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Items: 8


Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and Therapeutics.

Riobo-Del Galdo NA, Lara Montero Á, Wertheimer EV.

Cells. 2019 Apr 25;8(4). pii: E375. doi: 10.3390/cells8040375. Review.


Overexpression of Desmoglein 2 in a Mouse Model of Gorlin Syndrome Enhances Spontaneous Basal Cell Carcinoma Formation through STAT3-Mediated Gli1 Expression.

Brennan-Crispi DM, Overmiller AM, Tamayo-Orrego L, Marous MR, Sahu J, McGuinn KP, Cooper F, Georgiou IC, Frankfurter M, Salas-Alanis JC, Charron F, Millar SE, Mahoney MG, Riobo-Del Galdo NA.

J Invest Dermatol. 2019 Feb;139(2):300-307. doi: 10.1016/j.jid.2018.09.009. Epub 2018 Oct 3.


Activation of the Gi protein-RHOA axis by non-canonical Hedgehog signaling is independent of primary cilia.

Ho Wei L, Arastoo M, Georgiou I, Manning DR, Riobo-Del Galdo NA.

PLoS One. 2018 Aug 27;13(8):e0203170. doi: 10.1371/journal.pone.0203170. eCollection 2018.


Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes and prolongs cardiac action potential duration.

Cheng L, Al-Owais M, Covarrubias ML, Koch WJ, Manning DR, Peers C, Riobo-Del Galdo NA.

J Biol Chem. 2018 Jul 13;293(28):11022-11032. doi: 10.1074/jbc.RA118.001989. Epub 2018 May 25.


Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G13.

Guo X, Riobo-Del Galdo NA, Kim EJ, Grant GR, Manning DR.

PLoS One. 2018 May 15;13(5):e0197442. doi: 10.1371/journal.pone.0197442. eCollection 2018.


Enhancement of Cutaneous Wound Healing by Dsg2 Augmentation of uPAR Secretion.

Cooper F, Overmiller AM, Loder A, Brennan-Crispi DM, McGuinn KP, Marous MR, Freeman TA, Riobo-Del Galdo NA, Siracusa LD, Wahl JK 3rd, Mahoney MG.

J Invest Dermatol. 2018 Nov;138(11):2470-2479. doi: 10.1016/j.jid.2018.04.024. Epub 2018 May 9.


Autophagic Flux Is Regulated by Interaction Between the C-terminal Domain of PATCHED1 and ATG101.

Chen X, Morales-Alcala CC, Riobo-Del Galdo NA.

Mol Cancer Res. 2018 May;16(5):909-919. doi: 10.1158/1541-7786.MCR-17-0597. Epub 2018 Feb 16.


The Prognostic Significance of the Hedgehog Signaling Pathway in Colorectal Cancer.

Papadopoulos V, Tsapakidis K, Riobo Del Galdo NA, Papandreou CN, Del Galdo F, Anthoney A, Sakellaridis N, Dimas K, Kamposioras K.

Clin Colorectal Cancer. 2016 Jun;15(2):116-27. doi: 10.1016/j.clcc.2016.02.010. Epub 2016 Feb 16. Review.


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