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Items: 1 to 50 of 70

1.

Structural and functional investigation of the Small Ribosomal Subunit Biogenesis GTPase A (RsgA) from Pseudomonas aeruginosa.

Rocchio S, Santorelli D, Rinaldo S, Franceschini M, Malatesta F, Imperi F, Federici L, Travaglini-Allocatelli C, Di Matteo A.

FEBS J. 2019 Jun 14. doi: 10.1111/febs.14959. [Epub ahead of print]

PMID:
31199072
2.

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism.

Guiducci G, Paone A, Tramonti A, Giardina G, Rinaldo S, Bouzidi A, Magnifico MC, Marani M, Menendez JA, Fatica A, Macone A, Armaos A, Tartaglia GG, Contestabile R, Paiardini A, Cutruzzolà F.

Nucleic Acids Res. 2019 Feb 27. pii: gkz129. doi: 10.1093/nar/gkz129. [Epub ahead of print]

3.

AbobotulinumtoxinA: A New Therapy for Hip Osteoarthritis. A Prospective Randomized Double-Blind Multicenter Study.

Eleopra R, Rinaldo S, Lettieri C, Santamato A, Bortolotti P, Lentino C, Tamborino C, Causero A, Devigili G.

Toxins (Basel). 2018 Oct 31;10(11). pii: E448. doi: 10.3390/toxins10110448.

4.

Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa.

Mantoni F, Paiardini A, Brunotti P, D'Angelo C, Cervoni L, Paone A, Cappellacci L, Petrelli R, Ricciutelli M, Leoni L, Rampioni G, Arcovito A, Rinaldo S, Cutruzzolà F, Giardina G.

FEBS J. 2018 Oct;285(20):3815-3834. doi: 10.1111/febs.14634. Epub 2018 Sep 7.

PMID:
30106221
5.

A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa.

Paiardini A, Mantoni F, Giardina G, Paone A, Janson G, Leoni L, Rampioni G, Cutruzzolà F, Rinaldo S.

Proteins. 2018 Oct;86(10):1088-1096. doi: 10.1002/prot.25587. Epub 2018 Sep 8.

PMID:
30040157
6.

The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.

Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico MC, Bouzidi A, Pontecorvi V, Guiducci G, Zamparelli C, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F.

FEBS J. 2018 Sep;285(17):3238-3253. doi: 10.1111/febs.14610. Epub 2018 Aug 7.

PMID:
30035852
7.

Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.

Tramonti A, Paiardini A, Paone A, Bouzidi A, Giardina G, Guiducci G, Magnifico MC, Rinaldo S, McDermott L, Menendez JA, Contestabile R, Cutruzzolà F.

Arch Biochem Biophys. 2018 Sep 1;653:71-79. doi: 10.1016/j.abb.2018.07.001. Epub 2018 Jul 4.

PMID:
29991441
8.

The epidemiology of Parkinson's disease in the Italian region Friuli Venezia Giulia: a population-based study with administrative data.

Valent F, Devigili G, Rinaldo S, Del Zotto S, Tullio A, Eleopra R.

Neurol Sci. 2018 Apr;39(4):699-704. doi: 10.1007/s10072-018-3273-x. Epub 2018 Feb 9.

PMID:
29427166
9.

Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms.

Rinaldo S, Giardina G, Mantoni F, Paone A, Cutruzzolà F.

FEMS Microbiol Lett. 2018 Mar 1;365(6). doi: 10.1093/femsle/fny029.

PMID:
29401255
10.

Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases.

Rinaldo S, Giardina G, Mantoni F, Paiardini A, Paone A, Cutruzzolà F.

Methods Mol Biol. 2017;1657:431-453. doi: 10.1007/978-1-4939-7240-1_32.

PMID:
28889312
11.

Chronic pain in Gaucher disease: skeletal or neuropathic origin?

Devigili G, De Filippo M, Ciana G, Dardis A, Lettieri C, Rinaldo S, Macor D, Moro A, Eleopra R, Bembi B.

Orphanet J Rare Dis. 2017 Aug 31;12(1):148. doi: 10.1186/s13023-017-0700-7.

12.

Post-anoxic status epilepticus: which variable could modify prognosis? A single-center experience.

Lettieri C, Devigili G, Pauletto G, Isola M, Rinaldo S, Budai R, Eleopra R.

Minerva Anestesiol. 2017 Dec;83(12):1255-1264. doi: 10.23736/S0375-9393.17.11629-9. Epub 2017 Jul 5.

13.

Weight gain after STN-DBS: The role of reward sensitivity and impulsivity.

Aiello M, Eleopra R, Foroni F, Rinaldo S, Rumiati RI.

