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Items: 1 to 50 of 76

1.

In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose.

Krishnan V, Clark R, Chekmareva M, Johnson A, George S, Shaw P, Seewaldt V, Rinker-Schaeffer C.

J Vis Exp. 2015 Oct 14;(105):e52721. doi: 10.3791/52721.

2.

SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer.

Li G, Ci W, Karmakar S, Chen K, Dhar R, Fan Z, Guo Z, Zhang J, Ke Y, Wang L, Zhuang M, Hu S, Li X, Zhou L, Li X, Calabrese MF, Watson ER, Prasad SM, Rinker-Schaeffer C, Eggener SE, Stricker T, Tian Y, Schulman BA, Liu J, White KP.

Cancer Cell. 2014 Apr 14;25(4):455-68. doi: 10.1016/j.ccr.2014.02.007. Epub 2014 Mar 20.

3.

Milky spots promote ovarian cancer metastatic colonization of peritoneal adipose in experimental models.

Clark R, Krishnan V, Schoof M, Rodriguez I, Theriault B, Chekmareva M, Rinker-Schaeffer C.

Am J Pathol. 2013 Aug;183(2):576-91. doi: 10.1016/j.ajpath.2013.04.023.

4.

Flexible peritoneal windows for quantitative fluorescence and bioluminescence preclinical imaging.

Souris JS, Hickson JA, Msezane L, Rinker-Schaeffer CW, Chen CT.

Mol Imaging. 2013 Jan-Feb;12(1):28-38.

PMID:
23348789
5.

Using MKK4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization.

Krishnan V, Stadick N, Clark R, Bainer R, Veneris JT, Khan S, Drew A, Rinker-Schaeffer C.

Cancer Metastasis Rev. 2012 Dec;31(3-4):605-13. doi: 10.1007/s10555-012-9371-y. Review.

PMID:
22706843
6.

Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.

Bainer RO, Veneris JT, Yamada SD, Montag A, Lingen MW, Gilad Y, Rinker-Schaeffer CW.

Clin Exp Metastasis. 2012 Jun;29(5):397-408. doi: 10.1007/s10585-011-9448-y. Epub 2012 Feb 21.

7.

Building on the foundation of daring hypotheses: using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization.

Knopeke MT, Ritschdorff ET, Clark R, Vander Griend DJ, Khan S, Thobe M, Shear JB, Rinker-Schaeffer CW.

FEBS Lett. 2011 Oct 20;585(20):3159-65. doi: 10.1016/j.febslet.2011.09.007. Epub 2011 Sep 12.

8.

From prostate to bone: key players in prostate cancer bone metastasis.

Thobe MN, Clark RJ, Bainer RO, Prasad SM, Rinker-Schaeffer CW.

Cancers (Basel). 2011;3(1):478-93. doi: 10.3390/cancers3010478.

9.

Metastasis-suppressor genes in clinical practice: lost in translation?

Shoushtari AN, Szmulewitz RZ, Rinker-Schaeffer CW.

Nat Rev Clin Oncol. 2011 Jun;8(6):333-42. doi: 10.1038/nrclinonc.2011.65. Epub 2011 Apr 26. Review.

PMID:
21522123
10.

MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression.

Szmulewitz RZ, Clark R, Lotan T, Otto K, Taylor Veneris J, Macleod K, Rinker-Schaeffer C.

Int J Cancer. 2012 Feb 1;130(3):509-20. doi: 10.1002/ijc.26005. Epub 2011 Apr 25.

11.

Thinking outside the box: using metastasis suppressors as molecular tools.

Thiolloy S, Rinker-Schaeffer CW.

Semin Cancer Biol. 2011 Apr;21(2):89-98. doi: 10.1016/j.semcancer.2010.12.008. Epub 2010 Dec 13. Review.

PMID:
21147228
12.

Disrupting ovarian cancer metastatic colonization: insights from metastasis suppressor studies.

Khan S, Taylor JL, Rinker-Schaeffer CW.

J Oncol. 2010;2010:286925. doi: 10.1155/2010/286925. Epub 2010 Mar 14.

13.

In vitro metastatic colonization of human ovarian cancer cells to the omentum.

Khan SM, Funk HM, Thiolloy S, Lotan TL, Hickson J, Prins GS, Drew AF, Rinker-Schaeffer CW.

Clin Exp Metastasis. 2010 Mar;27(3):185-96. doi: 10.1007/s10585-010-9317-0. Epub 2010 Mar 14.

PMID:
20229256
14.

Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.

Marasa BS, Srikantan S, Masuda K, Abdelmohsen K, Kuwano Y, Yang X, Martindale JL, Rinker-Schaeffer CW, Gorospe M.

Sci Signal. 2009 Oct 27;2(94):ra69. doi: 10.1126/scisignal.2000442.

15.

FYN is overexpressed in human prostate cancer.

