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Items: 24


Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator.

Riglar DT, Richmond DL, Potvin-Trottier L, Verdegaal AA, Naydich AD, Bakshi S, Leoncini E, Lyon LG, Paulsson J, Silver PA.

Nat Commun. 2019 Oct 11;10(1):4665. doi: 10.1038/s41467-019-12638-z.


Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium.

Ziesack M, Gibson T, Oliver JKW, Shumaker AM, Hsu BB, Riglar DT, Giessen TW, DiBenedetto NV, Bry L, Way JC, Silver PA, Gerber GK.

mSystems. 2019 Aug 13;4(4). pii: e00352-19. doi: 10.1128/mSystems.00352-19.


Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface.

Naydich AD, Nangle SN, Bues JJ, Trivedi D, Nissar N, Inniss MC, Niederhuber MJ, Way JC, Silver PA, Riglar DT.

mSystems. 2019 Jun 11;4(4). pii: e00125-19. doi: 10.1128/mSystems.00125-19.


Engineering bacteria for diagnostic and therapeutic applications.

Riglar DT, Silver PA.

Nat Rev Microbiol. 2018 Apr;16(4):214-225. doi: 10.1038/nrmicro.2017.172. Epub 2018 Feb 5. Review.


Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation.

Riglar DT, Giessen TW, Baym M, Kerns SJ, Niederhuber MJ, Bronson RT, Kotula JW, Gerber GK, Way JC, Silver PA.

Nat Biotechnol. 2017 Jul;35(7):653-658. doi: 10.1038/nbt.3879. Epub 2017 May 29.


Malaria Parasite Invasion: Achieving Superb Resolution.

Baum J, Richard D, Riglar DT.

Cell Host Microbe. 2017 Mar 8;21(3):294-296. doi: 10.1016/j.chom.2017.02.006. Review.


Localisation-based imaging of malarial antigens during erythrocyte entry reaffirms a role for AMA1 but not MTRAP in invasion.

Riglar DT, Whitehead L, Cowman AF, Rogers KL, Baum J.

J Cell Sci. 2016 Jan 1;129(1):228-42. doi: 10.1242/jcs.177741. Epub 2015 Nov 24.


Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites.

Olshina MA, Angrisano F, Marapana DS, Riglar DT, Bane K, Wong W, Catimel B, Yin MX, Holmes AB, Frischknecht F, Kovar DR, Baum J.

Malar J. 2015 Jul 18;14:280. doi: 10.1186/s12936-015-0801-5.


Membrane-wrapping contributions to malaria parasite invasion of the human erythrocyte.

Dasgupta S, Auth T, Gov NS, Satchwell TJ, Hanssen E, Zuccala ES, Riglar DT, Toye AM, Betz T, Baum J, Gompper G.

Biophys J. 2014 Jul 1;107(1):43-54. doi: 10.1016/j.bpj.2014.05.024.


Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum.

Healer J, Thompson JK, Riglar DT, Wilson DW, Chiu YH, Miura K, Chen L, Hodder AN, Long CA, Hansen DS, Baum J, Cowman AF.

PLoS One. 2013 Sep 10;8(9):e72504. doi: 10.1371/journal.pone.0072504. eCollection 2013.


Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion.

Hanssen E, Dekiwadia C, Riglar DT, Rug M, Lemgruber L, Cowman AF, Cyrklaff M, Kudryashev M, Frischknecht F, Baum J, Ralph SA.

Cell Microbiol. 2013 Sep;15(9):1457-72. doi: 10.1111/cmi.12132. Epub 2013 Mar 22.


Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes.

Riglar DT, Rogers KL, Hanssen E, Turnbull L, Bullen HE, Charnaud SC, Przyborski J, Gilson PR, Whitchurch CB, Crabb BS, Baum J, Cowman AF.

Nat Commun. 2013;4:1415. doi: 10.1038/ncomms2449.


Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast.

