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Items: 15


An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.

Airhart SE, Shireman LM, Risler LJ, Anderson GD, Nagana Gowda GA, Raftery D, Tian R, Shen DD, O'Brien KD.

PLoS One. 2017 Dec 6;12(12):e0186459. doi: 10.1371/journal.pone.0186459. eCollection 2017.


Hyperthermia-enhanced targeted drug delivery using magnetic resonance-guided focussed ultrasound: a pre-clinical study in a genetic model of pancreatic cancer.

Farr N, Wang YN, D'Andrea S, Starr F, Partanen A, Gravelle KM, McCune JS, Risler LJ, Whang SG, Chang A, Hingorani SR, Lee D, Hwang JH.

Int J Hyperthermia. 2018 May;34(3):284-291. doi: 10.1080/02656736.2017.1336675. Epub 2017 Jul 17.


P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine.

Liao MZ, Gao C, Shireman LM, Phillips B, Risler LJ, Neradugomma NK, Choudhari P, Prasad B, Shen DD, Mao Q.

Pharmacol Res. 2017 May;119:61-71. doi: 10.1016/j.phrs.2017.01.018. Epub 2017 Jan 19.


Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer.

Li T, Wang YN, Khokhlova TD, D'Andrea S, Starr F, Chen H, McCune JS, Risler LJ, Mashadi-Hossein A, Hingorani SR, Chang A, Hwang JH.

Cancer Res. 2015 Sep 15;75(18):3738-46. doi: 10.1158/0008-5472.CAN-15-0296. Epub 2015 Jul 27. Erratum in: Cancer Res. 2017 May 15;77(10 ):2771.


Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects.

Claessens AJ, Yeung CK, Risler LJ, Phillips BR, Himmelfarb J, Shen DD.

Ann Clin Biochem. 2016 Mar;53(Pt 2):265-73. doi: 10.1177/0004563215593097. Epub 2015 Jun 8.


Identification of CYP3A7 for glyburide metabolism in human fetal livers.

Shuster DL, Risler LJ, Prasad B, Calamia JC, Voellinger JL, Kelly EJ, Unadkat JD, Hebert MF, Shen DD, Thummel KE, Mao Q.

Biochem Pharmacol. 2014 Dec 15;92(4):690-700. doi: 10.1016/j.bcp.2014.09.025. Epub 2014 Oct 22.


Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.

Bemer MJ, Risler LJ, Phillips BR, Wang J, Storer BE, Sandmaier BM, Duan H, Raccor BS, Boeckh MJ, McCune JS.

Biol Blood Marrow Transplant. 2014 Oct;20(10):1544-52. doi: 10.1016/j.bbmt.2014.05.032. Epub 2014 Jun 9.


Maternal-fetal disposition of glyburide in pregnant mice is dependent on gestational age.

Shuster DL, Risler LJ, Liang CK, Rice KM, Shen DD, Hebert MF, Thummel KE, Mao Q.

J Pharmacol Exp Ther. 2014 Aug;350(2):425-34. doi: 10.1124/jpet.114.213470. Epub 2014 Jun 4.


Pharmacokinetic and pharmacodynamic analysis of inosine monophosphate dehydrogenase activity in hematopoietic cell transplantation recipients treated with mycophenolate mofetil.

Li H, Mager DE, Sandmaier BM, Storer BE, Boeckh MJ, Bemer MJ, Phillips BR, Risler LJ, McCune JS.

Biol Blood Marrow Transplant. 2014 Aug;20(8):1121-9. doi: 10.1016/j.bbmt.2014.03.032. Epub 2014 Apr 13.


CYP2D6 mediates 4-hydroxylation of clonidine in vitro: implication for pregnancy-induced changes in clonidine clearance.

Claessens AJ, Risler LJ, Eyal S, Shen DD, Easterling TR, Hebert MF.

Drug Metab Dispos. 2010 Sep;38(9):1393-6. doi: 10.1124/dmd.110.033878. Epub 2010 Jun 22.


Clonidine pharmacokinetics in pregnancy.

Buchanan ML, Easterling TR, Carr DB, Shen DD, Risler LJ, Nelson WL, Mattison DR, Hebert MF.

Drug Metab Dispos. 2009 Apr;37(4):702-5. doi: 10.1124/dmd.108.024984. Epub 2008 Dec 30.


Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation.

McCune JS, Risler LJ, Phillips BR, Thummel KE, Blough D, Shen DD.

Drug Metab Dispos. 2005 Jul;33(7):1074-81. Epub 2005 Apr 8.


Target dose adjustment of busulfan in pediatric patients undergoing bone marrow transplantation.

Bolinger AM, Zangwill AB, Slattery JT, Risler LJ, Sultan DH, Glidden DV, Norstad D, Cowan MJ.

Bone Marrow Transplant. 2001 Dec;28(11):1013-8.


An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease.

Bolinger AM, Zangwill AB, Slattery JT, Glidden D, DeSantes K, Heyn L, Risler LJ, Bostrom B, Cowan MJ.

Bone Marrow Transplant. 2000 May;25(9):925-30.


Therapeutic monitoring of busulfan in hematopoietic stem cell transplantation.

Slattery JT, Risler LJ.

Ther Drug Monit. 1998 Oct;20(5):543-9. Review.


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