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Year Number of Results
2004 1
2005 1
2009 1
2010 1
2012 2
2013 1
2014 2
2015 2
2016 1
2017 2
2018 1
2019 3
2020 2
2021 2
2022 4
2023 1
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24 results

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Page 1
RIOX1-demethylated cGAS regulates ionizing radiation-elicited DNA repair.
Xiao Y, Li J, Liao X, He Y, He T, Yang C, Jiang L, Jeon SM, Lee JH, Chen Y, Liu R, Chen Q. Xiao Y, et al. Bone Res. 2022 Feb 24;10(1):19. doi: 10.1038/s41413-022-00194-0. Bone Res. 2022. PMID: 35210392 Free PMC article.
Here, we report that loss of the demethylase ribosomal oxygenase 1 (RIOX1) restores cell proliferation and reduces cell death after exposure to ionizing radiation. ...High expression of RIOX1 maintains cGAS K491me at a low level, which impedes HR repair and reduces …
Here, we report that loss of the demethylase ribosomal oxygenase 1 (RIOX1) restores cell proliferation and reduces cell death after e …
Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice.
Chen Q, Sinha KM, de Crombrugghe B, Krahe R. Chen Q, et al. J Osteoporos. 2023 Jan 10;2023:8998556. doi: 10.1155/2023/8998556. eCollection 2023. J Osteoporos. 2023. PMID: 36660551 Free PMC article.
In previous study, we showed that nucleolar protein 66 (NO66) is a chromatin modifier and negatively regulates Osterix activity as well as mesenchymal progenitor differentiation. Genetic ablation of the NO66 (RIOX1) gene in cells of the Prx1-expressing mesenchymal lineage …
In previous study, we showed that nucleolar protein 66 (NO66) is a chromatin modifier and negatively regulates Osterix activity as well as m …
The small members of the JMJD protein family: Enzymatic jewels or jinxes?
Oh S, Shin S, Janknecht R. Oh S, et al. Biochim Biophys Acta Rev Cancer. 2019 Apr;1871(2):406-418. doi: 10.1016/j.bbcan.2019.04.002. Epub 2019 Apr 26. Biochim Biophys Acta Rev Cancer. 2019. PMID: 31034925 Free PMC article. Review.
Here, we discuss the ten human small JMJD proteins (HIF1AN, HSPBAP1, JMJD4, JMJD5, JMJD6, JMJD7, JMJD8, RIOX1, RIOX2, TYW5) and their diverse physiological functions. In particular, we focus on the roles of these small JMJD proteins in cancer and other maladies and how the …
Here, we discuss the ten human small JMJD proteins (HIF1AN, HSPBAP1, JMJD4, JMJD5, JMJD6, JMJD7, JMJD8, RIOX1, RIOX2, TYW5) and their …
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution.
Bräuer KE, Brockers K, Moneer J, Feuchtinger A, Wollscheid-Lengeling E, Lengeling A, Wolf A. Bräuer KE, et al. BMC Evol Biol. 2018 Jun 19;18(1):96. doi: 10.1186/s12862-018-1215-0. BMC Evol Biol. 2018. PMID: 29914368 Free PMC article.
Our genomic and phylogenetic analyses revealed that Arthropoda, Annelida, Nematoda and Mollusca lack the Riox2 gene, although in the early phylum Cnidaria both genes, Riox1 and Riox2, are present and expressed. Riox1 is an intronless single-exon-gene in several spec …
Our genomic and phylogenetic analyses revealed that Arthropoda, Annelida, Nematoda and Mollusca lack the Riox2 gene, although in the early p …
Weighted Correlation Network Analysis of Cancer Stem Cell-Related Prognostic Biomarkers in Esophageal Squamous Cell Carcinoma.
Zhao M, Jin X, Chen Z, Zhang H, Zhan C, Wang H, Wang Q. Zhao M, et al. Technol Cancer Res Treat. 2022 Jan-Dec;21:15330338221117003. doi: 10.1177/15330338221117003. Technol Cancer Res Treat. 2022. PMID: 35899307 Free PMC article.
Seven stemness-related genes were identified by WGCNA and LASSO regression, based on which a risk-predicted score model was constructed. Among them, CST1, CILP, PITX2, F2RL2, and RIOX1 were favorable for OS, which were adverse for DPP4 and ZFHX4 in the GSE53625 dataset. Ho …
Seven stemness-related genes were identified by WGCNA and LASSO regression, based on which a risk-predicted score model was constructed. Amo …
Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle.
Häfliger IM, Spengeler M, Seefried FR, Drögemüller C. Häfliger IM, et al. Sci Rep. 2022 Mar 31;12(1):5435. doi: 10.1038/s41598-022-09403-6. Sci Rep. 2022. PMID: 35361830 Free PMC article.
For two previously reported deficient homozygous haplotypes that show negative associations to female fertility traits, we propose candidate causative loss-of-function variants: the HH13-related KIR2DS1:p.Gln159* nonsense variant and the HH21-related NOTCH3:p.Cys44del deletion. I …
For two previously reported deficient homozygous haplotypes that show negative associations to female fertility traits, we propose candidate …
Genome-wide identification, evolution of histone lysine demethylases (KDM) genes and their expression during gonadal development in Nile tilapia.
Qin Z, Li Z, Yang S, Wang F, Gao T, Tao W, Zhou L, Wang D, Sun L. Qin Z, et al. Comp Biochem Physiol B Biochem Mol Biol. 2022 Jan;257:110674. doi: 10.1016/j.cbpb.2021.110674. Epub 2021 Oct 6. Comp Biochem Physiol B Biochem Mol Biol. 2022. PMID: 34624518
Importantly, from transcriptome data, qRT-PCR and fluorescence in situ hybridization during sex reversal, genes with higher expression in ovary than testis, such as kdm1b and two JmjC-only subfamily members hspbap1 and riox1, were downregulated, while other genes, such as …
Importantly, from transcriptome data, qRT-PCR and fluorescence in situ hybridization during sex reversal, genes with higher expression in ov …
Mechanisms Regulating Muscle Protein Synthesis in CKD.
Zhang L, Chen Q, Chen Z, Wang Y, Gamboa JL, Ikizler TA, Garibotto G, Mitch WE. Zhang L, et al. J Am Soc Nephrol. 2020 Nov;31(11):2573-2587. doi: 10.1681/ASN.2019121277. Epub 2020 Aug 6. J Am Soc Nephrol. 2020. PMID: 32764136 Free PMC article.
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
Ge W, Wolf A, Feng T, Ho CH, Sekirnik R, Zayer A, Granatino N, Cockman ME, Loenarz C, Loik ND, Hardy AP, Claridge TDW, Hamed RB, Chowdhury R, Gong L, Robinson CV, Trudgian DC, Jiang M, Mackeen MM, Mccullagh JS, Gordiyenko Y, Thalhammer A, Yamamoto A, Yang M, Liu-Yi P, Zhang Z, Schmidt-Zachmann M, Kessler BM, Ratcliffe PJ, Preston GM, Coleman ML, Schofield CJ. Ge W, et al. Nat Chem Biol. 2012 Dec;8(12):960-962. doi: 10.1038/nchembio.1093. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103944 Free PMC article.
24 results