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Sphingosine-1-phosphate analog FTY720 reverses obesity but not age-induced anabolic resistance to muscle contraction.

Rivas DA, Rice NP, Ezzyat Y, McDonald DJ, Cooper BE, Fielding RA.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C502-C512. doi: 10.1152/ajpcell.00455.2018. Epub 2019 Jun 26.


JNK regulates muscle remodeling via myostatin/SMAD inhibition.

Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ.

Nat Commun. 2018 Aug 2;9(1):3030. doi: 10.1038/s41467-018-05439-3.


Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle With Aging.

Margolis LM, Rivas DA.

Exerc Sport Sci Rev. 2018 Apr;46(2):86-91. doi: 10.1249/JES.0000000000000147. Review.


Effects of Potassium Bicarbonate Supplements on Circulating microRNA Expression.

Margolis LM, Dawson-Hughes B, Rivas DA, Ezzyat Y, Fielding RA, Ceglia L.

J Endocr Soc. 2017 Jun 14;1(8):1015-1026. doi: 10.1210/js.2017-00106. eCollection 2017 Aug 1.


Upregulation of circulating myomiR following short-term energy restriction is inversely associated with whole body protein synthesis.

Margolis LM, Rivas DA, Pasiakos SM, McClung JP, Ceglia L, Fielding RA.

Am J Physiol Regul Integr Comp Physiol. 2017 Sep 1;313(3):R298-R304. doi: 10.1152/ajpregu.00054.2017. Epub 2017 Jun 28.


Circulating MicroRNA Are Predictive of Aging and Acute Adaptive Response to Resistance Exercise in Men.

Margolis LM, Lessard SJ, Ezzyat Y, Fielding RA, Rivas DA.

J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1319-1326. doi: 10.1093/gerona/glw243.


Prolonged Calorie Restriction Downregulates Skeletal Muscle mTORC1 Signaling Independent of Dietary Protein Intake and Associated microRNA Expression.

Margolis LM, Rivas DA, Berrone M, Ezzyat Y, Young AJ, McClung JP, Fielding RA, Pasiakos SM.

Front Physiol. 2016 Oct 5;7:445. eCollection 2016.


Calorie Restricted High Protein Diets Downregulate Lipogenesis and Lower Intrahepatic Triglyceride Concentrations in Male Rats.

Margolis LM, Rivas DA, Ezzyat Y, Gaffney-Stomberg E, Young AJ, McClung JP, Fielding RA, Pasiakos SM.

Nutrients. 2016 Sep 15;8(9). pii: E571. doi: 10.3390/nu8090571.


Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity.

Rivas DA, McDonald DJ, Rice NP, Haran PH, Dolnikowski GG, Fielding RA.

Am J Physiol Regul Integr Comp Physiol. 2016 Apr 1;310(7):R561-9. doi: 10.1152/ajpregu.00198.2015. Epub 2016 Jan 13.


The AMPK-related kinase SNARK regulates muscle mass and myocyte survival.

Lessard SJ, Rivas DA, So K, Koh HJ, Queiroz AL, Hirshman MF, Fielding RA, Goodyear LJ.

J Clin Invest. 2016 Feb;126(2):560-70.


Implications of exercise training and distribution of protein intake on molecular processes regulating skeletal muscle plasticity.

Margolis LM, Rivas DA.

Calcif Tissue Int. 2015 Mar;96(3):211-21. doi: 10.1007/s00223-014-9921-0. Epub 2014 Oct 28. Review.


Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF-1 signaling.

Rivas DA, Lessard SJ, Rice NP, Lustgarten MS, So K, Goodyear LJ, Parnell LD, Fielding RA.

FASEB J. 2014 Sep;28(9):4133-47. doi: 10.1096/fj.14-254490. Epub 2014 Jun 13.


A randomized study on the effect of vitamin D₃ supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women.

Ceglia L, Niramitmahapanya S, da Silva Morais M, Rivas DA, Harris SS, Bischoff-Ferrari H, Fielding RA, Dawson-Hughes B.

J Clin Endocrinol Metab. 2013 Dec;98(12):E1927-35. doi: 10.1210/jc.2013-2820. Epub 2013 Oct 9.


