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Items: 1 to 50 of 92

1.

Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases.

Salerno S, La Pietra V, Hyeraci M, Taliani S, Robello M, Barresi E, Milite C, Simorini F, García-Argáez AN, Marinelli L, Novellino E, Da Settimo F, Marini AM, Dalla Via L.

Eur J Med Chem. 2019 Mar 1;165:46-58. doi: 10.1016/j.ejmech.2019.01.015. Epub 2019 Jan 9.

PMID:
30660826
2.

Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes.

Barresi E, Giacomelli C, Daniele S, Tonazzini I, Robello M, Salerno S, Piano I, Cosimelli B, Greco G, Da Settimo F, Martini C, Trincavelli ML, Taliani S.

Bioorg Med Chem. 2018 Dec 1;26(22):5885-5895. doi: 10.1016/j.bmc.2018.10.039. Epub 2018 Nov 1.

PMID:
30415894
3.

Antisecretory Factor Modulates GABAA Receptor Activity in Neurons.

Bazzurro V, Gatta E, Cupello A, Lange S, Robello M.

J Mol Neurosci. 2018 Feb;64(2):312-320. doi: 10.1007/s12031-017-1024-8. Epub 2018 Jan 7.

PMID:
29308551
4.

Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90-231 Neurotoxic Effects in Cerebellar Granule Neurons.

Thellung S, Gatta E, Pellistri F, Villa V, Corsaro A, Nizzari M, Robello M, Florio T.

Neurotox Res. 2017 Oct;32(3):381-397. doi: 10.1007/s12640-017-9749-2. Epub 2017 May 25.

PMID:
28540665
5.

Residence Time, a New parameter to Predict Neurosteroidogenic Efficacy of Translocator Protein (TSPO) Ligands: the Case Study of N,N-Dialkyl-2-arylindol-3-ylglyoxylamides.

Costa B, Taliani S, Da Pozzo E, Barresi E, Robello M, Cavallini C, Cosconati S, Da Settimo F, Novellino E, Martini C.

ChemMedChem. 2017 Aug 22;12(16):1275-1278. doi: 10.1002/cmdc.201700220. Epub 2017 Jun 22.

PMID:
28467680
6.

Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture.

Di Mola A, Gatta E, Petronzi C, Cupello A, De Caprariis P, Robello M, Massa A, Filosa R.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5284-5289. doi: 10.1016/j.bmcl.2016.09.042. Epub 2016 Sep 15.

PMID:
27720293
7.

Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.

Villa V, Thellung S, Bajetto A, Gatta E, Robello M, Novelli F, Tasso B, Tonelli M, Florio T.

Pharmacol Res. 2016 Nov;113(Pt A):500-514. doi: 10.1016/j.phrs.2016.09.010. Epub 2016 Sep 22.

PMID:
27667770
8.

Anticonvulsive Activity in Audiogenic DBA/2 Mice of 1,4-Benzodiazepines and 1,5-Benzodiazepines with Different Activities at Cerebellar Granule Cell GABAA Receptors.

Gatta E, Cupello A, Di Braccio M, Grossi G, Robello M, Scicchitano F, Russo E, De Sarro G.

J Mol Neurosci. 2016 Dec;60(4):539-547. Epub 2016 Sep 15.

PMID:
27629561
9.

Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.

Petroni D, Giacomelli C, Taliani S, Barresi E, Robello M, Daniele S, Bartoli A, Burchielli S, Pardini S, Salvadori PA, Da Settimo F, Martini C, Trincavelli ML, Menichetti L.

Nucl Med Biol. 2016 May;43(5):309-17. doi: 10.1016/j.nucmedbio.2016.02.005. Epub 2016 Feb 27.

PMID:
27150034
10.

Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas.

Daniele S, La Pietra V, Barresi E, Di Maro S, Da Pozzo E, Robello M, La Motta C, Cosconati S, Taliani S, Marinelli L, Novellino E, Martini C, Da Settimo F.

