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Development of Effective Therapeutics Targeting HER3 for Cancer Treatment.

Liu X, Liu S, Lyu H, Riker AI, Zhang Y, Liu B.

Biol Proced Online. 2019 Mar 19;21:5. doi: 10.1186/s12575-019-0093-1. eCollection 2019. Review.


Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.

Nghiem P, Bhatia S, Lipson EJ, Sharfman WH, Kudchadkar RR, Brohl AS, Friedlander PA, Daud A, Kluger HM, Reddy SA, Boulmay BC, Riker AI, Burgess MA, Hanks BA, Olencki T, Margolin K, Lundgren LM, Soni A, Ramchurren N, Church C, Park SY, Shinohara MM, Salim B, Taube JM, Bird SR, Ibrahim N, Fling SP, Homet Moreno B, Sharon E, Cheever MA, Topalian SL.

J Clin Oncol. 2019 Mar 20;37(9):693-702. doi: 10.1200/JCO.18.01896. Epub 2019 Feb 6.


A novel patient-derived xenograft model for claudin-low triple-negative breast cancer.

Matossian MD, Burks HE, Bowles AC, Elliott S, Hoang VT, Sabol RA, Pashos NC, O'Donnell B, Miller KS, Wahba BM, Bunnell BA, Moroz K, Zea AH, Jones SD, Ochoa AC, Al-Khami AA, Hossain F, Riker AI, Rhodes LV, Martin EC, Miele L, Burow ME, Collins-Burow BM.

Breast Cancer Res Treat. 2018 Jun;169(2):381-390. doi: 10.1007/s10549-018-4685-2. Epub 2018 Feb 1.


Current clinical trials for melanoma vaccines: where do we stand?

Riker AI, Bisgaard E.

Melanoma Manag. 2016 Dec;3(4):255-257. doi: 10.2217/mmt-2016-0009. Epub 2016 Nov 30. No abstract available.


Clinical Utility of the 12-Gene DCIS Score Assay: Impact on Radiotherapy Recommendations for Patients with Ductal Carcinoma In Situ.

Manders JB, Kuerer HM, Smith BD, McCluskey C, Farrar WB, Frazier TG, Li L, Leonard CE, Carter DL, Chawla S, Medeiros LE, Guenther JM, Castellini LE, Buchholz DJ, Mamounas EP, Wapnir IL, Horst KC, Chagpar A, Evans SB, Riker AI, Vali FS, Solin LJ, Jablon L, Recht A, Sharma R, Lu R, Sing AP, Hwang ES, White J; Study investigators and study participants.

Ann Surg Oncol. 2017 Mar;24(3):660-668. doi: 10.1245/s10434-016-5583-7. Epub 2016 Oct 4.


Palliative Resection of a Giant Mesenteric Desmoid Tumor.

Sugrue JJ, Cohen SB, Marshall RM, Riker AI.

Ochsner J. 2015 Winter;15(4):468-72.


A Case of Male Breast Cancer with a BRCA Gene Mutation.

Benjamin MA, Riker AI.

Ochsner J. 2015 Winter;15(4):448-51.


Anesthetic Considerations for Intraoperative Radiation Therapy.

Glynn KM, Riker AI.

Ochsner J. 2015 Winter;15(4):438-40. Review.


In Regard to Vaidya et al.

Wazer DE, Hepel JT, Riker AI, Harness JK, Chung C, Khan AJ, Offersen BV, Poortmans P, Taghian A.

Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):952-953. doi: 10.1016/j.ijrobp.2015.05.032. Epub 2015 Jul 14. No abstract available.


A Case of Severe Anaphylactic Reaction Secondary to Isosulfan Blue Dye Injection.

Ortiz D, Alvikas J, Riker AI.

Ochsner J. 2015 Summer;15(2):183-6.


Human malignant melanoma-derived progestagen-associated endometrial protein immunosuppresses T lymphocytes in vitro.

Ren S, Chai L, Wang C, Li C, Ren Q, Yang L, Wang F, Qiao Z, Li W, He M, Riker AI, Han Y, Yu Q.

PLoS One. 2015 Mar 18;10(3):e0119038. doi: 10.1371/journal.pone.0119038. eCollection 2015.


Recurrent angiomatoid fibrous histiocytoma: a case report and review of the literature.

Huerter ME, Hammadeh R, Zhou Q, Riker AI.

Ochsner J. 2014 Fall;14(3):441-4.


Primary amyloidosis of the breast presenting as a solitary nodule: case report and review of the literature.

Huerter ME, Hammadeh R, Zhou Q, Weisberg A, Riker AI.

Ochsner J. 2014 Summer;14(2):282-6.


Combination immunotherapy for high-risk resected and metastatic melanoma patients.

