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Items: 37

1.

Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer.

Shi B, Behrens C, Vaghani V, Riquelme EM, Rodriguez-Canales J, Kadara H, Lin H, Lee J, Liu H, Wistuba I, Simon G.

Cancer Med. 2019 Aug 27. doi: 10.1002/cam4.1855. [Epub ahead of print]

2.

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.

Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F.

Cell. 2019 Aug 8;178(4):795-806.e12. doi: 10.1016/j.cell.2019.07.008.

PMID:
31398337
3.

Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.

Chang K, Taggart MW, Reyes-Uribe L, Borras E, Riquelme E, Barnett RM, Leoni G, San Lucas FA, Catanese MT, Mori F, Diodoro MG, You YN, Hawk ET, Roszik J, Scheet P, Kopetz S, Nicosia A, Scarselli E, Lynch PM, McAllister F, Vilar E.

JAMA Oncol. 2018 Aug 1;4(8):1085-1092. doi: 10.1001/jamaoncol.2018.1482.

4.

Immunotherapy for Pancreatic Cancer: More Than Just a Gut Feeling.

Riquelme E, Maitra A, McAllister F.

Cancer Discov. 2018 Apr;8(4):386-388. doi: 10.1158/2159-8290.CD-18-0123.

5.

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells.

Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z, Ling J, Gupta S, Horne W, Pruski M, Wang H, Sun SC, Lozano G, Chiao P, Maitra A, Leach SD, Kolls JK, Vilar E, Wang TC, Bailey JM, McAllister F.

Gastroenterology. 2018 Jul;155(1):210-223.e3. doi: 10.1053/j.gastro.2018.03.041. Epub 2018 Mar 29.

6.

Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson's disease.

Elgueta D, Aymerich MS, Contreras F, Montoya A, Celorrio M, Rojo-Bustamante E, Riquelme E, González H, Vásquez M, Franco R, Pacheco R.

Neuropharmacology. 2017 Feb;113(Pt A):110-123. doi: 10.1016/j.neuropharm.2016.09.028. Epub 2016 Sep 28.

PMID:
27693549
7.

Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.

Jadhavar PS, Ramachandran SA, Riquelme E, Gupta A, Quinn KP, Shivakumar D, Ray S, Zende D, Nayak AK, Miglani SK, Sathe BD, Raja M, Farias O, Alfaro I, Belmar S, Guerrero J, Bernales S, Chakravarty S, Hung DT, Lindquist JN, Rai R.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. doi: 10.1016/j.bmcl.2016.09.058. Epub 2016 Oct 4.

PMID:
27717544
8.

Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.

Rai R, Banerjee M, Wong DH, McCullagh E, Gupta A, Tripathi S, Riquelme E, Jangir R, Yadav S, Raja M, Melkani P, Dixit V, Patil U, Shrivastava R, Middya S, Olivares F, Guerrero J, Surya A, Pham SM, Bernales S, Protter AA, Hung DT, Chakravarty S.

Bioorg Med Chem Lett. 2016 Oct 15;26(20):5103-5109. doi: 10.1016/j.bmcl.2016.08.064. Epub 2016 Aug 21.

PMID:
27614414
9.

Galectin-8 promotes migration and proliferation and prevents apoptosis in U87 glioblastoma cells.

Metz C, Döger R, Riquelme E, Cortés P, Holmes C, Shaughnessy R, Oyanadel C, Grabowski C, González A, Soza A.

Biol Res. 2016 Jul 27;49(1):33. doi: 10.1186/s40659-016-0091-6.

10.

Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations.

Riquelme E, Behrens C, Lin HY, Simon G, Papadimitrakopoulou V, Izzo J, Moran C, Kalhor N, Lee JJ, Minna JD, Wistuba II.

Cancer Res. 2016 Feb 1;76(3):675-85. doi: 10.1158/0008-5472.CAN-15-1141. Epub 2015 Dec 16.

11.

Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma.

Riquelme E, Suraokar MB, Rodriguez J, Mino B, Lin HY, Rice DC, Tsao A, Wistuba II.

