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Exploring the "Latin American Mediterranean" family and the RDRio lineage in Mycobacterium tuberculosis isolates from Paraguay, Argentina and Venezuela.

Díaz Acosta CC, Russomando G, Candia N, Ritacco V, Vasconcellos SEG, de Berrêdo Pinho Moreira M, de Romero NJ, Morcillo N, De Waard JH, Gomes HM, Suffys PN.

BMC Microbiol. 2019 Jun 13;19(1):131. doi: 10.1186/s12866-019-1479-6.


Survival of an epidemic MDR strain of Mycobacterium tuberculosis and its non-prosperous variant within activated macrophages.

Yokobori N, Monteserin J, Rearte B, Paul R, Símboli N, López B, Ritacco V, Sasiain MDC.

Infect Genet Evol. 2019 May 8;73:248-254. doi: 10.1016/j.meegid.2019.05.005. [Epub ahead of print]


Bedaquiline and linezolid MIC distributions and epidemiological cut-off values for Mycobacterium tuberculosis in the Latin American region.

Lopez B, Siqueira de Oliveira R, Pinhata JMW, Chimara E, Pacheco Ascencio E, Puyén Guerra ZM, Wainmayer I, Simboli N, Del Granado M, Palomino JC, Ritacco V, Martin A.

J Antimicrob Chemother. 2019 Feb 1;74(2):373-379. doi: 10.1093/jac/dky414.


Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation.

Brynildsrud OB, Pepperell CS, Suffys P, Grandjean L, Monteserin J, Debech N, Bohlin J, Alfsnes K, Pettersson JO, Kirkeleite I, Fandinho F, da Silva MA, Perdigao J, Portugal I, Viveiros M, Clark T, Caws M, Dunstan S, Thai PVK, Lopez B, Ritacco V, Kitchen A, Brown TS, van Soolingen D, O'Neill MB, Holt KE, Feil EJ, Mathema B, Balloux F, Eldholm V.

Sci Adv. 2018 Oct 17;4(10):eaat5869. doi: 10.1126/sciadv.aat5869. eCollection 2018 Oct.


[One hundred years after the "Spanish" flu].

Lüthy IA, Ritacco V, Kantor IN.

Medicina (B Aires). 2018;78(2):113-118. Spanish.


Genotypic diversity of Mycobacterium tuberculosis in Buenos Aires, Argentina.

Monteserin J, Paul R, Gravina E, Reniero A, Hernandez T, Mazzeo E, Togneri A, Simboli N, López B, Couvin D, Rastogi N, Ritacco V.

Infect Genet Evol. 2018 Aug;62:1-7. doi: 10.1016/j.meegid.2018.04.006. Epub 2018 Apr 6.


Performance of a highly successful outbreak strain of Mycobacterium tuberculosis in a multifaceted approach to bacterial fitness assessment.

Yokobori N, López B, Monteserin J, Paul R, Von Groll A, Martin A, Marquina-Castillo B, Palomino JC, Hernández-Pando R, Sasiain MDC, Ritacco V.

Int J Med Microbiol. 2018 Apr;308(3):349-357. doi: 10.1016/j.ijmm.2018.01.006. Epub 2018 Jan 31.


Mycobacterium tuberculosis Multidrug-Resistant Strain M Induces Low IL-8 and Inhibits TNF-α Secretion by Bronchial Epithelial Cells Altering Neutrophil Effector Functions.

Kviatcovsky D, Rivadeneyra L, Balboa L, Yokobori N, López B, Ritacco V, Schattner M, Sasiain MDC, de la Barrera S.

Mediators Inflamm. 2017;2017:2810606. doi: 10.1155/2017/2810606. Epub 2017 Aug 9.


Relation of Mycobacterium tuberculosis mutations at katG315 and inhA-15 with drug resistance profile, genetic background, and clustering in Argentina.

Monteserin J, Paul R, Latini C, Simboli N, Yokobori N, Delfederico L, López B, Ritacco V.

