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Items: 1 to 50 of 98

1.

A H2AX⁻CARP-1 Interaction Regulates Apoptosis Signaling Following DNA Damage.

Sekhar SC, Venkatesh J, Cheriyan VT, Muthu M, Levi E, Assad H, Meister P, Undyala VV, Gauld JW, Rishi AK.

Cancers (Basel). 2019 Feb 14;11(2). pii: E221. doi: 10.3390/cancers11020221.

2.

AT1 receptors in the subfornical organ modulate arterial pressure and the baroreflex in two-kidney, one-clip hypertensive rats.

Rossi NF, Zenner Z, Rishi AK, Levi E, Maliszewska-Scislo M.

Am J Physiol Regul Integr Comp Physiol. 2019 Feb 1;316(2):R172-R185. doi: 10.1152/ajpregu.00289.2018. Epub 2019 Jan 9.

PMID:
30624974
3.

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Alsaab HO, Sau S, Alzhrani RM, Cheriyan VT, Polin LA, Vaishampayan U, Rishi AK, Iyer AK.

Biomaterials. 2018 Nov;183:280-294. doi: 10.1016/j.biomaterials.2018.08.053. Epub 2018 Aug 30.

PMID:
30179778
4.

A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers.

Cheriyan VT, Alsaab H, Sekhar S, Venkatesh J, Mondal A, Vhora I, Sau S, Muthu M, Polin LA, Levi E, Bepler G, Iyer AK, Singh M, Rishi AK.

Oncotarget. 2018 Jul 3;9(51):29680-29697. doi: 10.18632/oncotarget.25671. eCollection 2018 Jul 3.

5.

A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma.

Cheriyan VT, Alsaab HO, Sekhar S, Stieber C, Kesharwani P, Sau S, Muthu M, Polin LA, Levi E, Iyer AK, Rishi AK.

Oncotarget. 2017 Sep 5;8(62):104928-104945. doi: 10.18632/oncotarget.20650. eCollection 2017 Dec 1.

6.

SM22α suppresses cytokine-induced inflammation and the transcription of NF-κB inducing kinase (Nik) by modulating SRF transcriptional activity in vascular smooth muscle cells.

Dai X, Thiagarajan D, Fang J, Shen J, Annam NP, Yang Z, Jiang H, Ju D, Xie Y, Zhang K, Tseng YY, Yang Z, Rishi AK, Li HJ, Yang M, Li L.

PLoS One. 2017 Dec 28;12(12):e0190191. doi: 10.1371/journal.pone.0190191. eCollection 2017.

7.

Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells.

Yin S, Cheryan VT, Xu L, Rishi AK, Reddy KB.

PLoS One. 2017 Aug 17;12(8):e0183578. doi: 10.1371/journal.pone.0183578. eCollection 2017.

8.

Di-Block PLCL and Tri-Block PLCLG Matrix Polymeric Nanoparticles Enhanced the Anticancer Activity of Loaded 5-Fluorouracil.

Ashour AE, Badran MM, Kumar A, Rishi AK, Yassin AE.

IEEE Trans Nanobioscience. 2016 Oct;15(7):739-747. doi: 10.1109/TNB.2016.2612340.

PMID:
28029617
9.

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers.

Cheriyan VT, Muthu M, Patel K, Sekhar S, Rajeswaran W, Larsen SD, Polin L, Levi E, Singh M, Rishi AK.

Oncotarget. 2016 Nov 8;7(45):73370-73388. doi: 10.18632/oncotarget.12333.

10.

Solubility enhancement and targeted delivery of a potent anticancer flavonoid analogue to cancer cells using ligand decorated dendrimer nano-architectures.

Luong D, Kesharwani P, Killinger BA, Moszczynska A, Sarkar FH, Padhye S, Rishi AK, Iyer AK.

J Colloid Interface Sci. 2016 Dec 15;484:33-43. doi: 10.1016/j.jcis.2016.08.061. Epub 2016 Aug 24.

PMID:
27585998
11.

Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression.

Ashour AE, Ahmed AF, Kumar A, Zoheir KM, Aboul-Soud MA, Ahmad SF, Attia SM, Abd-Allah AR, Cheryan VT, Rishi AK.

