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Items: 1 to 50 of 86

1.

Formation of HETE-EAs and dihydroxy derivatives in mouse kidney tissue and analysis by high-performance liquid chromatography tandem mass spectrometry.

Dempsey SK, Gesseck AM, Ahmad A, Daneva Z, Ritter JK, Poklis JL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Sep 15;1126-1127:121748. doi: 10.1016/j.jchromb.2019.121748. Epub 2019 Aug 6.

PMID:
31437772
2.

Knockout of Sphingosine Kinase 1 Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction Model.

Zhang X, Wang W, Ji XY, Ritter JK, Li N.

Am J Nephrol. 2019;50(3):196-203. doi: 10.1159/000502448. Epub 2019 Aug 15.

PMID:
31416077
3.

Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes.

Hong J, Bhat OM, Li G, Dempsey SK, Zhang Q, Ritter JK, Li W, Li PL.

Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):849-860. doi: 10.1016/j.bbamcr.2019.02.007. Epub 2019 Feb 14.

4.

Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor.

Daneva Z, Dempsey SK, Ahmad A, Li N, Li PL, Ritter JK.

J Pharmacol Exp Ther. 2019 Feb;368(2):187-198. doi: 10.1124/jpet.118.252320. Epub 2018 Dec 7.

PMID:
30530623
5.

Role of Nitric Oxide in the Cardiovascular and Renal Systems.

Ahmad A, Dempsey SK, Daneva Z, Azam M, Li N, Li PL, Ritter JK.

Int J Mol Sci. 2018 Sep 3;19(9). pii: E2605. doi: 10.3390/ijms19092605. Review.

6.

Inhibition of pannexin-1 channel activity by adiponectin in podocytes: Role of acid ceramidase activation.

Li G, Zhang Q, Hong J, Ritter JK, Li PL.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1246-1256. doi: 10.1016/j.bbalip.2018.07.016. Epub 2018 Aug 1.

7.

Modulation of mean arterial pressure and diuresis by renomedullary infusion of a selective inhibitor of fatty acid amide hydrolase.

Ahmad A, Dempsey SK, Daneva Z, Li N, Poklis JL, Li PL, Ritter JK.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F967-F976. doi: 10.1152/ajprenal.00090.2018. Epub 2018 May 30.

8.

Sphingosine-1-phosphate pathway in renal fibrosis.

Zhang X, Ritter JK, Li N.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F752-F756. doi: 10.1152/ajprenal.00596.2017. Epub 2018 Apr 4. Review.

9.

Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of fatty acid amide hydrolase and monoacylglycerol lipase.

Ahmad A, Daneva Z, Li G, Dempsey SK, Li N, Poklis JL, Lichtman A, Li PL, Ritter JK.

Am J Physiol Renal Physiol. 2017 Nov 1;313(5):F1068-F1076. doi: 10.1152/ajprenal.00196.2017. Epub 2017 Aug 2.

10.

NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury.

Li G, Chen Z, Bhat OM, Zhang Q, Abais-Battad JM, Conley SM, Ritter JK, Li PL.

J Lipid Res. 2017 Jun;58(6):1080-1090. doi: 10.1194/jlr.M072587. Epub 2017 Apr 12.

11.

Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes.

Li G, Xia M, Abais JM, Boini K, Li PL, Ritter JK.

J Pharmacol Exp Ther. 2016 Jul;358(1):61-70. doi: 10.1124/jpet.116.233239. Epub 2016 May 11.

12.

Anandamide and its metabolites: what are their roles in the kidney?

Ritter JK, Li G, Xia M, Boini K.

Front Biosci (Schol Ed). 2016 Jun 1;8:264-77. Review.

13.

Identification of Metabolite Biomarkers of the Designer Hallucinogen 25I-NBOMe in Mouse Hepatic Microsomal Preparations and Human Urine Samples Associated with Clinical Intoxication.

Poklis JL, Dempsey SK, Liu K, Ritter JK, Wolf C, Zhang S, Poklis A.

J Anal Toxicol. 2015 Oct;39(8):607-16. doi: 10.1093/jat/bkv079.

14.

Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: role of p62/Sequestosome 1 as a signaling hub.

Li G, Li CX, Xia M, Ritter JK, Gehr TW, Boini K, Li PL.

Cell Physiol Biochem. 2015;35(5):1773-86. doi: 10.1159/000373989. Epub 2015 Mar 26.

15.

Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases.

Li PL, Zhang Y, Abais JM, Ritter JK, Zhang F.

Messenger (Los Angel). 2013 Jun 1;2(2):63-85.

16.

Upregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: role of NADPH oxidase.

