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Items: 1 to 50 of 125

1.

Trained immunity and atherosclerotic cardiovascular disease.

Riksen NP.

Curr Opin Lipidol. 2019 Oct;30(5):395-400. doi: 10.1097/MOL.0000000000000628.

PMID:
31335332
2.

Investigating the origin and evolution of cerebral small vessel disease: The RUN DMC - InTENse study.

Ter Telgte A, Wiegertjes K, Tuladhar AM, Noz MP, Marques JP, Gesierich B, Huebner M, Mutsaerts HM, Elias-Smale SE, Beelen MJ, Ropele S, Kessels RP, Riksen NP, Klijn CJ, Norris DG, Duering M, de Leeuw FE.

Eur Stroke J. 2018 Dec;3(4):369-378. doi: 10.1177/2396987318776088. Epub 2018 May 9.

3.

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

Bekkering S, Stiekema LCA, Bernelot Moens S, Verweij SL, Novakovic B, Prange K, Versloot M, Roeters van Lennep JE, Stunnenberg H, de Winther M, Stroes ESG, Joosten LAB, Netea MG, Riksen NP.

Cell Metab. 2019 Jul 2;30(1):1-2. doi: 10.1016/j.cmet.2019.05.014. Epub 2019 Jun 13.

PMID:
31204280
4.

Aldosterone induces trained immunity: the role of fatty acid synthesis.

van der Heijden CDCC, Keating ST, Groh L, Joosten LAB, Netea MG, Riksen NP.

Cardiovasc Res. 2019 May 22. pii: cvz137. doi: 10.1093/cvr/cvz137. [Epub ahead of print]

PMID:
31119285
5.

Remote ischaemic preconditioning does not modulate the systemic inflammatory response or renal tubular stress biomarkers after endotoxaemia in healthy human volunteers: a single-centre, mechanistic, randomised controlled trial.

Zwaag J, Beunders R, Warlé MC, Kellum JA, Riksen NP, Pickkers P, Kox M.

Br J Anaesth. 2019 Aug;123(2):177-185. doi: 10.1016/j.bja.2019.03.037. Epub 2019 May 10.

6.

Immunometabolism orchestrates training of innate immunity in atherosclerosis.

van Tuijl J, Joosten LAB, Netea MG, Bekkering S, Riksen NP.

Cardiovasc Res. 2019 Jul 1;115(9):1416-1424. doi: 10.1093/cvr/cvz107.

PMID:
31050710
7.

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes.

Mirea AM, Toonen EJM, van den Munckhof I, Munsterman ID, Tjwa ETTL, Jaeger M, Oosting M, Schraa K, Rutten JHW, van der Graaf M, Riksen NP, de Graaf J, Netea MG, Tack CJ, Chavakis T, Joosten LAB.

Mol Med. 2019 May 2;25(1):16. doi: 10.1186/s10020-019-0084-3.

8.

Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides.

Neidhart M, Pajak A, Laskari K, Riksen NP, Joosten LAB, Netea MG, Lutgens E, Stroes ESG, Ciurea A, Distler O, Grigorian M, Karouzakis E.

Front Immunol. 2019 Apr 15;10:791. doi: 10.3389/fimmu.2019.00791. eCollection 2019.

9.

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk.

Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M; LifeLines DEEP Cohort Study, BBMRI Metabolomics Consortium, Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J.

Circ Res. 2019 Jun 7;124(12):1808-1820. doi: 10.1161/CIRCRESAHA.118.314642. Epub 2019 Apr 11.

PMID:
30971183
10.

Effect of two dosages of sodium chloride intake on the blood pressure response to caffeinated coffee in humans in vivo.

Esselink AC, Bril LM, Langenhuijsen RW, Bilos A, Riksen NP, Rongen GA.

Int J Food Sci Nutr. 2019 Apr 10:1-6. doi: 10.1080/09637486.2019.1595541. [Epub ahead of print]

PMID:
30969142
11.

Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?"

Plat J, Baumgartner S, Vanmierlo T, Lütjohann D, Calkins KL, Burrin DG, Guthrie G, Thijs C, Te Velde AA, Vreugdenhil ACE, Sverdlov R, Garssen J, Wouters K, Trautwein EA, Wolfs TG, van Gorp C, Mulder MT, Riksen NP, Groen AK, Mensink RP.

Prog Lipid Res. 2019 Apr;74:87-102. doi: 10.1016/j.plipres.2019.02.003. Epub 2019 Feb 26. Review.

12.