Diagn Microbiol Infect Dis. 2017 Nov;89(3):197-201. doi: 10.1016/j.diagmicrobio.2017.07.010. Epub 2017 Jul 28.


Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain.

Bigi MM, Lopez B, Blanco FC, Sasiain MD, De la Barrera S, Marti MA, Sosa EJ, Fernández Do Porto DA, Ritacco V, Bigi F, Soria MA.

Tuberculosis (Edinb). 2017 Mar;103:28-36. doi: 10.1016/ Epub 2017 Jan 4.


C5aR contributes to the weak Th1 profile induced by an outbreak strain of Mycobacterium tuberculosis.

Sabio Y García CA, Yokobori N, Basile JI, Balboa L, González A, López B, Ritacco V, Barrera S, Sasiain MD.

Tuberculosis (Edinb). 2017 Mar;103:16-23. doi: 10.1016/ Epub 2016 Dec 21.


Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis.

Basile JI, Kviatcovsky D, Romero MM, Balboa L, Monteserin J, Ritacco V, Lopez B, Sabio y García C, García A, Vescovo M, Montaner PG, Palmero D, Del Carmen Sasiain M, de la Barrera S.

Clin Exp Immunol. 2017 Jan;187(1):160-173. doi: 10.1111/cei.12873. Epub 2016 Nov 2.


Combined approach to the identification of clinically infrequent non-tuberculous mycobacteria in Argentina.

Monteserin J, Paul R, Lopez B, Cnockaert M, Tortoli E, Menéndez C, García MJ, Palomino JC, Vandamme P, Ritacco V, Martin A.

Int J Tuberc Lung Dis. 2016 Sep;20(9):1257-62. doi: 10.5588/ijtld.16.0122.


Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis.

Eldholm V, Rieux A, Monteserin J, Lopez JM, Palmero D, Lopez B, Ritacco V, Didelot X, Balloux F.

Elife. 2016 Aug 9;5. pii: e16644. doi: 10.7554/eLife.16644.


Reactive oxygen species production by human dendritic cells involves TLR2 and dectin-1 and is essential for efficient immune response against Mycobacteria.

Romero MM, Basile JI, Corra Feo L, López B, Ritacco V, Alemán M.

Cell Microbiol. 2016 Jun;18(6):875-86. doi: 10.1111/cmi.12562. Epub 2016 Jan 26.


[Tuberculosis 110 years after the Nobel Prize awarded to Koch].

Ritacco V, Kantor IN.

Medicina (B Aires). 2015;75(6):396-403. Spanish.


Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain.

Eldholm V, Monteserin J, Rieux A, Lopez B, Sobkowiak B, Ritacco V, Balloux F.

Nat Commun. 2015 May 11;6:7119. doi: 10.1038/ncomms8119.


Differential expression of immunogenic proteins on virulent Mycobacterium tuberculosis clinical isolates.

Schierloh P, Klepp L, Vazquez C, Rocha RV, Blanco FC, Balboa L, López B, Ritacco V, Bigi F, Sasiain Mdel C.

Biomed Res Int. 2014;2014:741309. doi: 10.1155/2014/741309. Epub 2014 Jul 7.


Outbreaks of Mycobacterium tuberculosis MDR strains differentially induce neutrophil respiratory burst involving lipid rafts, p38 MAPK and Syk.

Romero MM, Basile JI, López B, Ritacco V, Barrera L, Sasiain Mdel C, Alemán M.

BMC Infect Dis. 2014 May 16;14:262. doi: 10.1186/1471-2334-14-262.


Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cells.

Geffner L, Basile JI, Yokobori N, Kviatcovsky D, Sabio y García C, Ritacco V, López B, Sasiain Mdel C, de la Barrera S.

PLoS One. 2014 May 16;9(5):e97837. doi: 10.1371/journal.pone.0097837. eCollection 2014.


Genotypes of Mycobacterium tuberculosis in patients at risk of drug resistance in Bolivia.

