1093/chemse/bjw018. Epub 2016 Mar 11.


Repeated high-dose (5 × 10(8) TCID50) toxicity study of a third generation smallpox vaccine (IMVAMUNE) in New Zealand white rabbits.

Tree JA, Hall G, Rees P, Vipond J, Funnell SG, Roberts AD.

Hum Vaccin Immunother. 2016 Jul 2;12(7):1795-801. doi: 10.1080/21645515.2015.1134070.


Elucidation of Drug Metabolite Structural Isomers Using Molecular Modeling Coupled with Ion Mobility Mass Spectrometry.

Reading E, Munoz-Muriedas J, Roberts AD, Dear GJ, Robinson CV, Beaumont C.

Anal Chem. 2016 Feb 16;88(4):2273-80. doi: 10.1021/acs.analchem.5b04068. Epub 2016 Jan 25.


Oxidation-state sensitive imaging of cerium dioxide by atomic-resolution low-angle annular dark field scanning transmission electron microscopy.

Johnston-Peck AC, Winterstein JP, Roberts AD, DuChene JS, Qian K, Sweeny BC, Wei WD, Sharma R, Stach EA, Herzing AA.

Ultramicroscopy. 2016 Mar;162:52-60. doi: 10.1016/j.ultramic.2015.12.004. Epub 2015 Dec 17.


The Effect of Instrumentation on Suture Tensile Strength and Knot Pullout Strength of Common Suture Materials.

Johnson PC, Roberts AD, Hire JM, Mueller TL.

J Surg Educ. 2016 Jan-Feb;73(1):162-5. doi: 10.1016/j.jsurg.2015.08.011. Epub 2015 Sep 28.


HIV infection induces structural and functional changes in high density lipoproteins.

Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML.

Atherosclerosis. 2015 Nov;243(1):19-29. doi: 10.1016/j.atherosclerosis.2015.08.036. Epub 2015 Aug 29.


Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

Demont EH, Chung CW, Furze RC, Grandi P, Michon AM, Wellaway C, Barrett N, Bridges AM, Craggs PD, Diallo H, Dixon DP, Douault C, Emmons AJ, Jones EJ, Karamshi BV, Locke K, Mitchell DJ, Mouzon BH, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ, Bamborough P.

J Med Chem. 2015 Jul 23;58(14):5649-73. doi: 10.1021/acs.jmedchem.5b00772. Epub 2015 Jul 9.


Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange.

Fekete M, Gibard C, Dear GJ, Green GG, Hooper AJ, Roberts AD, Cisnetti F, Duckett SB.

Dalton Trans. 2015 May 7;44(17):7870-80. doi: 10.1039/c5dt00311c.


Sequence of pathogenic events in cynomolgus macaques infected with aerosolized monkeypox virus.

Tree JA, Hall G, Pearson G, Rayner E, Graham VA, Steeds K, Bewley KR, Hatch GJ, Dennis M, Taylor I, Roberts AD, Funnell SG, Vipond J.

J Virol. 2015 Apr;89(8):4335-44. doi: 10.1128/JVI.03029-14. Epub 2015 Feb 4.


Toxicity of sediments from lead-zinc mining areas to juvenile freshwater mussels (Lampsilis siliquoidea) compared to standard test organisms.

Besser JM, Ingersoll CG, Brumbaugh WG, Kemble NE, May TW, Wang N, MacDonald DD, Roberts AD.

Environ Toxicol Chem. 2015 Mar;34(3):626-39. doi: 10.1002/etc.2849. Epub 2015 Feb 10.


van der Waals forces influencing adhesion of cells.

Kendall K, Roberts AD.

Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140078. doi: 10.1098/rstb.2014.0078.


Measured bremsstrahlung photonuclear production of 99Mo ((99m)Tc) with 34 MeV to 1.7 GeV electrons.

Roberts AD, Geddes CGR, Matlis N, Nakamura K, O'Neil JP, Shaw BH, Steinke S, van Tilborg J, Leemans WP.

Appl Radiat Isot. 2015 Feb;96:122-128. doi: 10.1016/j.apradiso.2014.11.008. Epub 2014 Nov 14.


1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.

Demont EH, Bamborough P, Chung CW, Craggs PD, Fallon D, Gordon LJ, Grandi P, Hobbs CI, Hussain J, Jones EJ, Le Gall A, Michon AM, Mitchell DJ, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ.

