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Items: 1 to 50 of 80

1.

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs.

Altai M, Leitao CD, Rinne SS, Vorobyeva A, Atterby C, Ståhl S, Tolmachev V, Löfblom J, Orlova A.

Cells. 2018 Oct 11;7(10). pii: E164. doi: 10.3390/cells7100164.

2.

Reply to: Extent of Overuse of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease.

Rinne ST, Wiener RS, Chen Y, Rise P, Udris E, Feemster LC, Au DH.

Am J Respir Crit Care Med. 2018 Oct 2. doi: 10.1164/rccm.201809-1732LE. [Epub ahead of print] No abstract available.

PMID:
30278144
3.

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model.

Mitran B, Güler R, Roche FP, Lindström E, Selvaraju RK, Fleetwood F, Rinne SS, Claesson-Welsh L, Tolmachev V, Ståhl S, Orlova A, Löfblom J.

Theranostics. 2018 Aug 7;8(16):4462-4476. doi: 10.7150/thno.24395. eCollection 2018.

4.

In Vitro Analyses of Novel HCN4 Gene Mutations.

Möller M, Silbernagel N, Wrobel E, Stallmayer B, Amedonu E, Rinné S, Peischard S, Meuth SG, Wünsch B, Strutz-Seebohm N, Decher N, Schulze-Bahr E, Seebohm G.

Cell Physiol Biochem. 2018;49(3):1197-1207. doi: 10.1159/000493301. Epub 2018 Sep 7.

5.

Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab.

Orlova A, Bass TZ, Rinne SS, Leitao CD, Rosestedt M, Atterby C, Gudmundsdotter L, Frejd FY, Löfblom J, Tolmachev V, Ståhl S.

Mol Pharm. 2018 Aug 6;15(8):3394-3403. doi: 10.1021/acs.molpharmaceut.8b00393. Epub 2018 Jul 25.

PMID:
29995421
6.

Impact of Guideline Changes on Indications for Inhaled Corticosteroids Among Veterans with COPD.

Rinne ST, Wiener RS, Chen Y, Rise P, Udris E, Feemster LC, Au DH.

Am J Respir Crit Care Med. 2018 Jul 3. doi: 10.1164/rccm.201803-0554LE. [Epub ahead of print]

PMID:
29969041
7.

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy.

Vorobyeva A, Westerlund K, Mitran B, Altai M, Rinne S, Sörensen J, Orlova A, Tolmachev V, Karlström AE.

Sci Rep. 2018 Jun 25;8(1):9643. doi: 10.1038/s41598-018-27886-0.

8.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.

Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N.

FASEB J. 2018 Jun 7:fj201800246R. doi: 10.1096/fj.201800246R. [Epub ahead of print]

PMID:
29879376
9.

Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish.

Pott A, Bock S, Berger IM, Frese K, Dahme T, Keßler M, Rinné S, Decher N, Just S, Rottbauer W.

J Mol Cell Cardiol. 2018 Jul;120:42-52. doi: 10.1016/j.yjmcc.2018.05.005. Epub 2018 May 8.

PMID:
29750993
10.

Management of Comorbid Chronic Obstructive Pulmonary Disease and Cardiovascular Disease. Moving Past the Agony of the β-Receptor Debate.

Rinne ST.

Ann Am Thorac Soc. 2018 May;15(5):558-559. doi: 10.1513/AnnalsATS.201802-090ED. No abstract available.

PMID:
29714105
11.

Calcium-activated SK potassium channels are key modulators of the pacemaker frequency in locus coeruleus neurons.

Matschke LA, Rinné S, Snutch TP, Oertel WH, Dolga AM, Decher N.

Mol Cell Neurosci. 2018 Apr;88:330-341. doi: 10.1016/j.mcn.2018.03.002. Epub 2018 Mar 8.

PMID:
29524627
12.

Phosphodiesterase-5 Inhibitor Therapy for Pulmonary Hypertension in the United States. Actual versus Recommended Use.

Kim D, Lee KM, Freiman MR, Powell WR, Klings ES, Rinne ST, Miller DR, Rose AJ, Wiener RS.

Ann Am Thorac Soc. 2018 Jun;15(6):693-701. doi: 10.1513/AnnalsATS.201710-762OC.

PMID:
29485908
13.

Hospital Administrators' Perspectives on Physician Engagement: A Qualitative Study.

Rinne ST, Rinne TJ, Olsen K, Wiener RS, Balcezak TJ, Dardani W, Elwy R.

