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Items: 21


iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice.

Prado CM, Righetti RF, Lopes FDTQDS, Leick EA, Arantes-Costa FM, de Almeida FM, Saldiva PHN, Mauad T, Tibério IFLC, Martins MA.

Pulm Med. 2019 Mar 11;2019:4781528. doi: 10.1155/2019/4781528. eCollection 2019.


Extracellular Matrix Component Remodeling in Respiratory Diseases: What Has Been Found in Clinical and Experimental Studies?

Ito JT, Lourenço JD, Righetti RF, Tibério IFLC, Prado CM, Lopes FDTQS.

Cells. 2019 Apr 11;8(4). pii: E342. doi: 10.3390/cells8040342. Review.


A Guinea Pig Model of Airway Smooth Muscle Hyperreactivity Induced by Chronic Allergic Lung Inflammation: Contribution of Epithelium and Oxidative Stress.

Vasconcelos LHC, Silva MDCC, Costa AC, de Oliveira GA, de Souza ILL, Queiroga FR, Araujo LCDC, Cardoso GA, Righetti RF, Silva AS, da Silva PM, Carvalho CRO, Vieira GC, Tibério IFLC, Cavalcante FA, da Silva BA.

Front Pharmacol. 2019 Jan 24;9:1547. doi: 10.3389/fphar.2018.01547. eCollection 2018.


Author Correction: Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice.

de Genaro IS, de Almeida FM, Hizume-Kunzler DC, Moriya HT, Silva RA, Cruz JCG, Lopes RB, Righetti RF, de Paula Vieira R, Saiki M, Martins MA, Tibério IFLC, Arantes-Costa FM, Saraiva-Romanholo BM.

Sci Rep. 2018 Dec 12;8(1):17899. doi: 10.1038/s41598-018-36667-8.


A plant proteinase inhibitor from Enterolobium contortisiliquum attenuates airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.

Rodrigues APD, Bortolozzo ASS, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, Santana FPR, de Brito MV, Bonturi CR, Nunes NNDS, Prado CM, Leick EA, Oliva MLV, Martins MA, Righetti RF, Tibério IFLC.

Histol Histopathol. 2019 May;34(5):537-552. doi: 10.14670/HH-18-059. Epub 2018 Nov 8.


The Plant Proteinase Inhibitor CrataBL Plays a Role in Controlling Asthma Response in Mice.

Bortolozzo ASS, Rodrigues APD, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, de Brito MV, Ferreira RDS, Correia MTDS, Paiva PMG, Prado CM, Leick EA, Oliva MLV, Martins MA, Ruiz-Schutz VC, Righetti RF, Tibério IFLC.

Biomed Res Int. 2018 Oct 1;2018:9274817. doi: 10.1155/2018/9274817. eCollection 2018.


Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice.

Righetti RF, Dos Santos TM, Camargo LDN, Aristóteles LRCRB, Fukuzaki S, de Souza FCR, Santana FPR, de Agrela MVR, Cruz MM, Alonso-Vale MIC, Genaro IS, Saraiva-Romanholo BM, Leick EA, Martins MA, Prado CM, Tibério IFLC.

Front Pharmacol. 2018 Oct 4;9:1021. doi: 10.3389/fphar.2018.01021. eCollection 2018.


Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma.

Dos Santos TM, Righetti RF, Camargo LDN, Saraiva-Romanholo BM, Aristoteles LRCRB, de Souza FCR, Fukuzaki S, Alonso-Vale MIC, Cruz MM, Prado CM, Leick EA, Martins MA, Tibério IFLC.

Front Physiol. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183. eCollection 2018.


Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice.

de Genaro IS, de Almeida FM, Hizume-Kunzler DC, Moriya HT, Silva RA, Cruz JCG, Lopes RB, Righetti RF, de Paula Vieira R, Saiki M, Martins MA, Tibério IFLC, Arantes-Costa FM, Saraiva-Romanholo BM.

Sci Rep. 2018 Aug 22;8(1):12636. doi: 10.1038/s41598-018-30851-6. Erratum in: Sci Rep. 2018 Dec 12;8(1):17899.


Effects of Anti-IL-17 on Inflammation, Remodeling, and Oxidative Stress in an Experimental Model of Asthma Exacerbated by LPS.

Camargo LDN, Righetti RF, Aristóteles LRCRB, Dos Santos TM, de Souza FCR, Fukuzaki S, Cruz MM, Alonso-Vale MIC, Saraiva-Romanholo BM, Prado CM, Martins MA, Leick EA, Tibério IFLC.

Front Immunol. 2018 Jan 5;8:1835. doi: 10.3389/fimmu.2017.01835. eCollection 2017.


Ventilatory changes during the use of heat and moisture exchangers in patients submitted to mechanical ventilation with support pressure and adjustments in ventilation parameters to compensate for these possible changes: a self-controlled intervention study in humans.