J Med Chem. 2016 May 26;59(10):4526-38. doi: 10.1021/acs.jmedchem.5b01767. Epub 2016 May 3.

PMID:
27050782
11.

Study of the Interaction of 1,4- and 1,5-Benzodiazepines with GABAA Receptors of Rat Cerebellum Granule Cells in Culture.

Nikas P, Gatta E, Cupello A, Di Braccio M, Grossi G, Pellistri F, Robello M.

J Mol Neurosci. 2015 Aug;56(4):768-772. doi: 10.1007/s12031-015-0495-8. Epub 2015 Jan 25.

PMID:
25618569
12.

GABAA Receptors of Cerebellar Granule Cells in Culture: Interaction with Benzodiazepines.

Cupello A, Di Braccio M, Gatta E, Grossi G, Nikas P, Pellistri F, Robello M.

Neurochem Res. 2013 Oct 12. [Epub ahead of print]

PMID:
24122079
13.

Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells.

Pellistri F, Bucciantini M, Invernizzi G, Gatta E, Penco A, Frana AM, Nosi D, Relini A, Regonesi ME, Gliozzi A, Tortora P, Robello M, Stefani M.

Biochim Biophys Acta. 2013 Dec;1833(12):3155-3165. doi: 10.1016/j.bbamcr.2013.08.019. Epub 2013 Sep 11.

14.

Modulation of native GABA(A) receptor activity by triazolo 1,5-benzodiazepines.

Nikas P, Gatta E, Cupello A, Di Braccio M, Grossi G, Pellistri F, Robello M.

Neuroscience. 2013 Jul 23;243:158-64. doi: 10.1016/j.neuroscience.2013.04.007. Epub 2013 Apr 13.

PMID:
23590909
15.

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage.

Molinaro P, Cantile M, Cuomo O, Secondo A, Pannaccione A, Ambrosino P, Pignataro G, Fiorino F, Severino B, Gatta E, Sisalli MJ, Milanese M, Scorziello A, Bonanno G, Robello M, Santagada V, Caliendo G, Di Renzo G, Annunziato L.

Mol Pharmacol. 2013 Jan;83(1):142-56. doi: 10.1124/mol.112.080986. Epub 2012 Oct 11.

PMID:
23066092
16.

Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment.

Thellung S, Gatta E, Pellistri F, Corsaro A, Villa V, Vassalli M, Robello M, Florio T.

Neurotox Res. 2013 May;23(4):301-14. doi: 10.1007/s12640-012-9340-9. Epub 2012 Aug 2.

PMID:
22855343
17.

In vitro study of uptake and synthesis of creatine and its precursors by cerebellar granule cells and astrocytes suggests some hypotheses on the physiopathology of the inherited disorders of creatine metabolism.

Carducci C, Carducci C, Santagata S, Adriano E, Artiola C, Thellung S, Gatta E, Robello M, Florio T, Antonozzi I, Leuzzi V, Balestrino M.

BMC Neurosci. 2012 Apr 26;13:41. doi: 10.1186/1471-2202-13-41.

18.

RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration.

Massone S, Vassallo I, Castelnuovo M, Fiorino G, Gatta E, Robello M, Borghi R, Tabaton M, Russo C, Dieci G, Cancedda R, Pagano A.

J Cell Biol. 2011 May 30;193(5):851-66. doi: 10.1083/jcb.201011053.

19.

17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease.

Massone S, Vassallo I, Fiorino G, Castelnuovo M, Barbieri F, Borghi R, Tabaton M, Robello M, Gatta E, Russo C, Florio T, Dieci G, Cancedda R, Pagano A.

Neurobiol Dis. 2011 Feb;41(2):308-17. doi: 10.1016/j.nbd.2010.09.019. Epub 2010 Oct 1.

PMID:
20888417
20.

An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells.

Castelnuovo M, Massone S, Tasso R, Fiorino G, Gatti M, Robello M, Gatta E, Berger A, Strub K, Florio T, Dieci G, Cancedda R, Pagano A.