J Hosp Med. 2018 Mar 1;13(3):179-181. doi: 10.12788/jhm.2880. Epub 2017 Nov 22.

PMID:
29186211
14.

Stress-Kinase Regulation of TASK-1 and TASK-3.

Rinné S, Kiper AK, Schmidt C, Ortiz-Bonnin B, Zwiener S, Seebohm G, Decher N.

Cell Physiol Biochem. 2017;44(3):1024-1037. doi: 10.1159/000485402. Epub 2017 Nov 27.

15.

Association between length of stay and readmission for COPD.

Rinne ST, Graves MC, Bastian LA, Lindenauer PK, Wong ES, Hebert PL, Liu CF.

Am J Manag Care. 2017 Aug 1;23(8):e253-e258.

16.

Evaluation of a radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression.

Rosestedt M, Andersson KG, Mitran B, Rinne SS, Tolmachev V, Löfblom J, Orlova A, Ståhl S.

Int J Oncol. 2017 Dec;51(6):1765-1774. doi: 10.3892/ijo.2017.4152. Epub 2017 Oct 11.

PMID:
29039474
17.

Hospital Variation in Do-Not-Resuscitate Orders and End-of-Life Healthcare Use in the United States.

Walkey AJ, Barnato AE, Rinne ST, Cooke CR, Shieh MS, Pekow PS, Lindenauer PK.

Ann Am Thorac Soc. 2017 Sep;14(9):1485-1489. doi: 10.1513/AnnalsATS.201704-303RL. No abstract available.

18.

Acetylcholine-dependent upregulation of TASK-1 channels in thalamic interneurons by a smooth muscle-like signalling pathway.

Leist M, Rinné S, Datunashvili M, Aissaoui A, Pape HC, Decher N, Meuth SG, Budde T.

J Physiol. 2017 Sep 1;595(17):5875-5893. doi: 10.1113/JP274527. Epub 2017 Aug 3.

19.

Implementation of guideline-based therapy for chronic obstructive pulmonary disease: Differences between men and women veterans.

Rinne ST, Elwy AR, Liu CF, Wiener RS, Thayer L, Gerity A, Bastian LA.

Chron Respir Dis. 2017 Nov;14(4):385-391. doi: 10.1177/1479972317702141. Epub 2017 Jun 15.

20.

Stretch-activated potassium currents in the heart: Focus on TREK-1 and arrhythmias.

Decher N, Kiper AK, Rinné S.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):223-232. doi: 10.1016/j.pbiomolbio.2017.05.005. Epub 2017 May 16. Review.

PMID:
28526352
21.

Side Fenestrations Provide an "Anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels.

Ramírez D, Arévalo B, Martínez G, Rinné S, Sepúlveda FV, Decher N, González W.

Mol Pharm. 2017 Jul 3;14(7):2197-2208. doi: 10.1021/acs.molpharmaceut.7b00005. Epub 2017 May 30.

PMID:
28494157
22.

Organizational Practices Affecting Chronic Obstructive Pulmonary Disease Readmissions.

Rinne ST, Hebert PL, Wong ES, Au DH, Bastian LA, Nembhard IM, Neely EL, Sulc CA, Liu CF.

Am J Respir Crit Care Med. 2017 May 1;195(9):1269-1272. doi: 10.1164/rccm.201609-1783LE. No abstract available.

PMID:
28459333
23.

Impact of Multisystem Health Care on Readmission and Follow-up Among Veterans Hospitalized for Chronic Obstructive Pulmonary Disease.

Rinne ST, Elwy AR, Bastian LA, Wong ES, Wiener RS, Liu CF.

Med Care. 2017 Jul;55 Suppl 7 Suppl 1:S20-S25. doi: 10.1097/MLR.0000000000000708.

PMID:
28288076
24.

Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.

Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinné S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskämper J, Kohl P, Just S, González W, Baukrowitz T, Stallmeyer B, Schulze-Bahr E.

EMBO Mol Med. 2017 Apr;9(4):403-414. doi: 10.15252/emmm.201606690.

25.

A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.

Stallmeyer B, Kuß J, Kotthoff S, Zumhagen S, Vowinkel K, Rinné S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E.

Circ Res. 2017 May 12;120(10):e33-e44. doi: 10.1161/CIRCRESAHA.116.310112. Epub 2017 Feb 20.

PMID:
28219978
26.

Chronic Obstructive Pulmonary Disease Readmissions and Other Measures of Hospital Quality.

