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Items: 18


FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.

Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM.

Cancer Res. 2018 Aug 1;78(15):4229-4240. doi: 10.1158/0008-5472.CAN-18-0631. Epub 2018 May 29.


WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis.

Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM.

Dev Cell. 2017 Nov 20;43(4):436-448.e6. doi: 10.1016/j.devcel.2017.10.007. Epub 2017 Nov 2.


Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression.

Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM.

Oncogene. 2017 Oct 26;36(43):5958-5968. doi: 10.1038/onc.2017.206. Epub 2017 Jun 26.


The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes.

Sreekumar A, Roarty K, Rosen JM.

Endocr Relat Cancer. 2015 Dec;22(6):T161-76. doi: 10.1530/ERC-15-0263. Epub 2015 Jul 23. Review.


Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.

Roarty K, Shore AN, Creighton CJ, Rosen JM.

J Cell Biol. 2015 Feb 2;208(3):351-66. doi: 10.1083/jcb.201408058. Epub 2015 Jan 26.


STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.

Wei W, Tweardy DJ, Zhang M, Zhang X, Landua J, Petrovic I, Bu W, Roarty K, Hilsenbeck SG, Rosen JM, Lewis MT.

Stem Cells. 2014 Oct;32(10):2571-82. doi: 10.1002/stem.1752.


Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?

Rosen JM, Roarty K.

Breast Cancer Res. 2014 Jan 29;16(1):202. doi: 10.1186/bcr3610. Review.


Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination.

Roarty K, Rosen JM.

Breast Cancer Res. 2013 Dec 23;15(6):322. doi: 10.1186/bcr3592.


Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function.

Pond AC, Bin X, Batts T, Roarty K, Hilsenbeck S, Rosen JM.

Stem Cells. 2013 Jan;31(1):178-89. doi: 10.1002/stem.1266.


Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation.

Shore AN, Kabotyanski EB, Roarty K, Smith MA, Zhang Y, Creighton CJ, Dinger ME, Rosen JM.

PLoS Genet. 2012;8(7):e1002840. doi: 10.1371/journal.pgen.1002840. Epub 2012 Jul 26.


The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.

Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9.


Wnt and mammary stem cells: hormones cannot fly wingless.

Roarty K, Rosen JM.

Curr Opin Pharmacol. 2010 Dec;10(6):643-9. doi: 10.1016/j.coph.2010.07.004. Review.


TGF-beta promotes Th17 cell development through inhibition of SOCS3.

Qin H, Wang L, Feng T, Elson CO, Niyongere SA, Lee SJ, Reynolds SL, Weaver CT, Roarty K, Serra R, Benveniste EN, Cong Y.

J Immunol. 2009 Jul 1;183(1):97-105. doi: 10.4049/jimmunol.0801986. Epub 2009 Jun 17.


Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype.

Roarty K, Baxley SE, Crowley MR, Frost AR, Serra R.

Breast Cancer Res. 2009;11(2):R19. doi: 10.1186/bcr2244. Epub 2009 Apr 3.


Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression.

Brantley EC, Nabors LB, Gillespie GY, Choi YH, Palmer CA, Harrison K, Roarty K, Benveniste EN.

Clin Cancer Res. 2008 Aug 1;14(15):4694-704. doi: 10.1158/1078-0432.CCR-08-0618.


Role for primary cilia in the regulation of mouse ovarian function.

Johnson ET, Nicola T, Roarty K, Yoder BK, Haycraft CJ, Serra R.

Dev Dyn. 2008 Aug;237(8):2053-60. doi: 10.1002/dvdy.21612.


Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth.

Roarty K, Serra R.

Development. 2007 Nov;134(21):3929-39. Epub 2007 Sep 26.


Comparison of daily urine, sweat, and skin swabs among cocaine users.

Kidwell DA, Kidwell JD, Shinohara F, Harper C, Roarty K, Bernadt K, McCaulley RA, Smith FP.

Forensic Sci Int. 2003 Apr 23;133(1-2):63-78.


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