Mol Cell Biochem. 2016 May;416(1-2):141-55. doi: 10.1007/s11010-016-2703-4. Epub 2016 Apr 15.

PMID:
27084536
12.

Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine.

Andey T, Patel A, Marepally S, Chougule M, Spencer SD, Rishi AK, Singh M.

PLoS One. 2016 Jan 12;11(1):e0146804. doi: 10.1371/journal.pone.0146804. eCollection 2016.

13.

Identification and Testing of Novel CARP-1 Functional Mimetic Compounds as Inhibitors of Non-Small Cell Lung and Triple Negative Breast Cancers.

Muthu M, Somagoni J, Cheriyan VT, Munie S, Levi E, Ashour AE, Yassin AE, Alafeefy AM, Sochacki P, Polin LA, Reddy KB, Larsen SD, Singh M, Rishi AK.

J Biomed Nanotechnol. 2015 Sep;11(9):1608-27.

14.

PTHrP attenuates osteoblast cell death and apoptosis induced by a novel class of anti-cancer agents.

Chukkapalli S, Levi E, Rishi AK, Datta NS.

Endocrine. 2016 Mar;51(3):534-44. doi: 10.1007/s12020-015-0699-2. Epub 2015 Aug 11.

PMID:
26260694
15.

CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis.

Muthu M, Cheriyan VT, Rishi AK.

Oncotarget. 2015 Mar 30;6(9):6499-510. Review.

16.

Anti-estrogen‑resistant breast cancer cells are sensitive to cisplatin plus TRAIL treatment.

Yin S, Rishi AK, Reddy KB.

Oncol Rep. 2015 Mar;33(3):1475-80. doi: 10.3892/or.2015.3721. Epub 2015 Jan 14.

PMID:
25592673
17.

Development of certain novel N-(2-(2-(2-oxoindolin-3-ylidene)hydrazinecarbonyl)phenyl)-benzamides and 3-(2-oxoindolin-3-ylideneamino)-2-substituted quinazolin-4(3H)-ones as CFM-1 analogs: design, synthesis, QSAR analysis and anticancer activity.

Alafeefy AM, Ashour AE, Prasad O, Sinha L, Pathak S, Alasmari FA, Rishi AK, Abdel-Aziz HA.

Eur J Med Chem. 2015 Mar 6;92:191-201. doi: 10.1016/j.ejmech.2014.12.048. Epub 2014 Dec 27.

PMID:
25555142
18.

Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.

Zhang X, Tang N, Rishi AK, Pass HI, Wali A.

Methods Mol Biol. 2015;1238:235-47. doi: 10.1007/978-1-4939-1804-1_12. Review.

PMID:
25421663
19.

Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics.

Muthu M, Cheriyan VT, Munie S, Levi E, Frank J, Ashour AE, Singh M, Rishi AK.

PLoS One. 2014 Jul 17;9(7):e102567. doi: 10.1371/journal.pone.0102567. eCollection 2014.

20.

Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.

Cheriyan VT, Wang Y, Muthu M, Jamal S, Chen D, Yang H, Polin LA, Tarca AL, Pass HI, Dou QP, Sharma S, Wali A, Rishi AK.

PLoS One. 2014 Apr 1;9(4):e93711. doi: 10.1371/journal.pone.0093711. eCollection 2014.

21.

CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells.

Jamal S, Cheriyan VT, Muthu M, Munie S, Levi E, Ashour AE, Pass HI, Wali A, Singh M, Rishi AK.

PLoS One. 2014 Mar 5;9(3):e89146. doi: 10.1371/journal.pone.0089146. eCollection 2014.

22.

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis.

Ashour AE, Abd-Allah AR, Korashy HM, Attia SM, Alzahrani AZ, Saquib Q, Bakheet SA, Abdel-Hamied HE, Jamal S, Rishi AK.

Mol Cell Biochem. 2014 Apr;389(1-2):85-98. doi: 10.1007/s11010-013-1930-1. Epub 2014 Jan 8.

PMID:
24399465
23.

CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth.

Ashour AE, Jamal S, Cheryan VT, Muthu M, Zoheir KM, Alafeefy AM, Abd-Allah AR, Levi E, Tarca AL, Polin LA, Rishi AK.