Efficacy and safety of dapoxetine in men with premature ejaculation and concomitant erectile dysfunction treated with a phosphodiesterase type 5 inhibitor: randomized, placebo-controlled, phase III study.

McMahon CG, Giuliano F, Dean J, Hellstrom WJ, Bull S, Tesfaye F, Sharma O, Rivas DA, Aquilina JW.

J Sex Med. 2013 Sep;10(9):2312-25. doi: 10.1111/jsm.12236. Epub 2013 Jul 11.


Exercise training enhances white adipose tissue metabolism in rats selectively bred for low- or high-endurance running capacity.

Stephenson EJ, Lessard SJ, Rivas DA, Watt MJ, Yaspelkis BB 3rd, Koch LG, Britton SL, Hawley JA.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E429-38. doi: 10.1152/ajpendo.00544.2012. Epub 2013 Jun 11.


Effects of alkali supplementation and vitamin D insufficiency on rat skeletal muscle.

Ceglia L, Rivas DA, Pojednic RM, Price LL, Harris SS, Smith D, Fielding RA, Dawson-Hughes B.

Endocrine. 2013 Oct;44(2):454-64. doi: 10.1007/s12020-013-9976-0. Epub 2013 May 11.


Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks.

Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL, Qi NR, Gustafsson T, Fielding RA, Timmons JA, Britton SL, Koch LG, Goodyear LJ.

Diabetes. 2013 Aug;62(8):2717-27. doi: 10.2337/db13-0062. Epub 2013 Apr 22.


Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function.

Ritchie RH, Leo CH, Qin C, Stephenson EJ, Bowden MA, Buxton KD, Lessard SJ, Rivas DA, Koch LG, Britton SL, Hawley JA, Woodman OL.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H729-39. doi: 10.1152/ajpheart.00638.2012. Epub 2012 Dec 21.


Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males.

Rivas DA, Morris EP, Haran PH, Pasha EP, Morais Mda S, Dolnikowski GG, Phillips EM, Fielding RA.

J Appl Physiol (1985). 2012 Dec 1;113(11):1727-36. doi: 10.1152/japplphysiol.00412.2012. Epub 2012 Oct 4.


Role and potential mechanisms of anabolic resistance in sarcopenia.

Haran PH, Rivas DA, Fielding RA.

J Cachexia Sarcopenia Muscle. 2012 Sep;3(3):157-62. doi: 10.1007/s13539-012-0068-4. Epub 2012 May 16.


Lipogenic regulators are elevated with age and chronic overload in rat skeletal muscle.

Rivas DA, Morris EP, Fielding RA.

Acta Physiol (Oxf). 2011 Aug;202(4):691-701. doi: 10.1111/j.1748-1716.2011.02289.x. Epub 2011 Apr 22.


Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle.

Rivas DA, Lessard SJ, Saito M, Friedhuber AM, Koch LG, Britton SL, Yaspelkis BB 3rd, Hawley JA.

Am J Physiol Regul Integr Comp Physiol. 2011 Apr;300(4):R835-43. doi: 10.1152/ajpregu.00659.2010. Epub 2011 Jan 26.


Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials.

McMahon CG, Althof SE, Kaufman JM, Buvat J, Levine SB, Aquilina JW, Tesfaye F, Rothman M, Rivas DA, Porst H.

J Sex Med. 2011 Feb;8(2):524-39. doi: 10.1111/j.1743-6109.2010.02097.x. Epub 2010 Nov 8.


Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity.

Lessard SJ, Rivas DA, Stephenson EJ, Yaspelkis BB 3rd, Koch LG, Britton SL, Hawley JA.

Am J Physiol Regul Integr Comp Physiol. 2011 Jan;300(1):R175-82. doi: 10.1152/ajpregu.00338.2010. Epub 2010 Nov 3.


Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle.

Yaspelkis BB 3rd, Kvasha IA, Lessard SJ, Rivas DA, Hawley JA.

Eur J Appl Physiol. 2010 Nov;110(4):779-88. doi: 10.1007/s00421-010-1559-7. Epub 2010 Jul 2.


