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Items: 20

1.

Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling.

Terrell EM, Durrant DE, Ritt DA, Sealover NE, Sheffels E, Spencer-Smith R, Esposito D, Zhou Y, Hancock JF, Kortum RL, Morrison DK.

Mol Cell. 2019 Oct 3. pii: S1097-2765(19)30689-6. doi: 10.1016/j.molcel.2019.09.004. [Epub ahead of print]

PMID:
31606273
2.

Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.

Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, Ritt DA, Semler E, Specht S, Stauffer J, Morrison DK, Lorentzen E, Westlake CJ.

Dev Cell. 2019 Jul 22;50(2):229-246.e7. doi: 10.1016/j.devcel.2019.05.022. Epub 2019 Jun 13.

PMID:
31204173
3.

M-Ras/Shoc2 signaling modulates E-cadherin turnover and cell-cell adhesion during collective cell migration.

Kota P, Terrell EM, Ritt DA, Insinna C, Westlake CJ, Morrison DK.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3536-3545. doi: 10.1073/pnas.1805919116. Epub 2019 Feb 11.

4.

Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling.

Valdeira ASC, Ritt DA, Morrison DK, McMahon JB, Gustafson KR, Salvador JAR.

Front Chem. 2018 Sep 28;6:434. doi: 10.3389/fchem.2018.00434. eCollection 2018.

5.

Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling.

Yan P, Ritt DA, Zlotkowski K, Bokesch HR, Reinhold WC, Schneekloth JS Jr, Morrison DK, Gustafson KR.

J Nat Prod. 2018 Jul 27;81(7):1666-1672. doi: 10.1021/acs.jnatprod.8b00343. Epub 2018 Jul 6.

6.

Survival of BRCA2-Deficient Cells Is Promoted by GIPC3, a Novel Genetic Interactor of BRCA2.

Ding X, Philip S, Martin BK, Pang Y, Burkett S, Swing DA, Pamala C, Ritt DA, Zhou M, Morrison DK, Ji X, Sharan SK.

Genetics. 2017 Dec;207(4):1335-1345. doi: 10.1534/genetics.117.300357. Epub 2017 Oct 11.

7.

Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.

Ritt DA, Abreu-Blanco MT, Bindu L, Durrant DE, Zhou M, Specht SI, Stephen AG, Holderfield M, Morrison DK.

Mol Cell. 2016 Dec 1;64(5):875-887. doi: 10.1016/j.molcel.2016.10.029. Epub 2016 Nov 23.

8.
9.

The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons.

Lim J, Ritt DA, Zhou M, Morrison DK.

Curr Biol. 2014 Mar 31;24(7):786-92. doi: 10.1016/j.cub.2014.02.036. Epub 2014 Mar 20.

10.

The importance of Raf dimerization in cell signaling.

Freeman AK, Ritt DA, Morrison DK.

Small GTPases. 2013 Jul-Sep;4(3):180-5. doi: 10.4161/sgtp.26117. Epub 2013 Aug 28.

11.

Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling.

Freeman AK, Ritt DA, Morrison DK.

Mol Cell. 2013 Feb 21;49(4):751-8. doi: 10.1016/j.molcel.2012.12.018. Epub 2013 Jan 24.

12.

RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling.

McKay MM, Ritt DA, Morrison DK.

Curr Biol. 2011 Apr 12;21(7):563-8. doi: 10.1016/j.cub.2011.02.033. Epub 2011 Mar 31.

13.

CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.

Wang J, Sarkar TR, Zhou M, Sharan S, Ritt DA, Veenstra TD, Morrison DK, Huang AM, Sterneck E.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16131-6. doi: 10.1073/pnas.1002603107. Epub 2010 Aug 30.

14.

Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling.

Ritt DA, Monson DM, Specht SI, Morrison DK.

Mol Cell Biol. 2010 Feb;30(3):806-19. doi: 10.1128/MCB.00569-09. Epub 2009 Nov 23.

15.

KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.

Dougherty MK, Ritt DA, Zhou M, Specht SI, Monson DM, Veenstra TD, Morrison DK.

Mol Cell. 2009 Jun 26;34(6):652-62. doi: 10.1016/j.molcel.2009.06.001.

16.

Signaling dynamics of the KSR1 scaffold complex.

McKay MM, Ritt DA, Morrison DK.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11022-7. doi: 10.1073/pnas.0901590106. Epub 2009 Jun 18.

17.

CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation.

Ritt DA, Zhou M, Conrads TP, Veenstra TD, Copeland TD, Morrison DK.

Curr Biol. 2007 Jan 23;17(2):179-84. Epub 2006 Dec 14.

18.

KSR regulation of the Raf-MEK-ERK cascade.

Ritt DA, Daar IO, Morrison DK.

Methods Enzymol. 2006;407:224-37.

PMID:
16757327
19.

Regulation of Raf-1 by direct feedback phosphorylation.

Dougherty MK, Müller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK.

Mol Cell. 2005 Jan 21;17(2):215-24.

20.

Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate.

Müller J, Ritt DA, Copeland TD, Morrison DK.

EMBO J. 2003 Sep 1;22(17):4431-42.

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