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Items: 31

1.

Contribution of pilus type 2b to invasive disease caused by a Streptococcus agalactiae ST-17 strain.

Lazzarin M, Mu R, Fabbrini M, Ghezzo C, Rinaudo CD, Doran KS, Margarit I.

BMC Microbiol. 2017 Jul 3;17(1):148. doi: 10.1186/s12866-017-1057-8.

2.

Immune Responses to Invasive Group B Streptococcal Disease in Adults.

Edwards MS, Rench MA, Rinaudo CD, Fabbrini M, Tuscano G, Buffi G, Bartolini E, Bonacci S, Baker CJ, Margarit I.

Emerg Infect Dis. 2016 Nov;22(11):1877-1883. doi: 10.3201/eid2211.160914.

3.

Genomic Analysis Reveals Multi-Drug Resistance Clusters in Group B Streptococcus CC17 Hypervirulent Isolates Causing Neonatal Invasive Disease in Southern Mainland China.

Campisi E, Rosini R, Ji W, Guidotti S, Rojas-López M, Geng G, Deng Q, Zhong H, Wang W, Liu H, Nan C, Margarit I, Rinaudo CD.

Front Microbiol. 2016 Aug 15;7:1265. doi: 10.3389/fmicb.2016.01265. eCollection 2016.

4.

Serotype IV Streptococcus agalactiae ST-452 has arisen from large genomic recombination events between CC23 and the hypervirulent CC17 lineages.

Campisi E, Rinaudo CD, Donati C, Barucco M, Torricelli G, Edwards MS, Baker CJ, Margarit I, Rosini R.

Sci Rep. 2016 Jul 14;6:29799. doi: 10.1038/srep29799.

5.

The Protective Value of Maternal Group B Streptococcus Antibodies: Quantitative and Functional Analysis of Naturally Acquired Responses to Capsular Polysaccharides and Pilus Proteins in European Maternal Sera.

Fabbrini M, Rigat F, Rinaudo CD, Passalaqua I, Khacheh S, Creti R, Baldassarri L, Carboni F, Anderloni G, Rosini R, Maione D, Grandi G, Telford JL, Margarit I.

Clin Infect Dis. 2016 Sep 15;63(6):746-753. doi: 10.1093/cid/ciw377. Epub 2016 Jul 11.

PMID:
27402816
6.

Estimating the burden of invasive Group B Streptococcal disease in young infants in southern mainland China: an observational study.

Liu H, Zeng H, Wang W, Deng Q, Margarit I, Rinaudo CD, Swarthout T, Cunnington M, Ji W, Geng G.

Int J Clin Exp Med. 2015 Aug 15;8(8):13699-707. eCollection 2015.

7.

Group B Streptococcus vaccine: state of the art.

Nuccitelli A, Rinaudo CD, Maione D.

Ther Adv Vaccines. 2015 May;3(3):76-90. doi: 10.1177/2051013615579869. Review.

8.

Noncanonical sortase-mediated assembly of pilus type 2b in group B Streptococcus.

Lazzarin M, Cozzi R, Malito E, Martinelli M, D'Onofrio M, Maione D, Margarit I, Rinaudo CD.

FASEB J. 2015 Nov;29(11):4629-40. doi: 10.1096/fj.15-272500. Epub 2015 Jul 22.

PMID:
26202865
9.

Structure and assembly of group B streptococcus pilus 2b backbone protein.

Cozzi R, Malito E, Lazzarin M, Nuccitelli A, Castagnetti A, Bottomley MJ, Margarit I, Maione D, Rinaudo CD.

PLoS One. 2015 May 5;10(5):e0125875. doi: 10.1371/journal.pone.0125875. eCollection 2015.

10.

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.

Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3680-5. doi: 10.1073/pnas.1424924112. Epub 2015 Mar 9.

11.

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.

Schluepen C, Malito E, Marongiu A, Schirle M, McWhinnie E, Lo Surdo P, Biancucci M, Falugi F, Nardi-Dei V, Marchi S, Fontana MR, Lombardi B, De Falco MG, Rinaudo CD, Spraggon G, Nissum M, Bagnoli F, Grandi G, Bottomley MJ, Liberatori S.

Biochem J. 2013 Nov 1;455(3):273-84. doi: 10.1042/BJ20130540.

PMID:
23895222
12.

Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus.

Nuccitelli A, Rinaudo CD, Brogioni B, Cozzi R, Ferrer-Navarro M, Yero D, Telford JL, Grandi G, Daura X, Zacharias M, Maione D.

PLoS Comput Biol. 2013;9(6):e1003115. doi: 10.1371/journal.pcbi.1003115. Epub 2013 Jun 27.

13.

Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.

Cozzi R, Zerbini F, Assfalg M, D'Onofrio M, Biagini M, Martinelli M, Nuccitelli A, Norais N, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2013 Aug;27(8):3144-54. doi: 10.1096/fj.13-227793. Epub 2013 Apr 30.

PMID:
23631841
14.

Capsular gene typing of Streptococcus agalactiae compared to serotyping by latex agglutination.

Yao K, Poulsen K, Maione D, Rinaudo CD, Baldassarri L, Telford JL, Sørensen UB; Members of the DEVANI Study Group, Kilian M.

J Clin Microbiol. 2013 Feb;51(2):503-7. doi: 10.1128/JCM.02417-12. Epub 2012 Nov 28.

15.

Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.

Cozzi R, Prigozhin D, Rosini R, Abate F, Bottomley MJ, Grandi G, Telford JL, Rinaudo CD, Maione D, Alber T.

PLoS One. 2012;7(11):e49048. doi: 10.1371/journal.pone.0049048. Epub 2012 Nov 8.