FASEB J. 2010 Oct;24(10):4033-46. doi: 10.1096/fj.10-157032. Epub 2010 Jun 25.

PMID:
20581224
21.

New 1,5-benzodiazepine compounds: activity at native GABA(A) receptors.

Gatta E, Cupello A, Di Braccio M, Grossi G, Ferruzzi R, Roma G, Robello M.

Neuroscience. 2010 Mar 31;166(3):917-23. doi: 10.1016/j.neuroscience.2010.01.013. Epub 2010 Jan 20.

PMID:
20096335
22.

GABA(A) receptors of cerebellar granule cells in culture: explanation of overall insensitivity to ethanol.

Gatta E, Cupello A, Pellistri F, Robello M.

Neuroscience. 2009 Sep 15;162(4):1187-91. doi: 10.1016/j.neuroscience.2009.05.031. Epub 2009 May 22.

PMID:
19465089
23.

Nonspecific interaction of prefibrillar amyloid aggregates with glutamatergic receptors results in Ca2+ increase in primary neuronal cells.

Pellistri F, Bucciantini M, Relini A, Nosi D, Gliozzi A, Robello M, Stefani M.

J Biol Chem. 2008 Oct 31;283(44):29950-60. doi: 10.1074/jbc.M803992200. Epub 2008 Aug 1.

24.

Activation of cerebellar granule cells GABA(A) receptors by guanidinoacetate.

Cupello A, Balestrino M, Gatta E, Pellistri F, Siano S, Robello M.

Neuroscience. 2008 Mar 3;152(1):65-9. doi: 10.1016/j.neuroscience.2007.12.018.

PMID:
18222046
25.

ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation.

Thellung S, Villa V, Corsaro A, Pellistri F, Venezia V, Russo C, Aceto A, Robello M, Florio T.

Glia. 2007 Nov 1;55(14):1469-85.

PMID:
17705195
26.

A quantum-dot nanocrystal study of GABAA receptor subunits in living cerebellar granule cells in culture.

Siano S, Cupello A, Pellistri F, Robello M.

Neurochem Res. 2007 Jun;32(6):1024-7. Epub 2007 Mar 31.

PMID:
17401675
27.

SDF-1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent, cytosolic tyrosine kinase Pyk2.

Massa A, Casagrande S, Bajetto A, Porcile C, Barbieri F, Thellung S, Arena S, Pattarozzi A, Gatti M, Corsaro A, Robello M, Schettini G, Florio T.

Ann N Y Acad Sci. 2006 Dec;1090:385-98.

PMID:
17384283
28.

Only high concentrations of ethanol affect GABAA receptors of rat cerebellum granule cells in culture.

Casagrande S, Cupello A, Pellistri F, Robello M.

Neurosci Lett. 2007 Mar 13;414(3):273-6. Epub 2006 Dec 27.

PMID:
17234340
29.

Two-photon analysis of lead accumulation in rat cerebellar granule neurons.

Esposito A, Robello M, Pellistri F, Marchetti C.

Neurochem Res. 2005 Aug;30(8):949-54.

PMID:
16258843
30.

Chemokine stromal cell-derived factor 1alpha induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals.

Florio T, Casagrande S, Diana F, Bajetto A, Porcile C, Zona G, Thellung S, Arena S, Pattarozzi A, Corsaro A, Spaziante R, Robello M, Schettini G.

Mol Pharmacol. 2006 Feb;69(2):539-46. Epub 2005 Oct 28.

PMID:
16258074
31.

Different chloride electrochemical gradients across the plasma membrane in subcellular compartments of rat cerebellum granules.

Pellistri F, Casagrande S, Raimondo M, Cupello A, Robello M.

Neurosci Lett. 2005 Jun 10-17;381(1-2):139-43. Epub 2005 Feb 26.

PMID:
15882805
32.