ACS Med Chem Lett. 2014 Sep 10;5(11):1190-5. doi: 10.1021/ml5002932. eCollection 2014 Nov 13.


CD4 T cells specific for a latency-associated γ-herpesvirus epitope are polyfunctional and cytotoxic.

Freeman ML, Burkum CE, Cookenham T, Roberts AD, Lanzer KG, Huston GE, Jensen MK, Sidney J, Peters B, Kohlmeier JE, Woodland DL, van Dyk LF, Sette A, Blackman MA.

J Immunol. 2014 Dec 15;193(12):5827-34. doi: 10.4049/jimmunol.1302060. Epub 2014 Nov 5.


Promotion of a subdominant CD8 T cell response during murine gammaherpesvirus 68 infection in the absence of CD4 T cell help.

Freeman ML, Roberts AD, Burkum CE, Woodland DL, Blackman MA.

J Virol. 2014 Jul;88(14):7862-9. doi: 10.1128/JVI.00690-14. Epub 2014 Apr 30.


Porous carbon spheres and monoliths: morphology control, pore size tuning and their applications as Li-ion battery anode materials.

Roberts AD, Li X, Zhang H.

Chem Soc Rev. 2014 Jul 7;43(13):4341-56. doi: 10.1039/c4cs00071d. Epub 2014 Apr 7.


Induction of MRSA Biofilm by Low-Dose β-Lactam Antibiotics: Specificity, Prevalence and Dose-Response Effects.

Ng M, Epstein SB, Callahan MT, Piotrowski BO, Simon GL, Roberts AD, Keiser JF, Kaplan JB.

Dose Response. 2013 Jul 25;12(1):152-61. doi: 10.2203/dose-response.13-021.Kaplan. eCollection 2014 Jan.


Disposition and metabolism of darapladib, a lipoprotein-associated phospholipase A2 inhibitor, in humans.

Dave M, Nash M, Young GC, Ellens H, Magee MH, Roberts AD, Taylor MA, Greenhill RW, Boyle GW.

Drug Metab Dispos. 2014 Mar;42(3):415-30. doi: 10.1124/dmd.113.054486. Epub 2013 Dec 30.


Correction: Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged.

Connor LM, Kohlmeier JE, Ryan L, Roberts AD, Cookenham T, Quinn A, Blackman MA, Woodland DL.

Immun Ageing. 2013 Oct 11;10(1):40. doi: 10.1186/1742-4933-10-40. No abstract available.


Assessment of the protective effect of Imvamune and Acam2000 vaccines against aerosolized monkeypox virus in cynomolgus macaques.

Hatch GJ, Graham VA, Bewley KR, Tree JA, Dennis M, Taylor I, Funnell SG, Bate SR, Steeds K, Tipton T, Bean T, Hudson L, Atkinson DJ, McLuckie G, Charlwood M, Roberts AD, Vipond J.

J Virol. 2013 Jul;87(14):7805-15. doi: 10.1128/JVI.03481-12. Epub 2013 May 8.


Poorly water-soluble drug nanoparticles via solvent evaporation in water-soluble porous polymers.

Roberts AD, Zhang H.

Int J Pharm. 2013 Apr 15;447(1-2):241-50. doi: 10.1016/j.ijpharm.2013.03.001. Epub 2013 Mar 13.


Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection.

Brincks EL, Roberts AD, Cookenham T, Sell S, Kohlmeier JE, Blackman MA, Woodland DL.

J Immunol. 2013 Apr 1;190(7):3438-46. doi: 10.4049/jimmunol.1203140. Epub 2013 Mar 6.


Gammaherpesvirus latency induces antibody-associated thrombocytopenia in mice.

Freeman ML, Burkum CE, Lanzer KG, Roberts AD, Pinkevych M, Itakura A, Kummer LW, Szaba FM, Davenport MP, McCarty OJ, Woodland DL, Smiley ST, Blackman MA.

J Autoimmun. 2013 May;42:71-9. doi: 10.1016/j.jaut.2012.11.005. Epub 2012 Dec 14.


Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged.

Connor LM, Kohlmeier JE, Ryan L, Roberts AD, Cookenham T, Blackman MA, Woodland DL.

Immun Ageing. 2012 Dec 18;9(1):28. doi: 10.1186/1742-4933-9-28.


Metabolism and disposition of vilanterol, a long-acting β(2)-adrenoceptor agonist for inhalation use in humans.

