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Items: 1 to 50 of 4176

1.

A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.

Bamborough P, Chung CW, Demont EH, Bridges AM, Craggs PD, Dixon DP, Francis P, Furze RC, Grandi P, Jones EJ, Karamshi B, Locke K, Lucas SCC, Michon AM, Mitchell DJ, Pogány P, Prinjha RK, Rau C, Roa AM, Roberts AD, Sheppard RJ, Watson RJ.

J Med Chem. 2019 Aug 9. doi: 10.1021/acs.jmedchem.9b00673. [Epub ahead of print]

PMID:
31398032
2.

Better Together? Investigating new control room configurations and reduced crew size in submarine command and control.

Stanton NA, Roberts APJ.

Ergonomics. 2019 Aug 8:1-27. doi: 10.1080/00140139.2019.1654137. [Epub ahead of print]

PMID:
31393223
3.

Feasibility of circulating tumor DNA testing in hepatocellular carcinoma.

Mody K, Kasi PM, Yang JD, Surapaneni PK, Ritter A, Roberts A, Nagy R, Borad MJ.

J Gastrointest Oncol. 2019 Aug;10(4):745-750. doi: 10.21037/jgo.2019.02.10.

4.

A national experiment reveals where a growth mindset improves achievement.

Yeager DS, Hanselman P, Walton GM, Murray JS, Crosnoe R, Muller C, Tipton E, Schneider B, Hulleman CS, Hinojosa CP, Paunesku D, Romero C, Flint K, Roberts A, Trott J, Iachan R, Buontempo J, Yang SM, Carvalho CM, Hahn PR, Gopalan M, Mhatre P, Ferguson R, Duckworth AL, Dweck CS.

Nature. 2019 Aug 7. doi: 10.1038/s41586-019-1466-y. [Epub ahead of print]

PMID:
31391586
5.

Noonan Syndrome.

Allanson JE, Roberts AE.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2001 Nov 15 [updated 2019 Aug 8].

6.

Metasurfaces with Asymmetric Optical Transfer Functions for Optical Signal Processing.

Davis TJ, Eftekhari F, Gómez DE, Roberts A.

Phys Rev Lett. 2019 Jul 3;123(1):013901. doi: 10.1103/PhysRevLett.123.013901.

PMID:
31386393
7.

Susceptibility of frogs to chytridiomycosis correlates with increased levels of immunomodulatory serotonin in the skin.

Claytor SC, Gummer JPA, Grogan LF, Skerratt LF, Webb RJ, Brannelly LA, Berger L, Roberts AA.

Cell Microbiol. 2019 Aug 1:e13089. doi: 10.1111/cmi.13089. [Epub ahead of print]

PMID:
31373151
8.

Polyclonal Heterogeneity: The New Norm for Secondary Clinical Resistance to Targeted Monotherapy in Relapsed Leukemia?

Wei AH, Roberts AW.

Cancer Discov. 2019 Aug;9(8):998-1000. doi: 10.1158/2159-8290.CD-19-0575.

PMID:
31371322
9.

Amino acid-linked platinum(II) compounds: non-canonical nucleoside preferences and influence on glycosidic bond stabilities.

Kimutai B, He CC, Roberts A, Jones ML, Bao X, Jiang J, Yang Z, Rodgers MT, Chow CS.

J Biol Inorg Chem. 2019 Jul 29. doi: 10.1007/s00775-019-01693-y. [Epub ahead of print]

PMID:
31359185
10.

Effect of a Psychiatric Emergency Department Expansion on Acute Mental Health and Addiction Service Use Trends in a Large Urban Center.

Reid N, Castel S, Veldhuizen S, Roberts A, Stergiopoulos V.

Psychiatr Serv. 2019 Jul 30:appips201900112. doi: 10.1176/appi.ps.201900112. [Epub ahead of print]

PMID:
31357920
11.

Impairments in remote memory caused by the lack of Type 2 IP3 receptors.

Pinto-Duarte A, Roberts AJ, Ouyang K, Sejnowski TJ.

Glia. 2019 Oct;67(10):1976-1989. doi: 10.1002/glia.23679. Epub 2019 Jul 26.

PMID:
31348567
12.

Status of HIV-infected patients classified as lost to follow up from a large antiretroviral program in southwest Nigeria.

Balogun M, Meloni ST, Igwilo UU, Roberts A, Okafor I, Sekoni A, Ogunsola F, Kanki PJ, Akanmu S.

PLoS One. 2019 Jul 25;14(7):e0219903. doi: 10.1371/journal.pone.0219903. eCollection 2019.

13.

Phase 1 study of selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL.