Monteserin J, Camacho M, Barrera L, Palomino JC, Ritacco V, Martin A.

Infect Genet Evol. 2013 Jul;17:195-201. doi: 10.1016/j.meegid.2013.04.010. Epub 2013 Apr 17.


Two genetically-related multidrug-resistant Mycobacterium tuberculosis strains induce divergent outcomes of infection in two human macrophage models.

Yokobori N, López B, Geffner L, Sabio y García C, Schierloh P, Barrera L, de la Barrera S, Sakai S, Kawamura I, Mitsuyama M, Ritacco V, Sasiain Mdel C.

Infect Genet Evol. 2013 Jun;16:151-6. doi: 10.1016/j.meegid.2013.01.007. Epub 2013 Jan 24.


HIV infection and geographically bound transmission of drug-resistant tuberculosis, Argentina.

Ritacco V, López B, Ambroggi M, Palmero D, Salvadores B, Gravina E, Mazzeo E; National TB Laboratory Network, Imaz S, Barrera L.

Emerg Infect Dis. 2012 Nov;18(11):1802-10. doi: 10.3201/eid1811.120126.


Differential induction of macrophage cell death by antigens of a clustered and a non-clustered multidrug-resistant Mycobacterium tuberculosis strain from Haarlem family.

Yokobori N, Sabio y García CA, Geffner L, Schierloh P, López B, Ritacco V, Barrera L, de la Barrera S, del Carmen Saisiain M.

FEMS Immunol Med Microbiol. 2012 Dec;66(3):363-71. doi: 10.1111/j.1574-695X.2012.01024.x. Epub 2012 Sep 10.


Clinical isolates of Mycobacterium tuberculosis differ in their ability to induce respiratory burst and apoptosis in neutrophils as a possible mechanism of immune escape.

Romero MM, Balboa L, Basile JI, López B, Ritacco V, de la Barrera SS, Sasiain MC, Barrera L, Alemán M.

Clin Dev Immunol. 2012;2012:152546. doi: 10.1155/2012/152546. Epub 2012 Jun 21.


IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes.

Reyes A, Sandoval A, Cubillos-Ruiz A, Varley KE, Hernández-Neuta I, Samper S, Martín C, García MJ, Ritacco V, López L, Robledo J, Zambrano MM, Mitra RD, Del Portillo P.

BMC Genomics. 2012 Jun 15;13:249. doi: 10.1186/1471-2164-13-249.


Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine.

Abbate E, Vescovo M, Natiello M, Cufré M, García A, Gonzalez Montaner P, Ambroggi M, Ritacco V, van Soolingen D.

J Antimicrob Chemother. 2012 Feb;67(2):473-7. doi: 10.1093/jac/dkr500. Epub 2011 Dec 1.


Modelling the feasibility of bovine tuberculosis eradication in Argentina.

Perezill AM, Ward MP, Ritacco V.

Rev Sci Tech. 2011 Aug;30(2):635-43.


Outbreaks of mycobacterium tuberculosis MDR strains induce high IL-17 T-cell response in patients with MDR tuberculosis that is closely associated with high antigen load.

Basile JI, Geffner LJ, Romero MM, Balboa L, Sabio Y García C, Ritacco V, García A, Cuffré M, Abbate E, López B, Barrera L, Ambroggi M, Alemán M, Sasiain MC, de la Barrera SS.

J Infect Dis. 2011 Oct 1;204(7):1054-64. doi: 10.1093/infdis/jir460.


Conspicuous multidrug-resistant Mycobacterium tuberculosis cluster strains do not trespass country borders in Latin America and Spain.

Ritacco V, Iglesias MJ, Ferrazoli L, Monteserin J, Dalla Costa ER, Cebollada A, Morcillo N, Robledo J, de Waard JH, Araya P, Aristimuño L, Díaz R, Gavin P, Imperiale B, Simonsen V, Zapata EM, Jiménez MS, Rossetti ML, Martin C, Barrera L, Samper S.