Riker AI, Rossi GR, Masih P, Alsfeld LC, Denham F, Tennant L, Ramsey WJ, Vahanian NN, Link CJ.

Ochsner J. 2014 Summer;14(2):164-74.


Radiotherapy for breast cancer, the TARGIT-A trial.

Harness JK, Silverstein MJ, Wazer DE, Riker AI.

Lancet. 2014 May 17;383(9930):1718-9. doi: 10.1016/S0140-6736(14)60829-1. No abstract available.


Neuropilin-2 gene expression correlates with malignant progression in cutaneous melanoma.

Rossi M, Tuck J, Kim OJ, Panova I, Symanowski JT, Mahalingam M, Riker AI, Alani RM, Ryu B.

Br J Dermatol. 2014 Aug;171(2):403-8. doi: 10.1111/bjd.12801. Epub 2014 Jun 11.


Up-regulation of miR-182 expression after epigenetic modulation of human melanoma cells.

Liu S, Howell PM, Riker AI.

Ann Surg Oncol. 2013 May;20(5):1745-52. doi: 10.1245/s10434-012-2467-3. Epub 2012 Jun 30.


Location, location, location: the BRMS1 protein and melanoma progression.

Riker AI, Samant RS.

BMC Med. 2012 Feb 22;10:19. doi: 10.1186/1741-7015-10-19. Review.


Aquaporins mediate the chemoresistance of human melanoma cells to arsenite.

Gao L, Gao Y, Li X, Howell P, Kumar R, Su X, Vlassov AV, Piazza GA, Riker AI, Sun D, Xi Y.

Mol Oncol. 2012 Feb;6(1):81-7. doi: 10.1016/j.molonc.2011.11.001. Epub 2011 Nov 13.


Overexpression of the progestagen-associated endometrial protein gene is associated with microphthalmia-associated transcription factor in human melanoma.

Ren S, Howell PM Jr, Han Y, Wang J, Liu M, Wang Y, Quan G, Du W, Fang L, Riker AI.

Ochsner J. 2011 Fall;11(3):212-9.


Use of ipilimumab in melanoma.

Rivere A, Bourgeois DJ, Riker AI.

Immunotherapy. 2011 Aug;3(8):927-30. doi: 10.2217/imt.11.77. No abstract available.


Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer.

Kao WH, Riker AI, Kushwaha DS, Ng K, Enkemann SA, Jove R, Buettner R, Zinn PO, Sánchez NP, Villa JL, D'Andrea AD, Sánchez JL, Kennedy RD, Chen CC, Matta JL.

J Invest Dermatol. 2011 Oct;131(10):2139-42. doi: 10.1038/jid.2011.181. Epub 2011 Jun 23. No abstract available.


MicroRNA in Melanoma.

Howell PM Jr, Li X, Riker AI, Xi Y.

Ochsner J. 2010 Summer;10(2):83-92.


The epidemiology, prevention, and detection of melanoma.

Riker AI, Zea N, Trinh T.

Ochsner J. 2010 Summer;10(2):56-65.


From the Editor's Desk.

Riker AI.

Ochsner J. 2010 Summer;10(2):55. No abstract available.

Free PMC Article

Emerging metabolic targets in cancer therapy.

Zhao Y, Liu H, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1844-60. Review.


MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.

Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M.

J Biol Chem. 2010 Jul 9;285(28):21496-507. doi: 10.1074/jbc.M109.083337. Epub 2010 May 11.


Elevated osteopontin levels in metastatic melanoma correlate with epigenetic silencing of breast cancer metastasis suppressor 1.

Metge BJ, Liu S, Riker AI, Fodstad O, Samant RS, Shevde LA.

Oncology. 2010;78(1):75-86. doi: 10.1159/000292363. Epub 2010 Mar 6.


Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol.

Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M.

Mol Cancer. 2010 Feb 9;9:33. doi: 10.1186/1476-4598-9-33.


Cystatin E/M suppresses legumain activity and invasion of human melanoma.

Briggs JJ, Haugen MH, Johansen HT, Riker AI, Abrahamson M, Fodstad Ø, Maelandsmo GM, Solberg R.

BMC Cancer. 2010 Jan 15;10:17. doi: 10.1186/1471-2407-10-17.


A personalized microRNA microarray normalization method using a logistic regression model.

Wang B, Wang XF, Howell P, Qian X, Huang K, Riker AI, Ju J, Xi Y.

Bioinformatics. 2010 Jan 15;26(2):228-34. doi: 10.1093/bioinformatics/btp655. Epub 2009 Nov 23.


Functional characterization of the progestagen-associated endometrial protein gene in human melanoma.

Ren S, Liu S, Howell PM Jr, Zhang G, Pannell L, Samant R, Shevde-Samant L, Tucker JA, Fodstad O, Riker AI.