Tam CSL, Trotman J, Opat S, Burger JA, Cull G, Gottlieb DJ, Harrup RA, Johnston P, Marlton P, Munoz J, Seymour JF, Simpson DR, Tedeschi A, Elstrom R, Yu Y, Tang Z, Han L, Huang J, Novotny W, Wang L, Roberts AW.

Blood. 2019 Jul 24. pii: blood.2019001160. doi: 10.1182/blood.2019001160. [Epub ahead of print]

PMID:
31340982
14.

Response to the Letter to the Editor by S. Schiffman and H. Nagle: Revisiting the data and information that has collectively established the safety of low/no-calorie sweeteners, including sucralose.

Roberts A, Lobach AR.

Food Chem Toxicol. 2019 Jul 19:110691. doi: 10.1016/j.fct.2019.110691. [Epub ahead of print] No abstract available.

PMID:
31330167
15.

Dose-dependant acute or subacute disease caused by Burkholderia pseudomallei strain NCTC 13392 in a BALB/c aerosol model of infection.

Funnell SGP, Tree JA, Hatch GJ, Bate SR, Hall G, Pearson G, Rayner EL, Roberts ADG, Vipond J.

J Appl Microbiol. 2019 Jul 22. doi: 10.1111/jam.14396. [Epub ahead of print]

PMID:
31330088
16.

Phenotypic Manifestations of Arrhythmogenic Cardiomyopathy in Children and Adolescents.

DeWitt ES, Chandler SF, Hylind RJ, Beausejour Ladouceur V, Blume ED, VanderPluym C, Powell AJ, Fynn-Thompson F, Roberts AE, Sanders SP, Bezzerides V, Lakdawala NK, MacRae CA, Abrams DJ.

J Am Coll Cardiol. 2019 Jul 23;74(3):346-358. doi: 10.1016/j.jacc.2019.05.022.

PMID:
31319917
17.

Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue.

Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK.

Circulation. 2019 Jul 30;140(5):390-404. doi: 10.1161/CIRCULATIONAHA.119.039711. Epub 2019 Jul 17.

PMID:
31311300
18.

Multiplex loop-mediated isothermal amplification (multi-LAMP) assay for rapid detection of mcr-1 to mcr-5 in colistin-resistant bacteria.

Zhong LL, Zhou Q, Tan CY, Roberts AP, El-Sayed Ahmed MAE, Chen G, Dai M, Yang F, Xia Y, Liao K, Liang Y, Yang Y, Feng S, Zheng X, Tian GB.

Infect Drug Resist. 2019 Jul 2;12:1877-1887. doi: 10.2147/IDR.S210226. eCollection 2019.

19.

Predictors of Dropout in Disordered Gamblers in UK Residential Treatment.

Roberts A, Murphy R, Turner J, Sharman S.

J Gambl Stud. 2019 Jul 13. doi: 10.1007/s10899-019-09876-7. [Epub ahead of print]

PMID:
31302803
20.

A novel FAM20C mutation causes a rare form of neonatal lethal Raine syndrome.

Hung CY, Rodriguez M, Roberts A, Bauer M, Mihalek I, Bodamer O.

Am J Med Genet A. 2019 Sep;179(9):1866-1871. doi: 10.1002/ajmg.a.61291. Epub 2019 Jul 11.

PMID:
31297960
21.

Hunger in the midst of plenty: A survey of household food security among urban families in Lagos State, Nigeria.

Roberts AA, Osadare JO, Inem VA.

J Public Health Afr. 2019 Jun 19;10(1):885. doi: 10.4081/jphia.2019.885. eCollection 2019 May 3.

22.

Synthetic biology for fibres, adhesives and active camouflage materials in protection and aerospace.

Roberts AD, Finnigan W, Wolde-Michael E, Kelly P, Blaker JJ, Hay S, Breitling R, Takano E, Scrutton NS.

MRS Commun. 2019 May 15;9(2):486-504. doi: 10.1557/mrc.2019.35. Epub 2019 Apr 24.

PMID:
31281737
23.

Insula serotonin 2A receptor binding and gene expression contribute to serotonin transporter polymorphism anxious phenotype in primates.

Santangelo AM, Sawiak SJ, Fryer T, Hong Y, Shiba Y, Clarke HF, Riss PJ, Ferrari V, Tait R, Suckling J, Aigbirhio FI, Roberts AC.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14761-14768. doi: 10.1073/pnas.1902087116. Epub 2019 Jul 2.

PMID:
31266890
24.

Use of remote monitoring with continuous glucose monitoring in young children with Type 1 diabetes: the parents' perspective.

Burckhardt MA, Fried L, Bebbington K, Hancock M, Nicholas JA, Roberts A, Abraham MB, Davis EA, Jones TW.

Diabet Med. 2019 Jun 30. doi: 10.1111/dme.14061. [Epub ahead of print]

PMID:
31257642
25.