PLoS One. 2013 Jun 24;8(6):e66733. doi: 10.1371/journal.pone.0066733. Print 2013.

24.

Cell cycle and apoptosis regulatory protein (CARP)-1 is expressed in osteoblasts and regulated by PTH.

Sharma S, Mahalingam CD, Das V, Jamal S, Levi E, Rishi AK, Datta NS.

Biochem Biophys Res Commun. 2013 Jul 12;436(4):607-12. doi: 10.1016/j.bbrc.2013.05.136. Epub 2013 Jun 11.

25.

Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.

Farhana L, Dawson MI, Murshed F, Das JK, Rishi AK, Fontana JA.

PLoS One. 2013 May 10;8(5):e61015. doi: 10.1371/journal.pone.0061015. Print 2013.

26.

Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo.

Yang H, Wang Y, Cheryan VT, Wu W, Cui CQ, Polin LA, Pass HI, Dou QP, Rishi AK, Wali A.

PLoS One. 2012;7(8):e41214. doi: 10.1371/journal.pone.0041214. Epub 2012 Aug 17.

27.

Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis.

Puliyappadamba VT, Wu W, Bevis D, Zhang L, Polin L, Kilkuskie R, Finley RL Jr, Larsen SD, Levi E, Miller FR, Wali A, Rishi AK.

J Biol Chem. 2011 Nov 4;286(44):38000-17. doi: 10.1074/jbc.M111.222398. Epub 2011 Sep 8.

28.

Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis.

Wang Y, Rishi AK, Wu W, Polin L, Sharma S, Levi E, Albelda S, Pass HI, Wali A.

Mol Cell Biochem. 2011 Nov;357(1-2):83-94. doi: 10.1007/s11010-011-0878-2. Epub 2011 May 19.

29.

Akt, FoxO and regulation of apoptosis.

Zhang X, Tang N, Hadden TJ, Rishi AK.

Biochim Biophys Acta. 2011 Nov;1813(11):1978-86. doi: 10.1016/j.bbamcr.2011.03.010. Epub 2011 Mar 31. Review.

30.

Cell cycle and apoptosis regulatory protein (CARP)-1 is a novel, adriamycin-inducible, diffuse large B-cell lymphoma (DLBL) growth suppressor.

Levi E, Zhang L, Aboukameel A, Rishi S, Mohammad RM, Polin L, Hatfield JS, Rishi AK.

Cancer Chemother Pharmacol. 2011 Jun;67(6):1401-13. doi: 10.1007/s00280-010-1442-6. Epub 2010 Aug 31.

31.

Novel cis-trans interactions are involved in post-transcriptional regulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1 mRNA.

Zhang L, Wali A, Fontana JA, Dawson MI, Rishi AK.

J Mol Signal. 2010 Aug 12;5:12. doi: 10.1186/1750-2187-5-12.

32.

A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1.

Jiang Y, Puliyappadamba VT, Zhang L, Wu W, Wali A, Yaffe MB, Fontana JA, Rishi AK.

J Mol Signal. 2010 Jul 1;5:7. doi: 10.1186/1750-2187-5-7.

33.

ErbB-inhibitory protein: a modified ectodomain of epidermal growth factor receptor synergizes with dasatinib to inhibit growth of breast cancer cells.

Nautiyal J, Yu Y, Aboukameel A, Kanwar SS, Das JK, Du J, Patel BB, Sarkar FH, Rishi AK, Mohammad RM, Majumdar AP.

Mol Cancer Ther. 2010 Jun;9(6):1503-14. doi: 10.1158/1535-7163.MCT-10-0019. Epub 2010 Jun 1. Erratum in: Mol Cancer Ther. 2010 Sep;9(9):2637.

34.

Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines.

Wang Y, Rishi AK, Puliyappadamba VT, Sharma S, Yang H, Tarca A, Dou QP, Lonardo F, Ruckdeschel JC, Pass HI, Wali A.

Cancer Chemother Pharmacol. 2010 Aug;66(3):455-66. doi: 10.1007/s00280-009-1181-8. Epub 2009 Dec 4.

35.

Schlafen 3, a novel gene, regulates colonic mucosal growth during aging.

Patel BB, Yu Y, Du J, Rishi AK, Sarkar FH, Tarca AL, Wali A, Majumdar AP.

Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G955-62. doi: 10.1152/ajpgi.90726.2008. Epub 2009 Feb 19.

36.

Cigarette smoke, inflammation, and lung injury: a mechanistic perspective.

Bhalla DK, Hirata F, Rishi AK, Gairola CG.

J Toxicol Environ Health B Crit Rev. 2009 Jan;12(1):45-64. doi: 10.1080/10937400802545094. Review.

PMID:
19117209
37.

Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules.

Kolobova E, Efimov A, Kaverina I, Rishi AK, Schrader JW, Ham AJ, Larocca MC, Goldenring JR.

Exp Cell Res. 2009 Feb 1;315(3):542-55. doi: 10.1016/j.yexcr.2008.11.011. Epub 2008 Dec 3.

38.

TGF-beta1 modulates focal adhesion kinase expression in rat intestinal epithelial IEC-6 cells via stimulatory and inhibitory Smad binding elements.

Walsh MF, Ampasala DR, Rishi AK, Basson MD.

Biochim Biophys Acta. 2009 Feb;1789(2):88-98. doi: 10.1016/j.bbagrm.2008.11.002. Epub 2008 Nov 14.

39.

Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.

Walsh MF, Ampasala DR, Hatfield J, Vander Heide R, Suer S, Rishi AK, Basson MD.

Am J Pathol. 2008 Aug;173(2):385-99. doi: 10.2353/ajpath.2008.070729. Epub 2008 Jun 26.

40.
41.

Cell cycle and apoptosis regulatory protein-1: a novel regulator of apoptosis in the colonic mucosa during aging.

Majumdar AP, Du J, Yu Y, Xu H, Levi E, Patel BB, Rishi AK.

Am J Physiol Gastrointest Liver Physiol. 2007 Dec;293(6):G1215-22. Epub 2007 Oct 11.

42.

Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.

Patel BB, Sengupta R, Qazi S, Vachhani H, Yu Y, Rishi AK, Majumdar AP.

Int J Cancer. 2008 Jan 15;122(2):267-73.

43.

Regression of early and intermediate stages of colon cancer by targeting multiple members of the EGFR family with EGFR-related protein.

Schmelz EM, Xu H, Sengupta R, Du J, Banerjee S, Sarkar FH, Rishi AK, Majumdar AP.

Cancer Res. 2007 Jun 1;67(11):5389-96.

44.

Transactivator of transcription-tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo.

Zhang L, Levi E, Majumder P, Yu Y, Aboukameel A, Du J, Xu H, Mohammad R, Hatfield JS, Wali A, Adsay V, Majumdar AP, Rishi AK.

Mol Cancer Ther. 2007 May;6(5):1661-72.

45.

Emerging therapies in gastrointestinal cancers.

Nautiyal J, Rishi AK, Majumdar AP.

World J Gastroenterol. 2006 Dec 14;12(46):7440-50. Review.

46.

Pressure stimulates breast cancer cell adhesion independently of cell cycle and apoptosis regulatory protein (CARP)-1 regulation of focal adhesion kinase.

Downey C, Alwan K, Thamilselvan V, Zhang L, Jiang Y, Rishi AK, Basson MD.

Am J Surg. 2006 Nov;192(5):631-5.

PMID:
17071197
47.

Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.

Reddy S, Rishi AK, Xu H, Levi E, Sarkar FH, Majumdar AP.

Nutr Cancer. 2006;55(2):185-94.

PMID:
17044774
48.

EGF receptor-related protein (ERRP) inhibits invasion of colon cancer cells and tubule formation by endothelial cells in vitro.

Rishi AK, Parikh R, Wali A, Durko L, Zhang L, Yu Y, Majumdar AP.

Anticancer Res. 2006 Mar-Apr;26(2A):1029-37.

49.

Cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor.

Rishi AK, Zhang L, Yu Y, Jiang Y, Nautiyal J, Wali A, Fontana JA, Levi E, Majumdar AP.

J Biol Chem. 2006 May 12;281(19):13188-98. Epub 2006 Mar 16.

50.

Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells.

Xu H, Yu Y, Marciniak D, Rishi AK, Sarkar FH, Kucuk O, Majumdar AP.

Mol Cancer Ther. 2005 Mar;4(3):435-42.

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