16.

New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly.

Cozzi R, Nuccitelli A, D'Onofrio M, Necchi F, Rosini R, Zerbini F, Biagini M, Norais N, Beier C, Telford JL, Grandi G, Assfalg M, Zacharias M, Maione D, Rinaudo CD.

FASEB J. 2012 May;26(5):2008-18. doi: 10.1096/fj.11-196378. Epub 2012 Jan 17.

PMID:
22253480
17.

Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.

Necchi F, Nardi-Dei V, Biagini M, Assfalg M, Nuccitelli A, Cozzi R, Norais N, Telford JL, Rinaudo CD, Grandi G, Maione D.

PLoS One. 2011;6(10):e25300. doi: 10.1371/journal.pone.0025300. Epub 2011 Oct 4.

18.

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.

Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18.

19.

Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.

Cozzi R, Malito E, Nuccitelli A, D'Onofrio M, Martinelli M, Ferlenghi I, Grandi G, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2011 Jun;25(6):1874-86. doi: 10.1096/fj.10-174797. Epub 2011 Feb 25.

PMID:
21357525
20.

Specific involvement of pilus type 2a in biofilm formation in group B Streptococcus.

Rinaudo CD, Rosini R, Galeotti CL, Berti F, Necchi F, Reguzzi V, Ghezzo C, Telford JL, Grandi G, Maione D.

PLoS One. 2010 Feb 15;5(2):e9216. doi: 10.1371/journal.pone.0009216.

21.

Vaccinology in the genome era.

Rinaudo CD, Telford JL, Rappuoli R, Seib KL.

J Clin Invest. 2009 Sep;119(9):2515-25. doi: 10.1172/JCI38330. Review.

22.

Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1.

Doro F, Liberatori S, Rodríguez-Ortega MJ, Rinaudo CD, Rosini R, Mora M, Scarselli M, Altindis E, D'Aurizio R, Stella M, Margarit I, Maione D, Telford JL, Norais N, Grandi G.

Mol Cell Proteomics. 2009 Jul;8(7):1728-37. doi: 10.1074/mcp.M800486-MCP200. Epub 2009 Apr 28.

23.

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm.

Margarit I, Rinaudo CD, Galeotti CL, Maione D, Ghezzo C, Buttazzoni E, Rosini R, Runci Y, Mora M, Buccato S, Pagani M, Tresoldi E, Berardi A, Creti R, Baker CJ, Telford JL, Grandi G.

J Infect Dis. 2009 Jan 1;199(1):108-15. doi: 10.1086/595564.

PMID:
19086816
24.

Sortase A utilizes an ancillary protein anchor for efficient cell wall anchoring of pili in Streptococcus agalactiae.

Nobbs AH, Rosini R, Rinaudo CD, Maione D, Grandi G, Telford JL.

Infect Immun. 2008 Aug;76(8):3550-60. doi: 10.1128/IAI.01613-07. Epub 2008 Jun 9.

25.

Use of Lactococcus lactis expressing pili from group B Streptococcus as a broad-coverage vaccine against streptococcal disease.

Buccato S, Maione D, Rinaudo CD, Volpini G, Taddei AR, Rosini R, Telford JL, Grandi G, Margarit I.

J Infect Dis. 2006 Aug 1;194(3):331-40. Epub 2006 Jun 30.

PMID:
16826481
26.

Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae.

Rosini R, Rinaudo CD, Soriani M, Lauer P, Mora M, Maione D, Taddei A, Santi I, Ghezzo C, Brettoni C, Buccato S, Margarit I, Grandi G, Telford JL.

Mol Microbiol. 2006 Jul;61(1):126-41.

27.

Identification of a universal Group B streptococcus vaccine by multiple genome screen.

Maione D, Margarit I, Rinaudo CD, Masignani V, Mora M, Scarselli M, Tettelin H, Brettoni C, Iacobini ET, Rosini R, D'Agostino N, Miorin L, Buccato S, Mariani M, Galli G, Nogarotto R, Nardi-Dei V, Vegni F, Fraser C, Mancuso G, Teti G, Madoff LC, Paoletti LC, Rappuoli R, Kasper DL, Telford JL, Grandi G.

Science. 2005 Jul 1;309(5731):148-50. Erratum in: Science. 2013 Jan 11;339(6116):141. Nardi Dei, Vincenzo [corrected to Nardi-Dei, Vincenzo].

28.

Genome analysis reveals pili in Group B Streptococcus.

Lauer P, Rinaudo CD, Soriani M, Margarit I, Maione D, Rosini R, Taddei AR, Mora M, Rappuoli R, Grandi G, Telford JL.

Science. 2005 Jul 1;309(5731):105.

29.

Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates.

Lamartina S, Silvi L, Roscilli G, Casimiro D, Simon AJ, Davies ME, Shiver JW, Rinaudo CD, Zampaglione I, Fattori E, Colloca S, Gonzalez Paz O, Laufer R, Bujard H, Cortese R, Ciliberto G, Toniatti C.

Mol Ther. 2003 Feb;7(2):271-80.

30.

Long-term and tight control of gene expression in mouse skeletal muscle by a new hybrid human transcription factor.

Roscilli G, Rinaudo CD, Cimino M, Sporeno E, Lamartina S, Ciliberto G, Toniatti C.

Mol Ther. 2002 Nov;6(5):653-63.

31.

Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators.

Lamartina S, Roscilli G, Rinaudo CD, Sporeno E, Silvi L, Hillen W, Bujard H, Cortese R, Ciliberto G, Toniatti C.

Hum Gene Ther. 2002 Jan 20;13(2):199-210.

PMID:
11812277

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