Cortex. 2017 Jul;92:150-161. doi: 10.1016/j.cortex.2017.04.005. Epub 2017 Apr 21.

PMID:
28494345
14.

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.

Asteriti IA, Daidone F, Colotti G, Rinaldo S, Lavia P, Guarguaglini G, Paiardini A.

Oncotarget. 2017 May 9;8(19):32117-32133. doi: 10.18632/oncotarget.16738.

15.

Glucose Metabolism in the Progression of Prostate Cancer.

Cutruzzolà F, Giardina G, Marani M, Macone A, Paiardini A, Rinaldo S, Paone A.

Front Physiol. 2017 Feb 21;8:97. doi: 10.3389/fphys.2017.00097. eCollection 2017. Review.

16.

Idiopathic delayed-onset edema surrounding deep brain stimulation leads: Insights from a case series and systematic literature review.

de Cuba CM, Albanese A, Antonini A, Cossu G, Deuschl G, Eleopra R, Galati A, Hoffmann CF, Knudsen K, Landi A, Lanotte MM, Marcante A, Mosch A, Pilleri M, Reich MM, Ricchi V, Rinaldo S, Romito LM, Saba FS, Sacristan HE, Schuurman PR, Trezza A, van den Munckhof P, Volkmann J, Zibetti M, Contarino MF.

Parkinsonism Relat Disord. 2016 Nov;32:108-115. doi: 10.1016/j.parkreldis.2016.09.007. Epub 2016 Sep 6. Review.

17.

Levodopa/carbidopa intestinal gel therapy for advanced Parkinson Disease: AN early toxic effect for small nerve fibers?

Devigili G, Rinaldo S, Lettieri C, Eleopra R.

Muscle Nerve. 2016 Nov;54(5):970-972. doi: 10.1002/mus.25377. Epub 2016 Sep 26.

PMID:
27514937
18.

A relationship between temperature and aggression in NFL football penalties.

Craig C, Overbeek RW, Condon MV, Rinaldo SB.

J Sport Health Sci. 2016 Jun;5(2):205-210. doi: 10.1016/j.jshs.2015.01.001. Epub 2015 Jan 9.

19.

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

Marani M, Paone A, Fiascarelli A, Macone A, Gargano M, Rinaldo S, Giardina G, Pontecorvi V, Koes D, McDermott L, Yang T, Paiardini A, Contestabile R, Cutruzzolà F.

Oncotarget. 2016 Jan 26;7(4):4570-83. doi: 10.18632/oncotarget.6726.

20.

Novel genetic tools to tackle c-di-GMP-dependent signalling in Pseudomonas aeruginosa.

Pawar SV, Messina M, Rinaldo S, Cutruzzolà F, Kaever V, Rampioni G, Leoni L.

J Appl Microbiol. 2016 Jan;120(1):205-17. doi: 10.1111/jam.12984.

21.

Synthesis of Triazole-Linked Analogues of c-di-GMP and Their Interactions with Diguanylate Cyclase.

Fernicola S, Torquati I, Paiardini A, Giardina G, Rampioni G, Messina M, Leoni L, Del Bello F, Petrelli R, Rinaldo S, Cappellacci L, Cutruzzolà F.

J Med Chem. 2015 Oct 22;58(20):8269-84. doi: 10.1021/acs.jmedchem.5b01184. Epub 2015 Oct 12.

PMID:
26426545
22.

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD.

Fernicola S, Paiardini A, Giardina G, Rampioni G, Leoni L, Cutruzzolà F, Rinaldo S.

J Bacteriol. 2015 Sep 28;198(1):147-56. doi: 10.1128/JB.00742-15. Print 2016 Jan 1.

23.

Side and time variability of intraepidermal nerve fiber density.

Lauria G, Dacci P, Lombardi R, Cazzato D, Porretta-Serapiglia C, Taiana M, Sassone J, Dalla Bella E, Rinaldo S, Lettieri C, Eleopra R, Devigili G.

Neurology. 2015 Jun 9;84(23):2368-71. doi: 10.1212/WNL.0000000000001666. Epub 2015 May 13.

24.

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site.

Rinaldo S, Paiardini A, Stelitano V, Brunotti P, Cervoni L, Fernicola S, Protano C, Vitali M, Cutruzzolà F, Giardina G.

J Bacteriol. 2015 Apr;197(8):1525-35. doi: 10.1128/JB.02606-14. Epub 2015 Feb 17.

25.

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

Paiardini A, Fiascarelli A, Rinaldo S, Daidone F, Giardina G, Koes DR, Parroni A, Montini G, Marani M, Paone A, McDermott LA, Contestabile R, Cutruzzolà F.