Infect Genet Evol. 2012 Jun;12(4):711-7. doi: 10.1016/j.meegid.2011.06.006. Epub 2011 Jun 21.


The use of microbead-based spoligotyping for Mycobacterium tuberculosis complex to evaluate the quality of the conventional method: providing guidelines for Quality Assurance when working on membranes.

Abadia E, Zhang J, Ritacco V, Kremer K, Ruimy R, Rigouts L, Gomes HM, Elias AR, Fauville-Dufaux M, Stoffels K, Rasolofo-Razanamparany V, Garcia de Viedma D, Herranz M, Al-Hajoj S, Rastogi N, Garzelli C, Tortoli E, Suffys PN, van Soolingen D, Refrégier G, Sola C.

BMC Infect Dis. 2011 Apr 28;11:110. doi: 10.1186/1471-2334-11-110.


AIDS pacient's long-term battle with multiply recurrent tuberculosis: reinfection or reactivation?

Reniero A, Beltrán M, de Kantor IN, Ritacco V.

Rev Argent Microbiol. 2010 Oct-Dec;42(4):271-3. doi: 10.1590/S0325-75412010000400006.


Rifampin-isoniazid oligonucleotide typing: an alternative format for rapid detection of multidrug-resistant Mycobacterium tuberculosis.

Hernández-Neuta I, Varela A, Martin A, von Groll A, Jureen P, López B, Imperiale B, Sķenders G, Ritacco V, Hoffner S, Morcillo N, Palomino JC, Del Portillo P.

J Clin Microbiol. 2010 Dec;48(12):4386-91. doi: 10.1128/JCM.00448-10. Epub 2010 Sep 29.


Genomic signatures of the haarlem lineage of Mycobacterium tuberculosis: implications of strain genetic variation in drug and vaccine development.

Cubillos-Ruiz A, Sandoval A, Ritacco V, López B, Robledo J, Correa N, Hernandez-Neuta I, Zambrano MM, Del Portillo P.

J Clin Microbiol. 2010 Oct;48(10):3614-23. doi: 10.1128/JCM.00157-10. Epub 2010 Jul 14.


Resolving lineage assignation on Mycobacterium tuberculosis clinical isolates classified by spoligotyping with a new high-throughput 3R SNPs based method.

Abadia E, Zhang J, dos Vultos T, Ritacco V, Kremer K, Aktas E, Matsumoto T, Refregier G, van Soolingen D, Gicquel B, Sola C.

Infect Genet Evol. 2010 Oct;10(7):1066-74. doi: 10.1016/j.meegid.2010.07.006. Epub 2010 Jul 17.


Differences in the robustness of clusters involving the Mycobacterium tuberculosis strains most frequently isolated from immigrant cases in Madrid.

Rodríguez NA, Lirola MM, Chaves F, Iñigo J, Herranz M, Ritacco V; EpiMOLTB Madrid; INDAL-TB group, Bouza E, García de Viedma D.

Clin Microbiol Infect. 2010 Oct;16(10):1544-54. doi: 10.1111/j.1469-0691.2010.03161.x. Epub 2010 Jan 27.


Patients with multidrug-resistant tuberculosis display impaired Th1 responses and enhanced regulatory T-cell levels in response to an outbreak of multidrug-resistant Mycobacterium tuberculosis M and Ra strains.

Geffner L, Yokobori N, Basile J, Schierloh P, Balboa L, Romero MM, Ritacco V, Vescovo M, González Montaner P, Lopez B, Barrera L, Alemán M, Abatte E, Sasiain MC, de la Barrera S.

Infect Immun. 2009 Nov;77(11):5025-34. doi: 10.1128/IAI.00224-09. Epub 2009 Aug 31.


[Is the tuberculin skin test still suitable to diagnose tuberculosis infection ?].

de Kantor IN, Ritacco V.

Medicina (B Aires). 2009;69(3):359-69. Spanish.


Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America.