Lemgruber L, Kudryashev M, Dekiwadia C, Riglar DT, Baum J, Stahlberg H, Ralph SA, Frischknecht F.

Malar J. 2013 Jan 19;12:25. doi: 10.1186/1475-2875-12-25.


Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite.

Zuccala ES, Gout AM, Dekiwadia C, Marapana DS, Angrisano F, Turnbull L, Riglar DT, Rogers KL, Whitchurch CB, Ralph SA, Speed TP, Baum J.

PLoS One. 2012;7(9):e46160. doi: 10.1371/journal.pone.0046160. Epub 2012 Sep 25.


Spatial localisation of actin filaments across developmental stages of the malaria parasite.

Angrisano F, Riglar DT, Sturm A, Volz JC, Delves MJ, Zuccala ES, Turnbull L, Dekiwadia C, Olshina MA, Marapana DS, Wong W, Mollard V, Bradin CH, Tonkin CJ, Gunning PW, Ralph SA, Whitchurch CB, Sinden RE, Cowman AF, McFadden GI, Baum J.

PLoS One. 2012;7(2):e32188. doi: 10.1371/journal.pone.0032188. Epub 2012 Feb 28.


Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX).

Bullen HE, Charnaud SC, Kalanon M, Riglar DT, Dekiwadia C, Kangwanrangsan N, Torii M, Tsuboi T, Baum J, Ralph SA, Cowman AF, de Koning-Ward TF, Crabb BS, Gilson PR.

J Biol Chem. 2012 Mar 9;287(11):7871-84. doi: 10.1074/jbc.M111.328591. Epub 2012 Jan 17.


An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum.

Chen L, Lopaticki S, Riglar DT, Dekiwadia C, Uboldi AD, Tham WH, O'Neill MT, Richard D, Baum J, Ralph SA, Cowman AF.

PLoS Pathog. 2011 Sep;7(9):e1002199. doi: 10.1371/journal.ppat.1002199. Epub 2011 Sep 1.


Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains.

Triglia T, Chen L, Lopaticki S, Dekiwadia C, Riglar DT, Hodder AN, Ralph SA, Baum J, Cowman AF.

PLoS Pathog. 2011 Jun;7(6):e1002075. doi: 10.1371/journal.ppat.1002075. Epub 2011 Jun 16.


Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1.

Wong W, Skau CT, Marapana DS, Hanssen E, Taylor NL, Riglar DT, Zuccala ES, Angrisano F, Lewis H, Catimel B, Clarke OB, Kershaw NJ, Perugini MA, Kovar DR, Gulbis JM, Baum J.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9869-74. doi: 10.1073/pnas.1018927108. Epub 2011 May 31.


Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte.

Riglar DT, Richard D, Wilson DW, Boyle MJ, Dekiwadia C, Turnbull L, Angrisano F, Marapana DS, Rogers KL, Whitchurch CB, Beeson JG, Cowman AF, Ralph SA, Baum J.

Cell Host Microbe. 2011 Jan 20;9(1):9-20. doi: 10.1016/j.chom.2010.12.003.


Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development.

Boyle MJ, Wilson DW, Richards JS, Riglar DT, Tetteh KK, Conway DJ, Ralph SA, Baum J, Beeson JG.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14378-83. doi: 10.1073/pnas.1009198107. Epub 2010 Jul 26.


Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.

Richard D, MacRaild CA, Riglar DT, Chan JA, Foley M, Baum J, Ralph SA, Norton RS, Cowman AF.

J Biol Chem. 2010 May 7;285(19):14815-22. doi: 10.1074/jbc.M109.080770. Epub 2010 Mar 12.


Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.

Fletcher JI, Meusburger S, Hawkins CJ, Riglar DT, Lee EF, Fairlie WD, Huang DC, Adams JM.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18081-7. doi: 10.1073/pnas.0808691105. Epub 2008 Nov 3. Erratum in: Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1678.

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