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Items: 1 to 50 of 55

1.

Biochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab.

Agez M, Mandon ED, Iwema T, Gianotti R, Limani F, Herter S, Mössner E, Kusznir EA, Huber S, Lauer M, Ringler P, Ferrara C, Klein C, Jawhari A.

Sci Rep. 2019 Sep 23;9(1):13675. doi: 10.1038/s41598-019-50031-4.

2.

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.

Sustmann C, Dickopf S, Regula JT, Kettenberger H, Mølhøj M, Gassner C, Weininger D, Fenn S, Manigold T, Kling L, Künkele KP, Schwaiger M, Bossenmaier B, Griese JJ, Hopfner KP, Graff-Meyer A, Stahlberg H, Ringler P, Lauer ME, Brinkmann U, Schaefer W, Klein C.

MAbs. 2019 Sep 17:1-13. doi: 10.1080/19420862.2019.1661736. [Epub ahead of print]

PMID:
31526159
3.

Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies.

Hoffmann E, Jordan G, Lauer M, Ringler P, Kusznir EA, Rufer AC, Huber S, Jochner A, Winter G, Staack RF.

Pharm Res. 2019 Jun 28;36(9):129. doi: 10.1007/s11095-019-2661-0.

4.

Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.

Claus C, Ferrara C, Xu W, Sam J, Lang S, Uhlenbrock F, Albrecht R, Herter S, Schlenker R, Hüsser T, Diggelmann S, Challier J, Mössner E, Hosse RJ, Hofer T, Brünker P, Joseph C, Benz J, Ringler P, Stahlberg H, Lauer M, Perro M, Chen S, Küttel C, Bhavani Mohan PL, Nicolini V, Birk MC, Ongaro A, Prince C, Gianotti R, Dugan G, Whitlow CT, Solingapuram Sai KK, Caudell DL, Burgos-Rodriguez AG, Cline JM, Hettich M, Ceppi M, Giusti AM, Crameri F, Driessen W, Morcos PN, Freimoser-Grundschober A, Levitsky V, Amann M, Grau-Richards S, von Hirschheydt T, Tournaviti S, Mølhøj M, Fauti T, Heinzelmann-Schwarz V, Teichgräber V, Colombetti S, Bacac M, Zippelius A, Klein C, Umaña P.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaav5989. doi: 10.1126/scitranslmed.aav5989.

PMID:
31189721
5.

Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing.

Dickopf S, Lauer ME, Ringler P, Spick C, Kern P, Brinkmann U.

Biol Chem. 2019 Jan 9. pii: /j/bchm.ahead-of-print/hsz-2018-0338/hsz-2018-0338.xml. doi: 10.1515/hsz-2018-0338. [Epub ahead of print]

PMID:
30864397
6.

Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing.

Dickopf S, Lauer ME, Ringler P, Spick C, Kern P, Brinkmann U.

Biol Chem. 2019 Feb 25;400(3):343-350. doi: 10.1515/hsz-2018-0338.

PMID:
30763031
7.

Cryo-EM structure of alpha-synuclein fibrils.

Guerrero-Ferreira R, Taylor NM, Mona D, Ringler P, Lauer ME, Riek R, Britschgi M, Stahlberg H.

Elife. 2018 Jul 3;7. pii: e36402. doi: 10.7554/eLife.36402.

8.

Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene.

Seuring C, Ayyer K, Filippaki E, Barthelmess M, Longchamp JN, Ringler P, Pardini T, Wojtas DH, Coleman MA, Dörner K, Fuglerud S, Hammarin G, Habenstein B, Langkilde AE, Loquet A, Meents A, Riek R, Stahlberg H, Boutet S, Hunter MS, Koglin J, Liang M, Ginn HM, Millane RP, Frank M, Barty A, Chapman HN.

Nat Commun. 2018 May 9;9(1):1836. doi: 10.1038/s41467-018-04116-9.

9.

Amyloid Fibril Polymorphism: Almost Identical on the Atomic Level, Mesoscopically Very Different.

Seuring C, Verasdonck J, Ringler P, Cadalbert R, Stahlberg H, Böckmann A, Meier BH, Riek R.

J Phys Chem B. 2017 Mar 2;121(8):1783-1792. doi: 10.1021/acs.jpcb.6b10624. Epub 2017 Feb 20.

PMID:
28075583
10.

Robust image alignment for cryogenic transmission electron microscopy.

McLeod RA, Kowal J, Ringler P, Stahlberg H.

