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Items: 29


Structural and functional consequences of age-related isomerization in α-crystallins.

Lyon YA, Collier MP, Riggs DL, Degiacomi MT, Benesch JLP, Julian RR.

J Biol Chem. 2019 May 10;294(19):7546-7555. doi: 10.1074/jbc.RA118.007052. Epub 2019 Feb 25.


Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4.

Zhu YX, Shi CX, Bruins LA, Wang X, Riggs DL, Porter B, Ahmann JM, de Campos CB, Braggio E, Bergsagel PL, Stewart AK.

Blood Cancer J. 2019 Feb 11;9(2):19. doi: 10.1038/s41408-019-0173-0.


Glycan Isomer Identification Using Ultraviolet Photodissociation Initiated Radical Chemistry.

Riggs DL, Hofmann J, Hahm HS, Seeberger PH, Pagel K, Julian RR.

Anal Chem. 2018 Oct 2;90(19):11581-11588. doi: 10.1021/acs.analchem.8b02958. Epub 2018 Sep 17.


Sequence and Solution Effects on the Prevalence of d-Isomers Produced by Deamidation.

Riggs DL, Gomez SV, Julian RR.

ACS Chem Biol. 2017 Nov 17;12(11):2875-2882. doi: 10.1021/acschembio.7b00686. Epub 2017 Oct 23.


IAP antagonists induce anti-tumor immunity in multiple myeloma.

Chesi M, Mirza NN, Garbitt VM, Sharik ME, Dueck AC, Asmann YW, Akhmetzyanova I, Kosiorek HE, Calcinotto A, Riggs DL, Keane N, Ahmann GJ, Morrison KM, Fonseca R, Lacy MQ, Dingli D, Kumar SK, Ailawadhi S, Dispenzieri A, Buadi F, Gertz MA, Reeder CB, Lin Y, Chanan-Khan AA, Stewart AK, Fooksman D, Bergsagel PL.

Nat Med. 2016 Dec;22(12):1411-1420. doi: 10.1038/nm.4229. Epub 2016 Nov 14.


A Novel Interaction between Pyk2 and MAP4K4 Is Integrated with Glioma Cell Migration.

Loftus JC, Yang Z, Kloss J, Dhruv H, Tran NL, Riggs DL.

J Signal Transduct. 2013;2013:956580. doi: 10.1155/2013/956580. Epub 2013 Sep 15.


Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.

De Leon JT, Iwai A, Feau C, Garcia Y, Balsiger HA, Storer CL, Suro RM, Garza KM, Lee S, Kim YS, Chen Y, Ning YM, Riggs DL, Fletterick RJ, Guy RK, Trepel JB, Neckers LM, Cox MB.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11878-83. doi: 10.1073/pnas.1105160108. Epub 2011 Jul 5.


Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling.

Riggs DL, Cox MB, Tardif HL, Hessling M, Buchner J, Smith DF.

Mol Cell Biol. 2007 Dec;27(24):8658-69. Epub 2007 Oct 15.


FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity.

Cox MB, Riggs DL, Hessling M, Schumacher F, Buchner J, Smith DF.

Mol Endocrinol. 2007 Dec;21(12):2956-67. Epub 2007 Aug 23.


Physiological role for the cochaperone FKBP52 in androgen receptor signaling.

Cheung-Flynn J, Prapapanich V, Cox MB, Riggs DL, Suarez-Quian C, Smith DF.

Mol Endocrinol. 2005 Jun;19(6):1654-66. Epub 2005 Apr 14.


Functional specificity of co-chaperone interactions with Hsp90 client proteins.

Riggs DL, Cox MB, Cheung-Flynn J, Prapapanich V, Carrigan PE, Smith DF.

Crit Rev Biochem Mol Biol. 2004 Sep-Dec;39(5-6):279-95. Review.


Functional comparison of human and Drosophila Hop reveals novel role in steroid receptor maturation.

Carrigan PE, Riggs DL, Chinkers M, Smith DF.

J Biol Chem. 2005 Mar 11;280(10):8906-11. Epub 2005 Jan 4.


Direct-to-consumer advertising: developing evidence-based policy to improve retention and comprehension.

Riggs DL, Holdsworth SM, McAvoy DR.

Health Aff (Millwood). 2004 Jan-Jun;Suppl Web Exclusives:W4-249-52.


The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor.

Nelson GM, Prapapanich V, Carrigan PE, Roberts PJ, Riggs DL, Smith DF.

Mol Endocrinol. 2004 Jul;18(7):1620-30. Epub 2004 Apr 7.


Multiple domains of the co-chaperone Hop are important for Hsp70 binding.

Carrigan PE, Nelson GM, Roberts PJ, Stoffer J, Riggs DL, Smith DF.

J Biol Chem. 2004 Apr 16;279(16):16185-93. Epub 2004 Feb 11.


C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90.

Cheung-Flynn J, Roberts PJ, Riggs DL, Smith DF.

J Biol Chem. 2003 May 9;278(19):17388-94. Epub 2003 Feb 27.


The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo.

Riggs DL, Roberts PJ, Chirillo SC, Cheung-Flynn J, Prapapanich V, Ratajczak T, Gaber R, Picard D, Smith DF.

EMBO J. 2003 Mar 3;22(5):1158-67.


Regulation of the RNA polymerase I and III transcription systems in response to growth conditions.

Clarke EM, Peterson CL, Brainard AV, Riggs DL.

J Biol Chem. 1996 Sep 6;271(36):22189-95.


Characterization of the components of reconstituted Saccharomyces cerevisiae RNA polymerase I transcription complexes.

Riggs DL, Peterson CL, Wickham JQ, Miller LM, Clarke EM, Crowell JA, Sergere JC.

J Biol Chem. 1995 Mar 17;270(11):6205-10.


The yeast RNA polymerase I promoter: ribosomal DNA sequences involved in transcription initiation and complex formation in vitro.

Kulkens T, Riggs DL, Heck JD, Planta RJ, Nomura M.

Nucleic Acids Res. 1991 Oct 11;19(19):5363-70.


Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes.

Kassavetis GA, Riggs DL, Negri R, Nguyen LH, Geiduschek EP.

Mol Cell Biol. 1989 Jun;9(6):2551-66.


Promoter domain mediates guanosine tetraphosphate activation of the histidine operon.

Riggs DL, Mueller RD, Kwan HS, Artz SW.

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9333-7.


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