Baseline characteristics and treatment outcomes for men with acquired or lifelong premature ejaculation with mild or no erectile dysfunction: integrated analyses of two phase 3 dapoxetine trials.

Porst H, McMahon CG, Althof SE, Sharlip I, Bull S, Aquilina JW, Tesfaye F, Rivas DA.

J Sex Med. 2010 Jun;7(6):2231-2242. doi: 10.1111/j.1743-6109.2010.01820.x. Epub 2010 Apr 19.


mTOR function in skeletal muscle: a focal point for overnutrition and exercise.

Rivas DA, Lessard SJ, Coffey VG.

Appl Physiol Nutr Metab. 2009 Oct;34(5):807-16. doi: 10.1139/H09-073. Review.


Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity.

Lessard SJ, Rivas DA, Chen ZP, van Denderen BJ, Watt MJ, Koch LG, Britton SL, Kemp BE, Hawley JA.

Endocrinology. 2009 Nov;150(11):4883-91. doi: 10.1210/en.2009-0158. Epub 2009 Oct 9.


Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside.

Rivas DA, Yaspelkis BB 3rd, Hawley JA, Lessard SJ.

J Endocrinol. 2009 Sep;202(3):441-51. doi: 10.1677/JOE-09-0202. Epub 2009 Jul 2.


Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase 3 trial in 22 countries.

Buvat J, Tesfaye F, Rothman M, Rivas DA, Giuliano F.

Eur Urol. 2009 Apr;55(4):957-67. doi: 10.1016/j.eururo.2009.01.025. Epub 2009 Jan 21.


Glycogen storage and muscle glucose transporters (GLUT-4) of mice selectively bred for high voluntary wheel running.

Gomes FR, Rezende EL, Malisch JL, Lee SK, Rivas DA, Kelly SA, Lytle C, Yaspelkis BB 3rd, Garland T Jr.

J Exp Biol. 2009 Jan;212(Pt 2):238-48. doi: 10.1242/jeb.025296.


Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans.

Yeo WK, Lessard SJ, Chen ZP, Garnham AP, Burke LM, Rivas DA, Kemp BE, Hawley JA.

J Appl Physiol (1985). 2008 Nov;105(5):1519-26. doi: 10.1152/japplphysiol.90540.2008. Epub 2008 Sep 18.


Activation of atypical protein kinase Czeta toward TC10 is regulated by high-fat diet and aerobic exercise in skeletal muscle.

Saito M, Lessard SJ, Rivas DA, Reeder DW, Hawley JA, Yaspelkis BB 3rd.

Metabolism. 2008 Sep;57(9):1173-80. doi: 10.1016/j.metabol.2008.03.023.


Exercise reverses high-fat diet-induced impairments on compartmentalization and activation of components of the insulin-signaling cascade in skeletal muscle.

Yaspelkis BB 3rd, Lessard SJ, Reeder DW, Limon JJ, Saito M, Rivas DA, Kvasha I, Hawley JA.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E941-9. Epub 2007 Jul 10.


Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance.

Lessard SJ, Rivas DA, Chen ZP, Bonen A, Febbraio MA, Reeder DW, Kemp BE, Yaspelkis BB 3rd, Hawley JA.

Diabetes. 2007 Jul;56(7):1856-64. Epub 2007 Apr 17.


High-fat feeding effects on components of the CAP/Cbl signaling cascade in Sprague-Dawley rat skeletal muscle.

Bernard JR, Reeder DW, Herr HJ, Rivas DA, Yaspelkis BB 3rd.

Metabolism. 2006 Feb;55(2):203-12.


Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.

Herr HJ, Bernard JR, Reeder DW, Rivas DA, Limon JJ, Yaspelkis BB 3rd.

J Physiol. 2005 Jun 1;565(Pt 2):627-36. Epub 2005 Mar 31.


Chronic aerobic exercise enhances components of the classical and novel insulin signalling cascades in Sprague-Dawley rat skeletal muscle.

Bernard JR, Crain AM, Rivas DA, Herr HJ, Reeder DW, Yaspelkis BB 3rd.

Acta Physiol Scand. 2005 Apr;183(4):357-66.


Intravesical resiniferatoxin for refractory detrusor hyperreflexia: a multicenter, blinded, randomized, placebo-controlled trial.