J Struct Biol. 2017 Mar;197(3):279-293. doi: 10.1016/j.jsb.2016.12.006. Epub 2016 Dec 27.

PMID:
28038834
11.

Contributions of the lower dimer to supramolecular actin patterning revealed by TIRF microscopy.

Silván U, Hyotyla J, Mannherz HG, Ringler P, Müller SA, Aebi U, Maier T, Schoenenberger CA.

J Struct Biol. 2016 Aug;195(2):159-166. doi: 10.1016/j.jsb.2016.05.008. Epub 2016 May 14.

PMID:
27189866
12.

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V.

MAbs. 2016 Jul;8(5):928-40. doi: 10.1080/19420862.2016.1168960. Epub 2016 Mar 31.

13.

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.

Lauer ME, Graff-Meyer A, Rufer AC, Maugeais C, von der Mark E, Matile H, D'Arcy B, Magg C, Ringler P, Müller SA, Scherer S, Dernick G, Thoma R, Hennig M, Niesor EJ, Stahlberg H.

J Struct Biol. 2016 May;194(2):191-8. doi: 10.1016/j.jsb.2016.02.016. Epub 2016 Feb 12.

14.

Principles Governing the Self-Assembly of Coiled-Coil Protein Nanoparticles.

Indelicato G, Wahome N, Ringler P, Müller SA, Nieh MP, Burkhard P, Twarock R.

Biophys J. 2016 Feb 2;110(3):646-660. doi: 10.1016/j.bpj.2015.10.057.

15.

Very high-density lipoprotein and vitellin as carriers of novel biliverdins IXα with a farnesyl side-chain presumably derived from heme A in Spodoptera littoralis.

Kayser H, Nimtz M, Ringler P, Müller SA.

Insect Biochem Mol Biol. 2016 Jan;68:41-51. doi: 10.1016/j.ibmb.2015.10.017. Epub 2015 Nov 4.

PMID:
26546815
16.

Tiling Assembly: a new tool for reference annotation-independent transcript assembly and novel gene identification by RNA-sequencing.

Watanabe KA, Homayouni A, Tufano T, Lopez J, Ringler P, Rushton P, Shen QJ.

DNA Res. 2015 Oct;22(5):319-29. doi: 10.1093/dnares/dsv015. Epub 2015 Sep 3.

17.

Optimizing the design of protein nanoparticles as carriers for vaccine applications.

Doll TA, Neef T, Duong N, Lanar DE, Ringler P, Müller SA, Burkhard P.

Nanomedicine. 2015 Oct;11(7):1705-13. doi: 10.1016/j.nano.2015.05.003. Epub 2015 Jun 4.

18.

Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.

Zhang L, Gu L, Ringler P, Smith S, Rushton PJ, Shen QJ.

Plant Sci. 2015 Jul;236:214-22. doi: 10.1016/j.plantsci.2015.04.014. Epub 2015 Apr 24.

PMID:
26025535
19.

Structural and mechanistic paradigm of leptin receptor activation revealed by complexes with wild-type and antagonist leptins.

Moharana K, Zabeau L, Peelman F, Ringler P, Stahlberg H, Tavernier J, Savvides SN.

Structure. 2014 Jun 10;22(6):866-77. doi: 10.1016/j.str.2014.04.012. Epub 2014 May 29.

20.

2dx_automator: implementation of a semiautomatic high-throughput high-resolution cryo-electron crystallography pipeline.

Scherer S, Kowal J, Chami M, Dandey V, Arheit M, Ringler P, Stahlberg H.

J Struct Biol. 2014 May;186(2):302-7. doi: 10.1016/j.jsb.2014.03.016. Epub 2014 Mar 28.

21.

openBEB: open biological experiment browser for correlative measurements.

Ramakrishnan C, Bieri A, Sauter N, Roizard S, Ringler P, Müller SA, Goldie KN, Enimanev K, Stahlberg H, Rinn B, Braun T.

BMC Bioinformatics. 2014 Mar 26;15:84. doi: 10.1186/1471-2105-15-84.

22.

Cryo-electron microscopy of membrane proteins.

Goldie KN, Abeyrathne P, Kebbel F, Chami M, Ringler P, Stahlberg H.

Methods Mol Biol. 2014;1117:325-41. doi: 10.1007/978-1-62703-776-1_15.

23.

Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core.

Kowal J, Chami M, Ringler P, Müller SA, Kudryashev M, Castaño-Díez D, Amstutz M, Cornelis GR, Stahlberg H, Engel A.