Lucato JJJ, Cunha TMND, Reis AMD, Picanço PSA, Barbosa RCC, Liberali J, Righetti RF.

Rev Bras Ter Intensiva. 2017 Apr-Jun;29(2):163-170. doi: 10.5935/0103-507X.20170026. Portuguese, English.


A Plant Proteinase Inhibitor from Enterolobium contortisiliquum Attenuates Pulmonary Mechanics, Inflammation and Remodeling Induced by Elastase in Mice.

Theodoro-Júnior OA, Righetti RF, Almeida-Reis R, Martins-Oliveira BT, Oliva LV, Prado CM, Saraiva-Romanholo BM, Leick EA, Pinheiro NM, Lobo YA, Martins MA, Oliva ML, Tibério IF.

Int J Mol Sci. 2017 Feb 14;18(2). pii: E403. doi: 10.3390/ijms18020403.


The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI) Attenuates Elastase-Induced Emphysema in Mice.

Martins-Olivera BT, Almeida-Reis R, Theodoro-Júnior OA, Oliva LV, Neto Dos Santos Nunes N, Olivo CR, Vilela de Brito M, Prado CM, Leick EA, Martins Mde A, Oliva ML, Righetti RF, Tibério Ide F.

Mediators Inflamm. 2016;2016:5346574. doi: 10.1155/2016/5346574. Epub 2016 Aug 1.


Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung Diseases.

Santana FP, Pinheiro NM, Mernak MI, Righetti RF, Martins MA, Lago JH, Lopes FD, Tibério IF, Prado CM.

Mediators Inflamm. 2016;2016:2348968. doi: 10.1155/2016/2348968. Epub 2016 Jun 29. Review.


Sakuranetin reverses vascular peribronchial and lung parenchyma remodeling in a murine model of chronic allergic pulmonary inflammation.

Sakoda CPP, de Toledo AC, Perini A, Pinheiro NM, Hiyane MI, Grecco SDS, de Fátima Lopes Calvo Tibério I, Câmara NOS, de Arruda Martins M, Lago JHG, Righetti RF, Prado CM.

Acta Histochem. 2016 Jul;118(6):615-624. doi: 10.1016/j.acthis.2016.07.001. Epub 2016 Jul 15.


The effects of prenatal "psychological" stressor exposure on lung inflammation and hyperresponsiveness in adult rat offspring.

Barreto do Carmo MB, Righetti RF, Tibério IF, Hunziker MH.

Dev Psychobiol. 2016 Dec;58(8):1076-1086. doi: 10.1002/dev.21441. Epub 2016 Jul 1.


Influence of heat and moisture exchanger use on measurements performed with manovacuometer and respirometer in healthy adults.

Lucato JJ, Nogueira da Cunha TM, Rocha SS, Palmieri de Carvalho FM, Botega DC, Torquato JA, Gimenes AC, Righetti RF.

Multidiscip Respir Med. 2015 Dec 19;11:1. doi: 10.1186/s40248-015-0037-9. eCollection 2015.


Y-27632 is associated with corticosteroid-potentiated control of pulmonary remodeling and inflammation in guinea pigs with chronic allergic inflammation.

Pigati PA, Righetti RF, Possa SS, Romanholo BS, Rodrigues AP, dos Santos AS, Xisto DG, Antunes MA, Prado CM, Leick EA, Martins Mde A, Rocco PR, Tibério Ide F.

BMC Pulm Med. 2015 Aug 12;15:85. doi: 10.1186/s12890-015-0073-4.


Effects of Rho-kinase inhibition in lung tissue with chronic inflammation.

Righetti RF, Pigati PA, Possa SS, Habrum FC, Xisto DG, Antunes MA, Leick EA, Prado CM, Martins Mde A, Rocco PR, Tibério Ide F.

Respir Physiol Neurobiol. 2014 Feb 1;192:134-46. doi: 10.1016/j.resp.2013.12.012. Epub 2013 Dec 26.


Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model.

Aristoteles LR, Righetti RF, Pinheiro NM, Franco RB, Starling CM, da Silva JC, Pigati PA, Caperuto LC, Prado CM, Dolhnikoff M, Martins MA, Leick EA, Tibério IF.

BMC Pulm Med. 2013 Aug 15;13:52. doi: 10.1186/1471-2466-13-52.


Rho-kinase inhibition attenuates airway responsiveness, inflammation, matrix remodeling, and oxidative stress activation induced by chronic inflammation.

Possa SS, Charafeddine HT, Righetti RF, da Silva PA, Almeida-Reis R, Saraiva-Romanholo BM, Perini A, Prado CM, Leick-Maldonado EA, Martins MA, Tibério Ide F.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 1;303(11):L939-52. doi: 10.1152/ajplung.00034.2012. Epub 2012 Sep 21.

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