Calcium accumulation in neurites and cell bodies of rat cerebellar granule cells in culture: effects on GABA(A) receptor function.

Cupello A, Esposito A, Marchetti C, Pellistri F, Robello M.

Amino Acids. 2005 Mar;28(2):177-82. Epub 2005 Feb 18.

PMID:
15714254
34.

Two-photon imaging of calcium accumulation in rat cerebellar granule cells.

Pellistri F, Cupello A, Esposito A, Marchetti C, Robello M.

Neuroreport. 2004 Jan 19;15(1):83-7.

PMID:
15106836
35.

The combined disruption of microfilaments and microtubules affects the distribution and function of GABAA receptors in rat cerebellum granule cells in culture.

Luccardini C, Casagrande S, Cupello A, Pellistri F, Ramoino P, Robello M.

Neurosci Lett. 2004 Apr 8;359(1-2):25-8.

PMID:
15050703
36.
37.

Immunocytochemical study of alpha 1 and beta 2/3 subunits of GABAA receptors in freehand isolated vestibular Deiters' neurons.

Rapallino MV, Cupello A, Luccardini C, Nieddu E, Seitun A, Robello M.

Receptors Channels. 2003;9(2):77-81.

PMID:
12916468
38.

Modulation by Zn(2+) and Cd(2+) of GABA(A) receptors of rat cerebellum granule cells in culture.

Casagrande S, Valle L, Cupello A, Robello M.

Eur Biophys J. 2003 Mar;32(1):40-6. Epub 2002 Nov 14.

PMID:
12632205
39.
40.

Influence of refractive-index mismatch in high-resolution three-dimensional confocal microscopy.

Diaspro A, Federici F, Robello M.

Appl Opt. 2002 Feb 1;41(4):685-90.

PMID:
11993914
41.

Three-dimensional mapping of cholinergic molecules by confocal laser scanning microscopy in sea urchin larvae.

Falugi C, Diaspro A, Angelini C, Pedrotti ML, Raimondo M, Robello M.

Micron. 2002;33(3):233-9.

PMID:
11742747
42.

Regulation of the expression of low affinity GABAA receptors in rat cerebellar granule cells.

Luccardini C, Barilà B, Cupello A, Robello M, Mainardi P.

Amino Acids. 2001;21(2):119-28.

PMID:
11665808
43.

Fluid phase and receptor-mediated endocytosis in Paramecium primaurelia by fluorescence confocal laser scanning microscopy.

Ramoino P, Fronte P, Fato M, Beltrame F, Robello M, Diaspro A.

Eur Biophys J. 2001 Sep;30(5):305-12.

PMID:
11592687
44.

Two-photon microscopy and spectroscopy based on a compact confocal scanning head.

Diaspro A, Chirico G, Federici F, Cannone F, Beretta S, Robello M.

J Biomed Opt. 2001 Jul;6(3):300-10. Review.

PMID:
11516320
45.

Confocal microscopic study of GABA(A) receptors in Xenopus oocytes after rat brain mRNA injection: modulation by tyrosine kinase activity.

Balduzzi R, Cupello A, Diaspro A, Ramoino P, Robello M.

Biochim Biophys Acta. 2001 May 28;1539(1-2):93-100.

46.
47.
48.

Apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126.

Thellung S, Florio T, Villa V, Corsaro A, Arena S, Amico C, Robello M, Salmona M, Forloni G, Bugiani O, Tagliavini F, Schettini G.

Neurobiol Dis. 2000 Aug;7(4):299-309.

PMID:
10964602
49.

GABA(A) receptor modulation in rat cerebellum granule cells.

Cupello A, Robello M.

Receptors Channels. 2000;7(2):151-71.

PMID:
10952091
50.

Modulation by extracellular pH of GABAA receptors expressed in Xenopus oocytes injected with rat brain mRNA.

Robello M, Balduzzi R, Cupello A.

Int J Neurosci. 2000 Jul-Aug;103(1-4):41-51.

PMID:
10938562

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