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Items: 40

1.

Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function.

Laustsen A, Bak RO, Krapp C, Kjær L, Egedahl JH, Petersen CC, Pillai S, Tang HQ, Uldbjerg N, Porteus M, Roan NR, Nyegaard M, Denton PW, Jakobsen MR.

Nat Commun. 2018 Aug 30;9(1):3525. doi: 10.1038/s41467-018-05816-y.

2.

Semen inhibits Zika virus infection of cells and tissues from the anogenital region.

Müller JA, Harms M, Krüger F, Groß R, Joas S, Hayn M, Dietz AN, Lippold S, von Einem J, Schubert A, Michel M, Mayer B, Cortese M, Jang KS, Sandi-Monroy N, Deniz M, Ebner F, Vapalahti O, Otto M, Bartenschlager R, Herbeuval JP, Schmidt-Chanasit J, Roan NR, Münch J.

Nat Commun. 2018 Jun 7;9(1):2207. doi: 10.1038/s41467-018-04442-y.

3.

Structure, function and antagonism of semen amyloids.

Röcker A, Roan NR, Yadav JK, Fändrich M, Münch J.

Chem Commun (Camb). 2018 Jul 5;54(55):7557-7569. doi: 10.1039/c8cc01491d. Review.

PMID:
29873340
4.

Resident T cells stand up to HIV.

Roan NR.

Sci Immunol. 2018 Jun 1;3(24). pii: eaat6121. doi: 10.1126/sciimmunol.aat6121. Review.

PMID:
29858287
5.

Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma.

Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR.

Biol Reprod. 2018 Aug 1;99(2):336-348. doi: 10.1093/biolre/ioy056.

PMID:
29518187
6.

An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies.

Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S31-S39. doi: 10.1089/AID.2017.0208.

PMID:
28882052
7.

Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells.

Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR.

Cell Rep. 2017 Jul 25;20(4):984-998. doi: 10.1016/j.celrep.2017.06.087.

8.

Semen amyloids participate in spermatozoa selection and clearance.

Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC.

Elife. 2017 Jun 27;6. pii: e24888. doi: 10.7554/eLife.24888.

9.

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.

Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR.

PLoS Pathog. 2017 Feb 16;13(2):e1006163. doi: 10.1371/journal.ppat.1006163. eCollection 2017 Feb.

10.
11.

Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection.

LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI.

J Biol Chem. 2016 Jul 1;291(27):14045-55. doi: 10.1074/jbc.M116.718684. Epub 2016 May 11.

12.

Amyloid formation: functional friend or fearful foe?

Bergman P, Roan NR, Römling U, Bevins CL, Münch J.

J Intern Med. 2016 Aug;280(2):139-52. doi: 10.1111/joim.12479. Epub 2016 May 6. Review.

13.

Evaluation of EPI-X4 as a urinary peptide biomarker for diagnosis and prognosis of late acute GvHD.

Müller JA, Zirafi O, Roan NR, Lee SJ, Münch J.

Bone Marrow Transplant. 2016 Aug;51(8):1137-9. doi: 10.1038/bmt.2016.65. Epub 2016 Apr 4. No abstract available.

14.

Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.

Roan NR, Jakobsen MR.

Curr HIV/AIDS Rep. 2016 Feb;13(1):53-63. doi: 10.1007/s11904-016-0305-0. Review.

15.

Comparison of the effect of semen from HIV-infected and uninfected men on CD4+ T-cell infection.

Camus C, Matusali G, Bourry O, Mahe D, Aubry F, Bujan L, Pasquier C, Massip P, Ravel C, Zirafi O, Munch J, Roan NR, Pineau C, Dejucq-Rainsford N.

AIDS. 2016 May 15;30(8):1197-208. doi: 10.1097/QAD.0000000000001048.

16.

Improving preclinical models of HIV microbicide efficacy.

Roan NR, Münch J.

Trends Microbiol. 2015 Aug;23(8):445-7. doi: 10.1016/j.tim.2015.05.001.

17.

Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides.

Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J.

Sci Transl Med. 2014 Nov 12;6(262):262ra157. doi: 10.1126/scitranslmed.3009634.

18.

Structural characterization of semen coagulum-derived SEM1(86-107) amyloid fibrils that enhance HIV-1 infection.

French KC, Roan NR, Makhatadze GI.

Biochemistry. 2014 May 27;53(20):3267-77. doi: 10.1021/bi500427r. Epub 2014 May 12.

19.

Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection.

Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC.