Postural orthostatic tachycardia syndrome (POTS): a common but unfamiliar syndrome.

van der Zalm T, Alsma J, van de Poll SWE, Wessels MW, Riksen NP, Versmissen J.

Neth J Med. 2019 Jan;77(1):3-9.

13.

Trained immunity and diabetic vascular disease.

Thiem K, Stienstra R, Riksen NP, Keating ST.

Clin Sci (Lond). 2019 Jan 18;133(2):195-203. doi: 10.1042/CS20180905. Print 2019 Jan 31. Review.

PMID:
30659160
14.

Evaluation of Microvascular Injury in Revascularized Patients With ST-Segment-Elevation Myocardial Infarction Treated With Ticagrelor Versus Prasugrel.

van Leeuwen MAH, van der Hoeven NW, Janssens GN, Everaars H, Nap A, Lemkes JS, de Waard GA, van de Ven PM, van Rossum AC, Ten Cate TJF, Piek JJ, von Birgelen C, Escaned J, Valgimigli M, Diletti R, Riksen NP, van Mieghem NM, Nijveldt R, van Royen N.

Circulation. 2019 Jan 29;139(5):636-646. doi: 10.1161/CIRCULATIONAHA.118.035931.

PMID:
30586720
15.

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease.

Noz MP, Ter Telgte A, Wiegertjes K, Joosten LAB, Netea MG, de Leeuw FE, Riksen NP.

Stroke. 2018 Dec;49(12):2910-2917. doi: 10.1161/STROKEAHA.118.023192.

PMID:
30571420
16.

Multidisciplinary care for people with Parkinson's disease: the new kids on the block!

Radder DLM, de Vries NM, Riksen NP, Diamond SJ, Gross D, Gold DR, Heesakkers J, Henderson E, Hommel ALAJ, Lennaerts HH, Busch J, Dorsey RE, Andrejack J, Bloem BR.

Expert Rev Neurother. 2019 Feb;19(2):145-157. doi: 10.1080/14737175.2019.1561285. Epub 2019 Jan 9.

PMID:
30570362
17.

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2.

Kurstjens S, de Baaij JHF, Overmars-Bos C, van den Munckhof ICL, Garzero V, de Vries MA, Burggraaf B, van Diepen JA, Riksen NP, Rutten JHW, Netea MG, Castro Cabezas M, Bindels RJM, Ashcroft FM, Tack CJJ, Hoenderop JGJ.

Diabetologia. 2019 Feb;62(2):311-321. doi: 10.1007/s00125-018-4771-3. Epub 2018 Nov 13.

18.

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology.

Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, Bayes-Genis A, Brutsaert D, Bugger H, Clarke K, Cosentino F, De Keulenaer G, Dei Cas A, González A, Huelsmann M, Iaccarino G, Lunde IG, Lyon AR, Pollesello P, Rena G, Riksen NP, Rosano G, Staels B, van Laake LW, Wanner C, Farmakis D, Filippatos G, Ruschitzka F, Seferovic P, de Boer RA, Heymans S.

Eur Heart J. 2018 Dec 21;39(48):4243-4254. doi: 10.1093/eurheartj/ehy596. No abstract available.

19.

Getting to the marrow of trained immunity.

Groh L, Netea MG, Riksen NP, Keating ST.

Epigenomics. 2018 Sep;10(9):1151-1154. doi: 10.2217/epi-2018-0098. No abstract available.

PMID:
30238777
20.

Be aware, innate immune cells remember.

Riksen NP, Netea MG.

Aging (Albany NY). 2018 Sep 12;10(9):2218-2219. doi: 10.18632/aging.101552. No abstract available.

21.

Role of gut microbiota in chronic low-grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies.

van den Munckhof ICL, Kurilshikov A, Ter Horst R, Riksen NP, Joosten LAB, Zhernakova A, Fu J, Keating ST, Netea MG, de Graaf J, Rutten JHW.

Obes Rev. 2018 Dec;19(12):1719-1734. doi: 10.1111/obr.12750. Epub 2018 Aug 24.

PMID:
30144260
22.

Metabolism of innate immune cells: impact on atherosclerosis.

Riksen NP, Stienstra R.

Curr Opin Lipidol. 2018 Oct;29(5):359-367. doi: 10.1097/MOL.0000000000000539.

PMID:
30020200
23.

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

Kiers D, Wielockx B, Peters E, van Eijk LT, Gerretsen J, John A, Janssen E, Groeneveld R, Peters M, Damen L, Meneses AM, Krüger A, Langereis JD, Zomer AL, Blackburn MR, Joosten LA, Netea MG, Riksen NP, van der Hoeven JG, Scheffer GJ, Eltzschig HK, Pickkers P, Kox M.