Posadas EM, Al-Ahmadie H, Robinson VL, Jagadeeswaran R, Otto K, Kasza KE, Tretiakov M, Siddiqui J, Pienta KJ, Stadler WM, Rinker-Schaeffer C, Salgia R.

BJU Int. 2009 Jan;103(2):171-7. doi: 10.1111/j.1464-410X.2008.08009.x. Epub 2008 Oct 16.

16.

New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.

Taylor JL, Szmulewitz RZ, Lotan T, Hickson J, Griend DV, Yamada SD, Macleod K, Rinker-Schaeffer CW.

Cancer Lett. 2008 Dec 8;272(1):12-22. doi: 10.1016/j.canlet.2008.05.012. Epub 2008 Jun 24. Review.

PMID:
18572308
17.

Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis.

Hickson J, Diane Yamada S, Berger J, Alverdy J, O'Keefe J, Bassler B, Rinker-Schaeffer C.

Clin Exp Metastasis. 2009;26(1):67-76. doi: 10.1007/s10585-008-9177-z. Epub 2008 May 31. Review.

PMID:
18516689
18.

c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.

Lotan T, Hickson J, Souris J, Huo D, Taylor J, Li T, Otto K, Yamada SD, Macleod K, Rinker-Schaeffer CW.

Cancer Res. 2008 Apr 1;68(7):2166-75. doi: 10.1158/0008-5472.CAN-07-1568.

19.

Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.

Robinson VL, Shalhav O, Otto K, Kawai T, Gorospe M, Rinker-Schaeffer CW.

Mol Cancer Res. 2008 Mar;6(3):501-8. doi: 10.1158/1541-7786.MCR-07-2075.

20.

Using metastasis suppressor proteins to dissect interactions among cancer cells and their microenvironment.

Taylor J, Hickson J, Lotan T, Yamada DS, Rinker-Schaeffer C.

Cancer Metastasis Rev. 2008 Mar;27(1):67-73. Review.

PMID:
18049862
21.

Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia.

Lotan TL, Lyon M, Huo D, Taxy JB, Brendler C, Foster BA, Stadler W, Rinker-Schaeffer CW.

J Pathol. 2007 Aug;212(4):386-94.

PMID:
17577251
22.

Stopping cancer before it colonizes.

Rinker-Schaeffer CW, Hickson JA.

Nat Med. 2006 Aug;12(8):887-8. No abstract available.

PMID:
16892031
23.

Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application.

Rinker-Schaeffer CW, O'Keefe JP, Welch DR, Theodorescu D.

Clin Cancer Res. 2006 Jul 1;12(13):3882-9. Review. No abstract available.

24.

The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.

Hickson JA, Huo D, Vander Griend DJ, Lin A, Rinker-Schaeffer CW, Yamada SD.

Cancer Res. 2006 Feb 15;66(4):2264-70.

25.

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7.

Vander Griend DJ, Kocherginsky M, Hickson JA, Stadler WM, Lin A, Rinker-Schaeffer CW.

Cancer Res. 2005 Dec 1;65(23):10984-91.

26.

An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis.

Luu HH, Kang Q, Park JK, Si W, Luo Q, Jiang W, Yin H, Montag AG, Simon MA, Peabody TD, Haydon RC, Rinker-Schaeffer CW, He TC.

Clin Exp Metastasis. 2005;22(4):319-29.

PMID:
16170668
27.

Metastasis suppressor genes: from gene identification to protein function and regulation.

Berger JC, Vander Griend DJ, Robinson VL, Hickson JA, Rinker-Schaeffer CW.

Cancer Biol Ther. 2005 Aug;4(8):805-12. Review.

PMID:
16082183
28.

Adjunctive therapy for men with high risk localized and locally advanced prostate cancer: targeting disseminated tumor cells.

Sokoloff MH, Rinker-Schaeffer CW, Chung LW, Brendler CB.

J Urol. 2004 Dec;172(6 Pt 2):2539-44. Review.

PMID:
15538203
29.

Metastasis suppressor genes: signal transduction, cross-talk and the potential for modulating the behavior of metastatic cells.

Berger JC, Vander Griend D, Stadler WM, Rinker-Schaeffer C.

Anticancer Drugs. 2004 Jul;15(6):559-68. Review.

PMID:
15205597
30.

The basic biology of metastasis.

Robinson VL, Kauffman EC, Sokoloff MH, Rinker-Schaeffer CW.

Cancer Treat Res. 2004;118:1-21. Review. No abstract available.

PMID:
15043186
31.

Suppression of metastasis--a new function for known proteins.

Vander Griend DJ, Berger JC, Rinker-Schaeffer CW.

J Natl Cancer Inst. 2004 Mar 3;96(5):344-5. No abstract available.

PMID:
14996848
32.

A new look at an old problem: the survival and organ-specific growth of metastases.

Vander Griend DJ, Rinker-Schaeffer CW.

Sci STKE. 2004 Jan 13;2004(216):pe3. Review.

PMID:
14734785
33.