Rinne ST, Castaneda J, Lindenauer PK, Cleary PD, Paz HL, Gomez JL.

Am J Respir Crit Care Med. 2017 Jul 1;196(1):47-55. doi: 10.1164/rccm.201609-1944OC.

27.

Hospital Distance and Readmissions Among VA-Medicare Dual-Enrolled Veterans.

Wong ES, Rinne ST, Hebert PL, Cook MA, Liu CF.

J Rural Health. 2016 Sep;32(4):377-386. doi: 10.1111/jrh.12191. Epub 2016 Jul 18.

PMID:
27424850
28.

Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: identification of novel LQTS3 and BrS mutations.

Ortiz-Bonnin B, Rinné S, Moss R, Streit AK, Scharf M, Richter K, Stöber A, Pfeufer A, Seemann G, Kääb S, Beckmann BM, Decher N.

Pflugers Arch. 2016 Aug;468(8):1375-87. doi: 10.1007/s00424-016-1844-3. Epub 2016 Jun 11.

PMID:
27287068
29.

Methods for Measuring Racial Differences in Hospitals Outcomes Attributable to Disparities in Use of High-Quality Hospital Care.

Hebert PL, Howell EA, Wong ES, Hernandez SE, Rinne ST, Sulc CA, Neely EL, Liu CF.

Health Serv Res. 2017 Apr;52(2):826-848. doi: 10.1111/1475-6773.12514. Epub 2016 Jun 3.

30.

Organizational structure for chronic heart failure and chronic obstructive pulmonary disease.

Rinne ST, Liu CF, Wong ES, Hebert PL, Heidenreich P, Bastian LA, Au DH.

Am J Manag Care. 2016 Mar 1;22(3):e82-7.

31.

Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.

Goldstein M, Rinné S, Kiper AK, Ramírez D, Netter MF, Bustos D, Ortiz-Bonnin B, González W, Decher N.

Sci Rep. 2016 Jan 22;6:19492. doi: 10.1038/srep19492.

32.

POPDC1(S201F) causes muscular dystrophy and arrhythmia by affecting protein trafficking.

Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T, Ferlini A.

J Clin Invest. 2016 Jan;126(1):239-53. doi: 10.1172/JCI79562. Epub 2015 Dec 7.

33.

An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities.

Wemhöner K, Kanyshkova T, Silbernagel N, Fernandez-Orth J, Bittner S, Kiper AK, Rinné S, Netter MF, Meuth SG, Budde T, Decher N.

Front Mol Neurosci. 2015 Nov 3;8:63. doi: 10.3389/fnmol.2015.00063. eCollection 2015.

34.

A concerted action of L- and T-type Ca(2+) channels regulates locus coeruleus pacemaking.

Matschke LA, Bertoune M, Roeper J, Snutch TP, Oertel WH, Rinné S, Decher N.

Mol Cell Neurosci. 2015 Sep;68:293-302. doi: 10.1016/j.mcn.2015.08.012. Epub 2015 Aug 25.

PMID:
26319746
35.

Thiazolidinediones are associated with a reduced risk of COPD exacerbations.

Rinne ST, Liu CF, Feemster LC, Collins BF, Bryson CL, O'Riordan TG, Au DH.

Int J Chron Obstruct Pulmon Dis. 2015 Aug 10;10:1591-7. doi: 10.2147/COPD.S82643. eCollection 2015.

36.

Weekend Discharges and Length of Stay Among Veterans Admitted for Chronic Obstructive Pulmonary Disease.

Rinne ST, Wong ES, Hebert PL, Au DH, Lindenauer PK, Neely EL, Sulc CA, Liu CF.

Med Care. 2015 Sep;53(9):753-7. doi: 10.1097/MLR.0000000000000395.

PMID:
26147865
37.

Survey nonresponders incurred higher medical utilization and lower medication adherence.

Rinne ST, Wong ES, Lemon JM, Perkins M, Bryson CL, Liu CF.

Am J Manag Care. 2015 Jan 1;21(1):e1-8.

38.

TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes.

Rinné S, Kiper AK, Schlichthörl G, Dittmann S, Netter MF, Limberg SH, Silbernagel N, Zuzarte M, Moosdorf R, Wulf H, Schulze-Bahr E, Rolfes C, Decher N.

J Mol Cell Cardiol. 2015 Apr;81:71-80. doi: 10.1016/j.yjmcc.2015.01.017. Epub 2015 Feb 2.

PMID:
25655935
39.

Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.