EBioMedicine. 2018 Jul;33:144-156. doi: 10.1016/j.ebiom.2018.06.021. Epub 2018 Jul 4.

24.

The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis.

van der Heijden CDCC, Deinum J, Joosten LAB, Netea MG, Riksen NP.

Cardiovasc Res. 2018 Jun 1;114(7):944-953. doi: 10.1093/cvr/cvy092. Review.

PMID:
29668907
25.

Correction: A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

Hesen NA, Riksen NP, Aalders B, Brouwer MAE, Ritskes-Hoitinga M, El Messaoudi S, Wever KE.

PLoS One. 2018 Apr 9;13(4):e0195858. doi: 10.1371/journal.pone.0195858. eCollection 2018.

26.

Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes.

Damen MSMA, Dos Santos JC, Hermsen R, Adam van der Vliet J, Netea MG, Riksen NP, Dinarello CA, Joosten LAB, Heinhuis B.

Atherosclerosis. 2018 Apr;271:193-202. doi: 10.1016/j.atherosclerosis.2018.02.027. Epub 2018 Mar 2.

27.

The acute effect of black tea consumption on resistance artery endothelial function in healthy subjects. A randomized controlled trial.

Greyling A, Wolters TLC, de Bresser DM, Roerink SHPP, Riksen NP, Mulder TP, Rowson MJ, Hopman MT, Thijssen DHJ.

Clin Nutr ESPEN. 2018 Feb;23:41-47. doi: 10.1016/j.clnesp.2017.10.011. Epub 2017 Nov 8.

PMID:
29460812
28.

Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

Leentjens J, Bekkering S, Joosten LAB, Netea MG, Burgner DP, Riksen NP.

Circ Res. 2018 Mar 2;122(5):664-669. doi: 10.1161/CIRCRESAHA.117.312465. Epub 2018 Jan 24. Review.

PMID:
29367213
29.

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E.

Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013.

30.

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

Bekkering S, Arts RJW, Novakovic B, Kourtzelis I, van der Heijden CDCC, Li Y, Popa CD, Ter Horst R, van Tuijl J, Netea-Maier RT, van de Veerdonk FL, Chavakis T, Joosten LAB, van der Meer JWM, Stunnenberg H, Riksen NP, Netea MG.

Cell. 2018 Jan 11;172(1-2):135-146.e9. doi: 10.1016/j.cell.2017.11.025.

31.

Epigenetics in diabetic nephropathy, immunity and metabolism.

Keating ST, van Diepen JA, Riksen NP, El-Osta A.

Diabetologia. 2018 Jan;61(1):6-20. doi: 10.1007/s00125-017-4490-1. Epub 2017 Nov 11. Review.

32.

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard BG, Neidhart M, Stroes ESG, Catapano AL, Bekkering S.

Eur Heart J. 2018 Oct 7;39(38):3521-3527. doi: 10.1093/eurheartj/ehx581. Erratum in: Eur Heart J. 2018 Jun 14;39(23):2182.

33.

Epigenetics and Trained Immunity.

van der Heijden CDCC, Noz MP, Joosten LAB, Netea MG, Riksen NP, Keating ST.

Antioxid Redox Signal. 2018 Oct 10;29(11):1023-1040. doi: 10.1089/ars.2017.7310. Epub 2017 Nov 21.

34.

Monocyte and macrophage immunometabolism in atherosclerosis.

Groh L, Keating ST, Joosten LAB, Netea MG, Riksen NP.

Semin Immunopathol. 2018 Feb;40(2):203-214. doi: 10.1007/s00281-017-0656-7. Epub 2017 Oct 2. Review.

35.

A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

Hesen NA, Riksen NP, Aalders B, Brouwer MA, Ritskes-Hoitinga M, El Messaoudi S, Wever KE.

PLoS One. 2017 Aug 23;12(8):e0183664. doi: 10.1371/journal.pone.0183664. eCollection 2017. Review. Erratum in: PLoS One. 2018 Apr 9;13(4):e0195858.

36.

A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.

Kiers D, van der Heijden WA, van Ede L, Gerretsen J, de Mast Q, van der Ven AJ, El Messaoudi S, Rongen GA, Gomes M, Kox M, Pickkers P, Riksen NP.

Thromb Haemost. 2017 Aug 30;117(9):1798-1807. doi: 10.1160/TH16-10-0799. Epub 2017 Jul 6.

PMID:
28692111
37.

