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Items: 6


FDA Approval: Alectinib for the Treatment of Metastatic, ALK-Positive Non-Small Cell Lung Cancer Following Crizotinib.

Larkins E, Blumenthal GM, Chen H, He K, Agarwal R, Gieser G, Stephens O, Zahalka E, Ringgold K, Helms W, Shord S, Yu J, Zhao H, Davis G, McKee AE, Keegan P, Pazdur R.

Clin Cancer Res. 2016 Nov 1;22(21):5171-5176. Epub 2016 Jul 13.


Hypocretinergic and cholinergic contributions to sleep-wake disturbances in a mouse model of traumatic brain injury.

Thomasy HE, Febinger HY, Ringgold KM, Gemma C, Opp MR.

Neurobiol Sleep Circadian Rhythms. 2016 Apr 19;2:71-84. doi: 10.1016/j.nbscr.2016.03.001. eCollection 2017 Jan.


Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury.

Febinger HY, Thomasy HE, Pavlova MN, Ringgold KM, Barf PR, George AM, Grillo JN, Bachstetter AD, Garcia JA, Cardona AE, Opp MR, Gemma C.

J Neuroinflammation. 2015 Sep 2;12:154. doi: 10.1186/s12974-015-0386-5.


Sleep fragmentation and sepsis differentially impact blood-brain barrier integrity and transport of tumor necrosis factor-α in aging.

Opp MR, George A, Ringgold KM, Hansen KM, Bullock KM, Banks WA.

Brain Behav Immun. 2015 Nov;50:259-265. doi: 10.1016/j.bbi.2015.07.023. Epub 2015 Jul 26.


Prolonged sleep fragmentation of mice exacerbates febrile responses to lipopolysaccharide.

Ringgold KM, Barf RP, George A, Sutton BC, Opp MR.

J Neurosci Methods. 2013 Sep 30;219(1):104-12. doi: 10.1016/j.jneumeth.2013.07.008. Epub 2013 Jul 16.


First FDA approval of dual anti-HER2 regimen: pertuzumab in combination with trastuzumab and docetaxel for HER2-positive metastatic breast cancer.

Blumenthal GM, Scher NS, Cortazar P, Chattopadhyay S, Tang S, Song P, Liu Q, Ringgold K, Pilaro AM, Tilley A, King KE, Graham L, Rellahan BL, Weinberg WC, Chi B, Thomas C, Hughes P, Ibrahim A, Justice R, Pazdur R.

Clin Cancer Res. 2013 Sep 15;19(18):4911-6. doi: 10.1158/1078-0432.CCR-13-1212. Epub 2013 Jun 25.

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