Wemhöner K, Friedrich C, Stallmeyer B, Coffey AJ, Grace A, Zumhagen S, Seebohm G, Ortiz-Bonnin B, Rinné S, Sachse FB, Schulze-Bahr E, Decher N.

J Mol Cell Cardiol. 2015 Mar;80:186-95. doi: 10.1016/j.yjmcc.2015.01.002. Epub 2015 Jan 26.

PMID:
25633834
40.

Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?

Kiper AK, Rinné S, Rolfes C, Ramírez D, Seebohm G, Netter MF, González W, Decher N.

Pflugers Arch. 2015 May;467(5):1081-90. doi: 10.1007/s00424-014-1665-1. Epub 2014 Dec 17.

PMID:
25511502
41.

The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.

Decher N, Kiper AK, Rolfes C, Schulze-Bahr E, Rinné S.

Pflugers Arch. 2015 May;467(5):1055-67. doi: 10.1007/s00424-014-1637-5. Epub 2014 Nov 19. Review.

PMID:
25404566
42.

RNA editing in the central cavity as a mechanism to regulate surface expression of the voltage-gated potassium channel Kv1.1.

Streit AK, Matschke LA, Dolga AM, Rinné S, Decher N.

J Biol Chem. 2014 Sep 26;289(39):26762-71. doi: 10.1074/jbc.M113.545731. Epub 2014 Aug 6.

43.

Factors predictive of airflow obstruction among veterans with presumed empirical diagnosis and treatment of COPD.

Collins BF, Feemster LC, Rinne ST, Au DH.

Chest. 2015 Feb;147(2):369-376. doi: 10.1378/chest.14-0672.

44.

Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study.

Rinne ST, Feemster LC, Collins BF, Au DH, Perkins M, Bryson CL, O'Riordan TG, Liu CF.

Allergy Asthma Clin Immunol. 2014 Jul 3;10(1):34. doi: 10.1186/1710-1492-10-34. eCollection 2014.

45.

Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.

Friedrich C, Rinné S, Zumhagen S, Kiper AK, Silbernagel N, Netter MF, Stallmeyer B, Schulze-Bahr E, Decher N.

EMBO Mol Med. 2014 Jul;6(7):937-51. doi: 10.15252/emmm.201303783.

46.

Cooperative endocytosis of the endosomal SNARE protein syntaxin-8 and the potassium channel TASK-1.

Renigunta V, Fischer T, Zuzarte M, Kling S, Zou X, Siebert K, Limberg MM, Rinné S, Decher N, Schlichthörl G, Daut J.

Mol Biol Cell. 2014 Jun 15;25(12):1877-91. doi: 10.1091/mbc.E13-10-0592. Epub 2014 Apr 17.

47.

A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels.

Rinné S, Renigunta V, Schlichthörl G, Zuzarte M, Bittner S, Meuth SG, Decher N, Daut J, Preisig-Müller R.

Pflugers Arch. 2014 Aug;466(8):1559-70. doi: 10.1007/s00424-013-1384-z. Epub 2013 Nov 7.

PMID:
24196565
48.

Side pockets provide the basis for a new mechanism of Kv channel-specific inhibition.

Marzian S, Stansfeld PJ, Rapedius M, Rinné S, Nematian-Ardestani E, Abbruzzese JL, Steinmeyer K, Sansom MS, Sanguinetti MC, Baukrowitz T, Decher N.

Nat Chem Biol. 2013 Aug;9(8):507-13. doi: 10.1038/nchembio.1271. Epub 2013 Jun 2.

49.

Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype.

Limberg MM, Zumhagen S, Netter MF, Coffey AJ, Grace A, Rogers J, Böckelmann D, Rinné S, Stallmeyer B, Decher N, Schulze-Bahr E.

Basic Res Cardiol. 2013 May;108(3):353. doi: 10.1007/s00395-013-0353-1. Epub 2013 May 5.

PMID:
23644778
50.

Soluble polysialylated NCAM: a novel player of the innate immune system in the lung.

Ulm C, Saffarzadeh M, Mahavadi P, Müller S, Prem G, Saboor F, Simon P, Middendorff R, Geyer H, Henneke I, Bayer N, Rinné S, Lütteke T, Böttcher-Friebertshäuser E, Gerardy-Schahn R, Schwarzer D, Mühlenhoff M, Preissner KT, Günther A, Geyer R, Galuska SP.

Cell Mol Life Sci. 2013 Oct;70(19):3695-708. doi: 10.1007/s00018-013-1342-0. Epub 2013 Apr 26.

PMID:
23619613

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