Specific and Complex Reprogramming of Cellular Metabolism in Myeloid Cells during Innate Immune Responses.

Stienstra R, Netea-Maier RT, Riksen NP, Joosten LAB, Netea MG.

Cell Metab. 2017 Jul 5;26(1):142-156. doi: 10.1016/j.cmet.2017.06.001. Review.

38.

Planarians SET New Paths for Innate Immune Memory.

Keating ST, Riksen NP, Netea MG.

EBioMedicine. 2017 Jun;20:7-8. doi: 10.1016/j.ebiom.2017.05.007. Epub 2017 May 5. No abstract available.

39.

Correction for Bekkering et al., "In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes".

Bekkering S, Blok BA, Joosten LAB, Riksen NP, van Crevel R, Netea MG.

Clin Vaccine Immunol. 2017 May 5;24(5). pii: e00096-17. doi: 10.1128/CVI.00096-17. Print 2017 May. No abstract available.

40.

Plasma galectin-3 concentrations in patients with primary aldosteronism.

van den Berg TNAD, Meijers WC, Donders ART, Van Herwaarden AE, Rongen GA, de Boer RA, Deinum J, Riksen NP.

J Hypertens. 2017 Sep;35(9):1849-1856. doi: 10.1097/HJH.0000000000001383.

PMID:
28403043
41.

Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans.

Maessen MFH, van Mil ACCM, Straathof Y, Riksen NP, Rongen GAPJM, Hopman MTE, Eijsvogels TMH, Thijssen DHJ.

Am J Physiol Regul Integr Comp Physiol. 2017 May 1;312(5):R828-R834. doi: 10.1152/ajpregu.00466.2016. Epub 2017 Mar 15.

42.

Characterization of a model of systemic inflammation in humans in vivo elicited by continuous infusion of endotoxin.

Kiers D, Koch RM, Hamers L, Gerretsen J, Thijs EJ, van Ede L, Riksen NP, Kox M, Pickkers P.

Sci Rep. 2017 Jan 5;7:40149. doi: 10.1038/srep40149.

43.

[Ischemic stroke in young women].

Ekker MS, Wermer MJ, Riksen NP, Klijn CJ, de Leeuw FE.

Ned Tijdschr Geneeskd. 2016;160:D689. Review. Dutch.

PMID:
27966404
44.

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.

Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Gonçalves LG, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk FL, Williams DL, van der Meer JW, Logie C, O'Neill LA, Dinarello CA, Riksen NP, van Crevel R, Clish C, Notebaart RA, Joosten LA, Stunnenberg HG, Xavier RJ, Netea MG.

Cell Metab. 2016 Dec 13;24(6):807-819. doi: 10.1016/j.cmet.2016.10.008. Epub 2016 Nov 17.

45.

[Hypertension due to fibromuscular dysplasia: look for additional disease sites].

Maas ML, Kroese JM, Bredie SJ, Postma CT, de Leeuw FE, Schultze Kool LJ, Riksen NP.

Ned Tijdschr Geneeskd. 2016;160:D288. Dutch.

PMID:
27827286
46.

In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes.

Bekkering S, Blok BA, Joosten LA, Riksen NP, van Crevel R, Netea MG.

Clin Vaccine Immunol. 2016 Dec 5;23(12):926-933. Print 2016 Dec. Erratum in: Clin Vaccine Immunol. 2017 May 5;24(5):.

47.

Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo.

Bekkering S, van den Munckhof I, Nielen T, Lamfers E, Dinarello C, Rutten J, de Graaf J, Joosten LA, Netea MG, Gomes ME, Riksen NP.

Atherosclerosis. 2016 Nov;254:228-236. doi: 10.1016/j.atherosclerosis.2016.10.019. Epub 2016 Oct 12.

48.

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans.

van der Valk FM, Bekkering S, Kroon J, Yeang C, Van den Bossche J, van Buul JD, Ravandi A, Nederveen AJ, Verberne HJ, Scipione C, Nieuwdorp M, Joosten LA, Netea MG, Koschinsky ML, Witztum JL, Tsimikas S, Riksen NP, Stroes ES.

Circulation. 2016 Aug 23;134(8):611-24. doi: 10.1161/CIRCULATIONAHA.116.020838. Epub 2016 Aug 5.

49.

Diabetes propels the risk for cardiovascular disease: sweet monocytes becoming aggressive?

van Diepen JA, Thiem K, Stienstra R, Riksen NP, Tack CJ, Netea MG.

Cell Mol Life Sci. 2016 Dec;73(24):4675-4684. Epub 2016 Jul 28. Review.

50.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

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