Prevalence and clinical impact of methicillin-resistant Staphylococcus aureus colonization among infants at a level III neonatal intensive care unit.

Lavie-Nevo K, Srigley JA, Al-Rawahi GN, Bone J, Osiovich H, Roberts A, Ting JY.

Am J Infect Control. 2019 Jun 25. pii: S0196-6553(19)30443-2. doi: 10.1016/j.ajic.2019.04.173. [Epub ahead of print]

PMID:
31253554
26.

Trends in Characteristics, Mortality, and Other Outcomes of Patients With Newly Diagnosed Cirrhosis.

Orman ES, Roberts A, Ghabril M, Nephew L, Desai A, Patidar K, Chalasani N.

JAMA Netw Open. 2019 Jun 5;2(6):e196412. doi: 10.1001/jamanetworkopen.2019.6412.

27.

Gene expression signature of atypical breast hyperplasia and regulation by SFRP1.

Gregory KJ, Roberts AL, Conlon EM, Mayfield JA, Hagen MJ, Crisi GM, Bentley BA, Kane JJ, Makari-Judson G, Mason HS, Yu J, Zhu LJ, Simin K, Johnson JPS, Khan A, Schneider BR, Schneider SS, Jerry DJ.

Breast Cancer Res. 2019 Jun 27;21(1):76. doi: 10.1186/s13058-019-1157-5.

28.

Specific Viral Etiologies Are Associated With Outcomes in Pediatric Acute Respiratory Distress Syndrome.

Roberts AL, Sammons JS, Mourani PM, Thomas NJ, Yehya N.

Pediatr Crit Care Med. 2019 Jun 19. doi: 10.1097/PCC.0000000000002008. [Epub ahead of print]

PMID:
31246746
29.

Domain swaps of Arabidopsis secondary wall cellulose synthases to elucidate their class specificity.

Hill JL Jr, Hill AN, Roberts AW, Haigler CH, Tien M.

Plant Direct. 2018 Jul 10;2(7):e00061. doi: 10.1002/pld3.61. eCollection 2018 Jul.

30.

Feasibility of Routine Assessment of Exercise Knowledge and Safety in Youth With Type 1 Diabetes.

Roberts AJ, Mitrovich C, Yi-Frazier JP, Taplin CE.

Diabetes Educ. 2019 Jun 27:145721719860491. doi: 10.1177/0145721719860491. [Epub ahead of print]

PMID:
31244377
31.

Complex Sociality of Wild Chimpanzees Can Emerge from Laterality of Manual Gestures.

Roberts AI, Murray L, Roberts SGB.

Hum Nat. 2019 Jun 24. doi: 10.1007/s12110-019-09347-3. [Epub ahead of print]

PMID:
31236773
32.

Process evaluation of specialist nurse implementation of a soft opt-out organ donation system in Wales.

Noyes J, Mclaughlin L, Morgan K, Roberts A, Moss B, Stephens M, Walton P.

BMC Health Serv Res. 2019 Jun 24;19(1):414. doi: 10.1186/s12913-019-4266-z.

33.

Characterization of a novel venetoclax resistance mutation (BCL2 Phe104Ile) observed in follicular lymphoma.

Blombery P, Birkinshaw RW, Nguyen T, Gong JN, Thompson ER, Xu Z, Westerman DA, Czabotar PE, Dickinson M, Huang DCS, Seymour JF, Roberts AW.

Br J Haematol. 2019 Jun 24. doi: 10.1111/bjh.16069. [Epub ahead of print] No abstract available.

PMID:
31234236
34.

Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease.

Morton SU, Maleyeff L, Wypij D, Yun HJ, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Seidman JG, Seidman CE, Grant PE, Im K.

Cereb Cortex. 2019 Jun 19. pii: bhz101. doi: 10.1093/cercor/bhz101. [Epub ahead of print]

PMID:
31216004
35.

Cas9+ conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond.

Roberts AW, Popov LM, Mitchell G, Ching KL, Licht DJ, Golovkine G, Barton GM, Cox JS.

Elife. 2019 Jun 17;8. pii: e45957. doi: 10.7554/eLife.45957.

36.

Serious illness care Programme UK: assessing the 'face validity', applicability and relevance of the serious illness conversation guide for use within the UK health care setting.

McGlinchey T, Mason S, Coackley A, Roberts A, Maguire M, Sanders J, Maloney F, Block S, Ellershaw J, Kirkbride P.

BMC Health Serv Res. 2019 Jun 13;19(1):384. doi: 10.1186/s12913-019-4209-8.

37.

Uterine and umbilical artery doppler in women with pre-eclampsia and their pregnancy outcomes.

Adekanmi AJ, Roberts A, Akinmoladun JA, Adeyinka AO.

Niger Postgrad Med J. 2019 Apr-Jun;26(2):106-112. doi: 10.4103/npmj.npmj_161_18.