Kim JH, Rivas DA, Shenot PJ, Green B, Kennelly M, Erickson JR, O'Leary M, Yoshimura N, Chancellor MB.

J Spinal Cord Med. 2003 Winter;26(4):358-63.


The management of neurogenic bladder and sexual dysfunction after spinal cord injury.

Burns AS, Rivas DA, Ditunno JF.

Spine (Phila Pa 1976). 2001 Dec 15;26(24 Suppl):S129-36. Review.


Long-term effectiveness of sacral nerve stimulation for refractory urge incontinence.

Janknegt RA, Hassouna MM, Siegel SW, Schmidt RA, Gajewski JB, Rivas DA, Elhilali MM, Milam DC, van Kerrebroeck PE, Dijkema HE, Lycklama à Nÿeholt AA, Fall M, Jonas U, Catanzaro F, Fowler CJ, Oleson KA.

Eur Urol. 2001 Jan;39(1):101-6.


Transurethral microwave thermotherapy of the prostate without intravenous sedation: results of a single United States center using both low- and high-energy protocols. TJUH TUMT Study Group.

Rivas DA, Bagley D, Gomella LG, Hirsch IH, Hubert C, Lombardo S, McGinnis DE, Mulholland SG, Shenot PJ, Strup SE, Vasavada SP.

Tech Urol. 2000 Dec;6(4):282-7.


Intravesical capsaicin therapy: a review.

Ozawa H, Jung SY, Fraser MO, Rivas DA, Chancellor MB.

J Spinal Cord Med. 1999 Summer;22(2):114-8. Review. No abstract available.


Sacral neuromodulation in the treatment of urgency-frequency symptoms: a multicenter study on efficacy and safety.

Hassouna MM, Siegel SW, Nÿeholt AA, Elhilali MM, van Kerrebroeck PE, Das AK, Gajewski JB, Janknegt RA, Rivas DA, Dijkema H, Milam DF, Oleson KA, Schmidt RA.

J Urol. 2000 Jun;163(6):1849-54.


Removal of UroLume endoprosthesis: experience of the North American Study Group for detrusor-sphincter dyssynergia application.

Gajewski JB, Chancellor MB, Ackman CF, Appell RA, Bennett J, Binard J, Boone TB, Chetner MP, Crewalk JA, Defalco A, Foote J, Green B, Juma S, Jung SY, Linsenmeyer TA, Macaluso JN Jr, Macmillan R, Mayo M, Ozawa H, Roehrborn CG, Schmidt J, Shenot PJ, Stone A, Vazquez A, Killorin W, Rivas DA.

J Urol. 2000 Mar;163(3):773-6.


Beneficial effect of intranasal desmopressin for men with benign prostatic hyperplasia and nocturia: preliminary results.

Chancellor MB, Atan A, Rivas DA, Watanabe T, Tai HL, Kumon H.

Tech Urol. 1999 Dec;5(4):191-4.


Sphincteric stent versus external sphincterotomy in spinal cord injured men: prospective randomized multicenter trial.

Chancellor MB, Bennett C, Simoneau AR, Finocchiaro MV, Kline C, Bennett JK, Foote JE, Green BG, Martin SH, Killoran RW, Crewalk JA, Rivas DA.

J Urol. 1999 Jun;161(6):1893-8.


Long-term followup of the North American multicenter UroLume trial for the treatment of external detrusor-sphincter dyssynergia.

Chancellor MB, Gajewski J, Ackman CF, Appell RA, Bennett J, Binard J, Boone TB, Chetner MP, Crewalk JA, Defalco A, Foote J, Green B, Juma S, Jung SY, Linsenmeyer TA, MacMillan R, Mayo M, Ozawa H, Roehrborn CG, Shenot PJ, Stone A, Vazquez A, Killorin W, Rivas DA.

J Urol. 1999 May;161(5):1545-50.


Spermatogenesis in early and chronic phases of experimental spinal cord injury in the rodent model.

Hirsch IH, Huang B, Chancellor MB, Rivas DA, Salzman SK, Jost LK, Evenson DP.

J Androl. 1999 Jan-Feb;20(1):63-71.

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