J Cell Mol Med. 2010 Jun;14(6B):1432-42. doi: 10.1111/j.1582-4934.2009.00922.x. Epub 2009 Oct 3.


Epigenetics in human melanoma.

Howell PM Jr, Liu S, Ren S, Behlen C, Fodstad O, Riker AI.

Cancer Control. 2009 Jul;16(3):200-18. Review.


The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.

Das S, Harris LG, Metge BJ, Liu S, Riker AI, Samant RS, Shevde LA.

J Biol Chem. 2009 Aug 21;284(34):22888-97. doi: 10.1074/jbc.M109.021949. Epub 2009 Jun 25.


Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma.

Liu S, Howell P, Ren S, Fodstad O, Zhang G, Samant R, Shevde L, Xi Y, Pannell LK, Riker AI.

Clin Exp Metastasis. 2009;26(7):739-49. doi: 10.1007/s10585-009-9273-8. Epub 2009 Jun 2.


Current concepts in biobanking: development and implementation of a tissue repository.

Shevde LA, Riker AI.

Front Biosci (Schol Ed). 2009 Jun 1;1:188-93. Review.


The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma.

Liu S, Howell P, Ren S, Fodstad O, Riker AI.

BMC Cancer. 2009 May 27;9:162. doi: 10.1186/1471-2407-9-162.


Carcinosarcoma of the breast: two case reports and review of the literature.

Esses KM, Hagmaier RM, Blanchard SA, Lazarchick JJ, Riker AI.

Cases J. 2009 Jan 6;2(1):15. doi: 10.1186/1757-1626-2-15.


Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma.

Daud AI, DeConti RC, Andrews S, Urbas P, Riker AI, Sondak VK, Munster PN, Sullivan DM, Ugen KE, Messina JL, Heller R.

J Clin Oncol. 2008 Dec 20;26(36):5896-903. doi: 10.1200/JCO.2007.15.6794. Epub 2008 Nov 24.


Successful removal of a giant intrathoracic lipoma: a case report and review of the literature.

Hagmaier RM, Nelson GA, Daniels LJ, Riker AI.

Cases J. 2008 Aug 12;1(1):87. doi: 10.1186/1757-1626-1-87.


Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling.

Liu S, Ren S, Howell P, Fodstad O, Riker AI.

Pigment Cell Melanoma Res. 2008 Oct;21(5):545-58. doi: 10.1111/j.1755-148X.2008.00484.x. Epub 2007 Jun 28.


The impact of genomics in understanding human melanoma progression and metastasis.

Ren S, Liu S, Howell P Jr, Xi Y, Enkemann SA, Ju J, Riker AI.

Cancer Control. 2008 Jul;15(3):202-15. Review.


Activated stat-3 in melanoma.

Messina JL, Yu H, Riker AI, Munster PN, Jove RL, Daud AI.

Cancer Control. 2008 Jul;15(3):196-201.


Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor.

Daud AI, Mirza N, Lenox B, Andrews S, Urbas P, Gao GX, Lee JH, Sondak VK, Riker AI, Deconti RC, Gabrilovich D.

J Clin Oncol. 2008 Jul 1;26(19):3235-41. doi: 10.1200/JCO.2007.13.9048.


The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis.

Riker AI, Enkemann SA, Fodstad O, Liu S, Ren S, Morris C, Xi Y, Howell P, Metge B, Samant RS, Shevde LA, Li W, Eschrich S, Daud A, Ju J, Matta J.

BMC Med Genomics. 2008 Apr 28;1:13. doi: 10.1186/1755-8794-1-13.


Full-thickness grafts procured from skin overlying the sentinel lymph node basin; reconstruction of primary cutaneous malignancy excision defects.

Lewis JM, Zager JS, Yu D, Pelaez D, Riker AI, Dessureault S, Cruse CW, Reintgen DS, Puleo CA, Sondak VK.

Ann Surg Oncol. 2008 Jun;15(6):1733-40. doi: 10.1245/s10434-008-9887-0. Epub 2008 Apr 1.


Comparative methodologies of regulatory T cell depletion in a murine melanoma model.

Matsushita N, Pilon-Thomas SA, Martin LM, Riker AI.

J Immunol Methods. 2008 Apr 20;333(1-2):167-79. doi: 10.1016/j.jim.2008.01.012. Epub 2008 Feb 13.


Significance of sentinel lymph node micrometastases in human breast cancer.

Cox CE, Kiluk JV, Riker AI, Cox JM, Allred N, Ramos DC, Dupont EL, Vrcel V, Diaz N, Boulware D.

J Am Coll Surg. 2008 Feb;206(2):261-8. doi: 10.1016/j.jamcollsurg.2007.08.024. Epub 2007 Dec 11.


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