J Virol. 2014 Jul;88(13):7221-34. doi: 10.1128/JVI.00269-14. Epub 2014 Apr 16.

20.

Interaction of fibronectin with semen amyloids synergistically enhances HIV infection.

Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC.

J Infect Dis. 2014 Oct 1;210(7):1062-6. doi: 10.1093/infdis/jiu220. Epub 2014 Apr 8.

21.

Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen.

Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J.

Nat Commun. 2014 Apr 1;5:3508. doi: 10.1038/ncomms4508.

22.

Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.

Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR.

Hum Reprod. 2014 Jun;29(6):1255-70. doi: 10.1093/humrep/deu047. Epub 2014 Mar 13.

23.

Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture.

Tang Q, Roan NR, Yamamura Y.

J Virol. 2013 Dec;87(23):12583-91. doi: 10.1128/JVI.02083-13. Epub 2013 Sep 11.

24.

Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses.

Yolamanova M, Meier C, Shaytan AK, Vas V, Bertoncini CW, Arnold F, Zirafi O, Usmani SM, Müller JA, Sauter D, Goffinet C, Palesch D, Walther P, Roan NR, Geiger H, Lunov O, Simmet T, Bohne J, Schrezenmeier H, Schwarz K, Ständker L, Forssmann WG, Salvatella X, Khalatur PG, Khokhlov AR, Knowles TP, Weil T, Kirchhoff F, Münch J.

Nat Nanotechnol. 2013 Feb;8(2):130-6. doi: 10.1038/nnano.2012.248. Epub 2013 Jan 20.

PMID:
23334171
25.

[Role of semen-derived amyloid fibrils as facilitators of HIV infection].

Roan NR, Cavrois M, Greene WC.

Med Sci (Paris). 2012 Apr;28(4):358-60. doi: 10.1051/medsci/2012284008. Epub 2012 Apr 25. French. No abstract available.

26.

Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.

Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC.

Cell Host Microbe. 2011 Dec 15;10(6):541-50. doi: 10.1016/j.chom.2011.10.010.

27.

Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection.

Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J.

J Virol. 2012 Jan;86(2):1244-9. doi: 10.1128/JVI.06121-11. Epub 2011 Nov 16.

28.

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.

Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J.

Retrovirology. 2010 Jun 23;7:55. doi: 10.1186/1742-4690-7-55.

29.

Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).

Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC.

J Biol Chem. 2010 Jan 15;285(3):1861-9. doi: 10.1074/jbc.M109.066167. Epub 2009 Nov 6.

30.

T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis.

Gondek DC, Roan NR, Starnbach MN.

J Immunol. 2009 Jul 15;183(2):1313-9. doi: 10.4049/jimmunol.0900295. Epub 2009 Jun 26.

31.

The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection.

Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC.

J Virol. 2009 Jan;83(1):73-80. doi: 10.1128/JVI.01366-08. Epub 2008 Oct 22.

32.

Conquering sexually transmitted diseases.

Starnbach MN, Roan NR.

Nat Rev Immunol. 2008 Apr;8(4):313-7. doi: 10.1038/nri2272. Epub 2008 Feb 29. Review.

PMID:
18309315
33.

Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers.

Grotenbreg GM, Roan NR, Guillen E, Meijers R, Wang JH, Bell GW, Starnbach MN, Ploegh HL.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3831-6. doi: 10.1073/pnas.0711504105. Epub 2008 Feb 1.

34.

A seminal finding for understanding HIV transmission.

Roan NR, Greene WC.

Cell. 2007 Dec 14;131(6):1044-6.

35.

Immune-mediated control of Chlamydia infection.

Roan NR, Starnbach MN.

Cell Microbiol. 2008 Jan;10(1):9-19. Epub 2007 Nov 2. Review.

PMID:
17979983
36.
37.

Monitoring the T cell response to genital tract infection.

Roan NR, Gierahn TM, Higgins DE, Starnbach MN.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12069-74. Epub 2006 Jul 31.

38.

Developmental regulation of Chlamydia trachomatis class I accessible protein-1, a CD8+ T cell antigen.

Balsara ZR, Roan NR, Steele LN, Starnbach MN.

J Infect Dis. 2006 May 15;193(10):1459-63. Epub 2006 Apr 12.

PMID:
16619195
39.
40.

The Listeria monocytogenes lemA gene product is not required for intracellular infection or to activate fMIGWII-specific T cells.

D'Orazio SE, Velasquez M, Roan NR, Naveiras-Torres O, Starnbach MN.

Infect Immun. 2003 Dec;71(12):6721-7.

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