ChemMedChem. 2015 Mar;10(3):490-7. doi: 10.1002/cmdc.201500028. Epub 2015 Feb 10.

26.

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.

Giardina G, Brunotti P, Fiascarelli A, Cicalini A, Costa MG, Buckle AM, di Salvo ML, Giorgi A, Marani M, Paone A, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F.

FEBS J. 2015 Apr;282(7):1225-41. doi: 10.1111/febs.13211. Epub 2015 Feb 13.

27.

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

Paone A, Marani M, Fiascarelli A, Rinaldo S, Giardina G, Contestabile R, Paiardini A, Cutruzzolà F.

Cell Death Dis. 2014 Nov 20;5:e1525. doi: 10.1038/cddis.2014.482.

28.

Theoretical analysis of electrochemical surface-area loss in supported nanoparticle catalysts.

Rinaldo SG, Urchaga P, Hu J, Lee W, Stumper J, Rice C, Eikerling M.

Phys Chem Chem Phys. 2014 Dec 28;16(48):26876-86. doi: 10.1039/c4cp03349c.

PMID:
25375887
29.

Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis.

Rinaldo S, Giardina G, Cutruzzolà F.

Biochem Biophys Res Commun. 2014 Aug 29;451(3):449-54. doi: 10.1016/j.bbrc.2014.08.020. Epub 2014 Aug 10.

PMID:
25117445
30.

Clinical outcome of deep brain stimulation for dystonia: constant-current or constant-voltage stimulation? A non-randomized study.

Lettieri C, Rinaldo S, Devigili G, Pisa F, Mucchiut M, Belgrado E, Mondani M, D'Auria S, Ius T, Skrap M, Eleopra R.

Eur J Neurol. 2015 Jun;22(6):919-26. doi: 10.1111/ene.12515. Epub 2014 Jul 10.

PMID:
25041419
31.

Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.

Cutruzzolà F, Arcovito A, Giardina G, della Longa S, D'Angelo P, Rinaldo S.

Biometals. 2014 Aug;27(4):763-73. doi: 10.1007/s10534-014-9770-3. Epub 2014 Jul 10.

PMID:
25007853
32.

To move or not to move: subthalamic deep brain stimulation effects on implicit motor simulation.

Tomasino B, Marin D, Eleopra R, Rinaldo S, Cristian L, Marco M, Enrico B, Zanier M, Budai R, Mondani M, D'Auria S, Skrap M, Fabbro F.

Brain Res. 2014 Jul 29;1574:14-25. doi: 10.1016/j.brainres.2014.06.009. Epub 2014 Jun 13.

PMID:
24933326
33.

Paroxysmal itch caused by gain-of-function Nav1.7 mutation.

Devigili G, Eleopra R, Pierro T, Lombardi R, Rinaldo S, Lettieri C, Faber CG, Merkies IS, Waxman SG, Lauria G.

Pain. 2014 Sep;155(9):1702-7. doi: 10.1016/j.pain.2014.05.006. Epub 2014 May 10.

PMID:
24820863
34.

Microsubthalamotomy improves sleep in patients affected by advanced Parkinson's disease.

Merlino G, Lettieri C, Mondani M, Belgrado E, Devigili G, Mucchiut M, Rinaldo S, Craighero C, D'Auria S, Skrap M, Eleopra R.

Sleep Med. 2014 Jun;15(6):637-41. doi: 10.1016/j.sleep.2013.12.016. Epub 2014 Feb 28.

PMID:
24784787
35.

Chronic post-traumatic neuropathic pain of brachial plexus and upper limb: a new technique of peripheral nerve stimulation.

Stevanato G, Devigili G, Eleopra R, Fontana P, Lettieri C, Baracco C, Guida F, Rinaldo S, Bevilacqua M.

Neurosurg Rev. 2014 Jul;37(3):473-79; discussion 479-80. doi: 10.1007/s10143-014-0523-0. Epub 2014 Feb 21.

36.

The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.

Paiardini A, Aducci P, Cervoni L, Cutruzzolà F, Di Lucente C, Janson G, Pascarella S, Rinaldo S, Visconti S, Camoni L.

IUBMB Life. 2014 Jan;66(1):52-62. doi: 10.1002/iub.1239. Epub 2014 Jan 10.

37.

Emotion recognition in Parkinson's disease after subthalamic deep brain stimulation: differential effects of microlesion and STN stimulation.

Aiello M, Eleopra R, Lettieri C, Mondani M, D'Auria S, Belgrado E, Piani A, De Simone L, Rinaldo S, Rumiati RI.

Cortex. 2014 Feb;51:35-45. doi: 10.1016/j.cortex.2013.11.003. Epub 2013 Nov 19.

PMID:
24342106
38.

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain.