Wang M, Abais JM, Meng N, Zhang Y, Ritter JK, Li PL, Tang WX.

Free Radic Biol Med. 2014 Jun;71:109-20. doi: 10.1016/j.freeradbiomed.2014.03.015. Epub 2014 Mar 19.

17.

Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes.

Xiong J, Xia M, Xu M, Zhang Y, Abais JM, Li G, Riebling CR, Ritter JK, Boini KM, Li PL.

J Cell Mol Med. 2013 Dec;17(12):1598-607. doi: 10.1111/jcmm.12173. Epub 2013 Nov 17.

18.

Contribution of NADPH oxidase to membrane CD38 internalization and activation in coronary arterial myocytes.

Xu M, Li XX, Ritter JK, Abais JM, Zhang Y, Li PL.

PLoS One. 2013 Aug 7;8(8):e71212. doi: 10.1371/journal.pone.0071212. Print 2013.

19.

Contribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice.

Ritter JK, Fang Y, Xia M, Li PL, Dewey WL.

Neuroreport. 2012 Sep 12;23(13):780-5. doi: 10.1097/WNR.0b013e3283571757.

20.

Production and actions of the anandamide metabolite prostamide E2 in the renal medulla.

Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL.

J Pharmacol Exp Ther. 2012 Sep;342(3):770-9. doi: 10.1124/jpet.112.196451. Epub 2012 Jun 8.

21.

ABH gel is not absorbed from the skin of normal volunteers.

Smith TJ, Ritter JK, Poklis JL, Fletcher D, Coyne PJ, Dodson P, Parker G.

J Pain Symptom Manage. 2012 May;43(5):961-6. doi: 10.1016/j.jpainsymman.2011.05.017.

PMID:
22560361
22.

Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells.

Xu M, Xia M, Li XX, Han WQ, Boini KM, Zhang F, Zhang Y, Ritter JK, Li PL.

Mol Biol Cell. 2012 Apr;23(8):1546-57. doi: 10.1091/mbc.E11-09-0821. Epub 2012 Feb 22.

23.

Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells.

Han WQ, Xia M, Xu M, Boini KM, Ritter JK, Li NJ, Li PL.

J Cell Sci. 2012 Mar 1;125(Pt 5):1225-34. doi: 10.1242/jcs.094565. Epub 2012 Feb 20.

24.

Linking empirical estimates of body burden of environmental chemicals and wellness using NHANES data.

Gennings C, Ellis R, Ritter JK.

Environ Int. 2012 Feb;39(1):56-65. doi: 10.1016/j.envint.2011.09.002. Epub 2011 Nov 1.

25.

NAD(P)H oxidase-dependent intracellular and extracellular O2•- production in coronary arterial myocytes from CD38 knockout mice.

Xu M, Zhang Y, Xia M, Li XX, Ritter JK, Zhang F, Li PL.

Free Radic Biol Med. 2012 Jan 15;52(2):357-65. doi: 10.1016/j.freeradbiomed.2011.10.485. Epub 2011 Nov 3.

26.

Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.

Harbourt DE, Fallon JK, Ito S, Baba T, Ritter JK, Glish GL, Smith PC.

Anal Chem. 2012 Jan 3;84(1):98-105. doi: 10.1021/ac201704a. Epub 2011 Dec 5.

27.

Absolute quantification of human uridine-diphosphate glucuronosyl transferase (UGT) enzyme isoforms 1A1 and 1A6 by tandem LC-MS.

Fallon JK, Harbourt DE, Maleki SH, Kessler FK, Ritter JK, Smith PC.

Drug Metab Lett. 2008 Aug;2(3):210-22.

PMID:
19356096
28.

Androgen regulation of renal uridine diphosphoglucuronosyltransferase 1A1 in rats.

Stern ST, Tallman MN, Miles KK, Ritter JK, Smith PC.

Drug Metab Dispos. 2008 Sep;36(9):1737-9. doi: 10.1124/dmd.108.020610. Epub 2008 May 30.

PMID:
18515331
29.

Regulation of the rat UGT1A6 by glucocorticoids involves a cryptic glucocorticoid response element.

Falkner KC, Ritter JK, Prough RA.

Drug Metab Dispos. 2008 Feb;36(2):409-17. Epub 2007 Nov 26.

30.

Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia.

Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL.

J Pharmacol Exp Ther. 2007 Jul;322(1):186-94. Epub 2007 Apr 3.

PMID:
17405869
31.

Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics.

Ritter JK.

Expert Opin Drug Metab Toxicol. 2007 Feb;3(1):93-107. Review.

PMID:
17269897
32.

Gender-related differences in mycophenolate mofetil-induced gastrointestinal toxicity in rats.