Structure. 2013 Dec 3;21(12):2152-61. doi: 10.1016/j.str.2013.09.012. Epub 2013 Oct 24.

24.

RNA-sequencing reveals previously unannotated protein- and microRNA-coding genes expressed in aleurone cells of rice seeds.

Watanabe KA, Ringler P, Gu L, Shen QJ.

Genomics. 2014 Jan;103(1):122-34. doi: 10.1016/j.ygeno.2013.10.007. Epub 2013 Nov 4.

25.

The rhodopsin-transducin complex houses two distinct rhodopsin molecules.

Jastrzebska B, Ringler P, Palczewski K, Engel A.

J Struct Biol. 2013 May;182(2):164-72. doi: 10.1016/j.jsb.2013.02.014. Epub 2013 Feb 28.

26.

Optimizing the refolding conditions of self-assembling polypeptide nanoparticles that serve as repetitive antigen display systems.

Yang Y, Ringler P, Müller SA, Burkhard P.

J Struct Biol. 2012 Jan;177(1):168-76. doi: 10.1016/j.jsb.2011.11.011. Epub 2011 Nov 17.

PMID:
22115997
27.

Connecting μ-fluidics to electron microscopy.

Kemmerling S, Ziegler J, Schweighauser G, Arnold SA, Giss D, Müller SA, Ringler P, Goldie KN, Goedecke N, Hierlemann A, Stahlberg H, Engel A, Braun T.

J Struct Biol. 2012 Jan;177(1):128-34. doi: 10.1016/j.jsb.2011.11.001. Epub 2011 Nov 9.

PMID:
22094535
28.

Rhodopsin-transducin heteropentamer: three-dimensional structure and biochemical characterization.

Jastrzebska B, Ringler P, Lodowski DT, Moiseenkova-Bell V, Golczak M, Müller SA, Palczewski K, Engel A.

J Struct Biol. 2011 Dec;176(3):387-94. doi: 10.1016/j.jsb.2011.08.016. Epub 2011 Sep 6.

29.

WRKY transcription factors: key components in abscisic acid signalling.

Rushton DL, Tripathi P, Rabara RC, Lin J, Ringler P, Boken AK, Langum TJ, Smidt L, Boomsma DD, Emme NJ, Chen X, Finer JJ, Shen QJ, Rushton PJ.

Plant Biotechnol J. 2012 Jan;10(1):2-11. doi: 10.1111/j.1467-7652.2011.00634.x. Epub 2011 Jun 22. Review.

30.

Direct control of the spatial arrangement of gold nanoparticles in organic-inorganic hybrid superstructures.

Hermes JP, Sander F, Peterle T, Cioffi C, Ringler P, Pfohl T, Mayor M.

Small. 2011 Apr 4;7(7):920-9. doi: 10.1002/smll.201002101. Epub 2011 Mar 11.

31.

Bipartite design of a self-fibrillating protein copolymer with nanopatterned peptide display capabilities.

Bruning M, Kreplak L, Leopoldseder S, Müller SA, Ringler P, Duchesne L, Fernig DG, Engel A, Ucurum-Fotiadis Z, Mayans O.

Nano Lett. 2010 Nov 10;10(11):4533-7. doi: 10.1021/nl1024886. Epub 2010 Oct 18.

PMID:
20954695
32.

WRKY transcription factors.

Rushton PJ, Somssich IE, Ringler P, Shen QJ.

Trends Plant Sci. 2010 May;15(5):247-58. doi: 10.1016/j.tplants.2010.02.006. Epub 2010 Mar 19. Review.

PMID:
20304701
33.

Molecular architecture of Streptococcus pneumoniae TIGR4 pili.

Hilleringmann M, Ringler P, Müller SA, De Angelis G, Rappuoli R, Ferlenghi I, Engel A.

EMBO J. 2009 Dec 16;28(24):3921-30. doi: 10.1038/emboj.2009.360.

34.

Isolation, characterisation and molecular imaging of a high-molecular-weight insect biliprotein, a member of the hexameric arylphorin protein family.

Kayser H, Mann K, Machaidze G, Nimtz M, Ringler P, Müller SA, Aebi U.

J Mol Biol. 2009 May 29;389(1):74-89. doi: 10.1016/j.jmb.2009.03.075. Epub 2009 Apr 8.

PMID:
19361516
35.

Omp85(Tt) from Thermus thermophilus HB27: an ancestral type of the Omp85 protein family.

