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Items: 20

1.

Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma.

Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ.

Cancer Res. 2019 Oct 1;79(19):5074-5087. doi: 10.1158/0008-5472.CAN-19-0244. Epub 2019 Aug 15.

PMID:
31416844
2.

A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells.

Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ.

BMC Genomics. 2019 Jun 17;20(1):497. doi: 10.1186/s12864-019-5888-6.

3.

Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.

Blanc V, Xie Y, Kennedy S, Riordan JD, Rubin DC, Madison BB, Mills JC, Nadeau JH, Davidson NO.

RNA. 2019 Jan;25(1):70-81. doi: 10.1261/rna.068395.118. Epub 2018 Oct 11.

PMID:
30309881
4.

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.

Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML.

Cell Rep. 2018 Jan 30;22(5):1211-1224. doi: 10.1016/j.celrep.2018.01.017.

5.

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.

Tschida BR, Temiz NA, Kuka TP, Lee LA, Riordan JD, Tierrablanca CA, Hullsiek R, Wagner S, Hudson WA, Linden MA, Amin K, Beckmann PJ, Heuer RA, Sarver AL, Yang JD, Roberts LR, Nadeau JH, Dupuy AJ, Keng VW, Largaespada DA.

Cancer Res. 2017 Dec 1;77(23):6576-6588. doi: 10.1158/0008-5472.CAN-17-2281. Epub 2017 Oct 9.

6.

Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.

Riordan JD, Feddersen CR, Tschida BR, Beckmann PJ, Keng VW, Linden MA, Amin K, Stipp CS, Largaespada DA, Dupuy AJ.

Hepatology. 2018 Mar;67(3):924-939. doi: 10.1002/hep.29565. Epub 2018 Jan 26.

7.

From Peas to Disease: Modifier Genes, Network Resilience, and the Genetics of Health.

Riordan JD, Nadeau JH.

Am J Hum Genet. 2017 Aug 3;101(2):177-191. doi: 10.1016/j.ajhg.2017.06.004. Review.

8.

Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.

Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4951-E4960. doi: 10.1073/pnas.1702723114. Epub 2017 Jun 5.

9.

Re: Srivastava A, Carter BJ; AAV Infection: Protection from Cancer; Hum Gene Ther 2017;28:323-327; DOI: 10.1089/hum.2016.147.

Riordan JD.

Hum Gene Ther. 2017 May;28(5):375-376. doi: 10.1089/hum.2017.045. No abstract available.

PMID:
28335621
10.

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens.

Temiz NA, Moriarity BS, Wolf NK, Riordan JD, Dupuy AJ, Largaespada DA, Sarver AL.

Genome Res. 2016 Jan;26(1):119-29. doi: 10.1101/gr.188649.114. Epub 2015 Nov 9.

11.

Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome.

Sinasac DS, Riordan JD, Spiezio SH, Yandell BS, Croniger CM, Nadeau JH.

Int J Obes (Lond). 2016 Feb;40(2):346-55. doi: 10.1038/ijo.2015.184. Epub 2015 Sep 18.

PMID:
26381349
12.

A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition.

Smith RP, Riordan JD, Feddersen CR, Dupuy AJ.

Hum Gene Ther. 2015 Jun;26(6):377-85. doi: 10.1089/hum.2014.123.

13.

Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens.

Riordan JD, Drury LJ, Smith RP, Brett BT, Rogers LM, Scheetz TE, Dupuy AJ.

BMC Genomics. 2014 Dec 19;15:1150. doi: 10.1186/1471-2164-15-1150.

14.

Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse.

Riordan JD, Nadeau JH.

Mamm Genome. 2014 Oct;25(9-10):473-86. doi: 10.1007/s00335-014-9521-3. Epub 2014 May 7. Review.

15.

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis.

DeZwaan-McCabe D, Riordan JD, Arensdorf AM, Icardi MS, Dupuy AJ, Rutkowski DT.

PLoS Genet. 2013;9(12):e1003937. doi: 10.1371/journal.pgen.1003937. Epub 2013 Dec 19.

16.

Domesticated transposable element gene products in human cancer.

Riordan JD, Dupuy AJ.

Mob Genet Elements. 2013 Sep 1;3(5):e26693. Epub 2013 Oct 14.

17.

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.

Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM, Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ.

PLoS Genet. 2013 Apr;9(4):e1003441. doi: 10.1371/journal.pgen.1003441. Epub 2013 Apr 4.

18.

Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer.

Rogers LM, Riordan JD, Swick BL, Meyerholz DK, Dupuy AJ.

J Invest Dermatol. 2013 Jul;133(7):1863-9. doi: 10.1038/jid.2013.77. Epub 2013 Feb 20.

19.

Terahertz tuning of whispering gallery modes in a PDMS stand-alone, stretchable microsphere.

Madugani R, Yang Y, Ward JM, Riordan JD, Coppola S, Vespini V, Grilli S, Finizio A, Ferraro P, Nic Chormaic S.

Opt Lett. 2012 Nov 15;37(22):4762-4.

PMID:
23164905
20.

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, Llovet JM, Largaespada DA.

Hepatology. 2013 Jan;57(1):120-30. doi: 10.1002/hep.26004. Epub 2012 Oct 19.

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