Stern ST, Tallman MN, Miles KK, Ritter JK, Dupuis RE, Smith PC.

Drug Metab Dispos. 2007 Mar;35(3):449-54. Epub 2006 Dec 15.

PMID:
17172313
33.

Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation.

Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH.

Drug Metab Dispos. 2007 Mar;35(3):419-27. Epub 2006 Dec 6.

PMID:
17151188
34.

The contribution of intestinal UDP-glucuronosyltransferases in modulating 7-ethyl-10-hydroxy-camptothecin (SN-38)-induced gastrointestinal toxicity in rats.

Tallman MN, Miles KK, Kessler FK, Nielsen JN, Tian X, Ritter JK, Smith PC.

J Pharmacol Exp Ther. 2007 Jan;320(1):29-37. Epub 2006 Sep 26.

PMID:
17003228
35.

Characterization of rat intestinal microsomal UDP-glucuronosyltransferase activity toward mycophenolic acid.

Miles KK, Kessler FK, Smith PC, Ritter JK.

Drug Metab Dispos. 2006 Sep;34(9):1632-9. Epub 2006 Jun 21.

PMID:
16790558
36.

Adenovirus-mediated gene therapy to restore expression and functionality of multiple UDP-glucuronosyltransferase 1A enzymes in Gunn rat liver.

Miles KK, Kessler FK, Webb LJ, Smith PC, Ritter JK.

J Pharmacol Exp Ther. 2006 Sep;318(3):1240-7. Epub 2006 Jun 8.

PMID:
16763095
37.

Activity of rat UGT1A1 towards benzo[a]pyrene phenols and dihydrodiols.

Webb L, Miles K, Kessler F, Ritter JK.

Environ Toxicol Pharmacol. 2006 May;21(3):224-30. doi: 10.1016/j.etap.2005.07.018. Epub 2005 Nov 2.

PMID:
21783661
38.

Effect of chronic renal insufficiency on hepatic and renal udp-glucuronyltransferases in rats.

Yu C, Ritter JK, Krieg RJ, Rege B, Karnes TH, Sarkar MA.

Drug Metab Dispos. 2006 Apr;34(4):621-7. Epub 2006 Jan 13.

PMID:
16415115
39.

Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.

Chen S, Beaton D, Nguyen N, Senekeo-Effenberger K, Brace-Sinnokrak E, Argikar U, Remmel RP, Trottier J, Barbier O, Ritter JK, Tukey RH.

J Biol Chem. 2005 Nov 11;280(45):37547-57. Epub 2005 Sep 9.

40.

An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity.

Miles KK, Stern ST, Smith PC, Kessler FK, Ali S, Ritter JK.

Drug Metab Dispos. 2005 Oct;33(10):1513-20. Epub 2005 Jul 20.

PMID:
16033946
42.

Optimization of conditions for clinical human hepatocyte infusion.

Fisher RA, Bu D, Thompson M, Wolfe L, Ritter JK.

Cell Transplant. 2004;13(6):677-89.

PMID:
15648738
43.

Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.

Webb LJ, Miles KK, Auyeung DJ, Kessler FK, Ritter JK.

Drug Metab Dispos. 2005 Jan;33(1):77-82. Epub 2004 Oct 22.

PMID:
15502008
44.

Glucuronidation and the UDP-glucuronosyltransferases in health and disease.

Wells PG, Mackenzie PI, Chowdhury JR, Guillemette C, Gregory PA, Ishii Y, Hansen AJ, Kessler FK, Kim PM, Chowdhury NR, Ritter JK.

Drug Metab Dispos. 2004 Mar;32(3):281-90. Review.

PMID:
14977861
45.

Differential regulation of alternate UDP-glucuronosyltransferase 1A6 gene promoters by hepatic nuclear factor-1.

Auyeung DJ, Kessler FK, Ritter JK.

Toxicol Appl Pharmacol. 2003 Sep 1;191(2):156-66.

PMID:
12946651
46.
47.

Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases.

Kessler FK, Kessler MR, Auyeung DJ, Ritter JK.

Drug Metab Dispos. 2002 Mar;30(3):324-30.

PMID:
11854153
48.

An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.

Auyeung DJ, Kessler FK, Ritter JK.

Toxicol Appl Pharmacol. 2001 Jul 1;174(1):60-8.

PMID:
11437649
49.

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions.

Ritter JK.

Chem Biol Interact. 2000 Dec 1;129(1-2):171-93. Review.

PMID:
11154740
50.

Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene.

Guillemette C, Ritter JK, Auyeung DJ, Kessler FK, Housman DE.

Pharmacogenetics. 2000 Oct;10(7):629-44.

PMID:
11037804

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