Nesper J, Brosig A, Ringler P, Patel GJ, Müller SA, Kleinschmidt JH, Boos W, Diederichs K, Welte W.

J Bacteriol. 2008 Jul;190(13):4568-75. doi: 10.1128/JB.00369-08. Epub 2008 May 2.

36.

Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding.

Riek U, Scholz R, Konarev P, Rufer A, Suter M, Nazabal A, Ringler P, Chami M, Müller SA, Neumann D, Forstner M, Hennig M, Zenobi R, Engel A, Svergun D, Schlattner U, Wallimann T.

J Biol Chem. 2008 Jun 27;283(26):18331-43. doi: 10.1074/jbc.M708379200. Epub 2008 Mar 27.

37.

Molecular anatomy of a trafficking organelle.

Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmüller H, Heuser J, Wieland F, Jahn R.

Cell. 2006 Nov 17;127(4):831-46.

38.

Impact of disease mutations on the desmin filament assembly process.

Bär H, Mücke N, Ringler P, Müller SA, Kreplak L, Katus HA, Aebi U, Herrmann H.

J Mol Biol. 2006 Jul 28;360(5):1031-42. Epub 2006 Jun 16.

PMID:
16828798
39.

Immunogenicity and structural characterisation of an in vitro folded meningococcal siderophore receptor (FrpB, FetA).

Kortekaas J, Müller SA, Ringler P, Gregorini M, Weynants VE, Rutten L, Bos MP, Tommassen J.

Microbes Infect. 2006 Jul;8(8):2145-53. Epub 2006 May 24.

PMID:
16797200
40.

Cytotoxin ClyA from Escherichia coli assembles to a 13-meric pore independent of its redox-state.

Eifler N, Vetsch M, Gregorini M, Ringler P, Chami M, Philippsen A, Fritz A, Müller SA, Glockshuber R, Engel A, Grauschopf U.

EMBO J. 2006 Jun 7;25(11):2652-61. Epub 2006 May 11.

41.

The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles.

Mueller CA, Broz P, Müller SA, Ringler P, Erne-Brand F, Sorg I, Kuhn M, Engel A, Cornelis GR.

Science. 2005 Oct 28;310(5748):674-6.

42.

Molecular architecture and assembly mechanism of Drosophila tripeptidyl peptidase II.

Rockel B, Peters J, Müller SA, Seyit G, Ringler P, Hegerl R, Glaeser RM, Baumeister W.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10135-40. Epub 2005 Jul 8.

43.

Structure and assembly of the pseudopilin PulG.

Köhler R, Schäfer K, Müller S, Vignon G, Diederichs K, Philippsen A, Ringler P, Pugsley AP, Engel A, Welte W.

Mol Microbiol. 2004 Nov;54(3):647-64.

44.

Structure and electrophysiological properties of the YscC secretin from the type III secretion system of Yersinia enterocolitica.

Burghout P, van Boxtel R, Van Gelder P, Ringler P, Müller SA, Tommassen J, Koster M.

J Bacteriol. 2004 Jul;186(14):4645-54.

45.

Self-assembly of proteins into designed networks.

Ringler P, Schulz GE.

Science. 2003 Oct 3;302(5642):106-9.

46.

Imaging streptavidin 2D crystals on biotinylated lipid monolayers at high resolution with the atomic force microscope.

Scheuring S, Muller DJ, Ringler P, Heymann JB, Engel A.

J Microsc. 1999 Jan;193(1):28-35.

47.

OmpA membrane domain as a tight-binding anchor for lipid bilayers.

Ringler P, Schulz GE.

Chembiochem. 2002 May 3;3(5):463-6. No abstract available.

PMID:
12007182
48.

The aquaporin sidedness revisited.

Scheuring S, Tittmann P, Stahlberg H, Ringler P, Borgnia M, Agre P, Gross H, Engel A.

J Mol Biol. 2000 Jun 23;299(5):1271-8.

PMID:
10873451
49.

Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography.

Ringler P, Borgnia MJ, Stahlberg H, Maloney PC, Agre P, Engel A.

J Mol Biol. 1999 Sep 3;291(5):1181-90.

PMID:
10518953
50.

High resolution AFM topographs of the Escherichia coli water channel aquaporin Z.

Scheuring S, Ringler P, Borgnia M, Stahlberg H, Müller DJ, Agre P, Engel A.

EMBO J. 1999 Sep 15;18(18):4981-7.

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