Dalla Costa ER, Ribeiro MO, Silva MS, Arnold LS, Rostirolla DC, Cafrune PI, Espinoza RC, Palaci M, Telles MA, Ritacco V, Suffys PN, Lopes ML, Campelo CL, Miranda SS, Kremer K, da Silva PE, Fonseca Lde S, Ho JL, Kritski AL, Rossetti ML.

BMC Microbiol. 2009 Feb 19;9:39. doi: 10.1186/1471-2180-9-39.


Mesotherapy-associated outbreak caused by Mycobacterium immunogenum.

Del-Castillo M, Palmero D, Lopez B, Paul R, Ritacco V, Bonvehi P, Clara L, Ambroggi M, Barrera L, Vay C.

Emerg Infect Dis. 2009 Feb;15(2):357-9. No abstract available.


Mycobacterium tuberculosis strains of the Beijing genotype are rarely observed in tuberculosis patients in South America.

Ritacco V, López B, Cafrune PI, Ferrazoli L, Suffys PN, Candia N, Vásquez L, Realpe T, Fernández J, Lima KV, Zurita J, Robledo J, Rossetti ML, Kritski AL, Telles MA, Palomino JC, Heersma H, van Soolingen D, Kremer K, Barrera L.

Mem Inst Oswaldo Cruz. 2008 Aug;103(5):489-92.


Indigenous dengue fever, Buenos Aires, Argentina.

Natiello M, Ritacco V, Morales MA, Deodato B, Picollo M, Dinerstein E, Enria D.

Emerg Infect Dis. 2008 Sep;14(9):1498-9. doi: 10.3201/eid1409.080143. No abstract available.


Mutations in DNA repair genes are associated with the Haarlem lineage of Mycobacterium tuberculosis independently of their antibiotic resistance.

Olano J, López B, Reyes A, Lemos MP, Correa N, Del Portillo P, Barrera L, Robledo J, Ritacco V, Zambrano MM.

Tuberculosis (Edinb). 2007 Nov;87(6):502-8. Epub 2007 Oct 4.


First insight into Mycobacterium tuberculosis genetic diversity in Paraguay.

Candia N, Lopez B, Zozio T, Carrivale M, Diaz C, Russomando G, de Romero NJ, Jara JC, Barrera L, Rastogi N, Ritacco V.

BMC Microbiol. 2007 Aug 8;7:75.


[False diagnosis of tuberculosis by culture].

Alonso V, Paul R, Barrera L, Ritacco V.

Medicina (B Aires). 2007;67(3):287-94. Spanish.


Simultaneous detection of Mycobacterium bovis and Mycobacterium tuberculosis in human cerebrospinal fluid.

Ritacco V, de Kantor IN.

J Clin Microbiol. 2007 Feb;45(2):684. No abstract available.


[Multidrug-resistant tuberculosis in AIDS patients at the beginning of the millennium].

Palmero D, Ritacco V, Ambroggi M, Poggi S, Güemes Gurtubay J, Alberti F, Waisman J.

Medicina (B Aires). 2006;66(5):399-404. Spanish. Erratum in: Medicina (B Aires). 2006;66(6):598.


An update on bovine tuberculosis programmes in Latin American and Caribbean countries.

de Kantor IN, Ritacco V.

Vet Microbiol. 2006 Feb 25;112(2-4):111-8. Epub 2005 Nov 28.


Multidrug-resistant tuberculosis outbreak among transvestite sex workers, Buenos Aires, Argentina.

Palmero D, Ritacco V, Ruano S, Ambroggi M, Cusmano L, Romano M, Bucci Z, Waisman J.

Int J Tuberc Lung Dis. 2005 Oct;9(10):1168-70.


Tuberculosis transmission in police stations in a suburb of Buenos Aires, Argentina.

Ortiz MC, Viera GA, Gravina E, Gurtman A, Barrera LE, Ritacco V.

Int J Tuberc Lung Dis. 2005 Sep;9(9):1058-9. No abstract available.


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