Giardina G, Paiardini A, Fernicola S, Franceschini S, Rinaldo S, Stelitano V, Cutruzzolà F.

PLoS One. 2013 Nov 22;8(11):e81324. doi: 10.1371/journal.pone.0081324. eCollection 2013.

39.

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG.

Stelitano V, Giardina G, Paiardini A, Castiglione N, Cutruzzolà F, Rinaldo S.

PLoS One. 2013 Sep 16;8(9):e74920. doi: 10.1371/journal.pone.0074920. eCollection 2013.

40.

The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.

Antoniani D, Rossi E, Rinaldo S, Bocci P, Lolicato M, Paiardini A, Raffaelli N, Cutruzzolà F, Landini P.

Appl Microbiol Biotechnol. 2013 Aug;97(16):7325-36. doi: 10.1007/s00253-013-4875-0. Epub 2013 Apr 14.

PMID:
23584245
41.

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy.

Stelitano V, Brandt A, Fernicola S, Franceschini S, Giardina G, Pica A, Rinaldo S, Sica F, Cutruzzolà F.

Nucleic Acids Res. 2013 Apr;41(7):e79. doi: 10.1093/nar/gkt028. Epub 2013 Jan 28.

42.

Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study.

Eleopra R, Montecucco C, Devigili G, Lettieri C, Rinaldo S, Verriello L, Pirazzini M, Caccin P, Rossetto O.

Clin Neurophysiol. 2013 May;124(5):999-1004. doi: 10.1016/j.clinph.2012.11.004. Epub 2012 Dec 13.

PMID:
23245668
43.

Nonmonotonic dynamics in Lifshitz-Slyozov-Wagner theory: Ostwald ripening in nanoparticle catalysts.

Rinaldo SG, Lee W, Stumper J, Eikerling M.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Oct;86(4 Pt 1):041601. Epub 2012 Oct 5.

PMID:
23214593
44.

Solvent accessibility in the distal heme pocket of the nitrosyl d(1)-heme complex of Pseudomonas stutzeri cd(1) nitrite reductase.

Radoul M, Barak Y, Rinaldo S, Cutruzzolà F, Pecht I, Goldfarb D.

Biochemistry. 2012 Nov 13;51(45):9192-201. doi: 10.1021/bi3011237. Epub 2012 Nov 2.

PMID:
23072349
45.

Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.

Chi CN, Haq SR, Rinaldo S, Dogan J, Cutruzzolà F, Engström Å, Gianni S, Lundström P, Jemth P.

Biochemistry. 2012 Nov 6;51(44):8971-9. doi: 10.1021/bi300792h. Epub 2012 Oct 23.

PMID:
23046383
46.

Deep brain stimulation: Subthalamic nucleus electrophysiological activity in awake and anesthetized patients.

Lettieri C, Rinaldo S, Devigili G, Pauletto G, Verriello L, Budai R, Fadiga L, Oliynyk A, Mondani M, D'Auria S, Skrap M, Eleopra R.

Clin Neurophysiol. 2012 Dec;123(12):2406-13. doi: 10.1016/j.clinph.2012.04.027. Epub 2012 Jun 7.

PMID:
22683113
47.

Unusual heme binding properties of the dissimilative nitrate respiration regulator, a bacterial nitric oxide sensor.

Rinaldo S, Castiglione N, Giardina G, Caruso M, Arcovito A, Longa SD, D'Angelo P, Cutruzzolà F.

Antioxid Redox Signal. 2012 Nov 1;17(9):1178-89. doi: 10.1089/ars.2011.4226. Epub 2012 Apr 27.

PMID:
22424265
48.

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease.

Castiglione N, Rinaldo S, Giardina G, Stelitano V, Cutruzzolà F.

Antioxid Redox Signal. 2012 Aug 15;17(4):684-716. doi: 10.1089/ars.2011.4196. Epub 2012 Mar 16. Review.

PMID:
22304560
49.

In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.

Daidone F, Florio R, Rinaldo S, Contestabile R, di Salvo ML, Cutruzzolà F, Bossa F, Paiardini A.

Eur J Med Chem. 2011 May;46(5):1616-21. doi: 10.1016/j.ejmech.2011.02.009. Epub 2011 Mar 2.

PMID:
21371789
50.

Dynamic hydrogen-bonding network in the distal pocket of the nitrosyl complex of Pseudomonas aeruginosa cd1 nitrite reductase.

Radoul M, Bykov D, Rinaldo S, Cutruzzolà F, Neese F, Goldfarb D.

J Am Chem Soc. 2011 Mar 9;133(9):3043-55. doi: 10.1021/ja109688w. Epub 2011 Feb 10.

PMID:
21309511

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