Harrell AW, Siederer SK, Bal J, Patel NH, Young GC, Felgate CC, Pearce SJ, Roberts AD, Beaumont C, Emmons AJ, Pereira AI, Kempsford RD.

Drug Metab Dispos. 2013 Jan;41(1):89-100. doi: 10.1124/dmd.112.048603. Epub 2012 Oct 4.


Diabetic foot infections: the role of microbiology and antibiotic treatment.

Roberts AD, Simon GL.

Semin Vasc Surg. 2012 Jun;25(2):75-81. doi: 10.1053/j.semvascsurg.2012.04.010. Review.


Mining Arabidopsis thaliana RNA-seq data with Integrated Genome Browser reveals stress-induced alternative splicing of the putative splicing regulator SR45a.

Gulledge AA, Roberts AD, Vora H, Patel K, Loraine AE.

Am J Bot. 2012 Feb;99(2):219-31. doi: 10.3732/ajb.1100355. Epub 2012 Jan 30.


Inflammatory chemokine receptors regulate CD8(+) T cell contraction and memory generation following infection.

Kohlmeier JE, Reiley WW, Perona-Wright G, Freeman ML, Yager EJ, Connor LM, Brincks EL, Cookenham T, Roberts AD, Burkum CE, Sell S, Winslow GM, Blackman MA, Mohrs M, Woodland DL.

J Exp Med. 2011 Aug 1;208(8):1621-34. doi: 10.1084/jem.20102110. Epub 2011 Jul 25.


Sensitivity of early life stages of freshwater mussels (Unionidae) to acute and chronic toxicity of lead, cadmium, and zinc in water.

Wang N, Ingersoll CG, Ivey CD, Hardesty DK, May TW, Augspurger T, Roberts AD, van Genderen E, Barnhart MC.

Environ Toxicol Chem. 2010 Sep;29(9):2053-63. doi: 10.1002/etc.250.


Nonmalignant clonal expansions of memory CD8+ T cells that arise with age vary in their capacity to mount recall responses to infection.

Kohlmeier JE, Connor LM, Roberts AD, Cookenham T, Martin K, Woodland DL.

J Immunol. 2010 Sep 15;185(6):3456-62. doi: 10.4049/jimmunol.1001745. Epub 2010 Aug 18.


Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge.

Kohlmeier JE, Cookenham T, Roberts AD, Miller SC, Woodland DL.

Immunity. 2010 Jul 23;33(1):96-105. doi: 10.1016/j.immuni.2010.06.016.


The route of priming influences the ability of respiratory virus-specific memory CD8+ T cells to be activated by residual antigen.

Takamura S, Roberts AD, Jelley-Gibbs DM, Wittmer ST, Kohlmeier JE, Woodland DL.

J Exp Med. 2010 Jun 7;207(6):1153-60. doi: 10.1084/jem.20090283. Epub 2010 May 10.


William Smellie and William Hunter: two great obstetricians and anatomists.

Roberts AD, Baskett TF, Calder AA, Arulkumaran S.

J R Soc Med. 2010 May;103(5):205-6. doi: 10.1258/jrsm.2010.100107. No abstract available.


Timing of moderate level prenatal alcohol exposure influences gene expression of sensory processing behavior in rhesus monkeys.

Schneider ML, Moore CF, Larson JA, Barr CS, Dejesus OT, Roberts AD.

Front Integr Neurosci. 2009 Nov 10;3:30. doi: 10.3389/neuro.07.030.2009. eCollection 2009.


CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection.

Kohlmeier JE, Cookenham T, Miller SC, Roberts AD, Christensen JP, Thomsen AR, Woodland DL.

J Immunol. 2009 Oct 1;183(7):4378-84. doi: 10.4049/jimmunol.0902022. Epub 2009 Sep 4.


Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses.

Kaidonis X, Liaw WC, Roberts AD, Ly M, Anson D, Byers S.

Eur J Hum Genet. 2010 Feb;18(2):194-9. doi: 10.1038/ejhg.2009.143. Epub 2009 Aug 19.


Does hypocortisolism predict a poor response to cognitive behavioural therapy in chronic fatigue syndrome?

Roberts AD, Charler ML, Papadopoulos A, Wessely S, Chalder T, Cleare AJ.

Psychol Med. 2010 Mar;40(3):515-22. doi: 10.1017/S0033291709990390. Epub 2009 Jul 17.


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