J Thorac Oncol. 2014 Jul;9(7):998-1007. doi: 10.1097/JTO.0000000000000202.

12.

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.

Riquelme E, Suraokar M, Behrens C, Lin HY, Girard L, Nilsson MB, Simon G, Wang J, Coombes KR, Lee JJ, Hong WK, Heymach J, Minna JD, Wistuba II.

Clin Cancer Res. 2014 Jul 15;20(14):3849-61. doi: 10.1158/1078-0432.CCR-13-1916. Epub 2014 May 21.

13.

EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma.

Behrens C, Solis LM, Lin H, Yuan P, Tang X, Kadara H, Riquelme E, Galindo H, Moran CA, Kalhor N, Swisher SG, Simon GR, Stewart DJ, Lee JJ, Wistuba II.

Clin Cancer Res. 2013 Dec 1;19(23):6556-65. doi: 10.1158/1078-0432.CCR-12-3946. Epub 2013 Oct 4.

14.
15.

Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis.

Macanas-Pirard P, Leisewitz A, Broekhuizen R, Cautivo K, Barriga FM, Leisewitz F, Gidi V, Riquelme E, Montecinos VP, Swett P, Besa P, Ramirez P, Ocqueteau M, Kalergis AM, Holt M, Rettig M, DiPersio JF, Nervi B.

PLoS One. 2012;7(5):e37203. doi: 10.1371/journal.pone.0037203. Epub 2012 May 22.

16.

A confirmatory factor analysis of the "Autoconcepto Forma 5" questionnaire in young adults from Spain and Chile.

García JF, Musitu G, Riquelme E, Riquelme P.

Span J Psychol. 2011 Nov;14(2):648-58.

PMID:
22059311
17.

Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy.

Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV, Wistuba II.

Cancer Res. 2011 Aug 15;71(16):5512-21. doi: 10.1158/0008-5472.CAN-10-2614. Epub 2011 Jul 1.

18.

[Implementing a quality management system according to iso model in a Microbiology laboratory].

Riquelme E, Lorente S, Crespo MD.

Enferm Infecc Microbiol Clin. 2011 Jan;29(1):72-3. doi: 10.1016/j.eimc.2010.04.018. Epub 2010 Dec 28. Spanish. No abstract available.

PMID:
21193248
19.

A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.

Carvajal CA, Stehr CB, González PA, Riquelme EM, Montero T, Santos MJ, Kalergis AM, Fardella CE.

J Endocrinol Invest. 2011 Feb;34(2):140-4. doi: 10.3275/7171. Epub 2010 Jul 13.

PMID:
20634641
20.

Emerging evidence for the role of neurotransmitters in the modulation of T cell responses to cognate ligands.

Pacheco R, Riquelme E, Kalergis AM.

Cent Nerv Syst Agents Med Chem. 2010 Mar;10(1):65-83. Review.

PMID:
20236043
21.

T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC.

Carreño LJ, Riquelme EM, González PA, Espagnolle N, Riedel CA, Valitutti S, Kalergis AM.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):210-5. doi: 10.1073/pnas.0911258107. Epub 2009 Dec 14.

22.

The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity.

Riquelme E, Carreño LJ, González PA, Kalergis AM.

Eur J Immunol. 2009 Aug;39(8):2259-69. doi: 10.1002/eji.200939341.

23.

NMDA receptors mediate an early up-regulation of brain-derived neurotrophic factor expression in substantia nigra in a rat model of presymptomatic Parkinson's disease.

Bustos G, Abarca J, Bustos V, Riquelme E, Noriega V, Moya C, Campusano J.

J Neurosci Res. 2009 Aug 1;87(10):2308-18. doi: 10.1002/jnr.22063.

PMID:
19326433
24.

A novel adrenocorticotropin receptor mutation alters its structure and function, causing familial glucocorticoid deficiency.

Artigas RA, Gonzalez A, Riquelme E, Carvajal CA, Cattani A, Martínez-Aguayo A, Kalergis AM, Pérez-Acle T, Fardella CE.