38.

Feasibility and clinical value of circulating tumor DNA testing in patients with gastric adenocarcinomas.

Iqbal M, Roberts A, Starr J, Mody K, Kasi PM.

J Gastrointest Oncol. 2019 Jun;10(3):400-406. doi: 10.21037/jgo.2019.01.14.

39.

Promoter activity of ORF-less gene cassettes isolated from the oral metagenome.

Tansirichaiya S, Mullany P, Roberts AP.

Sci Rep. 2019 Jun 10;9(1):8388. doi: 10.1038/s41598-019-44640-2.

40.

Graphene nanosheets as an electric mediator for ultrafast sensing of urokinase plasminogen activator receptor-A biomarker of cancer.

Roberts A, Tripathi PP, Gandhi S.

Biosens Bioelectron. 2019 May 31;141:111398. doi: 10.1016/j.bios.2019.111398. [Epub ahead of print]

PMID:
31176112
41.

Differential effects of BTK inhibitors ibrutinib and zanubrutinib on NK cell effector function in patients with mantle cell lymphoma.

Flinsenberg TWH, Tromedjo CC, Hu N, Liu Y, Guo Y, Thia KYT, Noori T, Song X, Aw Yeang HX, Tantalo DG, Handunnetti S, Seymour JF, Roberts AW, Ritchie D, Koldej R, Neeson PJ, Wang L, Trapani JA, Tam CS, Voskoboinik I.

Haematologica. 2019 Jun 6. pii: haematol.2019.220590. doi: 10.3324/haematol.2019.220590. [Epub ahead of print]

42.

Efficacy and Safety of Real-Life Usage of MiniMed 670G Automode in Children with Type 1 Diabetes Less than 7 Years Old.

Salehi P, Roberts AJ, Kim GJ.

Diabetes Technol Ther. 2019 Aug;21(8):448-451. doi: 10.1089/dia.2019.0123. Epub 2019 Jun 5.

PMID:
31166801
43.

Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome.

Jaffré F, Miller CL, Schänzer A, Evans T, Roberts AE, Hahn A, Kontaridis MI.

Circulation. 2019 Jul 16;140(3):207-224. doi: 10.1161/CIRCULATIONAHA.118.037227. Epub 2019 Jun 5.

PMID:
31163979
44.

A Focus on the Functions of Area 25.

Alexander L, Clarke HF, Roberts AC.

Brain Sci. 2019 Jun 3;9(6). pii: E129. doi: 10.3390/brainsci9060129. Review.

45.

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.

Birkinshaw RW, Gong JN, Luo CS, Lio D, White CA, Anderson MA, Blombery P, Lessene G, Majewski IJ, Thijssen R, Roberts AW, Huang DCS, Colman PM, Czabotar PE.

Nat Commun. 2019 Jun 3;10(1):2385. doi: 10.1038/s41467-019-10363-1.

46.

Coach knowledge in talent identification: A systematic review and meta-synthesis.

Roberts AH, Greenwood DA, Stanley M, Humberstone C, Iredale F, Raynor A.

J Sci Med Sport. 2019 May 17. pii: S1440-2440(18)31273-8. doi: 10.1016/j.jsams.2019.05.008. [Epub ahead of print] Review.

PMID:
31133481
47.

Gender Diversity Within the American Board of Radiology: History, Current Status, and Future Implications.

Wallner PE, Frey GD, Roberts AC, Canon CL, Jackson VP, Wagner BJ.

J Am Coll Radiol. 2019 May 24. pii: S1546-1440(19)30572-1. doi: 10.1016/j.jacr.2019.05.003. [Epub ahead of print] No abstract available.

PMID:
31132332
48.

Psychosocial correlates in treatment seeking gamblers: Differences in early age onset gamblers vs later age onset gamblers.

Sharman S, Murphy R, Turner J, Roberts A.

Addict Behav. 2019 Oct;97:20-26. doi: 10.1016/j.addbeh.2019.05.013. Epub 2019 May 15.

PMID:
31121560
49.

Medical student exposure to anesthesiology through the Pre-clerkship Residency Exploration Program: impact on career interest and understanding of anesthesiology.

Smyth M, Toguri JT, Dow T, Haupt TS, Roberts A, Raju K.

Can J Anaesth. 2019 Sep;66(9):1126-1128. doi: 10.1007/s12630-019-01403-x. Epub 2019 May 21. No abstract available.

PMID:
31114944
50.

Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized ex vivo Model Simulating Cystic Fibrosis Lung Infection.

Roberts AEL, Powell LC, Pritchard MF, Thomas DW, Jenkins RE.

Front Microbiol. 2019 Apr 24;10:869. doi: 10.3389/fmicb.2019.00869. eCollection 2019.

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