Inhibition of prostate cancer metastatic colonization by approximately 4.2 Mb of human chromosome 12.

Jaeger EB, Chekmareva MA, Tennant TR, Luu HH, Hickson JA, Chen SL, Samant RS, Sokoloff MH, Rinker-Schaeffer CW.

Int J Cancer. 2004 Jan 1;108(1):15-22.

34.

MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research.

Robinson VL, Hickson JA, Vander Griend DJ, Dubauskas Z, Rinker-Schaeffer CW.

Clin Exp Metastasis. 2003;20(1):25-30. Review.

PMID:
12650604
35.

Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site.

Kauffman EC, Robinson VL, Stadler WM, Sokoloff MH, Rinker-Schaeffer CW.

J Urol. 2003 Mar;169(3):1122-33. Review.

PMID:
12576866
36.

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

Yamada SD, Hickson JA, Hrobowski Y, Vander Griend DJ, Benson D, Montag A, Karrison T, Huo D, Rutgers J, Adams S, Rinker-Schaeffer CW.

Cancer Res. 2002 Nov 15;62(22):6717-23.

37.

Highlights of the Society of Urologic Oncology meeting, June 2, 2001.

Steinberg GD, Rinker-Schaeffer CW, Sokoloff MH, Brendler CB.

J Urol. 2002 Aug;168(2):653-9. No abstract available.

PMID:
12131337
38.

Metastasis suppression in prostate cancer.

Jaeger EB, Samant RS, Rinker-Schaeffer CW.

Cancer Metastasis Rev. 2001;20(3-4):279-86. Review.

PMID:
12085966
39.

Functional and anatomic imaging of tumor vasculature: high-resolution MR spectroscopic imaging combined with a superparamagnetic contrast agent.

Karczmar GS, Fan X, Al-Hallaq H, River JN, Tarlo K, Kellar KE, Zamora M, Rinker-Schaeffer C, Lipton MJ.

Acad Radiol. 2002 May;9 Suppl 1:S115-8. No abstract available.

PMID:
12019844
40.

Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI.

Fan X, River JN, Zamora M, Tarlo K, Kellar K, Rinker-Schaeffer C, Karczmar GS.

Magn Reson Med. 2001 Jun;45(6):1046-55.

41.

Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.

Kim HL, Vander Griend DJ, Yang X, Benson DA, Dubauskas Z, Yoshida BA, Chekmareva MA, Ichikawa Y, Sokoloff MH, Zhan P, Karrison T, Lin A, Stadler WM, Ichikawa T, Rubin MA, Rinker-Schaeffer CW.

Cancer Res. 2001 Apr 1;61(7):2833-7.

42.

Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis.

Welch DR, Steeg PS, Rinker-Schaeffer CW.

Breast Cancer Res. 2000;2(6):408-16. Epub 2000 Jul 21. Review.

43.

Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer.

Ichikawa T, Hosoki S, Suzuki H, Akakura K, Igarashi T, Furuya Y, Oshimura M, Rinker-Schaeffer CW, Nihei N, Barrett JC, Isaacs JT, Ito H.

Asian J Androl. 2000 Sep;2(3):167-71.

44.

Northern and southern blotting and the polymerase chain reaction to detect gene expression.

Tennant T, Chekmareva M, Rinker-Schaeffer CW.

Methods Mol Med. 2001;57:255-70. doi: 10.1385/1-59259-136-1:255.

PMID:
21340903
45.

Angiogenesis inhibitors.

Tennant TR, Rinker-Schaeffer CW, Stadler WM.

Curr Oncol Rep. 2000 Jan;2(1):11-6. Review.

PMID:
11122819
46.

Metastasis-suppressor genes: a review and perspective on an emerging field.

Yoshida BA, Sokoloff MM, Welch DR, Rinker-Schaeffer CW.

J Natl Cancer Inst. 2000 Nov 1;92(21):1717-30. Review.

PMID:
11058615
47.

Defining the biologic role of genes that regulate prostate cancer metastasis.

Rinker-Schaeffer CW, Welch DR, Sokoloff M.

Curr Opin Urol. 2000 Sep;10(5):397-401. Review.

PMID:
11005442
48.

Development of markers of prostate cancer metastasis. Review and perspective.

Christiano AP, Yoshida BA, Dubauskas Z, Sokoloff M, Rinker-Schaeffer CW.

Urol Oncol. 2000 Sep 1;5(5):217-223. No abstract available.

PMID:
10973711
49.

A G2/M growth arrest response to low-dose intermittent H2O2 in normal uroepithelial cells.

Chien M, Rinker-Schaeffer C, Stadler WM.

Int J Oncol. 2000 Sep;17(3):425-32.

PMID:
10938379
50.

The Dunning model.

Tennant TR, Kim H, Sokoloff M, Rinker-Schaeffer CW.

Prostate. 2000 Jun 1;43(4):295-302. Review. No abstract available.

PMID:
10861749

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