J Clin Endocrinol Metab. 2008 Aug;93(8):3097-105. doi: 10.1210/jc.2008-0048. Epub 2008 May 20.

PMID:
18492762
25.

[Acute Streptococcus suis meningitis in a woman working in a meat market].

Riquelme E, Escribano E, Blanch JJ, Crespo MD.

Enferm Infecc Microbiol Clin. 2008 Apr;26(4):256-7. Spanish. No abstract available.

PMID:
18381047
26.

Mismatch repair expression in testicular cancer predicts recurrence and survival.

Velasco A, Corvalan A, Wistuba II, Riquelme E, Chuaqui R, Majerson A, Leach FS.

Int J Cancer. 2008 Apr 15;122(8):1774-7.

27.

Analytical detection of immunoglobulin heavy chain gene rearrangements in gastric lymphoid infiltrates by peak area analysis of the melting curve in the LightCycler System.

Retamales E, Rodriguez L, Guzman L, Aguayo F, Palma M, Backhouse C, Argandona J, Riquelme E, Corvalan A.

J Mol Diagn. 2007 Jul;9(3):351-7.

28.

A polymorphic GT short tandem repeat affecting beta-ENaC mRNA expression is associated with low renin essential hypertension.

González AA, Carvajal CA, Riquelme E, Krall PM, Munoz CR, Mosso LM, Kalergis AM, Fardella CE.

Am J Hypertens. 2007 Jul;20(7):800-6.

PMID:
17586416
29.

[Seroepidemiology of Coxiella burnetii infection among blood donors in Albacete].

Bartolomé J, Riquelme E, Hernández-Pérez N, García-Ruiz S, Luján R, Lorente S, Medrano-Callejas R, Crespo MD.

Enferm Infecc Microbiol Clin. 2007 Jun-Jul;25(6):382-6. Spanish.

PMID:
17583651
30.

Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma.

Riquelme E, Tang M, Baez S, Diaz A, Pruyas M, Wistuba II, Corvalan A.

Cancer Lett. 2007 May 18;250(1):100-6. Epub 2006 Nov 7.

PMID:
17084965
31.

Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence.

Velasco A, Riquelme E, Schultz M, Wistuba II, Villarroel L, Koh MS, Leach FS.

Cancer Biol Ther. 2004 Nov;3(11):1152-8; discussion 1159-61. Epub 2004 Nov 9.

PMID:
15492498
32.

Mismatch repair gene expression and genetic instability in testicular germ cell tumor.

Velasco A, Riquelme E, Schultz M, Wistuba II, Villarroel L, Pizarro J, Berlin A, Ittmann M, Koh MS, Leach FS.

Cancer Biol Ther. 2004 Oct;3(10):977-82. Epub 2004 Oct 2.

PMID:
15467433
33.

Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis.

Takahashi T, Shivapurkar N, Riquelme E, Shigematsu H, Reddy J, Suzuki M, Miyajima K, Zhou X, Bekele BN, Gazdar AF, Wistuba II.

Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6126-33.

34.

Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma.

Tang M, Baez S, Pruyas M, Diaz A, Calvo A, Riquelme E, Wistuba II.

Clin Cancer Res. 2004 Feb 1;10(3):1041-6.

35.

Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma.

Wistuba II, Ashfaq R, Maitra A, Alvarez H, Riquelme E, Gazdar AF.

Am J Pathol. 2002 Jun;160(6):2073-9.

36.

[Importance and characteristics of burns in a pediatric emergency service].

Salas I, Silva C, Ruiz F, Rubio E, Astorquiza G, Perales C, Riquelme E, Sepúlveda J.

Rev Chil Pediatr. 1989 Nov-Dec;60(6):362-7. Spanish.

PMID:
2520844
37.

[Psychotherapy for children. Theoretical and practical approach].

Riquelme E.

Neurol Neurocir Psiquiatr. 1977;18(2-3):167-72. Spanish.

PMID:
917202

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